There are currently 41 active clinical trials seeking participants for COPD research studies. The states with the highest number of trials for Autism participants are Florida, California, Texas and South Carolina.
The Effect of Interval Exercise on Functional Outcomes in Veterans With COPD and OSA
Recruiting
The term "Overlap Syndrome" (OS) is used to describe the presence of both chronic obstructive pulmonary disease (COPD) and obstructive sleep apnea (OSA) in a single patient. Due to premature aging, patients with OS are prone to developing functional decline up to 20 years earlier than the general population. The International Classification of Functioning, Disability and Health (ICF) evaluates functional status in chronic pulmonary disease globally in 5 domains. The investigators propose to stud... Read More
Gender:
All
Ages:
All
Trial Updated:
04/18/2023
Locations: Salem VA Medical Center, Salem, VA, Salem, Virginia
Conditions: COPD, OSA
Impairments That Affect Correct Inhaler Use in COPD
Recruiting
INHALE is a one-year, multi-site observational research study funded by Viatris, with two aims: Determine the prevalence of both cognitive impairment and impaired manual dexterity in stable out-patients with chronic obstructive pulmonary disease (COPD). Assess the relationship of cognitive impairment and impaired manual dexterity with patient errors using current pMDIs, SMIs and/or DPIs.
Gender:
All
Ages:
Between 60 years and 90 years
Trial Updated:
03/21/2024
Locations: University of Alabama at Birmingham - Lung Health Center, Birmingham, Alabama +3 locations
Conditions: COPD
The Effects of Positive Airway Pressure on the Mucolytic Effects of NAC (TEAM)
Recruiting
The goal of this clinical trial is to determine if positive pressure during inspiration will improve penetration of aerosolized N-Acetylcysteine (NAC) into airway mucus plugs in the lungs of patients with asthma or Chronic Obstructive Pulmonary Disease (COPD). The main questions it aims to answer are: Does delivery of aerosolized NAC with positive inspiratory pressure have a greater effect on mucus plug burden in the lungs than delivery of NAC without positive pressure. Does delivery of aeroso... Read More
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
03/15/2024
Locations: UCSF Airway Clinical Research Center, San Francisco, California
Conditions: Asthma, COPD
Nurse Coach-Led Early Palliative Care for Older Adults With COPD and Their Care Partners: The Project EPIC Pilot RCT
Recruiting
Chronic obstructive pulmonary disease (COPD) is the third leading cause of death in older Americans. COPD increases in frequency with age, and older adults with COPD often have significant unmet geriatrics-palliative care needs that results in reduced quality of life, high healthcare utilization, and care at the end of life that does not align with the values and wishes of patients and their care partners. Older adults with COPD could benefit from proactive geriatrics-palliative care before the... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
03/11/2024
Locations: University of Alabama at Birmingham, Birmingham, Alabama
Conditions: COPD
Heat Waves and the Elderly With COPD
Recruiting
The purpose of this study is to investigate thermoregulatory responses in older individuals with COPD.
Gender:
All
Ages:
65 years and above
Trial Updated:
03/04/2024
Locations: Texas Health Presbyterian Hospital Dallas, Dallas, Texas
Conditions: COPD, Aging, Hyperthermia
Telehealth and Onsite Maintenance Exercise in COPD
Recruiting
The goal of this pilot clinical trial is to compare telehealth and onsite supervised maintenance exercise program for adults with COPD. The specific aims of the study are: To compare 8-week supervised maintenance program delivered onsite and via tele-rehab with no maintenance for patients with COPD following discharge from traditional exercise or physical therapy or onsite outpatient rehabilitation programs on clinical outcomes (dyspnea, exercise capacity, physical function, physical activity,... Read More
Gender:
All
Ages:
40 years and above
Trial Updated:
03/04/2024
Locations: MGH Institute of Health Professions, Charlestown, Massachusetts
Conditions: Copd, COPD Exacerbation, COPD Bronchitis
The Reducing REVISITS Study: A Cluster RCT
Recruiting
This type II hybrid effectiveness-implementation trial will concurrently study the comparative effectiveness of virtual vs. in-person COPD care transition programs implemented via virtual mentored implementation approaches with and without co-design methods. The investigators will enroll up to 24 randomized sites (with a goal minimum of 16 sites) to: Deliver the COPD programs implemented via mentored support in collaboration with SHM Center for Quality Improvement. Compare the effectiveness an... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
02/23/2024
Locations: University of Chicago, Chicago, Illinois
Conditions: COPD, COPD Exacerbation Acute
4D Medical X-ray Velocimetry for Bronchoscopic Lung Volume Reduction Targeting
Recruiting
This study will investigate the utility of 4D Medical's X-ray Velocimetry (XV) imaging analysis software for the detection of hyperinflation, and compare endobronchial valve placement outcomes with predictive indices obtained utilizing this technique.
Gender:
All
Ages:
18 years and above
Trial Updated:
01/31/2024
Locations: Vanderbilt University Medical Center, Nashville, Tennessee
Conditions: Copd, Emphysema, Hyperinflation
A Study to Evaluate Safety and Efficacy of BOTOX in Adults With Moderate COPD
Recruiting
The aim of this clinical trial to determine the safety and effectiveness of treating the COPD symptoms with subcutaneous BOTOX injections in participants with moderate COPD.
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
01/29/2024
Locations: Tranquil Clinical Research, Webster, Texas
Conditions: COPD
The Effect of a Technology-Mediated Integrated Walking and Tai Chi Intervention on Physical Function in Veterans With COPD and Chronic Musculoskeletal Pain
Recruiting
Persons with COPD benefit from being physically active, but they are often limited by chronic musculoskeletal pain. This project will determine whether a non-pharmacologic, integrated, technology-mediated walking and Tai Chi mindfulness intervention can improve physical function in Veterans with COPD and chronic musculoskeletal pain. The proposed research addresses VA Rehabilitation R&D Service's high priority area of improving health-related quality of life by reducing disease burden and maximi... Read More
Gender:
All
Ages:
Between 40 years and 100 years
Trial Updated:
01/25/2024
Locations: VA Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, MA, Boston, Massachusetts
Conditions: COPD, Chronic Musculoskeletal Pain
Pulmonary Hypertension SOLAR
Recruiting
The main goal of this study is to develop a noninvasive signature for pulmonary vascular remodeling in Group 3 PH patients, using hyperpolarized 129Xe magnetic resonance imaging (129Xe MRI). Such a signature may identify Group 3 PH responders to PAH-specific therapies. PAH's unique 129Xe MRI signature has been shown in previous studies. Past studies have lacked a pathologic "ground truth" correlate of these signatures, which could be provided by comparing them with the pathology of lung explant... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
01/16/2024
Locations: Duke University Medical Center, Durham, North Carolina
Conditions: Interstitial Lung Disease, COPD, Pulmonary Arterial Hypertension
myAirvo 3 (High Flow Nasal Therapy; HFNT) for COPD Patients in the Home
Recruiting
Parallel-group, prospective, randomized, controlled phase III trial of home High flow Nasal Therapy (HFNT) via myAirvo 3 plus usual COPD medical care vs. usual COPD medical care, for at least 1 year and up to two years in 642 GOLD Grade D, Stages II-IV patients with moderate to very severe COPD at risk for moderate and severe exacerbations with a prior history of severe exacerbation requiring hospitalization within the past 6 weeks.
Gender:
All
Ages:
30 years and above
Trial Updated:
01/08/2024
Locations: Destiny Research, Palmetto Bay, Florida +11 locations
Conditions: COPD