There are currently 39 active clinical trials seeking participants for COPD research studies. The states with the highest number of trials for Autism participants are Florida, California, Texas and South Carolina.
The Effect of Interval Exercise on Functional Outcomes in Veterans With COPD and OSA
Recruiting
The term "Overlap Syndrome" (OS) is used to describe the presence of both chronic obstructive pulmonary disease (COPD) and obstructive sleep apnea (OSA) in a single patient. Due to premature aging, patients with OS are prone to developing functional decline up to 20 years earlier than the general population. The International Classification of Functioning, Disability and Health (ICF) evaluates functional status in chronic pulmonary disease globally in 5 domains. The investigators propose to stud... Read More
Gender:
All
Ages:
All
Trial Updated:
04/18/2023
Locations: Salem VA Medical Center, Salem, VA, Salem, Virginia
Conditions: COPD, OSA
Impairments That Affect Correct Inhaler Use in COPD
Recruiting
INHALE is a one-year, multi-site observational research study funded by Viatris, with two aims: Determine the prevalence of both cognitive impairment and impaired manual dexterity in stable out-patients with chronic obstructive pulmonary disease (COPD). Assess the relationship of cognitive impairment and impaired manual dexterity with patient errors using current pMDIs, SMIs and/or DPIs.
Gender:
All
Ages:
Between 60 years and 90 years
Trial Updated:
02/07/2024
Locations: Valley Regional Hospital, Claremont, New Hampshire
Conditions: COPD
The Effects of Positive Airway Pressure on the Mucolytic Effects of NAC (TEAM)
Recruiting
The goal of this clinical trial is to determine if positive pressure during inspiration will improve penetration of aerosolized N-Acetylcysteine (NAC) into airway mucus plugs in the lungs of patients with asthma or Chronic Obstructive Pulmonary Disease (COPD). The main questions it aims to answer are: Does delivery of aerosolized NAC with positive inspiratory pressure have a greater effect on mucus plug burden in the lungs than delivery of NAC without positive pressure. Does delivery of aeroso... Read More
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
02/07/2024
Locations: UCSF Airway Clinical Research Center, San Francisco, California
Conditions: Asthma, COPD
4D Medical X-ray Velocimetry for Bronchoscopic Lung Volume Reduction Targeting
Recruiting
This study will investigate the utility of 4D Medical's X-ray Velocimetry (XV) imaging analysis software for the detection of hyperinflation, and compare endobronchial valve placement outcomes with predictive indices obtained utilizing this technique.
Gender:
All
Ages:
18 years and above
Trial Updated:
01/31/2024
Locations: Vanderbilt University Medical Center, Nashville, Tennessee
Conditions: Copd, Emphysema, Hyperinflation
A Study to Evaluate Safety and Efficacy of BOTOX in Adults With Moderate COPD
Recruiting
The aim of this clinical trial to determine the safety and effectiveness of treating the COPD symptoms with subcutaneous BOTOX injections in participants with moderate COPD.
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
01/29/2024
Locations: Tranquil Clinical Research, Webster, Texas
Conditions: COPD
The Effect of a Technology-Mediated Integrated Walking and Tai Chi Intervention on Physical Function in Veterans With COPD and Chronic Musculoskeletal Pain
Recruiting
Persons with COPD benefit from being physically active, but they are often limited by chronic musculoskeletal pain. This project will determine whether a non-pharmacologic, integrated, technology-mediated walking and Tai Chi mindfulness intervention can improve physical function in Veterans with COPD and chronic musculoskeletal pain. The proposed research addresses VA Rehabilitation R&D Service's high priority area of improving health-related quality of life by reducing disease burden and maximi... Read More
Gender:
All
Ages:
Between 40 years and 100 years
Trial Updated:
01/25/2024
Locations: VA Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, MA, Boston, Massachusetts
Conditions: COPD, Chronic Musculoskeletal Pain
Pulmonary Hypertension SOLAR
Recruiting
The main goal of this study is to develop a noninvasive signature for pulmonary vascular remodeling in Group 3 PH patients, using hyperpolarized 129Xe magnetic resonance imaging (129Xe MRI). Such a signature may identify Group 3 PH responders to PAH-specific therapies. PAH's unique 129Xe MRI signature has been shown in previous studies. Past studies have lacked a pathologic "ground truth" correlate of these signatures, which could be provided by comparing them with the pathology of lung explant... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
01/16/2024
Locations: Duke University Medical Center, Durham, North Carolina
Conditions: Interstitial Lung Disease, COPD, Pulmonary Arterial Hypertension
myAirvo 3 (High Flow Nasal Therapy; HFNT) for COPD Patients in the Home
Recruiting
Parallel-group, prospective, randomized, controlled phase III trial of home High flow Nasal Therapy (HFNT) via myAirvo 3 plus usual COPD medical care vs. usual COPD medical care, for at least 1 year and up to two years in 642 GOLD Grade D, Stages II-IV patients with moderate to very severe COPD at risk for moderate and severe exacerbations with a prior history of severe exacerbation requiring hospitalization within the past 6 weeks.
