Michigan is currently home to 2171 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Ann Arbor, Detroit, Grand Rapids and Kalamazoo. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Terumo Aortic Global Endovascular Registry
Recruiting
Multi-arm, multi-center, open label, prospective observational registry designed to obtain safety and performance data on the use of CE marked and custom Terumo Aortic endovascular grafts.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/19/2023
Locations: University of Michigan, Ann Arbor, Michigan
Conditions: Abdominal Aortic Aneurysm, Thoracic Aortic Aneurysm, Surgery
TRIAD Appendicitis Decision-making Surveys
Recruiting
While appendectomy has been the main treatment of appendicitis for over 100 years, recent European studies found that, at least among highly selected patients, antibiotics alone can be an effective alternative. Surgeons and patients alike have a difficult time deciding if surgery or antibiotics are the best choice to treat appendicitis. The goal of the TRIAD is to evaluate the patients who are a part of the TRIAD implementation program and assess satisfaction and decisional regret for patients w... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/13/2023
Locations: Michigan Medicine- University of Michigan, Ann Arbor, Michigan
Conditions: Appendicitis
The Role of Osteopathic Manipulative Medicine in Recovery From Concussions
Recruiting
This project aims to study whether adding osteopathic manipulative treatment (OMT) to usual care of concussed patients will enhance their recovery.
Gender:
ALL
Ages:
Between 13 years and 55 years
Trial Updated:
06/13/2023
Locations: MSU Center for Orthopedic Research, East Lansing, Michigan
Conditions: Concussion, Brain
Standardized Invasive Hemodynamics for Elevated Gradients Post TAVR (DISCORDANCE TAVR)
Recruiting
The DISCORDANCE TAVR study will determine the discordance between echocardiography-derived and invasive transaortic gradients, as determined by a consistent and reproducible technique (Standardized Invasive Hemodynamics) post-TAVR.
Gender:
ALL
Ages:
All
Trial Updated:
06/06/2023
Locations: William Beaumont Hospital, Southfield, Michigan
Conditions: Aortic Stenosis, Aortic Valve Stenosis
GCC19CART for Patients With Metastatic Colorectal Cancer
Recruiting
Study ICT-GCC19CART-US-001 (CARAPIA-1) is a Phase 1 study evaluating the safety, tolerability, clinical activity, pharmacokinetics and pharmacodynamics of GCC19CART in subjects with relapsed or refractory metastatic colorectal cancer.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/02/2023
Locations: University of Michigan Comprehensive Cancer Center, Ann Arbor, Michigan
Conditions: Colorectal Cancer
SBRT +/- Pembrolizumab in Patients With Local-Regionally Recurrent or Second Primary Head and Neck Carcinoma
Recruiting
This phase II trial with a safety run-in component will evaluate whether the addition of pembrolizumab to Stereotactic Body Radiation Therapy (SBRT) re-irradiation will improve the progression-free survival for patients with recurrent or new second primary Head and Neck Squamous Cell Carcinoma (HNSCC).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/01/2023
Locations: Henry Ford Hospital, Detroit, Michigan
Conditions: Head and Neck Squamous Cell Carcinoma (HNSCC)
A Dose Escalation With Expansion Study of EMB-01 in Participants With Advanced/Metastatic Solid Tumors
Recruiting
First-in-human, Phase I/II, Multicenter, Open-Label Study of EMB-01 in Patients with Advanced/Metastatic Solid Tumors
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/30/2023
Locations: Barbara Ann Karmanos Cancer Institute, Detroit, Michigan
Conditions: Neoplasms, Neoplasm Metastasis, Non-Small-Cell Lung Cancer
Natural History Study of and Genetic Modifiers in Spinocerebellar Ataxias
Recruiting
Spinocerebellar ataxias (SCA) are genetic neurological diseases that cause imbalance, poor coordination, and speech difficulties. There are different kinds of SCA and this study will focus on types 1, 2,3, and 6 (SCA 1, SCA 2, SCA 3 , also known as Machado-Joseph disease and SCA 6). The diseases are rare, slowly progressive, cause increasingly severe neurological difficulties and are variable across and within genotypes. The purpose of this research study is to bring together a group of experts... Read More
Gender:
ALL
Ages:
6 years and above
Trial Updated:
05/30/2023
Locations: University of Michigan, Ann Arbor, Michigan
Conditions: Spinocerebellar Ataxia Type 1, Spinocerebellar Ataxia Type 2, Spinocerebellar Ataxia Type 3, Spinocerebellar Ataxia Type 6
International CIPN Assessment and Validation Study
Recruiting
This is an observational study of chemotherapy-induced peripheral neurotoxicity (CIPN) patients to be investigated prospectively in order to assess responsiveness of a set of outcome measures in an international multi-center study.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/24/2023
Locations: University of Michigan School of Nursing, Ann Arbor, Michigan
Conditions: Chemotherapy-induced Peripheral Neuropathy, Quality of Life
Study of Single Oral Doses of HOPO 14-1 Evaluating Safety, Tolerability, Pharmacokinetics
Recruiting
The study objectives are to define the safety and tolerability profile of oral, single ascending dose (SAD) levels of HOPO 14-1 capsules in cohorts of healthy participants and to assess the pharmacokinetic (PK) and excretion profile of HOPO 14-1. The study hypothesis is that a single dose of HOPO 14-1 will be safe and tolerable up to 7500 mg.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
05/22/2023
Locations: SRI Biosciences Clinical Trials Unit, Plymouth, Michigan
Conditions: Toxicity;Chemical
Battlefield Acupuncture for Pain in Hidradenitis Suppurativa
Recruiting
The investigators will investigate battlefield acupuncture as a treatment for the pain of hidradenitis suppurativa.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/12/2023
Locations: WSUPG Dermatology, Dearborn, Michigan
Conditions: Hidradenitis Suppurativa
Preventing Impaired Driving Among Adolescents
Recruiting
The primary goal of this project is to evaluate the efficacy of webCHAT, a single-session web-intervention, on reducing impaired driving among adolescents receiving behind-the-wheel training at driver education programs.
Gender:
ALL
Ages:
Between 15 years and 17 years
Trial Updated:
05/04/2023
Locations: DriveSafe Driving School, Dearborn, Michigan
Conditions: Substance-Related Disorders