There are currently 41 active clinical trials seeking participants for COPD research studies. The states with the highest number of trials for Autism participants are Florida, California, Texas and South Carolina.
A Study to Evaluate Safety and Efficacy of BOTOX in Adults With Moderate COPD
NCT06003049
Recruiting
The aim of this clinical trial to determine the safety and effectiveness of treating the COPD symptoms with subcutaneous BOTOX injections in participants with moderate COPD.
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
01/29/2024
Locations: Tranquil Clinical Research, Webster, Texas
Conditions: COPD
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The Effect of a Technology-Mediated Integrated Walking and Tai Chi Intervention on Physical Function in Veterans With COPD and Chronic Musculoskeletal Pain
NCT05701982
Recruiting
Persons with COPD benefit from being physically active, but they are often limited by chronic musculoskeletal pain. This project will determine whether a non-pharmacologic, integrated, technology-mediated walking and Tai Chi mindfulness intervention can improve physical function in Veterans with COPD and chronic musculoskeletal pain. The proposed research addresses VA Rehabilitation R&D Service's high priority area of improving health-related quality of life by reducing disease burden and maximi... Read More
Gender:
All
Ages:
Between 40 years and 100 years
Trial Updated:
01/25/2024
Locations: VA Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, MA, Boston, Massachusetts
Conditions: COPD, Chronic Musculoskeletal Pain
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Pulmonary Hypertension SOLAR
NCT04778046
Recruiting
The main goal of this study is to develop a noninvasive signature for pulmonary vascular remodeling in Group 3 PH patients, using hyperpolarized 129Xe magnetic resonance imaging (129Xe MRI). Such a signature may identify Group 3 PH responders to PAH-specific therapies. PAH's unique 129Xe MRI signature has been shown in previous studies. Past studies have lacked a pathologic "ground truth" correlate of these signatures, which could be provided by comparing them with the pathology of lung explant... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
01/16/2024
Locations: Duke University Medical Center, Durham, North Carolina
Conditions: Interstitial Lung Disease, COPD, Pulmonary Arterial Hypertension
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myAirvo 3 (High Flow Nasal Therapy; HFNT) for COPD Patients in the Home
NCT05204888
Recruiting
Parallel-group, prospective, randomized, controlled phase III trial of home High flow Nasal Therapy (HFNT) via myAirvo 3 plus usual COPD medical care vs. usual COPD medical care, for at least 1 year and up to two years in 642 GOLD Grade D, Stages II-IV patients with moderate to very severe COPD at risk for moderate and severe exacerbations with a prior history of severe exacerbation requiring hospitalization within the past 6 weeks.
Gender:
All
Ages:
30 years and above
Trial Updated:
01/08/2024
Locations: Destiny Research, Palmetto Bay, Florida +11 locations
Conditions: COPD
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COPD Access to Pulmonary Rehabilitation Intervention
NCT03794921
Recruiting
Persons with COPD have significant functional disability but cannot access rehabilitative treatment at hospital-based conventional pulmonary rehabilitation (PR) programs. This project will determine whether an Internet-mediated, pedometer-based walking program can increase physical activity in persons with COPD who qualify for but cannot access PR, compared to usual care. This proposal has high potential to deliver an immediate solution to a pressing clinical need. The proposed research addresse... Read More
Gender:
All
Ages:
40 years and above
Trial Updated:
12/29/2023
Locations: VA Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, MA, Boston, Massachusetts
Conditions: COPD
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Pragmatic Assessment of the NuvoAir Clinical Service in the Management of Patients With Chronic Obstructive Pulmonary Disease
NCT05955482
Recruiting
This is a 12 month study of up to 500 people with COPD to determine if the NuvoAir clinical service leads to lower rates of severe COPD exacerbations, hospitalizations, emergency room visits, and total cost of care compared to a similar group that doesn't receive care from the NuvoAir clinical service.
