Pennsylvania is currently home to 3293 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Philadelphia, Pittsburgh, Hershey and Allentown. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Safety & Effectiveness of Autologous Regenerative Cell Therapy on Pain & Inflammation of Osteoarthritis of the Hip
NCT02844764
Recruiting
This is a prospective open-label clinical study of 50 patients to determine safety and treatment potential of autologous cell therapy for pain and inflammation associated with Osteoarthritis of the hip. Follow-up will consist of a larger sample including 4,000 patients.
Gender:
ALL
Ages:
Between 18 years and 90 years
Trial Updated:
08/04/2023
Locations: VivaTech International, Inc., Grove City, Pennsylvania
Conditions: Osteoarthritis
Register for Updates
Safety & Effectiveness of Autologous Regenerative Cell Therapy on Pain & Inflammation of Osteoarthritis of the Knee
NCT02844751
Recruiting
This is a prospective open-label clinical study of 50 patients to determine safety and treatment potential of autologous cell therapy for pain and inflammation associated with Osteoarthritis of the knee. Follow-up will consist of a larger sample including 4,000 patients.
Gender:
ALL
Ages:
Between 18 years and 90 years
Trial Updated:
08/04/2023
Locations: VivaTech International, Inc., Grove City, Pennsylvania
Conditions: Osteoarthritis
Register for Updates
Safety & Effectiveness of Autologous Regenerative Cell Therapy on Pain & Inflammation of Osteoarthritis of the Shoulder
NCT02844738
Recruiting
This is a prospective open-label clinical study of 50 patients to determine safety and treatment potential of autologous cell therapy for pain and inflammation associated with Osteoarthritis of the shoulder. Follow-up will consist of a larger sample including 4,000 patients.
Gender:
ALL
Ages:
Between 18 years and 90 years
Trial Updated:
08/04/2023
Locations: VivaTech International, Inc., Grove City, Pennsylvania
Conditions: Osteoarthritis
Register for Updates
A Clinical Trial of KVA12123 Treatment Alone and in Combination With Pembrolizumab In Advanced Solid Tumors (VISTA-101)
NCT05708950
Recruiting
The goal of this clinical trial is to test the safety and efficacy of KVA12123 alone or combined with pembrolizumab in patients with advanced solid tumors. The main questions this study aims to answer are: 1. What is the safety of KVA12123 when administered alone and in combination with pembrolizumab to advanced cancer patients? 2. What is an appropriate dose of KVA12123 to administer alone and in combination with pembrolizumab to advanced cancer patients in future clinical trials? Participant... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/11/2023
Locations: Thomas Jefferson University, Philadelphia, Pennsylvania
Conditions: Cancer, Solid Tumor, Melanoma, Carcinoma, Sarcoma, Lung Cancer, Prostate Cancer, Breast Cancer, Colo-rectal Cancer, Uterine Cancer, Pancreatic Cancer, Gastric Cancer, Esophageal Cancer, Thyroid Cancer, Ovarian Cancer, Kidney Cancer, Head and Neck Cancer
Register for Updates
Buprenorphine for Cancer Pain
NCT05910190
Recruiting
This study will evaluate patients on both buprenorphine and full agonist opioids (FAO) to assess for withdrawal symptoms. Patients will be evaluated by clinicians and using validated tools to assess for pain and withdrawal. At the same time, patients will use a CPM Rx application on their phone to track medication use.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/06/2023
Locations: Fox Chase Cancer Center, Philadelphia, Pennsylvania
Conditions: Cancer-Related Pain
Register for Updates
Canadian-American Spinal Cord Perfusion Pressure and Biomarker Study
NCT03911492
Recruiting
This multicenter study will enroll 100 patients with acute traumatic cervical and thoracic SCI who have a lumbar intrathecal catheter inserted within 24 hours of their injury. The lumbar intrathecal catheter will be inserted pre-operatively for the measurement of ITP and the collection of cerebrospinal fluid (CSF) samples. SCPP will be calculated as the difference between MAP and the ITP. There are two important distinct yet related objectives in this prospective interventional study. 1. Deter... Read More
Gender:
ALL
Ages:
17 years and above
Trial Updated:
06/30/2023
Locations: University Pittsburgh Medical Center, Pittsburgh, Pennsylvania
Conditions: Acute Spinal Cord Injury, Acute Spinal Paralysis, Spinal Cord Injuries, SPINAL Fracture
Register for Updates
