Indiana Clinical Trials

A listing of Indiana clinical trials actively recruiting patient volunteers.

Indiana is about more than swashbuckling archaeologists. The capital, Indianapolis, is home to the famous Indianapolis Motor Speedway and Indy 500. Other great cities in the state include Evansville, Fort Wayne, and Bloomington. Indiana is one of the nation's leaders in the automotive industry and has seen some of the strongest manufacturing job growth nationwide. Oddly enough, it is also one of the top states in producing professional basketball players. Those seeking quality healthcare in Indiana have lots of options, including Methodist Hospital in Indianapolis, part of Indiana University Health. It has the largest neuroscience critical care unit in America.

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1349 trials found

The Effects of Nedocromil Sodium and Cetirizine HCl on Exercise-induced Arterial Hypoxemia in Highly-trained Swimmers

NCT05095311

Exercise-induced arterial hypoxemia (EIAH), a reduced amount of oxygen in the arterial blood during exercise, has been observed in otherwise healthy, highly-trained endurance athletes during exercise at sea level. The extent of the arterial deoxygenation may be influenced by a histamine-mediated inflammatory response at the pulmonary capillary-alveolar membrane limiting oxygen diffusion. Moreover, while EIAH has been routinely explored in running and cycling, swimming is understudied despite pot ...

Conditions: Exercise-induced Arterial Hypoxemia

Medications in Breast Milk: A Convenience Pharmacokinetic Study

NCT05099484

The benefits of breastfeeding and human milk consumption by infants has been clearly demonstrated.1,2 Benefits to the infant include reduction of infant and childhood diseases and allergies. Benefits to the woman include more rapid return to pre-pregnancy weight and reduced risk of health problems such as cardiovascular disease and diabetes in the future. Many women take medications as part of their standard of care and for multiple medical reasons in the postpartum period, when breastfeeding oc ...

Conditions: Pregnancy Related

A Study of PTC923 in Participants With Phenylketonuria

NCT05099640

The main purpose of this trial is to evaluate the efficacy of PTC923 in reducing blood phenylalanine (Phe) levels in participants with phenylketonuria as measured by mean change in blood Phe levels from baseline to Weeks 5 and 6 (that is, the average of each respective treatment dose 2-week period of double-blind treatment).

Conditions: Phenylketonuria

Sentinel Lymph Node Biopsy for Cutaneous Squamous Cell Carcinoma of the Head and Neck

NCT05108090

The purpose of this study is to research if a type of biopsy known as sentinel lymph node biopsy (SLNB) can help in determining the rate of tumor deposits that are hard to detect and identify in node-negative cutaneous squamous cell carcinoma of the head or neck.

Conditions: Squamous Cell Carcinoma, Nonmelanoma Skin Cancer, Cutaneous Squamous Cell Carcinoma
Phase: Not Applicable

A Study of Donanemab (LY3002813) Compared With Aducanumab in Participants With Early Symptomatic Alzheimer's Disease (TRAILBLAZER-ALZ 4)

NCT05108922

The main purpose of this study is to compare donanemab to aducanumab on amyloid plaque clearance in participants with early symptomatic Alzheimer's Disease (AD).

Conditions: Mild Cognitive Impairment, Alzheimer Disease