There are currently 30 active clinical trials seeking participants for Endometriosis research studies. The states with the highest number of trials for Endometriosis participants are Florida, Texas, California and Ohio.
Evaluation of Endometriosis With 18F-fluorofuranylnorprogesterone PET / MRI
NCT05480995
Recruiting
Purpose: The aim of this study is to assess the sensitivity and specificity of FFNP PET/MRI for diagnosis of endometriosis. Participants: A total of 24 participants will be recruited from individuals with clinically suspected endometriosis. Procedures (methods): This is a prospective, one arm, single center study of 24 subjects with clinically suspected endometriosis to demonstrate FFNP PET-MRI's clinical utility for diagnosis of endometriosis.
Gender:
Female
Ages:
Between 18 years and 55 years
Trial Updated:
02/15/2024
Locations: University of North Carolina at Chapel Hill, Chapel Hill, North Carolina
Conditions: Endometriosis
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Comparison of Proton or Intensity Modulated Radiation Therapy After Surgery for Endometrial or Cervical Cancer
NCT04567771
Recruiting
This early phase I trial compares the side effects between patients treated with proton radiation therapy versus intensity modulated radiation therapy after surgery for the treatment of endometrial or cervical cancer. Radiation therapy uses high energy protons or x-rays to kill tumor cells and shrink tumors. Using quality of life questionnaires and adverse event assessments may help doctors learn whether proton radiation therapy is associated with lower acute gastrointestinal toxicities at the e... Read More
Gender:
Female
Ages:
18 years and above
Trial Updated:
02/09/2024
Locations: Mayo Clinic in Arizona, Scottsdale, Arizona +2 locations
Conditions: Cervical Carcinoma, Endometrial Carcinoma, Endometriosis, Pelvic Inflammatory Disease
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Thromboxane Function in Women With Endometriosis
NCT05962034
Recruiting
The goal of this clinical trial is to compare neurovascular regulation in women with endometriosis and healthy women. The main questions it aims to answer are: Do women with endometriosis have greater blood pressure and pain responses to a stimulus than healthy women? Do women with endometriosis have greater platelet activity than healthy women? Participants will take aspirin and/or placebo and will: perform hand grip exercise and cold pressor tests undergo iontophoresis and blood draw Resea... Read More
Gender:
Female
Ages:
Between 18 years and 45 years
Trial Updated:
02/05/2024
Locations: Noll Laboratory, University Park, Pennsylvania
Conditions: Endometriosis
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Endometriosis and Microvascular Dysfunction; Simvastatin and Duavee
NCT05059626
Recruiting
Purpose: To determine the effects of SERM and simvastatin interventions on endothelial dysfunction in women with endometriosis. Hypothesis: Treatment with the SERM (bazedoxifene + conjugated estrogen) or with simvastatin will decrease systemic inflammation and improve specific measures of cardiovascular function including endothelium-dependent vasodilation.
Gender:
Female
Ages:
Between 18 years and 45 years
Trial Updated:
02/05/2024
Locations: The John B. Pierce Laboratory, New Haven, Connecticut
Conditions: Endometriosis
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Endometriosis and Microvascular Dysfunction: Role of Inflammation
NCT05069740
Recruiting
The purpose of this study is to better understand the underlying mechanisms associated with elevated cardiovascular disease risk in women with endometriosis, and to measure the effectiveness of emerging endometriosis treatments on outcomes specific to cardiovascular dysfunction. Epidemiologic data demonstrate a clear association between endometriosis, reproductive risk factors, inflammation and cardiovascular (CV) risk. Circulating factors, low-density lipoprotein (LDL) and oxidized LDL (oxLDL)... Read More
Gender:
Female
Ages:
Between 18 years and 45 years
Trial Updated:
02/05/2024
Locations: The Pennsylvania State University, University Park, Pennsylvania
Conditions: Endometriosis
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Use of TENS Unit in the Management of Endometriosis Pain
NCT05348005
Recruiting
The purpose of this study is see if Transcutaneous Electrical Nerve Stimulator (TENS) units help decrease endometriosis flare pain. TENS units have a 510K and are intended for relief of pain associated with sore or aching muscles of the lower back, arms, or legs due to strain from exercise or normal household and work activities. Participants will complete surveys, record pain, medication use and bleeding in an online diary during endometriosis flare ups for 3 months without using the TENS unit... Read More
