Minnesota is currently home to 2110 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Minneapolis, Rochester, Saint Paul and Duluth. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
DECAMP 1 PLUS: Prediction of Lung Cancer Using Noninvasive Biomarkers
NCT04165564
Recruiting
DECAMP 1 PLUS aims to improve the efficiency of the diagnostic evaluation of patients with indeterminate pulmonary nodules (8-25 mm). Molecular biomarkers for lung cancer diagnosis measured in minimally invasive and non-invasive biospecimens may be able to distinguish between malignant or benign indeterminate pulmonary nodules in high-risk smokers. Ultimately, this study aims to validate molecular as well as clinical and imaging biomarkers of lung cancer in individuals with indeterminate lung no... Read More
Gender:
All
Ages:
46 years and above
Trial Updated:
05/16/2023
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Pulmonary Disease
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HeartShare: Combining Omics, Deep Phenotyping, and Electronic Health Records for Heart Failure Subtypes and Treatment Targets
NCT05873634
Recruiting
HeartShare is a comprehensive study of heart failure, a common and serious medical condition which occurs when the heart is unable to keep up with the demands of the body, resulting in shortness of breath, fluid retention, and fatigue. HeartShare aims to better classify heart failure into subtypes to help develop more personalized treatments for patients, with the hope that this will improve the lives of heart failure patients. To do this, HeartShare is bringing together a large amount of data (... Read More
Gender:
All
Ages:
30 years and above
Trial Updated:
05/15/2023
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Heart Failure, Heart Failure With Preserved Ejection Fraction
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Ketamine-enhanced Prolonged Exposure Therapy in PTSD
NCT04560660
Recruiting
The purpose of this study is to test the safety and efficacy of repeated doses of ketamine as compared to placebo to reduce symptoms of Posttraumatic Stress Disorder (PTSD) among Veteran receiving Prolonged Exposure Therapy.
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
05/15/2023
Locations: Minneapolis VA Health Care System, Minneapolis, MN, Minneapolis, Minnesota
Conditions: PTSD
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Comparison of Normothermia Maintenance Between Resistive Blanket and Forced Air Warming Systems in Renal Transplant Surgery
NCT04776954
Recruiting
The purpose of the study is to compare the effectiveness of resistive blanket warming to forced air warming in maintaining body temperature in participants undergoing renal transplantation.
Gender:
All
Ages:
Between 18 years and 90 years
Trial Updated:
05/11/2023
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Surgery, Temperature Change, Body
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Epidural and Dorsal Root Stimulation in Humans With Spinal Cord Injury
NCT04736849
Recruiting
A study to compare electrophysiologic activity of epidural stimulation and dorsal root ganglion stimulation, as well as quantify changes in motor performance with both types of stimulation over the course of 10 rehabilitation sessions.
Gender:
All
Ages:
22 years and above
Trial Updated:
05/10/2023
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Spinal Cord Injuries, Paraplegia, Tetraplegia, Paralysis
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The Oxford Risk Factors And Non-Invasive Imaging Study
NCT05169333
Recruiting
ORFAN is a prospective, multi-centre, multi-ethnic cohort observational study collecting CT scans, biological material and outcomes data, to develop and validate novel biomarkers of cardiometabolic and other disease risk.
Gender:
All
Ages:
Between 18 years and 99 years
Trial Updated:
05/09/2023
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Cardiovascular Diseases, Cardiovascular Risk Factors
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A Study of Stellate Ganglion Block for Prevention of Atrial Fibrillation
NCT05357690
Recruiting
The purpose of this study is to test if a nerve block procedure called a stellate ganglion block can help decrease the chance of atrial fibrillation after surgery. Atrial fibrillation is the abnormal, fast beating of the upper chambers of the heart. Stellate ganglion blockade has shown to decrease other types of abnormal heart rhythms as well as decrease the chance of atrial fibrillation.
Gender:
All
Ages:
60 years and above
Trial Updated:
05/08/2023
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Atrial Fibrillation
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Studying Health Outcomes After Treatment in Patients With Retinoblastoma
NCT03932786
Recruiting
This trial studies health outcomes after treatment in patients with retinoblastoma. Gathering health information over time from patients and family members through vision assessments, samples of tissue and saliva, and questionnaires may help doctors learn more about what causes retinoblastoma, identify long-term health outcomes for patients with retinoblastoma, and find out which therapies may be the best for treating retinoblastoma
Gender:
All
Ages:
All
Trial Updated:
05/08/2023
Locations: University of Minnesoa, Minneapolis, Minnesota
Conditions: Retinoblastoma, Cancer Survivor, Biological Sibling, Intraocular Retinoblastoma, Unilateral Retinoblastoma
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HOPE in Action Trial of HIV+ Deceased Donor Liver Transplants for HIV+ Recipients
NCT03734393
Recruiting
The primary objective of this study is to determine if an HIV-infected donor liver (HIVD+) transplant is safe with regards to major transplant-related and HIV-related complications
Gender:
All
Ages:
18 years and above
Trial Updated:
05/08/2023
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Hiv
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Study to Evaluate Biological & Clinical Effects of Significantly Corrected CFTR Function in Infants & Young Children
NCT04509050
Recruiting
This is a two-part, multi-center, prospective longitudinal, exploratory study of highly effective cystic fibrosis transmembrane conductance regulator (CFTR) modulators and their impact on children with cystic fibrosis (CF).
Gender:
All
Ages:
5 years and below
Trial Updated:
05/04/2023
Locations: Children's Hospitals and Clinics of Minnesota, Minneapolis, Minnesota
Conditions: Cystic Fibrosis
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Allo HSCT Using RIC and PTCy for Hematological Diseases
NCT05805605
Recruiting
This is a Phase II study following subjects proceeding with our Institutional non-myeloablative cyclophosphamide/ fludarabine/total body irradiation (TBI) preparative regimen followed by a related, unrelated, or partially matched family donor stem cell infusion using post-transplant cyclophosphamide (PTCy), sirolimus and MMF GVHD prophylaxis.
Gender:
All
Ages:
75 years and below
Trial Updated:
05/02/2023
Locations: Masonic Cancer Center at University of Minnesota, Minneapolis, Minnesota
Conditions: Acute Myelogenous Leukemia, Acute Lymphocytic Leukemia, Biphenotypic Acute Leukemia, Undifferentiated Leukemia, Prolymphocytic Leukemia, Chronic Myelogenous Leukemia, Plasma Cell Leukemia, Myelodysplastic Syndromes, Leukemia, Myeloid, Myelodysplastic Syndrome With Excess Blasts-1, Burkitt Lymphoma, Relapsed T-Cell Lymphoma, Relapsed Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, Marginal Zone Lymphoma, Follicular Lymphoma, Myeloproliferative Neoplasm, Myelofibrosis
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A Study of Intrathecal Hydromorphone for Pediatric Idiopathic Scoliosis Repair
NCT05552443
Recruiting
The purpose of this study is to identify a dose of intrathecal hydromorphone (opioid pain medicine) that optimizes pain control but minimizes side effects historically seen with this class of pain medications.
Gender:
All
Ages:
Between 10 years and 17 years
Trial Updated:
05/01/2023
Locations: Mayo Clinic Rochester, Rochester, Minnesota
Conditions: Pain Control
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