There are currently 280 active clinical trials seeking participants for Cancer research studies. The states with the highest number of trials for Cancer participants are California, Texas, New York and Florida.
Precision Cancer Medicine for Advanced Cancer Through High-throughput Sequencing
Recruiting
Precision Cancer Medicine for Advanced Cancer Through High-throughput Sequencing
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/04/2025
Locations: Ohio State University Wexner Medical Center, Columbus, Ohio
Conditions: Cancer
Building Family Caregiver Skills Using a Simulation-Based Intervention for Care of Cancer Patients
Recruiting
The purpose of this study is to learn whether an education and support program can help caregivers feel more confident in technical and communication skills needed to care for a person with cancer. Patients with cancer and their caregivers face many challenges. These include learning about cancer and its treatment, coping with symptoms from illness and treatment side effects, making adjustments to usual activities, and managing the emotional effects of having a serious illness. This study is tes... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/09/2024
Locations: University Hospitals Cleveland Medical Center, Case Comprehensive Cancer Center, Cleveland, Ohio +1 locations
Conditions: Cancer
Promoting Access, Resources and Treatment Through Novel and Equitable Solutions for Cancer Care
Recruiting
The purpose of this research is to evaluate a novel, integrated approach to providing navigation services to improve cancer outcomes and quality of life.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/24/2024
Locations: Case Comprehensive Cancer Center, Cleveland, Ohio
Conditions: Cancer
Lattice Radiotherapy for Dose-Escalated Palliation of Bulky Tumors
Recruiting
The purpose of this research study is to determine if lattice radiation therapy (LRT) will provide better treatment for bulky (large) tumors than current standard of care radiotherapy.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/20/2024
Locations: University of Cincinnati Medical Center, Cincinnati, Ohio
Conditions: Cancer, Metastatic Cancer, Locally Advanced, Locally Advanced Solid Tumor, Locally Advanced Carcinoma
A Phase I/II Study of Zotiraciclib for Recurrent Malignant Gliomas With Isocitrate Dehydrogenase 1 or 2 (IDH1 or IDH2) Mutations
Recruiting
Background: Diffuse gliomas are tumors that affect the brain and spinal cord. Gliomas that develop in people with certain gene mutations (IDH1 or IDH2) are especially aggressive. Better treatments are needed. Objective: To see if a study drug (zotiraciclib) is effective in people with recurrent diffuse gliomas who have IDH1 or IDH2 mutations. Eligibility: People aged 15 years and older with diffuse gliomas that returned after treatment. They must also have mutations in the IDH1 or IDH2 gene... Read More
Gender:
ALL
Ages:
15 years and above
Trial Updated:
03/21/2025
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Brain Tumor, Cancer
Tumor Related Epilepsy
Recruiting
Background: Some people with brain tumors have seizures related to the tumor. This is called tumor-related epilepsy. Usually brain tumors are treated by removing as much of the brain tumor as possible without causing problems. Researchers think this may improve the outcome for people with brain tumors. It may completely relieve or greatly reduce the number of seizures they have. Objectives: To evaluate people with brain tumors that are associated with seizures and to offer surgical treatment.... Read More
Gender:
ALL
Ages:
Between 8 years and 99 years
Trial Updated:
03/21/2025
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Epilepsy, Cancer, Brain Neoplasm
Patient-Centered Assessment of Symptoms and Outcomes
Recruiting
Background: The cause of fatigue is not well understood. It can be felt differently by different people. Some people think there are different types of fatigue, with different causes. Researchers think a therapy to treat one type of fatigue in one condition should be able to treat that type of fatigue in other conditions. Objective: To understand the types of fatigue. Eligibility: Adults 18 and older who have felt fatigue for more than a month, and non-fatigued adults Design: Participants... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/20/2025
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Fatigue, Cancer, CFS, ME/CFS, Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, Lupus, Systemic Lupus Erthematosus, Sjogrens
Pan Tumor Rollover Study
Recruiting
Main Objective of this study is to examine long-term safety of nivolumab monotherapy including combinations and other cancer therapies in various tumor types.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/20/2025
Locations: University of Arizona College of Medicine, Tucson, Arizona +389 locations
Conditions: Cancer
Rehabilitation Outcomes Study
Recruiting
This pilot health services interventional study aims to prospectively assess the effectiveness of a pre-treatment rehabilitation (prehabilitation) program across a diverse cohort of adult cancer patients via a randomized pilot trial. Upon screening and identification of high-risk features through a central navigation process, patients referred to oncology clinics will be approached to participate in tailored prehabilitation interventions. The study will track and analyze functional outcomes and... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/19/2025
Locations: The N.C. Cancer Hospital, Chapel Hill, North Carolina
Conditions: Cancer, Malignant Tumor
INTERogating Cancer for Etiology, Prevention and Therapy Navigation
Recruiting
This study is being done to identify markers and causes of cancer by analyzing patient's DNA (i.e., genetic material), RNA, plasma, tissues, or other samples that could be informative for patients with cancer. Cancer genetic testing is a series of tests that finds specific changes in cancer cells and normal cells in the body. Researchers may request to access these data as they explore how to better prevent, screen, or treat cancer. This study is also being done to create a biobank (library) of... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/19/2025
Locations: Mayo Clinic in Arizona, Scottsdale, Arizona +2 locations
Conditions: Cancer, Cancer Gene Mutation, PAN Gene Mutation, Hematopoietic and Lymphoid System Neoplasm, Malignant Solid Neoplasm
Patient Descriptors of Cancer-Related Fatigue: a Mixed Methods Pilot Study of Cancer Survivors
Recruiting
The purpose of this research study is to better understand how cancer-related fatigue affects patients and how it's discussed with providers. This information will be used to develop an educational resource (visual aid poster) that could help individuals and their providers talk about cancer-related fatigue and which may help individuals better manage this symptom.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/19/2025
Locations: Levine Cancer Institute, Charlotte, North Carolina +1 locations
Conditions: Cancer, Fatigue
Isa-Rd for Frail and/or Much Older Patients With Newly Diagnosed Multiple Myeloma
Recruiting
This research study is investigating the safety and effectiveness of using combination of isatuximab, lenalidomide and dexamethasone for the treatment of newly diagnosed multiple myeloma (MM). The study team will use lower doses than is currently standard for these drugs. Lower doses will be used to avoid or possibly reduce any unwanted side effects commonly associated with these drugs. Using lower doses of the combination isatuximab, lenalidomide and dexamethasone, has not been approved by the... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/18/2025
Locations: University of North Carolina at Chapel Hill, Lineberger Comprehensive Cancer Center, Chapel Hill, North Carolina +2 locations
Conditions: Multiple Myeloma, Cancer