Kansas is currently home to 948 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Wichita, Kansas City, Overland Park and Topeka. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Function of Circulating Exosomes in Sepsis-induced Immunosuppression
NCT04979767
Recruiting
This is a single-center prospective bio-specimen analysis and observational study aiming to define immune pathways disrupted in bacterial sepsis and to identify clinically useful biomarkers of immune status.
Gender:
All
Ages:
50 years and above
Trial Updated:
07/16/2021
Locations: University of Kansas Medical Center, Kansas City, Kansas
Conditions: Sepsis, Septic Shock, Sepsis Syndrome, Sepsis Bacterial, Sepsis, Severe, Sepsis Bacteremia
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Multi-Center Study to Evaluate the Efficacy and Safety of Sildenafil Cream (3.6%) in Premenopausal Patients With Female Sexual Arousal Disorder
NCT04948151
Recruiting
This study is looking to minimize side effects, while maintaining and potentially improving the therapeutic benefit to patients suffering from Female Sexual Arousal Disorder by providing a topical preparation of Sildenafil locally to the vulvar-vaginal tissue.
Gender:
Female
Ages:
21 years and above
Trial Updated:
06/24/2021
Locations: Cypress Medical Research Center, Wichita, Kansas
Conditions: Female Sexual Arousal Disorder
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Pulmonary Hypertension Biorepository and Registry
NCT04808596
Recruiting
Establish a pulmonary hypertension registry and biorepository to lead towards a further understanding of the disease.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/27/2021
Locations: The University of Kansas Medical Center, Kansas City, Kansas
Conditions: Pulmonary Hypertension, Pulmonary Arterial Hypertension, Pulmonary Hypertension Due to Left Heart Disease, Pulmonary Hypertension, Primary, Pulmonary Hypertension Due to Lung Diseases and Hypoxia, Pulmonary Hypertension, Primary, 4, Pulmonary Hypertension, Primary, 2, Pulmonary Hypertension, Primary, 3, Chronic Thromboembolic Pulmonary Hypertension
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Evaluation of Multi-Tined Expandable Electrode (MEE) Efficacy and Safety in Treatment of Lumbar Facet Arthropathy by Radiofrequency Neurotomies Compared to Conservative Medical Management.
NCT04730700
Recruiting
The purpose of this study is to better understand how people feel after a radiofrequency ablation standard of care surgery using a different type of needle (multi-tined expandable electrode/MEE) in comparison to receiving conventional medical management (CMM) techniques.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/06/2021
Locations: University of Kansas Medical Center, Kansas City, Kansas
Conditions: Chronic Low-back Pain
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Early PKD Observational Cohort Study
NCT02936791
Recruiting
This observational study will collect blood and urine and clinical information from individuals with early-stages of polycystic kidney disease (PKD), their unaffected siblings and normal volunteers to create a biobank, also called a biorepository. The long-term goal is to develop new knowledge on biological markers or biomarkers that indicate changes in the disease progression. An understanding of biomarkers for early renal cyst growth will benefit PKD patients as new therapies are being develop... Read More
Gender:
All
Ages:
Between 4 years and 35 years
Trial Updated:
05/06/2021
Locations: University of Kansas Medical Center, Kansas City, Kansas
Conditions: Polycystic Kidney Disease
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Study Investigating the Efficacy of Crenolanib With Chemotherapy vs Chemotherapy Alone in R/R FLT3 Mutated AML
NCT03250338
Recruiting
This is a randomized, multi-center, double-blind, placebo-controlled study designed to evaluate the efficacy of crenolanib administered following salvage chemotherapy, consolidation chemotherapy, post bone marrow transplantation and as maintenance in relapsed/refractory AML subjects with FLT3 activating mutation.
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
04/28/2021
Locations: Kansas University, Kansas City, Kansas
Conditions: Relapsed/Refractory Acute Myeloid Leukemia With FLT3 Activating Mutations
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Hypofractionated Radiation Therapy for Patients With Breast Cancer Receiving Regional Nodal Irradiation
NCT02958774
Recruiting
The primary objective of this study is to document lymphedema rates in patients requiring regional nodal irradiation (RNI) who receive hypofractionated radiation as compared to conventional radiation.