Electromagnetic Fields Versus Placebo For Child-Pugh A and B Patients With Advanced Hepatocellular Carcinoma
NCT04797884
Recruiting
The primary goals of this study are to compare overall survival and quality of life in subjects with Child-Pugh A or B advanced hepatocellular carcinoma when treated with a device emitting radiofrequencies modulated at specific frequencies or with a device emitting unmodulated radiofrequencies.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/25/2023
Locations: Thomas Jefferson University Hospital, Sidney Kimmel Cancer Center, Philadelphia, Pennsylvania
Conditions: Hepatocellular Carcinoma
Register for Updates
Forging Sustainable Solutions for HIV Continuity of Care Through Medical-legal Partnerships
NCT05912842
Recruiting
The goal of this study is to test the Organizational Partnerships for Healthy Living (OPAHL) intervention through a feasibility and acceptability trial. OPAHL is an innovative, multilevel intervention package intended for health care organizations serving people living with HIV (PLWH). It was developed through a prior study (grant #: R21 MH115820) using intervention mapping methodology and community-scientific collaborative boards. OPAHL consists of: 1) training (7/8hours) for all MLP staff (cli... Read More
Gender:
ALL
Ages:
Between 18 years and 100 years
Trial Updated:
06/21/2023
Locations: TPAC, Philadelphia, Pennsylvania
Conditions: Organizational Partnerships for Healthy Living, Standard of Care
Register for Updates
Influence of Cognition on Activity and Participation in People With Stroke
NCT05919251
Recruiting
If a subject agrees to participate, the primary investigators will collect some basic information including age, height, and weight. Intake of some general questions regarding health will be performed and each subject will complete some tests that measure walking speed, cognition, and balance. During these tests participants will be asked to stand from a chair, walk up \& down a staircase, walk over objects in a forward, backward, and sideways directions, walk around objects in forward and backw... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/15/2023
Locations: Saint Joseph's University, Philadelphia, Pennsylvania
Conditions: Stroke, Cognitive Change, Neurological Injury, Cognitive Impairment, Activity, Motor
Register for Updates
Glioma Supra Marginal Incision Trial
NCT04737577
Recruiting
G-SUMIT is a pilot, phase II,randomized controlled trial to evaluate the feasibility of performing a large-scale trial in patients undergoing surgery for first-time diagnosis of high grade glioma (HGG) in a surgically favorable anatomical location to answer the following: Does extending the margin of resection 1 cm beyond visible enhanced volume on MRI result in (a) an increase in overall survival? (b) result in a similar rate of "clinically-significant" neurological worsening during 30 days po... Read More
Gender:
ALL
Ages:
Between 18 years and 85 years
Trial Updated:
06/15/2023
Locations: The Pennsylvania State University, University Park, Pennsylvania
Conditions: High Grade Glioma
Register for Updates
Use of the Impella BTR™ in Patients With Heart Failure: An Early Feasibility Study
NCT05291884
Recruiting
This is a prospective, multi-center, single-arm, early feasibility study that aims to evaluate the safety of the Impella BTR™ in adult patients requiring left-ventricular hemodynamic support, and to evaluate the effectiveness of the Impella BTR™ in supporting patients to recovery or their next therapy.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/07/2023
Locations: Allegheny General Hospital, Pittsburgh, Pennsylvania
Conditions: Heart Failure, Acute Decompensated Heart Failure
Register for Updates
AMP SCZ® Observational Study: PREDICT-DPACC
NCT05905003
Recruiting
The Accelerating Medicines Partnership® Schizophrenia (AMP® SCZ) is a large international collaboration to develop algorithms using a set of clinical and cognitive assessments, multi-modal biomarkers, and clinical endpoints that can be used to predict the trajectories and outcomes of individuals at clinical high risk (CHR) for psychosis and to advance the testing of pharmacological interventions for CHR individuals in need. The goal is to accurately predict which individuals are likely to remit,... Read More
Gender:
ALL
Ages:
Between 12 years and 30 years
Trial Updated:
06/06/2023
Locations: University of Pennsylvania, Philadelphia, Pennsylvania
Conditions: Clinical High Risk, Psychosis, Remission, Conversion
Register for Updates