Gender:
All
Ages:
30 years and above
Trial Updated:
01/08/2024
Locations: Destiny Research, Palmetto Bay, Florida +11 locations
Conditions: COPD
COPD Access to Pulmonary Rehabilitation Intervention
Recruiting
Persons with COPD have significant functional disability but cannot access rehabilitative treatment at hospital-based conventional pulmonary rehabilitation (PR) programs. This project will determine whether an Internet-mediated, pedometer-based walking program can increase physical activity in persons with COPD who qualify for but cannot access PR, compared to usual care. This proposal has high potential to deliver an immediate solution to a pressing clinical need. The proposed research addresse... Read More
Gender:
All
Ages:
40 years and above
Trial Updated:
12/29/2023
Locations: VA Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, MA, Boston, Massachusetts
Conditions: COPD
Pragmatic Assessment of the NuvoAir Clinical Service in the Management of Patients With Chronic Obstructive Pulmonary Disease
Recruiting
This is a 12 month study of up to 500 people with COPD to determine if the NuvoAir clinical service leads to lower rates of severe COPD exacerbations, hospitalizations, emergency room visits, and total cost of care compared to a similar group that doesn't receive care from the NuvoAir clinical service.
Gender:
All
Ages:
30 years and above
Trial Updated:
12/13/2023
Locations: Marshfield Clinic Research Institute, Marshfield, Wisconsin
Conditions: COPD, Comorbidities and Coexisting Conditions
Impact of Positive Airway Pressure Therapy on Clinical Outcomes in Older Veterans With Chronic Obstructive Pulmonary Disease and Comorbid Obstructive Sleep Apnea (Overlap Syndrome)
Recruiting
Obstructive sleep apnea (OSA) and Chronic Obstructive Pulmonary Disease (COPD) are highly prevalent chronic respiratory diseases in the Veteran population. OSA co-occurring with COPD, known as Overlap Syndrome (OVS), is a complex chronic medical condition associated with grave consequences. OVS is highly prevalent in Veterans. Veterans with OVS may be at increased risk for cognitive deficits, poor sleep quality as well as a reduced quality of life (QoL). The overall objective is to study the eff... Read More
Gender:
All
Ages:
60 years and above
Trial Updated:
12/13/2023
Locations: VA Ann Arbor Healthcare System, Ann Arbor, MI, Ann Arbor, Michigan +1 locations
Conditions: Sleep Apnea Syndrome, Obstructive Sleep Apnea, COPD, Overlap Syndrome, Quality of Life, Neurocognitive Function, Sleepiness, Elderly, Positive Airway Pressure
Anti-Platelets in Chronic Obstructive Pulmonary Disease
Recruiting
This is a 6 week crossover study in former smokers with and without COPD to evaluate whether 2 weeks of dual antiplatelet therapy (aspirin 81mg and clopidogrel 75mg) improves pulmonary perfusion (i.e. blood flow in the lungs measured on a contrast CT scan) compared to placebo.
Gender:
All
Ages:
Between 50 years and 75 years
Trial Updated:
12/08/2023
Locations: Brigham and Women's Hospital, Boston, Massachusetts
Conditions: COPD, Emphysema, Emphysema or COPD