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Asthma Clinical Trials
A listing of 93 Asthma clinical trials actively recruiting volunteers for paid trials and research studies in various therapeutic areas.
25 - 36 of 93
There are currently 93 active clinical trials seeking participants for Asthma research studies. The states with the highest number of trials for Asthma participants are California, Texas, Florida and Ontario.
Featured Trial
Chronic Cough Study
Recruiting
Are you tired of living with chronic cough? The ASPIRE Study is now looking to enroll people from all backgrounds to help research potential new treatment options for chronic cough. You are under no obligation to take part and health insurance is not required. Find out more today! We’d love to hear from you.
Conditions:
Chronic Cough
Refractory or Unexplained Chronic Cough
Cough
Asthma
Allergic Asthma
Featured Trial
A Study on the Efficacy, Safety, and Tolerability of an Investigational Drug in Participants with Severe Eosinophilic Asthma
Recruiting
The primary aim of this clinical trial is to study the potential effectiveness of an investigational drug in treating severe eosinophilic asthma, characterized by persistent symptoms and frequent flare-ups despite regular asthma medication. Secondary goals of this study include evaluating the safety and tolerability aspects of the investigational drug. To maintain objectivity, participants are randomly assigned into groups, receiving either the actual drug or a placebo. The outcome of this research will be instrumental in determining if the investigational drug stands as a possible treatment for those grappling with severe eosinophilic asthma. If you are interested in applying for this study, initiating contact will lead to direct engagement from the research site. They will provide more information on the study and answer any questions related to participation requirements, the potential risks and benefits, and any compensation on offer.
Conditions:
Asthma
All Conditions
Featured Trial
Studying an Investigational Medication in Adults with Eczema
Recruiting
The main objectives of this study are to evaluate the safety and effectiveness of an investigational medication in adults with moderate to severe atopic dermatitis, commonly known as eczema. The study aims to understand how different dosages of the investigational medication affect eczema flare ups. Participants will be randomly assigned to receive various dosages of the investigational medication or a placebo. Should you express interest, you will be contacted directly by the research site, who will provide further details and answer any questions you may have about study requirements, risks/benefits, and any compensation.
Conditions:
All Conditions
Dermatology
Eczema (Atopic dermatitis)
Featured Trial
High Triglyceride Clinical Research Study
Recruiting
Living with high triglycerides? See if our clinical study is right for you.
Don’t let financial stress hold you back. All clinical study-related assessments, care, and the investigational study drug are available at no cost. You could also be eligible for compensation for travel.
Don’t let financial stress hold you back. All clinical study-related assessments, care, and the investigational study drug are available at no cost. You could also be eligible for compensation for travel.
Conditions:
High Triglycerides
High Triglyceride Level
Hypertriglyceridemia
Elevated Triglycerides
Triglycerides High
Role of Genetic Factors in the Development of Lung Disease
Recruiting
This study is designed to evaluate the genetics involved in the development of lung disease by surveying genes involved in the process of breathing and examining the genes in lung cells of patients with lung disease.
The study will focus on defining the distribution of abnormal genes responsible for processes directly involved in different diseases affecting the lungs of patients and healthy volunteers.
Optional CT Sub-study
The standard CT scan will be compared to the low dose radiation CT s... Read More
Gender:
ALL
Ages:
Between 2 years and 90 years
Trial Updated:
03/04/2025
Locations: Suburban Hospital, Bethesda, Maryland +1 locations
A Study to Investigate the Efficacy and Safety of Tezepelumab Compared With Placebo in Children 5 to < 12 Years Old With Severe Asthma
Recruiting
To assess the efficacy and safety of tezepelumab in pediatric participants with severe uncontrolled asthma on medium to high-dose inhaled corticosteroids (ICS) and at least one additional asthma controller medication with or without oral corticosteroids.
Gender:
ALL
Ages:
Between 5 years and 11 years
Trial Updated:
03/04/2025
Locations: Research Site, Montgomery, Alabama +121 locations
Conditions: Asthma
The Effects of Positive Airway Pressure on the Mucolytic Effects of NAC (TEAM)
Recruiting
The goal of this clinical trial is to determine if positive pressure during inspiration will improve penetration of aerosolized N-Acetylcysteine (NAC) into airway mucus plugs in the lungs of patients with asthma or Chronic Obstructive Pulmonary Disease (COPD).
The main questions it aims to answer are:
* Does delivery of aerosolized NAC with positive inspiratory pressure have a greater effect on mucus plug burden in the lungs than delivery of NAC without positive pressure.
* Does delivery of ae... Read More
Gender:
ALL
Ages:
Between 18 years and 85 years
Trial Updated:
02/28/2025
Locations: UCSF Airway Clinical Research Center, San Francisco, California
Conditions: Asthma, COPD
Sample Collections From the Airways of Asthmatic Patients
Recruiting
Fiberoptic bronchoscopy is a procedure which involves passing a pencil-thin tube into the lung in order to collect fluid and cells from the airways. Fiberoptic bronchoscopy can collect cells from the walls of airways by gently brushing them (bronchial brushing). In addition, squirting small amounts of sterile water in to the airway and gently suctioning it back into the bronchoscope (bronchoalveolar lavage) collects cells.
