There are currently 71 active clinical trials seeking participants for Type 1 Diabetes research studies. The states with the highest number of trials for Type 1 Diabetes participants are California, Texas, Florida and Colorado.
Post Market Registry for the Omnipod 5 System in Children and Adults With Type 1 Diabetes
NCT06144554
Recruiting
This is a decentralized observational clinical registry to collect real-world evidence related to the safety and effectiveness of the Omnipod 5 system in children and adults with Type 1 Diabetes.
Gender:
ALL
Ages:
2 years and above
Trial Updated:
05/14/2025
Locations: Circuit Clinical, Buffalo, New York
Conditions: Type 1 Diabetes
Register for Updates
GLP-1Ra Impact on Metabolic Outcomes in Stage 2 T1DM While Receiving Teplizumab
NCT06338553
Recruiting
The goal of this study is to determine how a drug class called glucagon-like peptide-1 receptor agonists (GLP-1Ra) affects people during an early stage of Type 1 Diabetes undergoing clinical teplizumab treatment. This study involves giving participants a liquid meal under different conditions and observing how their bodies respond, focusing on blood sugar levels, insulin effectiveness, and blood vessel function. The meal tests are followed by two post-treatment tests, one with the GLP-1Ra drug a... Read More
Gender:
ALL
Ages:
Between 12 years and 50 years
Trial Updated:
05/13/2025
Locations: Vanderbilt University Medical Center, Nashville, Tennessee
Conditions: Type 1 Diabetes
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Improving Transition Care for Adolescents and Young Adults With Type 1 Diabetes
NCT05639088
Recruiting
The purpose of this research study is to evaluate a transition preparation program designed for adolescents and young adults (AYAs) with type 1 diabetes (T1D). This transition program will support AYAs as they prepare to transition from pediatric to adult endocrinology medical care and will also include a caregiver. Results from this study will inform clinical recommendations regarding self-management best practices for AYAs with T1D prior to transitioning to adult medical care.
Gender:
ALL
Ages:
16 years and above
Trial Updated:
05/12/2025
Locations: Virginia Commonwealth University, Richmond, Virginia
Conditions: Type 1 Diabetes
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Safety and Feasibility of a Machine-Learning Bolus Priming Added to Existing Control Algorithm
NCT06728059
Recruiting
A randomized crossover trial assessing glycemic control using Reinforcement Learning trained Bolus Priming System (BPS_RL) added to the the Automated Insulin Delivery as Adaptive NETwork (AIDANET algorithm) compared to the original AIDANET algorithm.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/12/2025
Locations: University of Virginia Center for Diabetes Technology, Charlottesville, Virginia
Conditions: Type 1 Diabetes
Register for Updates
Commercial or Open Source Closed Loop Impact on Pregnancy Study
NCT06654713
Recruiting
The goal of this observational study is to better understand what happens when pregnant people with type 1 diabetes (T1D) use automated insulin delivery (AID) systems. The main questions this study aims to answer are: * What are the maternal and neonatal outcomes with AID system use in pregnancy? * What are the glycemic outcomes with AID system use in pregnancy? * What are the behavioral and emotional outcomes with AID system use in pregnancy? Researchers will compare pregnant people who use c... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
05/06/2025
Locations: University of California, San Francisco, San Francisco, California
Conditions: Type 1 Diabetes, Pregnancy, High Risk, Insulin Dependent Diabetes, Pregnancy Related
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Denosumab for Type 1 Diabetes
NCT06524960
Recruiting
Type 1 diabetes (T1D) arises from abnormal immune cell-mediated injury to beta cells that make insulin. The injured beta cells can then no longer make the needed amount of insulin to stay healthy. However, in the early stages of T1D, some beta cells are still alive and functioning. Treatment to protect the beta cells against injury at this time could slow the progress of disease. Denosumab is an approved treatment for osteoporosis (a disease that thins and weakens the bones), high blood calcium... Read More
Gender:
ALL
Ages:
Between 18 years and 50 years
Trial Updated:
04/24/2025
Locations: University of Alabama at Birmingham, Birmingham, Alabama +2 locations
Conditions: Type 1 Diabetes
Register for Updates
BEAD-T1D: Building the Evidence to Address Disengagement in Type 1 Diabetes
NCT05488119
Recruiting
Youth with public insurance underutilize diabetes care, particularly diabetes technology which is associated with improvement in diabetes-specific outcomes. Thus, we urgently need studies to understand and increase diabetes technology utilization. This proposed research will (1) improve representation of youth in the literature, (2) address the gap in knowledge of barriers and promoters in youth, and (3) identify and address factors associated with diabetes technology uptake and utilization.
