There are currently 100 active clinical trials seeking participants for Asthma research studies. The states with the highest number of trials for Autism participants are California, Texas, Florida and Ontario.
Terbutaline Sulfate in Adults With Asthma
NCT04973345
Recruiting
The overall aim in Part 1 is to compare the pharmacokinetic (PK)/pharmacodynamics (PD) relationship in intravenous (IV) versus subcutaneous (SQ) terbutaline sulfate to identify the optimal IV dosing range for use in Part 2. The overall aim in Part 2 is to evaluate the optimal IV dosing of terbutaline sulfate based on PD response and safety data.
Gender:
All
Ages:
Between 18 years and 50 years
Trial Updated:
01/02/2024
Locations: Duke Early Phase Research Unit (DEPRU), Durham, North Carolina
Conditions: Asthma
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AZithromycin Therapy in Preschoolers With a Severe Wheezing Episode Diagnosed at the Emergency Department
NCT04669288
Recruiting
AZ-SWED is a parallel group, double blind, placebo control efficacy clinical trial with two separate hypotheses. The trial will compare the 5-day outcome of preschool children presenting to an Emergency Department (ED) with an acute, severe wheezing episode and treated with either once daily oral Azithromycin (12 mg/kg/day for 5 days) or placebo. The AZ-SWED researchers will make separate comparisons in children in whom specific pathogenic bacteria are isolated from nasopharyngeal swabs, and in... Read More
Gender:
All
Ages:
Between 18 months and 60 months
Trial Updated:
01/02/2024
Locations: Children's Healthcare of Atlanta, Emory University, Atlanta, Georgia +7 locations
Conditions: Asthma, Wheezing
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Oxidative Stress in Asthma
NCT04512547
Recruiting
40% of all asthma patients in the US are obese. Obese asthmatics have more severe disease than lean asthmatics and do not respond as well to conventional anti-inflammatory therapies. This proposal will utilize 3D functional imaging with 129XeMRI and single cell RNA sequencing to study mechanisms driving regional airway remodeling and fibrosis in obese asthma subjects and in preclinical models of obese asthma.
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
12/18/2023
Locations: Duke Asthma Allergy and Airway Center, Durham, North Carolina
Conditions: Asthma, Obesity
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Asthma and Technology in Emerging African American Adults
NCT05445583
Recruiting
The purpose of the ATHENA Project is to test a mobile health intervention to help African American young adults better manage their asthma. The program has four components: 1) a web-based, mobile asthma program delivered to participants' mobile device, 2) meetings with an asthma nurse via video conference, 3) text messaging, and 4) physical activity tracking. Participants will be randomly assigned to one or more of these components to better meet the needs of young adults with asthma.
Gender:
All
Ages:
Between 18 years and 30 years
Trial Updated:
12/14/2023
Locations: Florida State University, Tallahassee, Florida +2 locations
Conditions: Asthma
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PatientSpot Formerly Known as ArthritisPower
NCT03840928
Recruiting
Patient Power is a patient research network and database (registry) to collect prospective information about demographics, self-reported diagnoses and medications, and willingness to participate in research from participants with rheumatoid arthritis (RA), spondyloarthritis (SpA), other musculoskeletal conditions, chronic neurological conditions like migraine, chronic pulmonary conditions like Chronic Obstructive Pulmonary Disease (COPD), asthma, autoimmune dermatological conditions such as psor... Read More
Gender:
All
Ages:
19 years and above
Trial Updated:
12/12/2023
Locations: Global Healthy Living Foundation, Upper Nyack, New York
Conditions: Rheumatoid Arthritis, Ankylosing Spondylitis, Fibromyalgia, Gout, Crohn Disease, Juvenile Idiopathic Arthritis, Lupus Erythematosus, Myositis, Osteoarthritis, Osteoporosis, Psoriasis, Psoriatic Arthritis, Scleroderma, Dermatomyositis, Inflammatory Bowel Diseases, Polymyositis, Axial Spondyloarthritis, Diffuse Idiopathic Skeletal Hyperostosis, Polymyalgia Rheumatica, Giant Cell Arteritis, Temporal Arteritis, Wegener, Relapsing Polychondritis, Undifferentiated Connective Tissue Disease, Spinal Cord Injuries, Alzheimer Disease, Amyotrophic Lateral Sclerosis, Ataxia, Bell Palsy, Brain Tumor, Cerebral Aneurysm, Epilepsy, Guillain-Barre Syndrome, Headache, Head Injury, Hydrocephalus, Lumbar Disc Disease, Meningitis, Multiple Sclerosis, Muscular Dystrophy, Neurocutaneous Syndromes, Parkinson Disease, Stroke, Cluster Headache, Tension-Type Headache, Chronic Obstructive Pulmonary Disease, Asthma, Lung Cancer, Cystic Fibrosis, Sleep Apnea, Eczema, Alopecia, Chronic Inflammation, Unstable Angina, Heart Attack, Heart Failure, Arrythmia, Valve Heart Disease, High Blood Pressure, Congenital Heart Disease, Peripheral Arterial Disease, Diabetes, Chronic Liver Disease, Obesity
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Spirometric Response to Bronchial Thermoplasty in Patients With Severe Asthma
NCT02241265
Recruiting
The investigators hypothesis is that there will be improvement in FEV1 in patients with severe asthma. This is a retrospective data study that reviews preexisting medical records; no patients will be enrolled.
