Minnesota is currently home to 2106 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Minneapolis, Rochester, Saint Paul and Duluth. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Hot Flashes and Neurovascular Function in Women
NCT05193968
Recruiting
Women who experience hot flashes are at greater risk for hypertension and other cardiovascular disease. Neurovascular control mechanisms are likely to play an important role in this relationship. As such, these studies are designed to provide a major step forward in understanding the link between hot flashes and neurovascular dysfunction and, by extension, cardiovascular disease in women.
Gender:
Female
Ages:
Between 40 years and 60 years
Trial Updated:
05/18/2023
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Hot Flashes, Menopause, Vasomotor System; Labile
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Rhythm Control and Potential Early Surgery for Tricuspid Regurgitation
NCT05045079
Recruiting
The purpose of this study is to understand the clinical impact of non-surgical and surgical treatment in atrial fibrillation induced tricuspid regurgitation (AFTR).
Gender:
All
Ages:
18 years and above
Trial Updated:
05/17/2023
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Severe Tricuspid Valve Regurgitation (Disorder)
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A Study of Endobiliary Radiofrequency Ablation in Malignant Biliary Obstructions
NCT05826639
Recruiting
The purpose of this study is to assess the impact of temperature-sensitive radiofrequency ablation (RFA) immediately before biliary stent placement on duration of biliary stent patency and re-intervention free survival. This is a research study meant to collect information to help other patients with malignant biliary strictures in the future.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/16/2023
Locations: Mayo Clinic Minnesota, Rochester, Minnesota
Conditions: Biliary Stricture
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JAB-3312 Based Combination Therapy in Adult Patients With Advanced Solid Tumors
NCT04720976
Recruiting
To evaluate the safety and tolerability of JAB-3312 administered in investigational regimens in adult participants with advanced solid tumors.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/16/2023
Locations: Research Site, Rochester, Minnesota
Conditions: Solid Tumor, NSCLC
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DECAMP 1 PLUS: Prediction of Lung Cancer Using Noninvasive Biomarkers
NCT04165564
Recruiting
DECAMP 1 PLUS aims to improve the efficiency of the diagnostic evaluation of patients with indeterminate pulmonary nodules (8-25 mm). Molecular biomarkers for lung cancer diagnosis measured in minimally invasive and non-invasive biospecimens may be able to distinguish between malignant or benign indeterminate pulmonary nodules in high-risk smokers. Ultimately, this study aims to validate molecular as well as clinical and imaging biomarkers of lung cancer in individuals with indeterminate lung no... Read More
Gender:
All
Ages:
46 years and above
Trial Updated:
05/16/2023
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Pulmonary Disease
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Ketamine-enhanced Prolonged Exposure Therapy in PTSD
NCT04560660
Recruiting
The purpose of this study is to test the safety and efficacy of repeated doses of ketamine as compared to placebo to reduce symptoms of Posttraumatic Stress Disorder (PTSD) among Veteran receiving Prolonged Exposure Therapy.
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
05/15/2023
Locations: Minneapolis VA Health Care System, Minneapolis, MN, Minneapolis, Minnesota
Conditions: PTSD
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Comparison of Normothermia Maintenance Between Resistive Blanket and Forced Air Warming Systems in Renal Transplant Surgery
NCT04776954
Recruiting
The purpose of the study is to compare the effectiveness of resistive blanket warming to forced air warming in maintaining body temperature in participants undergoing renal transplantation.
Gender:
All
Ages:
Between 18 years and 90 years
Trial Updated:
05/11/2023
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Surgery, Temperature Change, Body
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Epidural and Dorsal Root Stimulation in Humans With Spinal Cord Injury
NCT04736849
Recruiting
A study to compare electrophysiologic activity of epidural stimulation and dorsal root ganglion stimulation, as well as quantify changes in motor performance with both types of stimulation over the course of 10 rehabilitation sessions.
Gender:
All
Ages:
22 years and above
Trial Updated:
05/10/2023
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Spinal Cord Injuries, Paraplegia, Tetraplegia, Paralysis
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The Oxford Risk Factors And Non-Invasive Imaging Study
NCT05169333
Recruiting
ORFAN is a prospective, multi-centre, multi-ethnic cohort observational study collecting CT scans, biological material and outcomes data, to develop and validate novel biomarkers of cardiometabolic and other disease risk.
Gender:
All
Ages:
Between 18 years and 99 years
Trial Updated:
05/09/2023
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Cardiovascular Diseases, Cardiovascular Risk Factors
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HOPE in Action Trial of HIV+ Deceased Donor Liver Transplants for HIV+ Recipients
NCT03734393
Recruiting
The primary objective of this study is to determine if an HIV-infected donor liver (HIVD+) transplant is safe with regards to major transplant-related and HIV-related complications
Gender:
All
Ages:
18 years and above
Trial Updated:
05/08/2023
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Hiv
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Study to Evaluate Biological & Clinical Effects of Significantly Corrected CFTR Function in Infants & Young Children
NCT04509050
Recruiting
This is a two-part, multi-center, prospective longitudinal, exploratory study of highly effective cystic fibrosis transmembrane conductance regulator (CFTR) modulators and their impact on children with cystic fibrosis (CF).
Gender:
All
Ages:
5 years and below
Trial Updated:
05/04/2023
Locations: Children's Hospitals and Clinics of Minnesota, Minneapolis, Minnesota
Conditions: Cystic Fibrosis
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Protocol for a Research Sample Repository for Hematopoietic Cell Transplantation, Other Cellular Therapies and Marrow Toxic Injuries
NCT04920474
Recruiting
The primary purpose of the Research Sample Repository is to make blood samples available for research studies related to histocompatibility and hematopoietic cell transplantation (HCT) or other cellular therapy. Representatives of participating centers and investigators or research groups may request access to research samples contained in the Research Sample Repository for the purpose of conducting research including: investigating molecular explanations for histocompatibility or clinical out... Read More
Gender:
All
Ages:
All
Trial Updated:
05/01/2023
Locations: NMDP Biorepository, New Brighton, Minnesota
Conditions: Autologous Stem Cell Transplantation, Allogeneic Stem Cell Transplantation, Cellular Therapy, Marrow Toxic Injury
Register for Updates