There are currently 100 active clinical trials seeking participants for Asthma research studies. The states with the highest number of trials for Autism participants are California, Texas, Florida and Ontario.
A Study of Patients With Chronic Disease
NCT04263727
Recruiting
TARGET-RWE is a 10-year, international, longitudinal, observational study of patients with chronic disease designed to specifically address important clinical questions that remain incompletely answered from registration trials. The protocol will follow a master protocol design in which a shared study infrastructure supports progressive development of the registry across the spectrum of chronic diseases.
Gender:
All
Ages:
All
Trial Updated:
08/24/2023
Locations: Asthma and Allergy Associates, PC, Colorado Springs, Colorado +4 locations
Conditions: Asthma, Chronic Obstructive Pulmonary Disease, Idiopathic Pulmonary Fibrosis, IPF, COPD, Respiratory Disease
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Mechanisms of Interferon Gamma-primed Mesenchymal Stromal Cells (MSCs) for Moderate-to-severe Persistent Asthma
NCT05035862
Recruiting
This study is a two strata, dose escalation Phase I clinical trial designed to assess the safety and determine the maximal tolerated dose (MTD) of allogenic cord tissue derived MSCs (cMSCs, stratum 1) and allogeneic, interferon-γ primed bone marrow MSCs (γMSCs, stratum 2). Each stratum is designed to independently accrue 3 children at a dose level 1 of 2x106 cells/kg and 6 children at dose level 2 of 10x106 cells/kg, resulting in 9 children in each stratum. The primary objectives are to determin... Read More
Gender:
All
Ages:
Between 18 years and 30 years
Trial Updated:
08/23/2023
Locations: Children's Healthcare of Atlanta, Atlanta, Georgia
Conditions: Asthma
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Physical Activity Intervention for Black Women With Asthma
NCT05726487
Recruiting
Physical inactivity is associated with poor asthma control and quality of life, and greater health care utilization. Rates of physical inactivity, asthma, and asthma mortality among Black women are higher than those of their White counterparts. Our formative work identified barriers to PA among Black women with asthma including a lack of social support, self-efficacy, unsafe neighborhood and fear related to experiences with life-threatening asthma exacerbations. Given the unique barriers to PA a... Read More
Gender:
Female
Ages:
18 years and above
Trial Updated:
08/11/2023
Locations: University of Illinois Chicago, Chicago, Illinois +1 locations
Conditions: Asthma
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Glucagon-Like Peptide-1 Receptor Agonist in the Treatment of Adult, Obesity-related, Symptomatic Asthma (GATA-3)
NCT05254314
Recruiting
This is a randomized placebo-controlled trial of semaglutide, an FDA-approved therapy for the treatment of type 2 diabetes mellitus and obesity, in adults with symptomatic asthma despite the use of inhaled steroids and with excess body weight. This study will test the central hypothesis that semaglutide will improve asthma control and reduce airway inflammation due to direct effects on the respiratory tract in adult asthma associated with obesity.
Gender:
All
Ages:
18 years and above
Trial Updated:
07/14/2023
Locations: Vanderbilt University Medical Center, Nashville, Tennessee
Conditions: Asthma
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Primary Care Implementation and Evaluation of Coach McLungs
NCT05059210
Recruiting
The goal of this study is to evaluate the implementation of the Coach McLungsSM shared decision making (SDM) intervention into primary care across a large healthcare system. Coach McLungsSM is a virtual evidence-based asthma intervention with built-in asthma education and clinical decision support. All asthma patients aged 5-17 who attend these practices will be assessed for uncontrolled asthma. Asthma exacerbations attributed to emergency department visits, hospitalizations, and oral steroid us... Read More
Gender:
All
Ages:
Between 5 years and 17 years
Trial Updated:
06/28/2023
Locations: Atrium Health, Charlotte, North Carolina
Conditions: Asthma
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Registry of Asthma Characterization and Recruitment 3 (RACR3)
NCT05272241
Recruiting
This is a multi-center, non-interventional registry to create and maintain a database of participants to serve as a recruitment source for current and future DAIT NIAID-sponsored Childhood Asthma in Urban Settings (CAUSE) studies.