In this study, researchers plan to perform these tests on patients with... Read More
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
02/27/2025
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Asthma
REIMAGINE - Real World EvaluatIon of Mepolizumab in Severe Asthma achievinG on Treatment clinIcal remissioN, a prospEctive Study
Recruiting
This is a prospective, real-world, single arm, global, multi-centre study to evaluate the effect of timely treatment with mepolizumab (NUCALA) to achieve clinical remission in adult participants with severe asthma with an eosinophilic phenotype (SA-EP).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/25/2025
Locations: GSK Investigational Site, Little Rock, Arkansas +65 locations
Conditions: Asthma
A Study to Assess the Effect of Dexpramipexole in Adolescents and Adults With Severe Eosinophilic Asthma (EXHALE-3)
Recruiting
The objective of this clinical study is to investigate the safety, tolerability, and efficacy of dexpramipexole in participants with inadequately controlled severe eosinophilic asthma.
Gender:
ALL
Ages:
Between 12 years and 99 years
Trial Updated:
02/24/2025
Locations: Research Site 30001-287, Mobile, Alabama +102 locations
Comparison of Microglial Activation in Severe Asthma and Healthy Controls
Recruiting
The goal of this clinical trial is to learn about how asthma influences brain function. The main questions it aims to answer are:
* How airway inflammation in asthma affects the brain; and,
* Whether airway inflammation in asthma is related to symptoms of depression and anxiety
Over the course of 3 visits, participants will:
* Complete questionnaires
* Complete computer tasks
* Undergo allergy skin test and breathing tests
* Give two blood samples
* Give a sputum sample
* Complete brain imagi... Read More
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
02/24/2025
Locations: Center for Healthy Minds, Madison, Wisconsin
Conditions: Asthma
A Study to Assess the Effect of Dexpramipexole in Participants With Severe Eosinophilic Asthma.
Recruiting
This study will assess the efficacy and safety of dexpramipexole as an adjunctive oral therapy in participants with inadequately controlled asthma with an eosinophilic phenotype and a history of asthma exacerbations.
Gender:
ALL
Ages:
Between 18 years and 99 years
Trial Updated:
02/24/2025
Locations: Research Site 20001-374, Bakersfield, California +321 locations
Impact of Metabolic Dysfunction and Mucus Plugging on Asthma Physiology
Recruiting
This is a single-center study of 80 subjects with asthma including those with obesity and metabolic dysfunction (MD), those with obesity and without metabolic dysfunction, those with severe asthma and mucus plugging and those with severe asthma and without mucus plugging. Screening data will be reviewed to determine participant eligibility. Participants who meet all inclusion criteria will participate in a cardiopulmonary exercise testing (CPET) visit to compare lung function markers and change... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/20/2025
Locations: UCSF Airway Clinical Research Center, San Francisco, California
Conditions: Asthma
Glucagon-Like Peptide-1 Receptor Agonist in the Treatment of Adult, Obesity-related, Symptomatic Asthma (GATA-3)
Recruiting
This is a randomized placebo-controlled trial of semaglutide, an FDA-approved therapy for the treatment of type 2 diabetes mellitus and obesity, in adults with symptomatic asthma despite the use of inhaled steroids and with excess body weight. This study will test the central hypothesis that semaglutide will improve asthma control and reduce airway inflammation due to direct effects on the respiratory tract in adult asthma associated with obesity.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/18/2025
Locations: Vanderbilt University Medical Center, Nashville, Tennessee
Conditions: Asthma
Prevention of Asthma Exacerbations Using Dupilumab in Urban Children and Adolescents
Recruiting
This is a multi-center, double-blind, placebo-controlled, randomized trial of dupilumab adjunctive therapy for prevention of asthma exacerbations in urban children and adolescents with T2-high exacerbation-prone asthma.
Gender:
ALL
Ages:
Between 6 years and 17 years
Trial Updated:
02/18/2025
Locations: Children's Hospital Colorado: Allergy Program, Aurora, Colorado +7 locations
Conditions: Asthma
Dose Ranging Study of Lunsekimig Compared With Placebo-control in Adult Participants With Moderate-to-severe Asthma
Recruiting
This is a Phase 2b, global, multicenter, randomized, double-blind, placebo-controlled, parallel group, dose ranging study to assess the efficacy, safety, and tolerability of add-on therapy with SC lunsekimig in adult participants aged 18 to 80 years, (inclusive) with moderate-to-severe asthma.
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
02/16/2025
Locations: Allergy, Asthma & Immunology Associates- Site Number : 8400009, Scottsdale, Arizona +155 locations
Conditions: Asthma
25 - 36 of 93