There are currently 100 active clinical trials seeking participants for Asthma research studies. The states with the highest number of trials for Autism participants are California, Texas, Florida and Ontario.
Nutrition for Asthmatics With Obesity
NCT05222451
Recruiting
This study will test the effect of diet on asthma in individuals with obesity.
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
11/15/2023
Locations: Pennington Biomedical Research Center, Baton Rouge, Louisiana
Conditions: Asthma, Obesity
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Wearable Auscultation Device Validation in Children
NCT06112080
Recruiting
This observational clinical study is an evaluation of a diagnostic tool through comparison. Similar to a validation study, the output of the RESP device will be compared to physician auscultation, surrogated by having an attending pulmonologist listen to blinded recordings.
Gender:
All
Ages:
Between 4 years and 17 years
Trial Updated:
11/10/2023
Locations: Lurie Children's Hospital of Chicago, Chicago, Illinois
Conditions: Asthma, Asthma in Children, Wheezing, Pediatric Asthma
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IL13 Signaling in Allergic Asthma
NCT05478824
Recruiting
This study will investigate the role of dupilumab in the treatment of asthma with comorbid obesity. It is hypothesized that in airway epithelial cells, unique transcriptomic and proteomic expression patterns distinguish allergic and non-allergic patients with asthma and obesity and drive significant differential responses to dupilumab. It is further hypothesized that dupilumab will increase interleukin-13 receptor alpha 2 (IL-13Rα2) levels and/or signaling activity on airway epithelial cells iso... Read More
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
11/08/2023
Locations: Duke Asthma Allergy and Airway Center, Durham, North Carolina
Conditions: Asthma, Allergic, Asthma, Obesity
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Pilot Study to Identify the Mediators and Inflammatory Cell Surface Receptors Involved in Allergic Airway Inflammation
NCT00595491
Recruiting
Asthma is a heterogeneous disorder in which multiple potential inflammatory pathways contribute to airway obstruction. The biological basis for airway inflammation is the subject of intensive investigation. This work is designed to identify airway factors that are responsible for recruiting cells and associate their airway presence with atopy and asthma.
Gender:
All
Ages:
Between 18 years and 50 years
Trial Updated:
11/03/2023
Locations: Massachusetts General Hospital, Boston, Massachusetts
Conditions: Asthma
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Mechanism(s)of Airflow Limitation in Moderate-severe Persistent Asthma
NCT00576069
Recruiting
The purpose of this study is to evaluate the site and mechanisms responsible for expiratory airflow limitation in chronic, treated, non-smoking, stable asthmatics with moderate to severe persistent expiratory airflow obstruction. Treatment will include inhaled corticosteroids and long acting beta2agonists and long acting muscarinic antagonists. We are interested in determining whether the large and/or small airways are the predominant site of airflow limitation. We are also interested in determi... Read More
Gender:
All
Ages:
Between 10 years and 95 years
Trial Updated:
10/25/2023
Locations: Arthur F Gelb Medical Corporation, Lakewood, California
Conditions: Asthma
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Mechanism(s) of Airflow Limitation During Exacerbation of Asthma
NCT01225913
Recruiting
The purpose of this study is to evaluate the site and mechanisms responsible for expiratory airflow limitation in chronic, treated, non-smoking, stable asthmatics with moderate to severe persistent expiratory airflow obstruction. Treatment will include inhaled corticosteroids and long acting beta2agonists. The investigators are interested in determining whether the large and/or small airways are the predominant site of airflow limitation. The investigators are also interested in determining whet... Read More
Gender:
All
Ages:
Between 10 years and 80 years
Trial Updated:
10/25/2023
Locations: Arthur F Gelb Medical Corporation, Lakewood, California
Conditions: Asthma
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An Open-Label Extension Study of GSK3511294 (Depemokimab) in Participants Who Were Previously Enrolled in 206713 (NCT04719832) or 213744 (NCT04718103)
NCT05243680
Recruiting
The purpose of this open-label 12-month extension study is to continue to characterize the long-term safety, efficacy and immunogenic profile of GSK3511294 (Depemokimab) in participants with severe asthma with an eosinophilic phenotype following completion of clinical studies 206713 or 213744.
Gender:
All
Ages:
12 years and above
Trial Updated:
10/13/2023
Locations: GSK Investigational Site, Lancaster, California +131 locations
Conditions: Asthma
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Simultaneously Implementing Pathways for Improving Asthma, Pneumonia, and Bronchiolitis Care for Hospitalized Children
NCT05206695
Recruiting
This study's objective is to identify and test pragmatic and sustainable strategies for implementing a multi-condition clinical pathway intervention for children hospitalized with asthma, pneumonia, or bronchiolitis in community hospitals. The hypothesis is that the multi-condition pathway intervention will be associated with significantly greater increases in clinicians' adoption of evidence-based practices compared to control. The study is a pragmatic, cluster-randomized trial in US community... Read More
Gender:
All
Ages:
17 years and below
Trial Updated:
10/12/2023
Locations: University of California, San Francisco, San Francisco, California
Conditions: Asthma, Pneumonia, Bronchiolitis
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Vaginal Microbiome Exposure and Immune Responses in C-section Infants
NCT03567707
Recruiting
The purpose of this research study is to assess at how differences in the microbiome (naturally occurring bacteria) of a baby may protect, or put a baby at risk, for allergic problems. The microbiome refers to the thousands of bacteria and molds that live in and on our bodies. The microbiome plays an important role in our health. Differences in the microbiome can affect our immune system in ways that might make some people more likely to get allergies and asthma. Early life events and exposures... Read More
Gender:
Female
Ages:
Between 18 years and 45 years
Trial Updated:
10/10/2023
Locations: Mount Sinai West, New York, New York +1 locations
Conditions: Allergic Diseases, Asthma
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Innate Immunity in Allergic Asthma
NCT06068335
Recruiting
The purpose of this study is to determine whether a potential type 2 signature, obtained through stimulation of cell lines with various allergens in vitro, correlates with an allergic or asthmatic disease state ex vivo. This type 2 signature will be multi-hierarchical in nature and will be comprised cell surface receptor expression, pathway activation, and gene upregulation.
Gender:
All
Ages:
18 years and above
Trial Updated:
10/09/2023
Locations: University of Central Florida, Orlando, Florida
Conditions: Asthma
Register for Updates
Measuring the Effect of Dupilumab Treatment on Mucociliary Clearance (MCC) in Subjects With Moderate to Severe Asthma
NCT04743791
Recruiting
Single center, randomized, placebo- controlled study to assess change in mucociliary clearance of moderate to severe asthma patients after treatment with dupilumab or placebo.
Gender:
All
Ages:
18 years and above
Trial Updated:
10/04/2023
Locations: The University of Pittsburgh Asthma Institute at UPMC, Pittsburgh, Pennsylvania
Conditions: Asthma
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AIM2ACT: A Mobile Health Tool to Help Adolescents Self-Manage Asthma
NCT04448002
Recruiting
The aim is to test the efficacy of AIM2ACT and long-term maintenance of treatment effects in a fully-powered randomized controlled trial with 160 early adolescents with poorly controlled persistent asthma, ages 12-15 years, and a caregiver
Gender:
All
Ages:
Between 12 years and 70 years
Trial Updated:
09/15/2023
Locations: UF Health Pediatrics, Gainesville, Florida
Conditions: Asthma
Register for Updates