There are currently 28 active clinical trials seeking participants for Endometriosis research studies. The states with the highest number of trials for Autism participants are Florida, Texas, California and Ohio.
Use of TENS Unit in the Management of Endometriosis Pain
NCT05348005
Recruiting
The purpose of this study is see if Transcutaneous Electrical Nerve Stimulator (TENS) units help decrease endometriosis flare pain. TENS units have a 510K and are intended for relief of pain associated with sore or aching muscles of the lower back, arms, or legs due to strain from exercise or normal household and work activities. Participants will complete surveys, record pain, medication use and bleeding in an online diary during endometriosis flare ups for 3 months without using the TENS unit... Read More
Gender:
Female
Ages:
Between 18 years and 45 years
Trial Updated:
12/19/2023
Locations: Penn State Health Milton S. Hershey Medical Center, Hershey, Pennsylvania
Conditions: Endometriosis, Pelvic Pain
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The Using Postoperative Ketamine and Exploring the Effect on Endometriosis Pain (UPKEEEP) Study
NCT05229653
Recruiting
This is a randomized, single blinded, placebo-controlled trial to study the effectiveness of a subanesthetic dose (0.6 mg/kg) of ketamine versus placebo (saline) on postoperative pain and pain on adult female chronic pelvic pain patients undergoing robotic removal of endometriosis. The objective of the study is to explore the effect of a sub anesthetic dose of ketamine (0.6 mg/kg) vs. saline control on postoperative pain and recovery in chronic pelvic pain patients who have undergone robotic rem... Read More
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
12/12/2023
Locations: NYU Langone Health, New York, New York
Conditions: Endometriosis, Post Operative Pain
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Nutritional Intervention for Endometriosis
NCT05175248
Recruiting
In a 12-week parallel study, women with a verified diagnosis of endometriosis will be randomly assigned to follow a low-fat plant-based diet or to stay on their usual diets for 12 weeks. Participants in both groups will be asked to make no changes to their exercise patterns for the study period. Changes in pain, quality of life, and inflammatory biomarkers from baseline to final will be the primary outcomes. Secondary outcomes will include changes in body weight, blood lipids, gut microbiome com... Read More
Gender:
Female
Ages:
Between 18 years and 45 years
Trial Updated:
11/02/2023
Locations: Physicians Committee for Responsible Medicine, Washington, District of Columbia
Conditions: Endometriosis
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A Study to Assess the Efficacy and Safety of HMI-115 in Subjects With Endometriosis-Associated Pain
NCT05101317
Recruiting
This study is designed to evaluate the safety and efficacy of HMI-115 compared to placebo over a 12 weeks period on subjects with moderate to severe endometriosis-associated pain.
Gender:
Female
Ages:
Between 18 years and 49 years
Trial Updated:
11/01/2023
Locations: Physicians' Research Options, LLC- Corner Canyon Clinic, Draper, Utah +4 locations
Conditions: Endometriosis
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Endometriosis Pain
NCT06101303
Recruiting
Aim 1. To determine the factors contributing to pain in patients with chronic pelvic pain with and without endometriosis Aim 2. To determine the changes following endometriosis lesion removal surgery in pain and sex hormone levels. Aim 3. To identify factors predicting clinical pain reduction after lesion removal surgery. Additional exploratory aims might compare subgroups of patients such as patients with vs. without endometriosis, with vs. without additional chronic pain syndromes, and with... Read More
Gender:
Female
Ages:
Between 12 years and 45 years
Trial Updated:
10/30/2023
Locations: Washington University School of Medicine, Saint Louis, Missouri
Conditions: Pelvic Pain, Endometriosis
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The Use of Low Dose Metronidazole to Decrease Postoperative Pain After Endometriosis Surgery
NCT04554693
Recruiting
The purpose of this study is to determine a difference in participant reported pain after endometriosis surgery in participants given oral metronidazole versus placebo.
