Minnesota is currently home to 2056 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Minneapolis, Rochester, Saint Paul and Duluth. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Investigate the Efficacy and Safety of Farudodstat Compared With Its Placebo in Adult Alopecia Areata Participants
NCT05865041
Recruiting
The main purpose of this study is to measure the efficacy of farudodstat compared to placebo at Week 12 from the treatment start, in adult participants with Alopecia Areata (AA) with 30% or greater scalp hair loss.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/12/2023
Locations: 1 Site, Minneapolis, Minnesota
Conditions: Alopecia Areata
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Evaluation of the Effectiveness of Nail Genesis DLSO Product for Onychomycosis
NCT06074315
Recruiting
This is a Pre-IDE, prospective, multicenter, randomized, parallel-group, double-blind, vehicle- controlled study to evaluate safety and effectiveness of Nail Genesis DLSO Product for the treatment of DLSO compared with vehicle in infected great toenails in a total of 338 males and non-pregnant, non-lactating, females between 18 and 65 years of age (inclusive). Subjects will be randomized in a 2:1 ratio to receive either Nail Genesis DLSO Product or vehicle. Subject eligibility will be determine... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
12/06/2023
Locations: Minnesota Clinical Study Center, New Brighton, Minnesota
Conditions: Distal Lateral Subungual Onychomycosis, Onychomycosis
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Study of Narazaciclib (ON 123300) Plus Letrozole in Endometrial Cancer and Other Gynecologic Malignancies
NCT05705505
Recruiting
This study will assess the safety and efficacy of increasing doses of narazaciclib (ON 123300) in combination with the standard daily dose (2.5mg) of letrozole in patients with Recurrent Metastatic Low-grade Endometrioid Endometrial Cancer and other Gynecologic Malignancies.
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
12/05/2023
Locations: Minnesota Oncology Hematology, P.A., Minneapolis, Minnesota
Conditions: Endometrioid Endometrial Cancer
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Complex Abdominal, TAAA, Aortic Arch Aneurysm or Dissections With Fenestrated/Branched Stent Graft
NCT02089607
Recruiting
The purpose of this study is to gather safety and effectiveness of the Zenith t-Branch and customized physician-specified stent-graft with a combination of fenestrations and/or branches to repair aortic aneurysm.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/02/2023
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Thoracoabdominal Aortic Aneurysm, Aortic Arch Aneurysm, Complex Abdominal Aortic Aneurysm, Aortic Arch Dissection
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Complex Abdominal Aortic Aneurysm Repair With Fenestrated Stent Grafts
NCT01937949
Recruiting
The purpose of this study is to evaluate clinical outcomes and quality of life measures in treated by endovascular aortic repair of juxtarenal, suprarenal, and type IV thoracoabdominal aortic aneurysms using custom-made Cook Zenith® Fenestrated AAA Endovascular Graft.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/02/2023
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Juxtarenal Aortic Aneurysms, Suprarenal Aortic Aneurysms, Type IV Thoracoabdominal Aortic Aneurysms
Register for Updates
Efficacy of Daromun Neoadjuvant Intratumoral Treatment in Clinical Stage IIIB/C Melanoma Patients
NCT03567889
Recruiting
The trial aims to evaluate the efficacy of Daromun neoadjuvant treatment followed by surgery and adjuvant therapy to improve in a statistically significant manner the recurrence-free survival (RFS) of Stage IIIB/C melanoma patients with respect to the standard of care (surgery and adjuvant therapy).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/29/2023
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Melanoma Stage IIIB/C
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SynerFuse Spinal Fusion and Neuromodulation Proof of Concept Study
NCT04054401
Recruiting
The purpose of the study is to evaluate the safety and tolerability of DRG stimulation when placing a neurostimulator during the same procedure as implantation of spinal fixation with or without interbody cage systems in patients with chronic back and/or leg pain requiring single level spinal fusion.
Gender:
ALL
Ages:
Between 21 years and 80 years
Trial Updated:
11/21/2023
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Spinal Fusion, Radiculopathy Lumbar, Chronic Pain
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A Prospective Analysis of Long-Term Clinical Outcomes and 3D Spine Growth in Anterior Vertebral Body Tethering
NCT04914507
Recruiting
Anterior vertebral body tethering (AVBT) is a novel, minimally invasive, growth modulation technique that was recently approved by the FDA under a Humanitarian Device Exemption (HDE). The goal of AVBT is to control curve progression by applying compression on the convex side of the spine deformity. While there has been great initial enthusiasm about the technique as an alternate treatment option to spinal fusion for skeletally immature children with scoliosis, there is a need to better understan... Read More
Gender:
ALL
Ages:
18 years and below
Trial Updated:
11/14/2023
Locations: Gillette Children's Specialty Healthcare, Saint Paul, Minnesota
Conditions: Scoliosis Idiopathic
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Transcatheter Mitral Valve Repair for Inotrope Dependent Cardiogenic Shock
NCT05298124
Recruiting
Mitral regurgitation may be seen in the setting of cardiogenic shock. Transcatheter edge-to-edge repair (TEER) has been shown to improve outcomes in patients with chronic heart failure. Observational studies suggest improvements in clinical outcomes in patients with mitral regurgitation in the setting of cardiogenic shock; however, there remains a lack of randomized clinical data to support the use of TEER in cardiogenic shock. This study will be a multicenter, open-label, randomized-controlled... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/07/2023
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Cardiogenic Shock, Mitral Regurgitation
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NeuroGlove Anxiety and Depression Study
NCT06065787
Recruiting
This is a prospective, homebased, interventional clinical study containing 10 subjects who will be enrolled. Approximately 10 (10) subjects with active anxiety and depression symptoms will receive treatment using the NeuroGlove.
Gender:
ALL
Ages:
Between 18 years and 85 years
Trial Updated:
11/03/2023
Locations: NeuroGlove, Minneapolis, Minnesota
Conditions: Anxiety, Depression, Anxiety Depression, Depression, Anxiety
Register for Updates
Allogeneic ABCB5-positive Dermal Mesenchymal Stromal Cells for Treatment of Epidermolysis Bullosa (Phase III)
NCT05838092
Recruiting
The aim of this clinical trial is to investigate the safety and efficacy of allo-APZ2-OTS administered intravenously to subjects with recessive dystrophic epidermolysis bullosa (RDEB) compared to placebo.
Gender:
ALL
Ages:
6 months and above
Trial Updated:
10/27/2023
Locations: Masonic Cancer Center and Medical Center Minneapolis, Minneapolis, Minnesota
Conditions: Epidermolysis Bullosa
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Caloric Restriction and Activity to Reduce Chemoresistance in B-ALL
NCT05082519
Recruiting
This study is for older children, adolescents, and young adults with B-cell Acute Lymphoblastic Leukemia (B-ALL). Higher amounts of body fat is associated with resistance to chemotherapy in patients with B-ALL. Chemotherapy during the first month causes large gains in body fat in most people, even those who start chemotherapy at a healthy weight. This study is being done to find out if caloric restriction achieved by a personalized nutritional menu and exercise plan during routine chemotherapy... Read More
Gender:
ALL
Ages:
Between 10 years and 25 years
Trial Updated:
10/25/2023
Locations: Children's Hospitals and Clinics of Minnesota, Minneapolis, Minnesota
Conditions: B-cell Acute Lymphoblastic Leukemia, Obesity
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