Michigan is currently home to 2248 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Ann Arbor, Detroit, Grand Rapids and Kalamazoo. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Use of Consumer Sleep Technology to Treat Shift Work Disorder
Recruiting
The purpose of this study is to examine the effectiveness of a personalized light exposure schedule for Shift Work Disorder (SWD) in night shift workers compared to a non-personalized light exposure schedule.
Gender:
All
Ages:
18 years and above
Trial Updated:
07/18/2023
Locations: Henry Ford Columbus Medical Center, Novi, Michigan
Conditions: Shift-work Disorder
VIA Disc NP Registry
Recruiting
Registry is to observe and trend patterns of care and outcomes for patients treated with VIA Disc NP.
Gender:
All
Ages:
18 years and above
Trial Updated:
07/18/2023
Locations: Michigan Interventional Pain Center, Brownstown, Michigan
Conditions: Discogenic Pain, Back Pain, Back Pain, Low
Sustained Immunity to COVID-19 as Measured by SARS-CoV-2 Serology Assays
Recruiting
The primary objective is to assess the ability of COVID-19 IgG and IgM assays to detect an immune response in COVID-19 patients in the Henry Ford Health System (HFHS), both during hospitalization and over the following 12 months.
Gender:
All
Ages:
18 years and above
Trial Updated:
07/18/2023
Locations: Henry Ford Health System, Detroit, Michigan
Conditions: Covid19
Surveillance and Treatment to Prevent Fetal Atrioventricular Block Likely to Occur Quickly (STOP BLOQ)
Recruiting
Fetal complete (i.e., third degree, 3°) atrioventricular block (AVB), identified in the 2nd trimester of pregnancy in an otherwise normally developing heart, is almost universally associated with maternal anti-Ro autoantibodies and results in death in a fifth of cases. To date treatment of 3° AVB has been ineffective in restoring normal rhythm (NR) which may be because current surveillance is limited to once- weekly fetal echocardiograms. It is hypothesized that there may be a vital transition p... Read More
Gender:
Female
Ages:
18 years and above
Trial Updated:
07/18/2023
Locations: University of Michigan / C. S. Mott Children's Hospital, Ann Arbor, Michigan
Conditions: AVB - Atrioventricular Block, Fetal AVB
Pilot-Tart Cherry, Mitral Transcriptome, and POAF Incidence
Recruiting
Assess impact of Tart Cherry Concentrate in cardiac surgical patients on POAF and related clinical and economic outcomes. Measure inflammation gene transcripts in cardiac tissue.
Gender:
All
Ages:
Between 50 years and 79 years
Trial Updated:
07/18/2023
Locations: University of Michigan, Ann Arbor, Michigan
Conditions: Post-operative Atrial Fibrillation (POAF)
A Study to Evaluate the Safety (Compared to Iron Sucrose), Efficacy and Pharmacokinetics of Ferumoxytol for the Treatment of Iron Deficiency Anemia (IDA) in Pediatric Subjects With Chronic Kidney Disease (CKD)
Recruiting
Primary Objectives: To evaluate the safety (compared to iron sucrose) and efficacy of ferumoxytol in pediatric CKD subjects with iron deficiency anemia (IDA) or who are at risk of development of IDA Secondary Objective: To determine the single-dose pharmacokinetics (PK) and pharmacodynamics (PD) profile of ferumoxytol in pediatric subjects.
Gender:
All
Ages:
Between 2 years and 17 years
Trial Updated:
07/18/2023
Locations: Wayne State University, Detroit, Michigan
Conditions: Chronic Kidney Disease; Iron Deficiency Anemia
A Study of MORAb-202 in Participants With Previously Treated Metastatic Non-Small Cell Lung Cancer (NSCLC) Adenocarcinoma (AC)
Recruiting
The aim of this study is to characterize the safety and tolerability of MORAb-202, and to assess the objective response rate in participants with previously treated, metastatic NSCLC AC.
