Asthma Clinical Trials

Asthma clinical trials aim to understand the causes of asthma, and to test out new medications and even lifestyle and dietary changes to treat the disease.

Joining a clinical trial provides patients a greater control over their health, and gives them access to healthcare provided by teams of experts in their fields. Trials are carried out in universities, hospitals, and research centers. If you are interested in joining a clinical trial to find new ways to manage your asthma, ask your doctor about clinical trials in your area or contact organizations to find out about trials available to you.

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Asthma
306 trials found

Comparison of Flutter and PEP Mask on Chest Clearance, Dyspnea in Elderly Asthmatic Patients

NCT05618873

This study will be a Randomized controlled and will be conducted in Allied Hospital, Faisalabad. The study will be completed within the duration of 10 months. Convenience sampling study technique will be used to collect the data. The sample size of 30 patients will be taken in this study to find the effect of flutter and PEP mask therapy on chest clearance and dyspnea. Patients will be allocated randomly in two groups and 15 patients in each group. Group A will get flutter device therapy. Group ...

Conditions: Asthma
Phase: Not Applicable

Evaluation of the Efficacy of Respicure® (Resveratrol / Quercetin) in the Management of Respiratory Conditions Including Asthma,COPD and Long COVID.

NCT05601180

Interventional, Prospective, National, Multicentre, Randomised, Open-label, Controlled Clinical Study Comparing Two Parallel Groups, One Control Arm (Standard Treatment) Versus Intervention Arm (Standard Treatment + Study Product) Evaluating the Efficacy of Respicure® 0.38% /0.38% (Resveratrol / Quercetin) Phytotherapy Product From BEKER Laboratories as an add-on Treatment in the Management of Respiratory Conditions Including Asthma (Partially Controlled),COPD (Stage A, B, C and D) and long COVI ...

Conditions: Asthma, Chronic Obstructive Pulmonary Disease, Long COVID
Phase: Not Applicable

A Trial of SHR-1905 in Subjects With Severe Uncontrolled Asthma

NCT05593250

This study is a phase 2 study of SHR-1905 in subjects with severe uncontrolled asthma. The purpose of the study is to evaluate efficacy and safety of SHR-1905 in subjects with severe uncontrolled asthma.

Conditions: Asthma

Vocal Cord Responses During Hyperventilation in Normal Individuals and in Mild and Severe Asthmatics.

NCT05565430

The Investigators aim to: Study the effect of hyperventilation on the development of paradoxical vocal cord movement (PVCM) in healthy individuals and in patients with mild and severe asthma, Relate PVCM to airway symptoms and measurements of intra- and extra-thoracic airway hyperresponsiveness (ET-AHR), Evaluate the effects of inhaled anti-cholinergic agents on PVCM induced by hyperventilation. Hypotheses: In health PVCM will not occur in response to hyperventilation, In asthma PVCM will occ ...

Conditions: Hyperventilation, Larynx, Asthma

PT027 Compared to PT007 in Patients With Asthma With Mannitol-induced Acute Airway Obstruction

NCT05555290

A study evaluating efficacy and safety of repeated doses of PT027 compared to PT007 in patients with asthma and acute airway obstruction induced by repeated mannitol challenges

Conditions: Asthma

BURAN: Benralizumab on Airway Dynamics in Severe Eosinophilic Asthma Using Functional Respiratory Imaging

NCT05552508

This study will assess the effects of benralizumab on airway dynamics in severe eosinophilic asthma in terms of quantitative computed tomography (CT)-derived measurements of pulmonary structure and function using the Functional Respiratory Imaging (FRI) platform.

Conditions: Asthma

Implementation of Evidence-based Breathing Retraining for Patients With Asthma in Region Zealand

NCT05531370

This study aims to implement the evidence-based intervention breathing retraining into clinical care of patients with symptomatic asthma irrespective of asthma severity or comorbidities, and in a diverse multicentre setting to evaluate implementation outcomes. This will meet patients' needs and improve health and life situation in patients with uncontrolled asthma. Further, the study will evaluate implementation outcomes.

Conditions: Asthma
Phase: Not Applicable

A Comparison of PT027 vs PT007 Used as Needed in Participants With Asthma

NCT05505734

This is a US study comparing the efficacy and safety of BDA MDI [Budesonide/Albuterol Sulfate (BDA) metered dose inhaler (MDI)] with AS [Albuterol Sulfate] MDI, both are administered as needed for up to 12 months.

Conditions: Asthma

Mepolizumab Pharmacokinetics Among Patients With Severe Asthma

NCT05495932

Asthma is a chronic disease characterized by inflammation and obstruction of the airways. Identification of the mechanisms of action of corticosteroids has made it possible to define the type 2 inflammation present in nearly 80% of patients with asthma. Monoclonal antibodies (MAb) in severe asthma target type-2 inflammation. Mepolizumab is a humanized IgG1 (immunoglobulin gamma-1) kappa subclass monoclonal antibody directed specifically against interleukin 5 (IL-5). It acts specifically on eosi ...

Conditions: Asthma
Phase: Not Applicable

Evaluation of Physical Activity in Asthmatic Subjects

NCT05486689

Asthma is a chronic disease, which leads to a number of adverse outcomes, including lower levels of physical activity (PA). Physical inactivity is an important risk factor, increasing PA has become a patient-centred goal for the treatment of subjects with asthma. Data provided by activity monitors are commonly used to measure daily PA. A recent systematic review showed that adults with asthma had lower levels of total, moderate and vigorous physical activity than those without asthma. There are ...

Conditions: Asthma, Physical Activity
Phase: Not Applicable

Patient Education in Pregnant Women With Asthma

NCT05459012

Pregnancy may impact treatment adherence in women with asthma. This is a major risk factor for asthma exacerbation, which may have an important impact for both women and the babies. This study aims to evaluate the impact of a targeted patient education action tailored for pregnant women with asthma.

Conditions: Asthma

Avoidable Hospitalizations/ Emergency Department Visits- Systematic Review and Meta-synthesis of Qualitative Research

NCT05456906

The aim of the study is to synthesize qualitative evidence related to preventable hospitalizations/ emergency department visits from the perspectives of patients, their families/caregivers, health care providers, and stakeholders, in the hope to identify generalizable conclusions about why social risk factors matter to preventable hospitalizations/ emergency department visits

Conditions: Diabetes, Heart Failure, Chronic Obstructive Pulmonary Disease, Asthma, Hypertension, Urinary Tract Infections, Pneumonia, Bacterial