There are currently 274 active clinical trials seeking participants for Cancer research studies. The states with the highest number of trials for Cancer participants are California, Texas, New York and Florida.
Tumor Related Epilepsy
Recruiting
Background: Some people with brain tumors have seizures related to the tumor. This is called tumor-related epilepsy. Usually brain tumors are treated by removing as much of the brain tumor as possible without causing problems. Researchers think this may improve the outcome for people with brain tumors. It may completely relieve or greatly reduce the number of seizures they have. Objectives: To evaluate people with brain tumors that are associated with seizures and to offer surgical treatment.... Read More
Gender:
ALL
Ages:
Between 8 years and 99 years
Trial Updated:
04/18/2025
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Epilepsy, Cancer, Brain Neoplasm
A Phase 2 Clinical Trial Evaluating the Efficacy and Safety of Dual Immune Checkpoint Inhibition With Anti-PD-L1 (Atezolizumab) and Anti-TIGIT (Tiragolumab) in Cancer of Unknown Primary
Recruiting
The goal of this clinical research study is to learn if the combination of atezolizumab and tiragolumab can help to control cancers of unknown primary. The safety and effects of this drug combination will also be studied
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/18/2025
Locations: The University of Texas M. D. Anderson Cancer Center, Houston, Texas
Conditions: Cancer
Intra- and Inter-fraction Changes in Radiation Therapy
Recruiting
Analysis to quantify intra-fraction, inter-fraction and post-treatment changes in tumor target volumes and surrounding normal organs in radiation therapy.
Gender:
ALL
Ages:
All
Trial Updated:
04/18/2025
Locations: Froedtert Hospital, Milwaukee, Wisconsin
Conditions: Cancer
MDMA-assisted Therapy for Adjustment Disorder (AD) in Dyads of Patients With Cancer and a Concerned Significant Other
Recruiting
The goal of this clinical trial is to assess feasibility, tolerability and preliminary effectiveness of MDMA-assisted therapy for adjustment disorder (AD) in 10 dyads of patients with cancer and a concerned significant other (CSO) (20 participants total). Participants will undergo an 8-week treatment period which will include two doses of MDMA, two Preparatory Sessions and four Integrative Sessions of non-drug therapy.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/17/2025
Locations: Sunstone Medical, PC, Rockville, Maryland
Conditions: Cancer, Adjustment Disorders
Two Doses of Psilocybin for the Treatment of MDD in Adults With Cancer
Recruiting
This is a Phase 2, single-center study to explore the efficacy, safety, and tolerability of up to two 25-mg doses of psilocybin administered at an interval of 9 to 10 weeks in patients with MDD and cancer. This two-part study will administer a fixed dose (25 mg) of psilocybin in a double-blind, randomized, placebo-controlled portion (Dosing Session 1) and subsequently allow rollover into an open-label portion (Dosing Session 2; fixed dose of psilocybin, 25 mg) for patients who do not achieve rem... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/17/2025
Locations: Sunstone Medical, PC, Rockville, Maryland
Conditions: Cancer, Major Depressive Disorder
A Dose Finding Phase 1 of Sarilumab Plus Capecitabine in HER2/Neu-Negative Metastatic Breast Cancer and a Single-arm, Historically-controlled Phase 2 Study of Sarilumab Plus Capecitabine in Stage I-III Triple Negative Breast Cancer With High-Risk Residual Disease (EMPOWER)
Recruiting
This study looks to advance a novel and potent strategy to eliminate minimal residual disease (MRD) in triple negative breast cancer (TNBC) present even after multimodal treatment, thereby improving survival and increasing cure rate in this aggressive cancer. Patients with locally advanced TNBC are at high risk of developing lethal metastatic disease within 2 years of diagnosis, especially for those without a pathologic complete response (pCR) after neoadjuvant chemotherapy. The high risk occurs... Read More
Gender:
ALL
Ages:
Between 18 years and 99 years
Trial Updated:
04/16/2025
Locations: Los Angeles General Medical Center, Los Angeles, California +2 locations
Conditions: Breast, Metastatic, Triple Negative, Cancer, Disseminated Tumor Cell
Met Non Small Cell Cancer Registry (MOMENT)
Recruiting
The purpose of this multi-national disease registry is to collect prospectively (with longitudinal follow-up) high-quality, standardized, and contemporaneous data to capture changes in the non-small cell lung cancer (NSCLC) treatment landscape and outcomes over time. The registry will capture data on participants; demographic, clinical characteristics (including biomarker data), treatment patterns, and effectiveness and safety outcomes for advanced NSCLC with mesenchymal-epithelial transition e... Read More
Gender:
ALL
Ages:
All
Trial Updated:
04/15/2025
Locations: Holy Cross Health, Fort Lauderdale, Florida +63 locations
Conditions: Cancer
Pan Tumor Rollover Study
Recruiting
Main Objective of this study is to examine long-term safety of nivolumab monotherapy including combinations and other cancer therapies in various tumor types.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/15/2025
Locations: University of Arizona College of Medicine, Tucson, Arizona +392 locations
Conditions: Cancer
Occupational Cancer Screening in Firefighters: A Pilot Study Within the Inova Health System
Recruiting
The purpose of this study is to further understand the clinical impact and follow-up steps that may be required based on using whole-body Magnetic Resonance Imaging (MRI) or whole-body ultrasound and blood tests to detect multiple cancers in firefighters. This study involves an investigational test (cancer blood test) that has not been approved by the U.S. Food and Drug Administration (FDA). Whole-body MRI and whole-body ultrasound are approved by the U.S. Food and Drug Administration (FDA) to... Read More
Gender:
ALL
Ages:
Between 35 years and 85 years
Trial Updated:
04/15/2025
Locations: Inova Schar Cancer - Saville Cancer Screening and Prevention Center, Fairfax, Virginia
Conditions: Cancer
Food and Microbiome Longitudinal Investigation (FAMiLI)
Recruiting
The NYU Human Microbiome Study Cohort is designed to improve understanding of the role of human microbiome in health and disease. This study will serve as a critical NYU biorepository resource for research on human genetics and the microbiome in health and disease
Gender:
ALL
Ages:
40 years and above
Trial Updated:
04/14/2025
Locations: New York University School of Medicine, New York, New York
Conditions: Cancer, Cardiovascular Diseases
Galleri in the Medicare Population
Recruiting
This multi-center comparative prospective cohort study is designed to assess the real world clinical impact, including safety and test performance, of Galleri®, a blood-based multi-cancer early detection (MCED) test. The study will seek to enroll approximately 20% of the study participants from under-represented minority populations (e.g., racial / ethnic minority groups, socioeconomically disadvantaged populations, rural populations).
Gender:
ALL
Ages:
50 years and above
Trial Updated:
04/14/2025
Locations: Sutter Valley Hospitals Auburn, Auburn, California +31 locations
Conditions: Cancer
Understanding Patient Experience Among Asians at MD Anderson
Recruiting
The purpose of this research study is to understand barriers to and facilitators of a positive patient experience for Asian patients.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/14/2025
Locations: MD Anderson Cancer Center, Houston, Texas
Conditions: Cancer