There are currently 298 active clinical trials seeking participants for Cancer research studies. The states with the highest number of trials for Cancer participants are California, Texas, New York and Florida.
Immune Profiling for Cancer Immunotherapy Response
NCT06116032
Recruiting
In patients clinically treated with FDA-approved immunotherapy the investigators will assess the predictive value of pre- and on-treatment 1) immune-methylation profiling across cancer types, and 2) immune-methylation profiling and cytokine profiling within cancer types.
Gender:
All
Ages:
18 years and above
Trial Updated:
11/06/2023
Locations: Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire
Conditions: Cancer, Tumor, Solid, Hematologic Malignancy, Blood Cancer
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A Study of OR2805, a Monoclonal Antibody Targeting CD163, Alone and in Combination With Anticancer Agents
NCT05094804
Recruiting
This is an open-label, multicenter, first-in-human dose-escalation and expansion Phase 1-2 study designed to determine the safety, tolerability, pharmacokinetics, pharmacodynamics, and preliminary anti-tumor activity of OR2805 administered as a monotherapy and in combination with anti-cancer agents in subjects with advanced solid tumors.
Gender:
All
Ages:
18 years and above
Trial Updated:
10/31/2023
Locations: HonorHealth Research Institute, Scottsdale, Arizona +2 locations
Conditions: Cancer, Tumor, Solid, Malignant Neoplasm, Metastatic Cancer, Advanced Solid Tumor, Non Small Cell Lung Cancer, Melanoma, Head and Neck Squamous Cell Carcinoma, Leiomyosarcoma, Liposarcoma
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A Study of OR502, a Monoclonal Antibody Targeting LILRB2, Alone and in Combination With Anticancer Agents
NCT06090266
Recruiting
This is an open-label, multicenter, first-in-human dose-escalation and expansion Phase 1-2 study designed to determine the safety, tolerability, pharmacokinetics, pharmacodynamics, and preliminary anti-tumor activity of OR502 administered as a monotherapy and in combination with cemiplimab in subjects with advanced solid tumors.
Gender:
All
Ages:
18 years and above
Trial Updated:
10/31/2023
Locations: NEXT Austin, Austin, Texas +3 locations
Conditions: Cancer, Tumor, Solid, Malignant Neoplasm, Metastatic Cancer, Advanced Solid Tumor, Platinum-resistant Ovarian Cancer, Cutaneous Squamous Cell Carcinoma
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Using a Smartphone App to Target Current Mental Health Symptoms of Anxiety and Depression
NCT06037382
Recruiting
This is a prevention intervention study that will examine the efficacy of a smartphone-based intervention in decreasing cancer risk by targeting mental health risk factors of anxiety and depression.
Gender:
All
Ages:
Between 40 years and 64 years
Trial Updated:
10/27/2023
Locations: Dartmouth College, Hanover, New Hampshire
Conditions: Depression, Anxiety, Cancer
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INTERogating Cancer for Etiology, Prevention and Therapy Navigation
NCT06008392
Recruiting
The purpose of this study is to evaluate the integration of cancer pan-genetic testing into a cancer clinical practice and understand both its use and effect in "real world" practice conditions.
Gender:
All
Ages:
18 years and above
Trial Updated:
10/26/2023
Locations: Mayo Clinic in Arizona, Scottsdale, Arizona +2 locations
Conditions: Cancer, Cancer Gene Mutation, PAN Gene Mutation
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Using Information Technology to Improve Outcomes for Children Living With Cancer
NCT04789720
Recruiting
This proposed study plans to develop and evaluate a patient-oriented, technology-based, symptom monitoring system that reports symptoms experienced by children with cancer to their parents and health care providers.
Gender:
All
Ages:
Between 8 years and 17 years
Trial Updated:
10/25/2023
Locations: Ann & Robert H. Lurie Childrens Hospital of Chicago, Chicago, Illinois
Conditions: Cancer
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Food and Microbiome Longitudinal Investigation (FAMiLI)
NCT03293758
Recruiting
The NYU Human Microbiome Study Cohort is designed to improve understanding of the role of human microbiome in health and disease. This study will serve as a critical NYU biorepository resource for research on human genetics and the microbiome in health and disease
Gender:
All
Ages:
40 years and above
Trial Updated:
10/24/2023
Locations: New York University School of Medicine, New York, New York
Conditions: Cancer, Cardiovascular Diseases
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Treating Pain in Children With Cancer: Pain Buddy
NCT03384134
Recruiting
The purpose of this study is to examine the feasibility of the ambulatory monitoring protocol, called Pain Buddy, in documenting children's pain, symptoms and quality of life while receiving outpatient chemotherapy. The long term goal of Pain Buddy is to help doctors, nurses, and parents get the information they need to give children treatments for pain and symptom management that work. Using Pain Buddy, we aim to quantify the prevalence and intensity of daily pain and symptom episodes in childr... Read More
Gender:
All
Ages:
Between 8 years and 18 years
Trial Updated:
10/24/2023
Locations: University of California, Irvine, Orange, California
Conditions: Cancer
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A New Psychotherapy Intervention for Older Cancer Patients
NCT04452825
Recruiting
This study is being done to see if a new psychotherapy intervention called Cancer and Aging: Reflections for Elders (CARE) can effectively treat depression and distress in older cancer patients. CARE is a 5-session intervention that takes place over the phone. This study will compare CARE with the Social Work and Supportive Counseling (SWSC) intervention, which also takes place over the phone. SWSC is a standard psychotherapeutic intervention that has been shown to be a supportive and effective... Read More
Gender:
All
Ages:
70 years and above
Trial Updated:
10/23/2023
Locations: Memorial Sloan Kettering Cancer Center, New York, New York
Conditions: Cancer
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Oral AMXT 1501 Dicaprate in Combination With IV DFMO
NCT05500508
Recruiting
A Phase 1B/2A study will be conducted to establish safety and dose level of AMXT 1501 dicaprate in combination with IV DFMO, in cancer patients.
Gender:
All
Ages:
12 years and above
Trial Updated:
10/18/2023
Locations: Mayo Clinic - Arizona, Phoenix, Arizona +6 locations
Conditions: Cancer, Solid Tumor, Solid Carcinoma, Advanced Cancer, DIPG Brain Tumor, Ovary Cancer, Breast Cancer, Papillary Thyroid Cancer, Head and Neck Cancer, Gastric Cancer, Nsclc, Mesotheliomas Pleural, Mesothelioma Peritoneum, Esophageal Cancer, Diffuse Midline Glioma, H3 K27M-Mutant, Endometrial Cancer, Cervical Cancer, Melanoma, Colorectal Cancer, Glioma, Malignant
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Study of Combined Decompressive Spine Radiosurgery and Pembrolizumab
NCT05204290
Recruiting
The purpose of this research study is to find out what effects (good and bad) Pembrolizumab and radiosurgery have on participants with high-grade epidural disease of the spine.
Gender:
All
Ages:
18 years and above
Trial Updated:
10/16/2023
Locations: Wake Forest Baptist Comprehensive Cancer Center, Winston-Salem, North Carolina
Conditions: Epidural Spinal Tumors, Cancer
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Intra- and Inter-fraction Changes in Radiation Therapy
NCT02344121
Recruiting
Analysis to quantify intra-fraction, inter-fraction and post-treatment changes in tumor target volumes and surrounding normal organs in radiation therapy.
Gender:
All
Ages:
All
Trial Updated:
10/12/2023
Locations: Froedtert Hospital, Milwaukee, Wisconsin
Conditions: Cancer
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