Gender:
Female
Ages:
Between 18 years and 45 years
Trial Updated:
12/19/2023
Locations: Penn State Health Milton S. Hershey Medical Center, Hershey, Pennsylvania
Conditions: Endometriosis, Pelvic Pain
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The Using Postoperative Ketamine and Exploring the Effect on Endometriosis Pain (UPKEEEP) Study
NCT05229653
Recruiting
This is a randomized, single blinded, placebo-controlled trial to study the effectiveness of a subanesthetic dose (0.6 mg/kg) of ketamine versus placebo (saline) on postoperative pain and pain on adult female chronic pelvic pain patients undergoing robotic removal of endometriosis. The objective of the study is to explore the effect of a sub anesthetic dose of ketamine (0.6 mg/kg) vs. saline control on postoperative pain and recovery in chronic pelvic pain patients who have undergone robotic rem... Read More
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
12/12/2023
Locations: NYU Langone Health, New York, New York
Conditions: Endometriosis, Post Operative Pain
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Nutritional Intervention for Endometriosis
NCT05175248
Recruiting
In a 12-week parallel study, women with a verified diagnosis of endometriosis will be randomly assigned to follow a low-fat plant-based diet or to stay on their usual diets for 12 weeks. Participants in both groups will be asked to make no changes to their exercise patterns for the study period. Changes in pain, quality of life, and inflammatory biomarkers from baseline to final will be the primary outcomes. Secondary outcomes will include changes in body weight, blood lipids, gut microbiome com... Read More
Gender:
Female
Ages:
Between 18 years and 45 years
Trial Updated:
11/02/2023
Locations: Physicians Committee for Responsible Medicine, Washington, District of Columbia
Conditions: Endometriosis
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A Study to Assess the Efficacy and Safety of HMI-115 in Subjects With Endometriosis-Associated Pain
NCT05101317
Recruiting
This study is designed to evaluate the safety and efficacy of HMI-115 compared to placebo over a 12 weeks period on subjects with moderate to severe endometriosis-associated pain.
Gender:
Female
Ages:
Between 18 years and 49 years
Trial Updated:
11/01/2023
Locations: Physicians' Research Options, LLC- Corner Canyon Clinic, Draper, Utah +4 locations
Conditions: Endometriosis
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Endometriosis Pain
NCT06101303
Recruiting
Aim 1. To determine the factors contributing to pain in patients with chronic pelvic pain with and without endometriosis Aim 2. To determine the changes following endometriosis lesion removal surgery in pain and sex hormone levels. Aim 3. To identify factors predicting clinical pain reduction after lesion removal surgery. Additional exploratory aims might compare subgroups of patients such as patients with vs. without endometriosis, with vs. without additional chronic pain syndromes, and with... Read More
Gender:
Female
Ages:
Between 12 years and 45 years
Trial Updated:
10/30/2023
Locations: Washington University School of Medicine, Saint Louis, Missouri
Conditions: Pelvic Pain, Endometriosis
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The Use of Low Dose Metronidazole to Decrease Postoperative Pain After Endometriosis Surgery
NCT04554693
Recruiting
The purpose of this study is to determine a difference in participant reported pain after endometriosis surgery in participants given oral metronidazole versus placebo.
Gender:
Female
Ages:
Between 18 years and 50 years
Trial Updated:
10/25/2023
Locations: University of Louisville Hospital, Louisville, Kentucky
Conditions: Endometriosis, Endometriosis-related Pain
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Endometriosis Group Care
NCT05622955
Recruiting
The goal of this clinical trial is to test the effectiveness of the Peer Empowered Endometriosis Pain Support (PEEPS) program in people living with endometriosis-related pelvic pain. The main question[s] it aims to answer are: Is PEEPS effective at decreasing pain interference and improving patient-reported quality of life outcomes? What are the barriers and facilitators to PEEPS implementation? Participants will engage in eight weekly 2-hour sessions led by an endometriosis specialist, pain ps... Read More
Gender:
Female
Ages:
Between 18 years and 48 years
Trial Updated:
10/24/2023
Locations: Washington University in St. Louis, Saint Louis, Missouri
Conditions: Endometriosis, Pelvic Pain
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