There are currently 72 active clinical trials seeking participants for Type 1 Diabetes research studies. The states with the highest number of trials for Type 1 Diabetes participants are California, Texas, Colorado and Florida.
IHERO Study: Insurance, Health and Economic Resources Online for Emerging Adults with Type 1 Diabetes
NCT06348160
Recruiting
This research study aims to test a financial and health insurance iHERO Toolkit for young adults with type1 diabetes. The iHERO Toolkit was developed over one year with the type 1 diabetes community, The Diabetes Link organization, and experts. Now, the investigators want to understand the impact of the iHERO Toolkit on diabetes self-management, financial stress, and health insurance literacy outcomes. The investigators are doing this study because it will help to better understand how to suppor... Read More
Gender:
ALL
Ages:
Between 18 years and 30 years
Trial Updated:
03/14/2025
Locations: Children's Hospital Los Angeles, Los Angeles, California +3 locations
Conditions: Type 1 Diabetes
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The Gut Microbiome in Type 1 Diabetes and Mechanism of Metformin Action
NCT05414409
Recruiting
Obesity prevalence in persons with T1D has increased, which further complicates management and risk for complications. The proposed study is relevant to public health because it helps us understand the role of the gut microbiome in disease pathophysiology in T1D youth with obesity as well as potential mechanisms to modify disease.
Gender:
ALL
Ages:
Between 11 years and 18 years
Trial Updated:
03/11/2025
Locations: Indiana University School of Medicine, Indianapolis, Indiana
Conditions: Type 1 Diabetes, Obesity
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Telemedicine-Delivered Unified Protocol for Cognitive Behavioral Therapy for Anxiety and Depression
NCT05734313
Recruiting
This project will evaluate a telemedicine-delivered, Unified Protocol for Cognitive-Behavioral Therapy (UP-CBT) enhanced with continuous glucose monitor (CGM) review to target anxiety and depressive symptoms and glycemic control in adults with type 1 diabetes.
Gender:
ALL
Ages:
Between 18 years and 64 years
Trial Updated:
03/10/2025
Locations: Boston University, Boston, Massachusetts +1 locations
Conditions: Diabetes, Type 1 Diabetes
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Reducing Diabetes Distress Using Cognitive Behavioral Therapy in Young Adults With Type 1 Diabetes
NCT05000021
Recruiting
This project proposes to use telemedicine-delivered cognitive-behavioral therapy (CBT) enhanced with continuous glucose monitor (CGM) review to target diabetes distress in adults with type 1 diabetes. The efficacy of CBT for diabetes distress (CBT-DD) will be tested in comparison to commercial FDA-approved CGM only in a randomized controlled clinical trial. The investigators' central hypothesis is that the addition of a CBT intervention that targets diabetes distress and self-management directly... Read More
Gender:
ALL
Ages:
Between 18 years and 64 years
Trial Updated:
03/10/2025
Locations: Albert Einstein College of Medicine, Bronx, New York +1 locations
Conditions: Type 1 Diabetes
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Expansion of the T1DES Pilot to a Public Hospital
NCT06494722
Recruiting
Diabetes distress has been identified as one of the largest contributors to the racial disparity in glycemic control that disproportionately burdens Black patients ages 18-30 years with type 1 diabetes (T1D). In order to combat this issue, this study assesses the feasibility of the culturally tailored intervention T1DES and evaluates the effect of the T1DES intervention on diabetes outcomes in a pilot randomized clinical trial among Black young adults with T1D.
Gender:
ALL
Ages:
Between 18 years and 30 years
Trial Updated:
03/07/2025
Locations: Grady Health System, Atlanta, Georgia
Conditions: Type 1 Diabetes
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Immune Function and the Progression to T1D
NCT05899439
Recruiting
To elucidate the mechanisms by which type 1 diabetes-associated genes; IFIH1, TYK2, IKZF4, as well as total genetic risk, impart functional immunoregulatory abnormalities that result in expansion of self-reactive adaptive immune cells, defective regulatory/effector mechanisms in T cells, inflammatory antigen presenting cells, and abnormal immune function in T cells and B cells.
