Michigan is currently home to 2246 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Ann Arbor, Detroit, Grand Rapids and Kalamazoo. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Optimal Post Tpa-Iv Monitoring in Ischemic Stroke
NCT03734640
Recruiting
OPTIMISTmain is an investigator-initiated and conducted, international, multicentre, stepped wedge cluster randomized controlled trial comparing the effects of different intensities of nursing care monitoring for patients with acute ischemic stroke of mild severity and without critical care needs after IV-tPA.
Gender:
All
Ages:
18 years and above
Trial Updated:
08/11/2023
Locations: Henry Ford Health System, Detroit, Michigan
Conditions: Acute Ischemic Stroke Patients Receiving Reperfusion Therapy
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Standard Systemic Therapy With or Without Definitive Treatment in Treating Participants With Metastatic Prostate Cancer
NCT03678025
Recruiting
This phase III trial studies how well standard systemic therapy with or without definitive treatment (prostate removal surgery or radiation therapy) works in treating participants with prostate cancer that has spread to other places in the body. Addition of prostate removal surgery or radiation therapy to standard systemic therapy for prostate cancer may lower the chance of the cancer growing or spreading.
Gender:
Male
Ages:
18 years and above
Trial Updated:
08/11/2023
Locations: Saint Joseph Mercy Hospital, Ann Arbor, Michigan
Conditions: Castration Levels of Testosterone, Metastatic Prostatic Adenocarcinoma, Stage IV Prostate Cancer AJCC v8, Stage IVA Prostate Cancer AJCC v8, Stage IVB Prostate Cancer AJCC v8
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The CHILD Trial: Hypoplastic Left Heart Syndrome Study.
NCT03406884
Recruiting
The objectives of this pilot study are to evaluate the feasibility and safety of intramyocardial injection of autologous c-kit+ cells during the Stage II BDCPA operation and to observe effects on clinical outcome including right ventricular myocardial function, severity of tricuspid regurgitation, incidence of serious adverse events, re-hospitalizations, changes in health status, the need for transplantation, or mortality.
Gender:
All
Ages:
Between 1 day and 21 days
Trial Updated:
08/11/2023
Locations: Michigan Medicine Congenital Heart Center/C.S. Mott Children's Hospital, Ann Arbor, Michigan
Conditions: Hypoplastic Left Heart Syndrome
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Transcutaneous Vibro-Acoustic Therapy in Parkinson Disease
NCT05962476
Recruiting
Small exploratory pilot study to assess effects of a transcutaneous vibro-acoustic therapy device (Apollo Neuro) in people with Parkinson's disease (PD).
Gender:
All
Ages:
40 years and above
Trial Updated:
08/10/2023
Locations: Domino's Farms, Ann Arbor, Michigan
Conditions: Parkinson Disease
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Comprehensive Genomic Analysis in Tissue Samples From Patients With Recurrent or Stage IV Non-small Cell Lung Cancer
NCT02178163
Recruiting
This research trial studies comprehensive genomic analysis in tissue samples from patients with non-small cell lung cancer that has come back or is stage IV. Comprehensive genomic analysis may identify specific gene mutations (changes in deoxyribonucleic acid [DNA]) and help doctors to tailor treatment to target the specific mutations.
Gender:
All
Ages:
18 years and above
Trial Updated:
08/10/2023
Locations: KCI at McLaren Bay Region, Bay City, Michigan
Conditions: Recurrent Non-small Cell Lung Cancer, Stage IV Non-small Cell Lung Cancer
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Identification of Phenotypic Factors That Predict Success for Weight Loss and Long-term Weight Maintenance
NCT02043457
Recruiting
The Investigational Weight Management Clinic now entitled the Weight Management Program at the University of Michigan was created to identify strategies that will result in cost-effective, long term weight management for overweight and obese individuals. The driving hypothesis of the clinic is that the 'one size fits all' philosophy is untenable with a complex disease such as obesity. The clinic will serve as a portal for patients to choose standard clinical care or to explore alternatives from... Read More
Gender:
All
Ages:
Between 15 years and 75 years
Trial Updated:
08/09/2023
Locations: University of Michigan, Ann Arbor, Michigan
Conditions: Obesity
Register for Updates
Genomic Predictors of Recurrent Pregnancy Loss
NCT05444283
Recruiting
The overall goals of this proposal are to determine the genetic architecture of recurrent pregnancy loss (RPL) and to discover genomic predictors of RPL.
Gender:
All
Ages:
Between 18 years and 50 years
Trial Updated:
08/08/2023
Locations: Wayne State University, Detroit, Michigan
Conditions: Recurrent Pregnancy Loss
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Neonatal Seizure Registry - Developmental Functional EValuation
NCT04337697
Recruiting
The NSR-DEV study is a longitudinal cohort study of around 280 Neonatal Seizure Registry participants that aims to evaluate childhood outcomes after acute symptomatic neonatal seizures, as well as examine risk factors for developmental disabilities and whether these are modified by parent well-being.
Gender:
All
Ages:
Between 2 years and 8 years
Trial Updated:
08/08/2023
Locations: University of Michigan, Ann Arbor, Michigan
Conditions: Neonatal Seizure, Hypoxic-Ischemic Encephalopathy, Stroke, Intracranial Hemorrhages, Epilepsy, Cerebral Palsy, Intellectual Disability
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Leveraging Virtual Care Strategies to Improve Access and Treatment for Individuals With Alcohol Use Disorders
NCT05594238
Recruiting
The purpose of this research study is to test new technology-driven programs to see if they might help people manage their health and health behaviors related to alcohol use and well-being. The programs focus on getting to know what's important to participants, reviewing or setting goals, and using different skills and behaviors to manage health. The study will help researchers learn about ways to deliver health information in a way that is useful and interesting.
Gender:
All
Ages:
Between 18 years and 70 years
Trial Updated:
08/07/2023
Locations: University of Michigan, Ann Arbor, Michigan
Conditions: Alcohol Use Disorder
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Specimen Collection From Pregnant Women at Increased Risk for Fetal Aneuploidy
NCT01429389
Recruiting
The specimen collection is designed for the purpose of the development of a noninvasive prenatal test for T21.
Gender:
Female
Ages:
18 years and above
Trial Updated:
08/07/2023
Locations: Henry Ford Hospital, Detroit, Michigan
Conditions: Down Syndrome, Fetal Aneuploidy
Register for Updates
A Randomized Control Trial Assessing the Effect of Topical Tranexamic Acid on Risk of Hematoma in Breast Surgery
NCT05441592
Recruiting
This trial is being completed to evaluate the safety and efficacy of topical tranexamic acid use in preventing hematomas in routine breast plastic surgery operations.
Gender:
All
Ages:
18 years and above
Trial Updated:
08/03/2023
Locations: University of Michigan, Ann Arbor, Michigan
Conditions: Hematoma Postoperative
Register for Updates
The Breakfast Study
NCT05986097
Recruiting
The investigators will conduct an acceptability, feasibility, preliminary effectiveness trial of a 4-month, online, very low-carbohydrate breakfast-focused program in 120 adults with type 2 diabetes. The investigators will measure acceptability and feasibility, plus critical efficacy outcomes, such as changes in HbA1c, anti-hyperglycemic medications, glycemic variability, body weight, blood pressure, and lipids.
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
08/02/2023
Locations: University of Michigan, Ann Arbor, Michigan
Conditions: Type 2 Diabetes
Register for Updates