Michigan is currently home to 2175 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Ann Arbor, Detroit, Grand Rapids and Kalamazoo. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
ZIP Study-OL Study of Safety, PK, Efficacy, PD, Immunogenicity of ATB200/AT2221 in Pediatrics Aged 0 to < 18 y.o. w/LOPD
NCT03911505
Recruiting
This is a Phase 3, open-label, multicenter study to evaluate the safety, PK, efficacy, PD, and immunogenicity of Cipaglucosidase Alfa/Miglustat treatment in enzyme replacement therapy (ERT)-experienced and ERT-naïve pediatric subjects with Pompe disease, aged 0 to \< 18 years
Gender:
ALL
Ages:
Between 0 years and 17 years
Trial Updated:
09/16/2024
Locations: Infusion Associates, Grand Rapids, Michigan
Conditions: Pompe Disease (Late-onset)
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Pilot Open-Label Trial of Resistant Potato Starch in Patients with Cirrhosis and Overt Hepatic Encephalopathy
NCT06425380
Recruiting
This research is studying how a food product (resistant potato starch) which is a dietary supplement made from potato starch affects the gut bacteria of people with cirrhosis and hepatic encephalopathy. The researchers in this study want to understand how potato starch works in the subject's body and how the body will react to it. Along with taking the study product participants health-related information and stool will be collected for this research study.
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
09/15/2024
Locations: University of Michigan, Ann Arbor, Michigan
Conditions: Hepatic Encephalopathy, Cirrhosis
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Food-Body-Mind Intervention (16 Weeks)
NCT06597474
Recruiting
This novel, timely, and theory-driven Food-Body-Mind intervention addresses the national emergency of mental health crises in early childhood. By targeting Head Start racially/ethnically diverse preschoolers from low-income backgrounds in both urban and rural areas, this intervention is expected to contribute toward reducing health disparities and promoting health equity, a major priority of the NIH and Healthy People 2030. If effective, it can be scalable to Head Start programs across urban and... Read More
Gender:
ALL
Ages:
Between 3 years and 5 years
Trial Updated:
09/13/2024
Locations: Community Action Agency, Jackson, Michigan
Conditions: Mental Health Wellness, Emotional Problem, Behavioral Problem of Child, Social Skills, Obesity, Childhood
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Safety and Efficacy Study of NUV-1511 in Adult Patients With Advanced Solid Tumors
NCT06334432
Recruiting
NUV-1511-01 is a first-in human, open- label, Phase 1/2 to evaluate the safety and efficacy of NUV-1511 in patients with advanced solid tumors. The Phase 1 portion include patients with advanced solid tumors and is designed to determine the safety and the tolerability of doses of NUV-1511. In Phase 2, NUV-1511 will be given to determine the efficacy of patients with advanced solid tumors.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/13/2024
Locations: Karmanos Cancer Center, Detroit, Michigan
Conditions: Advanced Solid Tumor, HER2-negative Breast Cancer, Metastatic Castration-resistant Prostate Cancer (mCRPC), Pancreatic Cancer, Platinum-resistant Ovarian Cancer (PROC)
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Carboplatin or Olaparib for BRcA Deficient Prostate Cancer
NCT04038502
Recruiting
This is an unblinded, randomized clinical study comparing the efficacy of DNA damaging chemotherapy using carboplatin, to standard of care therapy for patients who have metastatic castrate resistant prostate cancer. This trial will use olaparib or carboplatin as initial therapy with crossover to the alternate or second-line drug after first progression for patients with tumors containing BARD1, BRCA1, BRCA2, BRIP1, CHEK1, FANCL, PALB2, RAD51B, RAD51C, RAD51D, or RAD54L inactivating mutations. P... Read More
Gender:
MALE
Ages:
18 years and above
Trial Updated:
09/13/2024
Locations: VA Ann Arbor Healthcare System, Ann Arbor, MI, Ann Arbor, Michigan
Conditions: Metastatic Castrate Resistant Prostate Cancer, BARD1, BRCA1, BRCA2, BRIP1, CHEK1, FANCL, PALB2, RAD51B, RAD51C, RAD51D, or RAD54L Mutations
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Increasing Effectiveness of an Alcohol Use Reduction Exercise Using Self-Talk Videos
NCT06593483
Recruiting
