Pennsylvania is currently home to 3294 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Philadelphia, Pittsburgh, Hershey and Allentown. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
VENOUS: A Translational Study of Enterococcal Bacteremia
NCT04410276
Recruiting
The purpose of this study is to assemble a multicenter prospective cohort of patients with enterococcal bloodstream infections (BSIs) to provide data on outcomes of patients with enterococcal BSIs for sample size calculations for future trials, as well as to characterize enterococcal isolates causing BSIs in order to comprehensively dissect the molecular epidemiology of infecting organisms for future studies.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/26/2020
Locations: University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania
Conditions: Enterococcal Bacteremia
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Cerclage for Twins With Short Cervical Length ≤ 15mm
NCT03340688
Recruiting
This is a multicenter randomized study designed to determine if ultrasound indicated cerclage reduces the incidence of spontaneous preterm birth \<34 weeks in asymptomatic women with twin gestations and cervical length ≤15mm, diagnosed by transvaginal ultrasound between 16 to 23 6/7 weeks of gestation.
Gender:
FEMALE
Ages:
Between 18 years and 60 years
Trial Updated:
04/23/2020
Locations: Thomas Jefferson University Hospital, Philadelphia, Pennsylvania
Conditions: Twin Pregnancy With Antenatal Problem, Preterm Birth, Short Cervix
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Randomized Trial of the Neochord DS1000 System Versus Open Surgical Repair
NCT02803957
Recruiting
The objective of this trial is to assess the safety and effectiveness of the study device in subjects with degenerative mitral valve disease receiving a mitral valve repair without cardiopulmonary bypass (treatment group) when compared to subjects receiving mitral valve repair using standard surgical techniques with cardiopulmonary bypass (control group).
Gender:
ALL
Ages:
21 years and above
Trial Updated:
12/04/2019
Locations: Pinnacle Health, Harrisburg, Pennsylvania
Conditions: Mitral Valve Insufficiency
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Smoking Cessation With Varenicline in Schizophrenia: Antipsychotic-Induced Neurological Symptoms as Correlates
NCT03495024
Recruiting
To test the feasibility of studying effects of smoking cessation with varenicline on antipsychotic drug-induced neurological side effects, we propose a 12 week pilot study of smoking cessation treatment with varenicline in 10 schizophrenia or schizoaffective disorder patients who are actively smoking and have pre-existing TD while receiving stable doses of antipsychotics. Subjects will be followed after a 2 week baseline period to assess changes in smoking status and neurological symptoms using... Read More
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
03/20/2019
Locations: Corporal Michael J Crescenz VA Medical Center, Philadelphia, Pennsylvania
Conditions: Schizophrenia, Schizoaffective Disorder, Tobacco Smoking, Tardive Dyskinesia, Parkinsonism
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A Registry Study of Breast Microseed Treatment
NCT02701244
Recruiting
For women diagnosed with early stage breast cancer, lumpectomy followed by radiation is a common treatment option. Radiation treatment is typically delivered to the whole breast, five times per week, for anywhere from 3 to 8 weeks. The radiation helps kill any cancer cells that may have been left over following the surgery but causes skin burns. Many studies have demonstrated that radiation to the whole breast is not necessary, that it can be delivered to a portion of the breast where the cancer... Read More
Gender:
FEMALE
Ages:
50 years and above
Trial Updated:
03/16/2018
Locations: Allegheny General Hospital, Pittsburgh, Pennsylvania
Conditions: Breast Neoplasms
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Study of Tumor Tissue Samples From Patients Who Have Undergone Surgery for Advanced Stage III or Stage IV Ovarian Epithelial Cancer
NCT01000259
Recruiting
This research study is looking at tumor tissue samples from patients who have undergone surgery for advanced stage III or stage IV ovarian epithelial cancer. Studying samples of tumor tissue from patients with cancer in the laboratory may help doctors learn how tumor infiltrating T cells can predict how patients will respond to treatment.
Gender:
FEMALE
Ages:
All
Trial Updated:
05/02/2017
Locations: Gynecologic Oncology Group, Philadelphia, Pennsylvania
Conditions: Stage IIIA Ovarian Cancer, Stage IIIB Ovarian Cancer, Stage IIIC Ovarian Cancer, Stage IV Ovarian Cancer
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