Gender:
All
Ages:
18 years and above
Trial Updated:
07/17/2023
Locations: Henry Ford Hospital, Detroit, Michigan
Conditions: Carcinoma, Non-Small-Cell Lung
Peer Navigation for Individuals With Serious Mental Illness Leaving Jail
Recruiting
Serious mental illness (SMI) is a burdensome and widely prevalent public health problem among incarcerated men and women. Incarcerated individuals with SMI re-entering the community after jail stay experience the double stigma of criminal justice involvement and having the diagnosis of SMI. As a result, they are likely to disengage with community level mental health, medical care and substance use services at re-entry. This study proposes the development and pilot test of peer navigator interven... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
07/14/2023
Locations: Genesee County Jail, Flint, Michigan
Conditions: Individuals With Serious Mental Illness Leaving Jails
Study BT5528-100 in Patients With Advanced Solid Tumors Associated With EphA2 Expression
Recruiting
This clinical trial is evaluating a drug called BT5528 alone and in combination with nivolumab in participants with advanced solid tumors historically known for expression of EphA2. The main goals of this study are to: Find the recommended dose(s) of BT5528 that can be given safely to participants alone and in combination with nivolumab Learn more about the side effects of BT5528 Learn about how effective BT5528 is for the treatment of ovarian cancer, urothelial/bladder cancer, lung cancer (NSC... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
07/14/2023
Locations: Barbara Ann Karmanos Cancer Institute, Detroit, Michigan
Conditions: Advanced Solid Tumor Historically Known for High EphA2 Expression, Urothelial Cancer, Ovarian Cancer, Non-small Cell Lung Cancer, Head and Neck Cancer, Triple Negative Breast Cancer, Gastric/Upper Gastrointestinal Cancer
Study Comparing Ultrasound-guided FICNB Block to Systemic Analgesia in Treatment of Pediatric Femur Fracture
Recruiting
The goal of this prospective observational study is to compare pain control strategies in children with femur fractures. Researchers will compare ultrasound-guided fascia iliaca compartment nerve block to IV pain control alone. The main questions it aims to answer are: Are ultrasound-guided fascia iliaca compartment nerve blocks as effective as IV pain control in controlling pain? Do patients who receive an ultrasound-guided fascia iliaca compartment nerve block require less opioid pain medicat... Read More
Gender:
All
Ages:
Between 4 years and 17 years
Trial Updated:
07/12/2023
Locations: University of Michigan, Ann Arbor, Michigan
Conditions: Femur Fracture
REC 0/0559 Eye Drops for Treatment of Moderate and Severe Neurotrophic Keratitis in Adult Patients
Recruiting
A phase 2 study, aiming to evaluate the efficacy, safety and pharmacokinetics of REC 0/0559 in treatment of Neurotrophic Keratitis in Adult Patient in Europe and United States of America.
Gender:
All
Ages:
18 years and above
Trial Updated:
07/12/2023
Locations: University of Michigan - Kellogg Eye Center, Ann Arbor, Michigan
Conditions: Neurotrophic Keratitis
Effects of Delta9-tetrahydrocannabinol (THC) on Retention of Memory for Fear Extinction Learning in PTSD: R33 Study
Recruiting
The goal of this study is to look at how a type of drug called cannabinoids are related to the processing of fear signals, the experience of emotions and fear, and the pattern of activity in the brain that is involved in these processes and how this relates to the treatment of post-traumatic stress disorder (PTSD). PTSD is an anxiety disorder that occurs after experiencing a traumatic event(s) and is characterized by unwanted memories of the trauma(s) through flashbacks or nightmares, avoidance... Read More
Gender:
All
Ages:
Between 18 years and 60 years
Trial Updated:
07/12/2023
Locations: Eugene Applebaum College of Pharmacy and Health Sciences, Detroit, Michigan
Conditions: Posttraumatic Stress Disorder