Gender:
All
Ages:
30 years and above
Trial Updated:
12/13/2023
Locations: Marshfield Clinic Research Institute, Marshfield, Wisconsin
Conditions: COPD, Comorbidities and Coexisting Conditions
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Impact of Positive Airway Pressure Therapy on Clinical Outcomes in Older Veterans With Chronic Obstructive Pulmonary Disease and Comorbid Obstructive Sleep Apnea (Overlap Syndrome)
NCT04179981
Recruiting
Obstructive sleep apnea (OSA) and Chronic Obstructive Pulmonary Disease (COPD) are highly prevalent chronic respiratory diseases in the Veteran population. OSA co-occurring with COPD, known as Overlap Syndrome (OVS), is a complex chronic medical condition associated with grave consequences. OVS is highly prevalent in Veterans. Veterans with OVS may be at increased risk for cognitive deficits, poor sleep quality as well as a reduced quality of life (QoL). The overall objective is to study the eff... Read More
Gender:
All
Ages:
60 years and above
Trial Updated:
12/13/2023
Locations: VA Ann Arbor Healthcare System, Ann Arbor, MI, Ann Arbor, Michigan +1 locations
Conditions: Sleep Apnea Syndrome, Obstructive Sleep Apnea, COPD, Overlap Syndrome, Quality of Life, Neurocognitive Function, Sleepiness, Elderly, Positive Airway Pressure
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Anti-Platelets in Chronic Obstructive Pulmonary Disease
NCT05567562
Recruiting
This is a 6 week crossover study in former smokers with and without COPD to evaluate whether 2 weeks of dual antiplatelet therapy (aspirin 81mg and clopidogrel 75mg) improves pulmonary perfusion (i.e. blood flow in the lungs measured on a contrast CT scan) compared to placebo.
Gender:
All
Ages:
Between 50 years and 75 years
Trial Updated:
12/08/2023
Locations: Brigham and Women's Hospital, Boston, Massachusetts
Conditions: COPD, Emphysema, Emphysema or COPD
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Acupuncture to Enhance for Pulmonary Rehab
NCT04947800
Recruiting
The investigator is investigating if acupuncture may improve pulmonary function, exercise tolerance, stress and modulate the inflammatory effects of chronic obstructive pulmonary disease (COPD). The investigator would like to measure the effect of the combination of acupuncture with standard pulmonary rehab in patients with COPD.
Gender:
All
Ages:
18 years and above
Trial Updated:
12/07/2023
Locations: Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire
Conditions: COPD
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High Resolution Micro OCT Imaging
NCT03256773
Recruiting
The purpose of this study is to learn about using the imaging to make images of the lungs and nose with the long-term goal of the research leading to potential treatments and new therapies for patients with cystic fibrosis.
Gender:
All
Ages:
14 years and above
Trial Updated:
12/06/2023
Locations: University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Cystic Fibrosis, COPD, PCD - Primary Ciliary Dyskinesia, Covid19, Sinusitis
Register for Updates
Revefenacin in Acute Respiratory Insufficiency in COPD
NCT04315558
Recruiting
RARICO is a pragmatic, randomized, controlled, double-blinded, multi-center trial evaluating the safety and feasibility of nebulized revefenacin in comparison to nebulized ipratropium in patients with COPD and acute respiratory failure requiring invasive mechanical ventilation.
Gender:
All
Ages:
40 years and above
Trial Updated:
12/01/2023
Locations: Ronald Reagan Medical Center at UCLA, Los Angeles, California +1 locations
Conditions: COPD, Acute Respiratory Failure
Register for Updates
Identifying Right Ventricular Dysfunction in COPD Through Right Heart Catheterization, Imaging and Exercise
NCT05896579
Recruiting
This study plans to learn more about heart function among individuals with chronic obstructive pulmonary disease (COPD). In particular, the investigators want to understand the different patterns of right ventricular response to pulmonary hypertension (high pressure in the lungs) during rest and exercise. By identifying patterns of right ventricular dysfunction, this study will help identify better treatments for patients with COPD in the future.
Gender:
All
Ages:
Between 40 years and 80 years
Trial Updated:
11/29/2023
Locations: University of Colorado Anschutz Medical Campus, Aurora, Colorado
Conditions: COPD, Pulmonary Hypertension, Right Ventricular Dysfunction
Register for Updates