Gender:
Female
Ages:
Between 18 years and 50 years
Trial Updated:
10/25/2023
Locations: University of Louisville Hospital, Louisville, Kentucky
Conditions: Endometriosis, Endometriosis-related Pain
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Endometriosis Group Care
NCT05622955
Recruiting
The goal of this clinical trial is to test the effectiveness of the Peer Empowered Endometriosis Pain Support (PEEPS) program in people living with endometriosis-related pelvic pain. The main question[s] it aims to answer are: Is PEEPS effective at decreasing pain interference and improving patient-reported quality of life outcomes? What are the barriers and facilitators to PEEPS implementation? Participants will engage in eight weekly 2-hour sessions led by an endometriosis specialist, pain ps... Read More
Gender:
Female
Ages:
Between 18 years and 48 years
Trial Updated:
10/24/2023
Locations: Washington University in St. Louis, Saint Louis, Missouri
Conditions: Endometriosis, Pelvic Pain
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Cannabidiol and Management of Endometriosis Pain
NCT04527003
Recruiting
The investigators are looking to conduct a study looking at the effects of cannabidiol (CBD) in patients with endometriosis. It is believed that CBD will improve both pain and quality of life. The study will last a total of 12 weeks and involve several onsite visits in addition to daily pain assessments.
Gender:
Female
Ages:
Between 18 years and 45 years
Trial Updated:
10/10/2023
Locations: Penn State Health Milton S. Hershey Medical Center, Hershey, Pennsylvania
Conditions: Endometriosis, CBD, Pelvic Pain
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Transvaginal Low-level Laser Therapy to Improve Pelvic Pain and Sexual Function in Patients With Endometriosis.
NCT05540353
Recruiting
Dyspareunia is defined as pain with penetrative sexual intercourse. Women with endometriosis have a nine-fold increased risk of dyspareunia, when compared to the general female population. A prospective single-blinded randomized controlled trial will be performed evaluating the change in pelvic pain and sexual satisfaction scores from baseline to 6 weeks after treatment with transvaginal photobiomodulation therapy or sham therapy. Treatment will involve 9 planned treatment sessions over 3-4 wee... Read More
Gender:
Female
Ages:
18 years and above
Trial Updated:
09/01/2023
Locations: MedStar Washington Hospital Center, Washington, District of Columbia +5 locations
Conditions: Endometriosis, Dyspareunia, Pelvic Pain
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Cardiovascular Disease Risk in Women With Endometriosis
NCT03746535
Recruiting
To test the hypothesis that estrogen suppression impairs endothelial dysfunction in endometriosis.
Gender:
Female
Ages:
Between 18 years and 45 years
Trial Updated:
08/16/2023
Locations: John B Pierce Laboratory, New Haven, Connecticut
Conditions: Endometriosis
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Cancer Driving Mutations in Endometriosis Lesions and Development of Progesterone Resistance
NCT03756480
Recruiting
This study will test the hypothesis that the molecular changes present in ectopic endometriosis lesions correlate with progesterone-resistant disease (using the criteria defined in this study) and are present in matched eutopic endometrium.
Gender:
Female
Ages:
Between 18 years and 45 years
Trial Updated:
08/07/2023
Locations: Yale School of Medicine, New Haven, Connecticut +2 locations
Conditions: Endometriosis, Endometrial Diseases
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Cabergoline for the Treatment of Chronic Pain Due to Endometriosis
NCT03928288
Recruiting
Endometriosis is dependent on angiogenesis (the sprouting of new blood vessels) for its growth and maintenance, but the side effects of currently approved angiogenesis inhibitors make these agents inappropriate for use in reproductive-age patients. This obstacle will be overcome by performing a randomized, double blind clinical trial aimed at repurposing an existing drug, cabergoline, as a safe, alternative angiogenesis inhibitor for adolescents and young women with endometriosis. This trial pro... Read More
Gender:
Female
Ages:
Between 15 years and 40 years
Trial Updated:
07/31/2023
Locations: Beth Israel Deaconess Medical Center, Boston, Massachusetts +3 locations
Conditions: Endometriosis
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