Gender:
All
Ages:
Between 18 years and 99 years
Trial Updated:
12/06/2023
Locations: OUHSC, Oklahoma City, Oklahoma
Conditions: Asthma
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E-cigarettes for Harm Reduction in Adults With Asthma
NCT05278065
Recruiting
Smoking is the main cause of preventable disease and death in the US and impacts respiratory illnesses including COPD and asthma. However, little is known about the effects on smoking and lung health of substituting cigarettes with ENDS in adults with asthma. This project aims to test whether providing ENDS to adults with asthma will lead to substitution of smoking for ENDS, reduced dependence, and improved lung function so such knowledge can inform interventions to reduce the public health burd... Read More
Gender:
All
Ages:
Between 21 years and 65 years
Trial Updated:
11/30/2023
Locations: Center for Alcohol and Addiction Studies, Providence, Rhode Island
Conditions: Smoking, Asthma, Electronic Cigarette Use, Cigarette Smoking
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A Patient-Centered Asthma Management Communication Intervention for Rural Latino Children
NCT04633018
Recruiting
The purpose of this research is to develop and evaluate an mHealth communication intervention designed to improve asthma medication adherence amongst rural Latino children in South Carolina.
Gender:
All
Ages:
All
Trial Updated:
11/29/2023
Locations: Lancaster County School District, Lancaster, South Carolina
Conditions: Asthma
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Evaluating the Use of a Device Called Impulse Oscillometry in Participants With Vocal Cord Disorders or Asthma
NCT05246930
Recruiting
This study will determine if airway resistance to airflow and pressure, measured by Impulse Oscillometry, is impacted in subjects with vocal cord disorders and whether these measurements are different when compared to subjects with asthma.
Gender:
All
Ages:
18 years and above
Trial Updated:
11/27/2023
Locations: Mary Parkes Asthma and Allergy Center, Rochester, New York
Conditions: Breathing, Mouth, Lung Function Decreased, Vocal Cord Dysfunction, Laryngeal Obstruction, Asthma
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Viral Infection in Asthma (VIA) Study
NCT04380038
Recruiting
Often when people with asthma get a virus caused by the common cold (rhinovirus), they also experience an increase or worsening of their asthma symptoms. The purpose of this study is to see if the study medication dupilumab helps prevent those with mild to moderate asthma from having increased asthma symptoms, after being exposed to an experimental rhinovirus inoculation. This is a study about dupilumab which is a drug approved by the U.S. Food and Drug Administration (FDA) for treatment of mode... Read More
Gender:
All
Ages:
Between 18 years and 40 years
Trial Updated:
11/27/2023
Locations: University of Virginia, Charlottesville, Virginia
Conditions: Asthma
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Post-authorization Safety Study in North America to Monitor Pregnancy and Infant Outcomes Following Administration of Dupilumab During Planned or Unexpected Pregnancy
NCT04173442
Recruiting
The objective is to evaluate the potential effect of exposure to dupilumab in pregnancy compared to the primary comparison group of disease-matched pregnant women who are not exposed to dupilumab, and the secondary comparison group of healthy pregnant women. The primary outcome of the study is major structural defects, and the secondary outcomes of the study are spontaneous abortion/miscarriage, stillbirth, elective termination/abortion, premature delivery, small for gestational age, pattern of... Read More
Gender:
Female
Ages:
18 years and above
Trial Updated:
11/17/2023
Locations: Regeneron Research Site, La Jolla, California
Conditions: Atopic Dermatitis (AD), Asthma
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Vitamin C to Decrease Effects of Smoking in Pregnancy on Infant Lung Function (VCSIP) Longer Term Follow Up
NCT06106646
Recruiting
The overall aims of this protocol are to determine whether prenatal supplementation with vitamin C to pregnant smokers can improve pulmonary function at 10 years of age in their offspring. This is an additional continuation of the Vitamin C to Decrease Effects of Smoking in Pregnancy on Infant Lung Function (VCSIP) trial, to follow the offspring through 10 years of age. The hypothesis for this protocol is an extension of the VCSIP trial that supplemental vitamin C in pregnant smokers can signifi... Read More
Gender:
All
Ages:
Between 6 years and 16 years
Trial Updated:
11/17/2023
Locations: Indiana University, Indianapolis, Indiana +1 locations
Conditions: Asthma, Pulmonary Function, Wheezing, In Utero Nicotine
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