Gender:
ALL
Ages:
Between 0 years and 100 years
Trial Updated:
03/04/2025
Locations: Kieran McGrail, Gainesville, Florida +2 locations
Conditions: Type 1 Diabetes
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MANATEE-T1D: Metformin and AutomaTEd Insulin Delivery System Effects on Renal Vascular Resistance, Insulin Sensitivity, and Cardiometabolic Function in Youth with Type 1 Diabetes
NCT05065372
Recruiting
Diabetic kidney disease and cardiovascular disease remain the leading causes of morbidity and mortality in people with type 1 diabetes and are exacerbated with longer duration of diabetes and time outside goal glycemic range. Yet, type 1 diabetes is a complex disease with pathophysiology that extends beyond beta-cell injury and insulin deficiency to include insulin resistance and renal vascular resistance, factors that accelerate cardiovascular disease risk. We have shown that metformin improved... Read More
Gender:
ALL
Ages:
Between 12 years and 25 years
Trial Updated:
03/04/2025
Locations: Children's Hospital Colorado, Aurora, Colorado +1 locations
Conditions: Type 1 Diabetes, Diabetic Kidney Disease, Cardiovascular Diseases, Endothelial Dysfunction, Insulin Sensitivity
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Cholesterol Lowering and Residual Risk in Diabetes, Type 1
NCT05641753
Recruiting
This is a prospective, interventional, cohort study, meaning that researchers will follow and observe a group of enrolled study participants over a period of time (one to two months) to gather information and record any developments of the outcomes in question. This study will recruit 125 participants with Type 1 Diabetes (T1D) to: 1. Analyze the effect of reducing the cholesterol levels in the blood on platelet function. (Platelets are small cells in the blood which help form blood clots to s... Read More
Gender:
ALL
Ages:
Between 18 years and 89 years
Trial Updated:
02/28/2025
Locations: New York VA Hospital, New York, New York +3 locations
Conditions: Type 1 Diabetes
Register for Updates
ACCESS 2: AI for pediatriC diabetiC Eye examS Study 2
NCT05463289
Recruiting
The purpose of this study is to determine if use of a nonmydriatic fundus camera using autonomous artificial intelligence software at the point of care increases the proportion of underserved youth with diabetes screened for diabetic retinopathy.
Gender:
ALL
Ages:
Between 8 years and 21 years
Trial Updated:
02/13/2025
Locations: Johns Hopkins Pediatric Diabetes Center, Baltimore, Maryland
Conditions: Type 1 Diabetes, Type 2 Diabetes, Cystic Fibrosis-related Diabetes
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PS230005 Control-IQ 1.5 Post-Approval Study
NCT06717451
Recruiting
This 522 post-market surveillance study is a single-arm, decentralized prospective observational cohort study designed to collect safety data on Control-IQ technology v1.5 in children with type 1 diabetes ages 2 to \<6 years old. Participants will use Control-IQ technology v1.5 for 12 months in the real-world setting.
Gender:
ALL
Ages:
Between 2 years and 5 years
Trial Updated:
01/31/2025
Locations: Tandem Diabetes Care, San Diego, California
Conditions: Type 1 Diabetes
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Type 1 Diabetes, Endothelin, and Skeletal Muscle Mitochondrial Dysfunction: The Role of Sirtuin-1
NCT04449198
Recruiting
The proposed study is designed to test the hypothesis that treatment of resveratrol for 12 weeks will improve both endothelin-B receptor (aim 1) and skeletal muscle mitochondrial function (aim 2) in people with type 1 diabetes.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/27/2025
Locations: Augusta University/Georgia Prevention Institute/ Laboratory of Integrative and Exercise Physiology, Augusta, Georgia
Conditions: Type 1 Diabetes
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Automated Insulin Delivery for Inpatients with Dysglycemia
NCT06418880
Recruiting
This randomized controlled trial will test the efficacy and safety of automated insulin delivery (AID) in hospitalized patients with diabetes (type 1 or type 2) requiring insulin therapy who are admitted to general medical/surgical floors. The main objectives of this study are: * To test the efficacy and safety of AID versus multiple daily insulin injections (MDI) + CGM in the inpatient setting * To determine differences in CGM-derived metrics between AID and MDI plus CGM in the hospital and e... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/27/2025
Locations: Stanford University School of Medicine, Stanford, California +2 locations
Conditions: Type 1 Diabetes, Type 2 Diabetes
Register for Updates