Gender:
ALL
Ages:
12 years and above
Trial Updated:
04/22/2025
Locations: Stanford University, Stanford, California
Conditions: Type 1 Diabetes
Register for Updates
Artificial Pancreas Technology to Reduce Glycemic Variability and Improve Cardiovascular Health in Type 1 Diabetes
NCT05653518
Recruiting
This study will examine the potential cardiovascular effect(s) of artificial pancreas (AP) technology in patients with type 1 diabetes. AP technology is a system of devices that closely mimics the glucose-regulating function of a healthy human pancreas. It includes an insulin pump and a continuous glucose monitor (CGM). In this study, the investigators will research whether improvements in blood glucose levels and blood glucose variability will in turn decrease biomarkers of inflammation and end... Read More
Gender:
ALL
Ages:
Between 18 years and 40 years
Trial Updated:
04/17/2025
Locations: University of Virginia Health System, Charlottesville, Virginia
Conditions: Type 1 Diabetes
Register for Updates
FAM (Follower, Action Plan, and Remote Monitoring) Intervention to Reduce Severe Hyperglycemia in Adults With Type 1 Diabetes Mellitus at Risk for Diabetic Ketoacidosis
NCT06114186
Recruiting
Diabetic ketoacidosis (DKA) results in significant morbidity and healthcare utilization and is the main contributor to loss of life expectancy in people with diabetes mellitus type 1 (T1DM) \<50 years old. This suggests the need to develop interventions to reduce DKA events. Innovative features of newer continuous glucose monitoring devices offer opportunities for novel strategies to reduce DKA. Designating a family member, friend, or caregiver as a Follower was associated with reduction in HbA1... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
04/16/2025
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Type 1 Diabetes
Register for Updates
Accessing Care, Clinical Trials and Screening for Underserved Children and Adults With Type 1 Diabetes (ACCESS-T1D)
NCT06908057
Recruiting
The purpose of this study is to identify people with T1D or celiac disease (CD) early in the course of their disease and to improve the methods of screening for these diseases.
Gender:
ALL
Ages:
2 years and above
Trial Updated:
04/02/2025
Locations: AdventHealth Translational Research Institute, Orlando, Florida
Conditions: Type 1 Diabetes, Celiac Disease
Register for Updates
TArgeting Type 1 Diabetes Using POLyamines (TADPOL)
NCT05594563
Recruiting
The goal of this clinical trial is to test a drug known as DFMO in people with Type 1 Diabetes (T1D). The main question\[s\] it aims to answer are: * Does it reduce stress on the cells that make insulin? * Does it preserve what is left of the body's insulin production? Participants will take either DFMO or a placebo (looks like DFMO but has no active ingredients) two times a day for about 6 months. Participants will have 6 in person visits and 1 phone visit over a period of 12 months. Visits wi... Read More
Gender:
ALL
Ages:
Between 4 years and 40 years
Trial Updated:
03/28/2025
Locations: Barbara Davis Center, Aurora, Colorado +5 locations
Conditions: Type 1 Diabetes
Register for Updates
Garmin PACT (Physical Activity Tracking in Type 1 Diabetes Using Garmin Vivosmart)
NCT05992350
Recruiting
The goal of this observational study is to test the Garmin Vivosmart in children and youth (8-21) with Type 1 Diabetes (T1D) and their parents. The main questions it aims to answer are: * Does the Garmin Vivosmart increase physical activity (PA)? * Does the Garmin Vivosmart improve T1D status Participants will: * Wear the Garmin Vivosmart (4 or higher) for a year * Complete surveys at the beginning, middle and end of participation asking about your T1D, T1D management, and PA * Parents of chi... Read More
Gender:
ALL
Ages:
Between 8 years and 21 years
Trial Updated:
03/27/2025
Locations: Children's Mercy, Kansas City, Missouri
Conditions: Type 1 Diabetes
Register for Updates