Gender:
Female
Ages:
18 years and above
Trial Updated:
04/14/2021
Locations: University of Kansas Medical Center, Kansas City, Kansas
Conditions: Breast Cancer
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Epidural Spinal Cord Stimulation for Hypertension in Patients With Neuropathic Pain
NCT04598035
Recruiting
The purpose of the ESCAPE Study is to determine the extent to which epidural spinal cord stimulation (SCS) reduces arterial blood pressure (BP) in patients which chronic low back pain and hypertension. We also aim to determine the extent to which higher baseline BP (i.e., hypertension) predicts reductions in pain following SCS implant. This is an observational study of patients undergoing an implantation of a SCS device.
Gender:
All
Ages:
Between 30 years and 89 years
Trial Updated:
01/28/2021
Locations: University of Kansas Clinical and Translational Science Unit (CTSU), Fairway, Kansas
Conditions: Chronic Pain, Hypertension, Implanted Stimulation Electrodes
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An Active and Placebo-Controlled Study of Brazikumab in Participants With Moderately to Severely Active Ulcerative Colitis
NCT04718818
Recruiting
The present study D5272C00001 (Legacy # 3151-201-008) seeks to evaluate the efficacy and safety of brazikumab versus placebo in patients with moderately to severely active UC and will include assessments of clinical responses as demonstrated by improvement of symptoms and of colonic mucosal appearance as observed on endoscopy.
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
01/19/2021
Locations: Research Site, Shawnee Mission, Kansas
Conditions: Ulcerative Colitis
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Study in Relapsed/Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome Patients to Determine the Recommended Dose of CYAD-02
NCT04167696
Recruiting
An open-label, phase I, multi-center study to determine in relapsed/refractory (r/r) acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS) patients the recommended dose of CYAD-02 after a non-myeloablative preconditioning chemotherapy followed by a potential CYAD-02 consolidation cycle for non-progressive patient. A maximum of 27 r/r AML/MDS patients will be evaluated in this study in case of no dose limiting toxicity (DLT) and no replacement of patients.
Gender:
All
Ages:
18 years and above
Trial Updated:
06/08/2020
Locations: University of Kansas Cancer Center, Fairway, Kansas
Conditions: Acute Myeloid Leukemia, Myelodysplastic Syndrome
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Study of Crenolanib vs Midostaurin Following Induction Chemotherapy and Consolidation Therapy in Newly Diagnosed FLT3 Mutated AML
NCT03258931
Recruiting
A phase III randomized multi-center study designed to compare the efficacy of crenolanib with that of midostaurin when administered following induction chemotherapy, consolidation chemotherapy and bone marrow transplantation in newly diagnosed AML subjects with FLT3 mutation. About 510 subjects will be randomized in a 1:1 ratio to receive either crenolanib in addition to standard first line treatment of AML (chemotherapy and if eligible, transplantation) (arm A) or midostaurin and standard treat... Read More
Gender:
All
Ages:
Between 18 years and 60 years
Trial Updated:
05/21/2020
Locations: University of Kansas, Kansas City, Kansas
Conditions: Newly Diagnosed FLT3 Mutated AML
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Pulmonary Hypertension Association Registry
NCT04071327
Recruiting
The PHA Registry (PHAR) is a national study about people who have pulmonary arterial hypertension (PAH) and chronic thromboembolic pulmonary hypertension (CTEPH). PHAR collects information from people with PAH and CTEPH who are cared for in participating PHA-accredited Pulmonary Hypertension Care Centers throughout the U.S. PHAR will determine how people with PAH and CTEPH are evaluated, tested, and treated, and will observe how well these participants do. The goal is to see if people with PH a... Read More
Gender:
All
Ages:
All
Trial Updated:
04/01/2020
Locations: KU Medical Center, Kansas City, Kansas
Conditions: Pulmonary Arterial Hypertension, Chronic Thromboembolic Pulmonary Hypertension, Pulmonary Hypertension
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