The goal of the current study is to develop and test an innovative, low-burden method of post-intervention contact that is based on principles of motivational interviewing and the elicitation of change talk. Participants will be randomly assigned to an assessment only control group, a standard BMI group or a BMI + video group. Participants in the BMI and BMI + video groups will complete a semi-structured, motivational intervention. Following the intervention, participants in the BMI + video grou... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/12/2024
Locations: Wayne State University, Detroit, Michigan
Conditions: Heavy Drinking
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Emsella Chair Vs Sham for Male Sexual Dysfunction
NCT05370651
Recruiting
We will be performing this study in 2 phases: Phase 1 will be an open label pilot study of 10 male participants. All participants in the pilot study will receive active treatment. If data from the pilot study is suggestive of symptom improvement, we will continue on to phase 2, which is a sham controlled, randomized blinded study. Participants in phase 2 will be randomized to receive either active treatment or sham. Potentially total of 114 participants for both phases will be enrolled. The pur... Read More
Gender:
MALE
Ages:
18 years and above
Trial Updated:
09/12/2024
Locations: Beaumont Hospital Royal Oak, Royal Oak, Michigan
Conditions: Ejaculatory Dysfunction, Male Sexual Dysfunction
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BTL Emsella Chair Versus Sham for the Treatment of Overactive Bladder
NCT04873037
Recruiting
The purpose of this clinical trial is to compare the Emsella Chair therapy to Sham and to determine whether electromagnetic technology is effective in the treatment of overactive bladder (OAB). Currently there are no other studies utilizing the Emsella Chair for the treatment of OAB. Eligible subjects will receive 2 treatments per week for a total of 4 weeks.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/12/2024
Locations: Beaumont Hospital - Royal Oak, Royal Oak, Michigan
Conditions: Overactive Bladder Syndrome, Overactive Bladder, Urinary Frequency, Urinary Urgency
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Bladder Directed Vs. Pelvic Floor Therapy in IC/BPS
NCT02870738
Recruiting
Women with interstitial cystitis/bladder pain syndrome (IC/BPS) have debilitating urinary frequency and urgency, and chronic pelvic or bladder pain perceived to be related to the bladder. Although many clinicians think that IC/BPS symptoms result from a bladder problem, tight pelvic floor muscles can cause similar symptoms and might be responsible for ICBPS symptoms instead of the bladder. Inadequate assessment of the problem leads to delays in treatment and often years of suffering. This clinic... Read More
Gender:
FEMALE
Ages:
Between 18 years and 85 years
Trial Updated:
09/12/2024
Locations: William Beaumont Hospital, Royal Oak, Michigan
Conditions: Cystitis, Interstitial, Painful Bladder Syndrome
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Safety and Effectiveness of the Globe® Pulsed Field System for Treating Patients With Symptomatic Paroxysmal or Persistent Atrial Fibrillation
NCT05462145
Recruiting
This study will evaluate the safety and effectiveness of the Globe® Pulsed Field System for treating patients with symptomatic paroxysmal or persistent atrial fibrillation (AF).
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
09/11/2024
Locations: Beaumont Hospital, Royal Oak, Michigan
Conditions: Paroxysmal Atrial Fibrillation, Persistent Atrial Fibrillation
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Project IntERact V2
NCT05109325
Recruiting
The present study is evaluating the efficacy of a behavioral intervention to reduce risky firearm carriage among a high risk sample of youth reporting recent firearm carriage and ownership of a smartphone.
Gender:
ALL
Ages:
Between 16 years and 30 years
Trial Updated:
09/11/2024
Locations: University of Michigan, Ann Arbor, Michigan
Conditions: Firearm Violence, Firearm Carriage, Injury Prevention
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PReclude Infection EVEnts With No Prophylaxis Transperineal Biopsy 2
NCT04815876
Recruiting
Approximately one million transrectal prostate biopsies are performed annually in the U.S., and the risk of post- biopsy infection is increasing due to greater antibiotic resistance of rectal flora. Preliminary data demonstrates that a transperineal MRI-targeted biopsy approach under local anesthesia compared to the standard practice transrectal MRI-targeted prostate biopsy has a much lower risk of infection, comparable pain/discomfort and may improve detection of prostate cancer. This randomiz... Read More
Gender:
MALE
Ages:
18 years and above
Trial Updated:
09/11/2024
Locations: University of Michigan, Ann Arbor, Michigan
Conditions: Infection
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