Continuous Monitoring and Control of Hypoglycemia
NCT03340831
Recruiting
Evaluate safety of non-adjunctive CGM use in CGM naive participants.
Gender:
All
Ages:
2 years and above
Trial Updated:
09/17/2021
Locations: Iowa Diabetes & Endocrinology Research Center, Des Moines, Iowa
Conditions: Diabetes
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Determinants of Incident Stroke Cognitive Outcomes and Vascular Effects on RecoverY
NCT04916210
Recruiting
The overall goal of the DISCOVERY study is to better understand what factors contribute to changes in cognitive (i.e., thinking and memory) abilities in patients who experienced a stroke. The purpose of the study is to help doctors identify patients at risk for dementia (decline in memory, thinking and other mental abilities that significantly affects daily functioning) after their stroke so that future treatments may be developed to improve outcomes in stroke patients. For this study, a "stroke... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
06/03/2021
Locations: University of Iowa, Iowa City, Iowa
Conditions: Ischemic Stroke, Intracerebral Hemorrhage, Subarachnoid Hemorrhage, Dementia, Vascular, Mild Cognitive Impairment, Vascular Cognitive Impairment
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Enuresis Alarm - Is a Manual Trigger System Beneficial?
NCT03522818
Recruiting
The purpose of this study is to evaluate whether the bedwetting alarm trigger activated by parents to wake their child, in addition to the moisture alarm, will improve treatment success compared to the moisture alarm alone.
Gender:
All
Ages:
Between 5 years and 15 years
Trial Updated:
04/27/2021
Locations: University of Iowa, Iowa City, Iowa
Conditions: Enuresis, Nocturnal
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Cryoballoon vs. Rhythmia Guided Ablation for Recurrent AFib
NCT03811795
Recruiting
The purpose of this research is to evaluate whether cryoballoon ablation vs. radiofrequency ablation guided by high-fidelity mapping (Rhythmia) is the best treatment strategy to perform repeat ablation for recurrent atrial fibrillation after previously having undergone cryoballoon ablation.
Gender:
All
Ages:
Between 18 years and 100 years
Trial Updated:
03/29/2021
Locations: Iowa Heart Center, West Des Moines, Iowa
Conditions: Atrial Fibrillation
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STRIDE Biorepository
NCT02843347
Recruiting
The STRIDE Biorepository is an optional substudy available to participants in "Bone Marrow Transplantation vs Standard of Care in Patients with Severe Sickle Cell Disease (BMT CTN 1503) (STRIDE)".
Gender:
All
Ages:
Between 15 years and 40 years
Trial Updated:
02/05/2021
Locations: University of Iowa, Iowa City, Iowa
Conditions: Anemia, Sickle Cell
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The iotaSOFT Insertion System Safety Study
NCT04577118
Recruiting
Non-significant risk evaluation of the iotaSOFT Insertion System when used by a surgeon to assist with inserting a cochlear implant electrode array.
Gender:
All
Ages:
18 years and above
Trial Updated:
09/30/2020
Locations: University of Iowa, Iowa City, Iowa
Conditions: Cochlear Implant
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Musculoskeletal Impairment in Headaches Attributed to Rhinosinusitis
NCT04222244
Recruiting
Neck pain, neck muscle weakness, and limited neck range of motion have been shown in individuals with sinus headaches. Individuals in this previous study self-diagnosed their sinus headaches. It is unknown whether or not individuals who have been diagnosed with sinus headaches according to diagnostic criteria also present with musculoskeletal impairments. The purpose of this study is to determine if musculoskeletal neck impairments are present in individuals diagnosed with headaches attributed... Read More
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
09/17/2020
Locations: Des Moines University, Des Moines, Iowa
Conditions: Headache
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Study of Crenolanib vs Midostaurin Following Induction Chemotherapy and Consolidation Therapy in Newly Diagnosed FLT3 Mutated AML
NCT03258931
Recruiting
A phase III randomized multi-center study designed to compare the efficacy of crenolanib with that of midostaurin when administered following induction chemotherapy, consolidation chemotherapy and bone marrow transplantation in newly diagnosed AML subjects with FLT3 mutation. About 510 subjects will be randomized in a 1:1 ratio to receive either crenolanib in addition to standard first line treatment of AML (chemotherapy and if eligible, transplantation) (arm A) or midostaurin and standard treat... Read More
Gender:
All
Ages:
Between 18 years and 60 years
Trial Updated:
05/21/2020
Locations: University of Iowa Hospitals and Clinics, Iowa City, Iowa
Conditions: Newly Diagnosed FLT3 Mutated AML
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Pulmonary Hypertension Association Registry
NCT04071327
Recruiting
The PHA Registry (PHAR) is a national study about people who have pulmonary arterial hypertension (PAH) and chronic thromboembolic pulmonary hypertension (CTEPH). PHAR collects information from people with PAH and CTEPH who are cared for in participating PHA-accredited Pulmonary Hypertension Care Centers throughout the U.S. PHAR will determine how people with PAH and CTEPH are evaluated, tested, and treated, and will observe how well these participants do. The goal is to see if people with PH a... Read More
Gender:
All
Ages:
All
Trial Updated:
04/01/2020
Locations: University of Iowa Hospitals & Clinic, Iowa City, Iowa
Conditions: Pulmonary Arterial Hypertension, Chronic Thromboembolic Pulmonary Hypertension, Pulmonary Hypertension
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Caris Biorepository Research Protocol
NCT01499394
Recruiting
The Biorepository for Caris Life Sciences is designed for the purpose of making quality biospecimens and associated clinical data available for research studies related to advancing precision medicine and improving care for patients. The Caris Biorepository is a repository of prospectively collected biological specimens and associated clinical and demographic data gathered from multiple sources to be stored, used and shared for research. Caris Life Sciences will maintain the data and specimens... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
01/21/2020
Locations: The Iowa Clinic, PC, West Des Moines, Iowa
Conditions: Cancer
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Routine Cardiac Screening in Sarcoidosis Patients
NCT03902223
Recruiting
This protocol is an unblended randomized screening trial will have consecutive patients with no suggestion of cardiac sarcoidosis according to usual screening enroll in an enhanced screening protocol. The routine clinical care is to gather patient's history of symptoms and under go an ECG. If a patient has an abnormal results in standard screening, they typically have further evaluations as part of their routine medical care. These tests might include an echocardiogram, ambulatory ECG, and advan... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
08/12/2019
Locations: University of Iowa Hospital, Iowa City, Iowa
Conditions: Sarcoidosis, Cardiac Sarcoidosis, Boeck's Disease, Besnier-Boeck Disease
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Antibiotic Irrigations for Intra-Abdominal Drains
NCT03476941
Recruiting
Intra-abdominal abscesses are pus-filled pouches in the abdominal cavity. Current standard of care includes drain placement in the abscess cavity to reach source control as well as administration of systemic antibiotics. It is common practice to flush the drain on a daily basis to ensure patency. This study aims to analyze the clinical impact of a higher local concentration of antibiotics (rather than normal saline) provided through drain irrigation with an antimicrobial agent (Gentamicin and/or... Read More
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
06/05/2019
Locations: The University of Iowa, Iowa City, Iowa
Conditions: Abdominal Abscess
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