There are currently 281 active clinical trials seeking participants for Cancer research studies. The states with the highest number of trials for Cancer participants are California, Texas, New York and Florida.
Developing a Culturally Relevant Supportive Care Program for Black Patients Dealing With Advanced Cancer
NCT05763797
Recruiting
To determine the feasibility of implementing a culturally adapted mind-body intervention (Meditation-Based Support-Adapted; MBS-A) as a supportive care strategy in Black patients diagnosed with a stage III-IV solid malignancy. To target the specific needs of Black advanced cancer patients, we will first conduct formative research that includes quantitative surveys and in-depth interviews of patients and their primary caregivers. The purpose of this formative research is to determine the interven... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/07/2025
Locations: M D Anderson Cancer Center, Houston, Texas
Conditions: Cancer
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An Internet-based Program to Help Cancer Survivors Manage Pain
NCT04462302
Recruiting
To determine whether an Internet-based pain coping skills program plus enhanced usual care, compared to enhanced usual care alone, yields significant improvements in the co-primary outcomes of pain severity (as measured by the Brief Pain Inventory (BPI)) and pain interference (also measured by the BPI) from baseline to the post-intervention assessment for cancer survivors with persistent pain.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/07/2025
Locations: Mercy Hospital Fort Smith, Fort Smith, Arkansas +149 locations
Conditions: Cancer
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A Dyadic Intervention for Young Adult Patients With Cancer and Their Partner Caregivers
NCT06172907
Recruiting
The purpose of this pilot study is to examine the feasibility and acceptability of a brief psychotherapy intervention to improve psychosocial coping and maintain couple relationships among young adults (aged 25-39) with cancer and their caregiving partners.
Gender:
ALL
Ages:
Between 25 years and 39 years
Trial Updated:
08/06/2025
Locations: Massachusetts General Hospital Cancer Center, Boston, Massachusetts +3 locations
Conditions: Cancer, Survivorship, Caregiver Burden, Psychological Distress, Coping Skills, Couples
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Met Non Small Cell Cancer Registry (MOMENT)
NCT05376891
Recruiting
The purpose of this multi-national disease registry is to collect prospectively (with longitudinal follow-up) high-quality, standardized, and contemporaneous data to capture changes in the non-small cell lung cancer (NSCLC) treatment landscape and outcomes over time. The registry will capture data on participants; demographic, clinical characteristics (including biomarker data), treatment patterns, and effectiveness and safety outcomes for advanced NSCLC with mesenchymal-epithelial transition e... Read More
Gender:
ALL
Ages:
All
Trial Updated:
08/06/2025
Locations: Holy Cross Health, Fort Lauderdale, Florida +63 locations
Conditions: Cancer
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A Decisional Intervention for Older Adults With Acute Myeloid Leukemia and Their Caregivers
NCT06697600
Recruiting
This is a multicenter randomized controlled trial that assesses the efficacy of a decisional intervention \[University of Rochester-Geriatric Oncology assessment for Acute myeloid Leukemia (UR-GOAL)\] compared to an attention control.
Gender:
ALL
Ages:
60 years and above
Trial Updated:
08/05/2025
Locations: University of Alabama at Birmingham, Division of Hematology and Oncology, Birmingham, Alabama +3 locations
Conditions: Oncology, Myeloid Leukemia, Acute, Cancer
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A Randomized Trial of a Mobile Health Exercise Intervention for Older Adults With Myeloid Neoplasms
NCT04981821
Recruiting
This is a phase 2 randomized controlled trial (RCT) to assess the preliminary efficacy of the a mobile health exercise intervention (GO-EXCAP) versus a chemotherapy education control in 100 older patients with MN receiving outpatient chemotherapy on physical function and patient-reported outcomes (fatigue, mood, and quality of life). We will also explore the effect of the intervention on TNFα and related cytokine gene promoter methylation and their gene and protein expression.
Gender:
ALL
Ages:
60 years and above
Trial Updated:
08/05/2025
Locations: University of Rochester Medical Center/Wilmot Cancer Institute, Rochester, New York
Conditions: Cancer, Myeloid Neoplasm
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Implement and Test Visual Consent Template and Process
NCT06804837
Recruiting
The investigators plan to conduct a stepped wedge randomized control trial to implement and test the consent template and process in three studies. Randomization will occur at the research coordinator/research team level. Each participating research team member will begin in the standard consent arm of the study. Subsequently, they will be randomized to the visual key information page arm at staggered time points to undergo training and begin using the visual key information page with patients w... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/05/2025
Locations: Washington University School of Medicine, Saint Louis, Missouri +2 locations
Conditions: Cancer, Alzheimer Disease
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Galleri® in the Medicare Population.
NCT05673018
Recruiting
This multi-center comparative prospective cohort study is designed to assess the real world clinical impact, including safety and test performance, of Galleri®, a blood-based multi-cancer early detection (MCED) test. The study will seek to enroll approximately 20% of the study participants from under-represented minority populations (e.g., racial / ethnic minority groups, socioeconomically disadvantaged populations, rural populations).
Gender:
ALL
Ages:
50 years and above
Trial Updated:
08/05/2025
Locations: Sutter Valley Hospitals Auburn, Auburn, California +38 locations
Conditions: Cancer
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A Phase I/II Study of Zotiraciclib for Recurrent Malignant Gliomas With Isocitrate Dehydrogenase 1 or 2 (IDH1 or IDH2) Mutations
NCT05588141
Recruiting
Background: Diffuse gliomas are tumors that affect the brain and spinal cord. Gliomas that develop in people with certain gene mutations (IDH1 or IDH2) are especially aggressive. Better treatments are needed. Objective: To see if a study drug (zotiraciclib) is effective in people with recurrent diffuse gliomas who have IDH1 or IDH2 mutations. Eligibility: People aged 15 years and older with diffuse gliomas that returned after treatment. They must also have mutations in the IDH1 or IDH2 gene... Read More
Gender:
ALL
Ages:
15 years and above
Trial Updated:
08/05/2025
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Brain Tumor, Cancer
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Opiophobia in Adults With Advanced Cancer
NCT07093567
Recruiting
To explore the barriers and fears related to use of opioids among a population of adult outpatients with advanced cancer who continue to experience pain after receiving a prescription for opioid analgesia and hypothesized associations among opiophobia, anxiety, depression, pain intensity, pain interference, and opioid medication adherence.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/04/2025
Locations: The University of Texas M. D. Anderson Cancer Center, Houston, Texas
Conditions: Cancer
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Assessing Claims of Cannabis as an Anti-cancer Agent (CATA)
NCT07107607
Recruiting
The purpose of the study is to find out how cannabis may help control cancer growth by reviewing medical records of patients who report cannabis helped treat their cancer.
Gender:
ALL
Ages:
All
Trial Updated:
08/04/2025
Locations: HealthPartners Institute Cancer Research Center, Saint Louis Park, Minnesota
Conditions: Cancer, Cancer (With or Without Metastasis)
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Perceptions of Hospital Care at Home for Patients With Cancer: A Qualitative Study of Cancer Providers, Patients and Caregivers.
NCT05694650
Recruiting
The objective of this qualitative research study is to assess the knowledge, attitudes and beliefs of cancer care providers, patients with cancer and caregivers regarding hospital care at home. We aim to conduct qualitative interviews to inform implementation of future on oncology hospital care at home programs
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/04/2025
Locations: M D Anderson Cancer Center, Houston, Texas
Conditions: Cancer
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