Gender:
All
Ages:
All
Trial Updated:
06/20/2023
Locations: Children's Hospital Colorado: Allergy Program, Aurora, Colorado +6 locations
Conditions: Asthma
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Prevention of Asthma Exacerbations Using Dupilumab in Urban Children and Adolescents
NCT05347771
Recruiting
This is a multi-center, double-blind, placebo-controlled, randomized trial of dupilumab adjunctive therapy for prevention of asthma exacerbations in urban children and adolescents with T2-high exacerbation-prone asthma.
Gender:
All
Ages:
Between 6 years and 17 years
Trial Updated:
06/20/2023
Locations: Children's Hospital Colorado: Allergy Program, Aurora, Colorado +6 locations
Conditions: Asthma
Register for Updates
Addressing Quality of Life, Clinical Outcomes, and Mechanisms in Uncontrolled Asthma Following the DASH Dietary Pattern
NCT05251402
Recruiting
The goal of the ALOHA trial is to investigate the efficacy of improved diet quality following a DASH behavioral intervention that has shown promising results in adults with uncontrolled asthma. DASH stands for Dietary Approaches to Stop Hypertension. This healthy diet is known to help people with high blood pressure manage their health. But physicians do not know if the DASH diet can also benefit patients with uncontrolled asthma. Researchers in the ALOHA study are trying to find out the answer... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
06/15/2023
Locations: Department of Medicine, Chicago, Illinois +1 locations
Conditions: Asthma
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Impact of Metabolic Dysfunction and Mucus Plugging on Asthma Physiology
NCT05757583
Recruiting
This is a single-center study of 80 subjects with asthma including those with obesity and metabolic dysfunction (MD), those with obesity and without metabolic dysfunction, those with severe asthma and mucus plugging and those with severe asthma and without mucus plugging. Screening data will be reviewed to determine participant eligibility. Participants who meet all inclusion criteria will participate in a cardiopulmonary exercise testing (CPET) visit to compare lung function markers and change... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
06/13/2023
Locations: UCSF Airway Clinical Research Center, San Francisco, California
Conditions: Asthma
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Microglia Activation in Asthma
NCT04307667
Recruiting
The primary purpose of this study is to provide preliminary data to determine if an acute increase in airway inflammation, provoked by an inhaled allergen challenge, is associated with an increase in microglial activation and may inform whether individuals with asthma, in the long-term, are at increased risk for neurodegeneration, cognitive decline, and forms of dementia. Though in the long-term airway inflammation may be associated with neurodegenerative processes, these changes reflect the acc... Read More
Gender:
All
Ages:
Between 18 years and 50 years
Trial Updated:
06/13/2023
Locations: University of Wisconsin Madison, Madison, Wisconsin
Conditions: Asthma
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Advancing Health Information Exchange (HIE) During Inter-hospital Transfer (IHT) to Improve Patient Outcomes
NCT05443321
Recruiting
Sub-optimal transfer of clinical information during inter-hospital transfer (IHT, the transfer of patients between acute care hospitals) is common and can lead to patient harm. To address this problem, the investigators will use key stakeholder input to refine and implement an interoperable health information exchange platform that integrates with the electronic health record and improves the reliability of and access to necessary clinical information in three use cases involving transfer of pat... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/18/2023
Locations: Brigham & Women's Hospital, Boston, Massachusetts
Conditions: Infections, Heart Failure, COPD Exacerbation, Asthma, Gastrointestinal Diseases, Cardiac Event, Arrythmia, Renal Failure, Renal Disease, Rheumatic Diseases, Urologic Diseases, Neurologic Disorder, Hematologic Diseases, Oncology Problem, Shock, Critical Illness
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PrecISE (Precision Interventions for Severe and/or Exacerbation-Prone Asthma) Network Study
NCT04129931
Recruiting
The primary objective of this study is to evaluate several interventions given to participants with severe asthma. Interventions are administered in a crossover manner with 16-week treatment periods followed by 8 to 16 week washout.
Gender:
All
Ages:
12 years and above
Trial Updated:
05/16/2023
Locations: Mayo Clinic Scottsdale, Scottsdale, Arizona +28 locations
Conditions: Asthma
Register for Updates