There are currently 35 active clinical trials seeking participants for COPD research studies. The states with the highest number of trials for COPD participants are Florida, California, Texas and South Carolina.
Collection of Blood From Healthy Patients, Patients With Benign Disease and Patients With Cancer
NCT05181826
Recruiting
To acquire blood samples from subjects for various purposes, including: i) determining the sensitivity and specificity of select DNA methylation markers for the detection of various types of cancer, ii) identifying benign conditions that may induce false positive or false negative results, and iii) defining the effects of potential interfering substances, such as chemotherapy drugs.
Gender:
All
Ages:
18 years and above
Trial Updated:
06/13/2024
Locations: Torrance Memorial Physician Network - Cancer Care, Redondo Beach, California +6 locations
Conditions: Cancer, Liver Cirrhosis, Chronic Hepatitis, Hepatitis B, Hepatitis C, Diabetes, COPD
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Hyperpolarized 129Xe MR Imaging of Lung Function in Healthy Volunteers and Subjects With Pulmonary Disease
NCT04624490
Recruiting
The purpose of this study is to develop and evaluate the usefulness of hyperpolarized (HP) 129Xe gas MRI for regional assessment of pulmonary function.
Gender:
All
Ages:
3 years and above
Trial Updated:
06/07/2024
Locations: University of Kansas Medical Center, Kansas City, Kansas
Conditions: Asthma, COPD, Interstitial Lung Disease, Cystic Fibrosis, Pulmonary Hypertension, Pulmonary Infection, Other Lung Disease
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The Effect of Interval Exercise on Functional Outcomes in Veterans With COPD and OSA
NCT05254431
Recruiting
The term "Overlap Syndrome" (OS) is used to describe the presence of both chronic obstructive pulmonary disease (COPD) and obstructive sleep apnea (OSA) in a single patient. Due to premature aging, patients with OS are prone to developing functional decline up to 20 years earlier than the general population. The International Classification of Functioning, Disability and Health (ICF) evaluates functional status in chronic pulmonary disease globally in 5 domains. The investigators propose to stud... Read More
Gender:
All
Ages:
All
Trial Updated:
05/15/2024
Locations: Salem VA Medical Center, Salem, VA, Salem, Virginia
Conditions: COPD, OSA
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The Reducing REVISITS Study: A Cluster RCT
NCT05568043
Recruiting
This type II hybrid effectiveness-implementation trial will concurrently study the comparative effectiveness of virtual vs. in-person COPD care transition programs implemented via virtual mentored implementation approaches with and without co-design methods. The investigators will enroll up to 24 randomized sites (with a goal minimum of 16 sites) to: Deliver the COPD programs implemented via mentored support in collaboration with SHM Center for Quality Improvement. Compare the effectiveness an... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/06/2024
Locations: University of Chicago, Chicago, Illinois
Conditions: COPD, COPD Exacerbation Acute
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High Flow vs Conventional Oxygen in Head and Neck Surgery
NCT05362526
Recruiting
Patients undergoing major head and neck surgery are at risk for postoperative pulmonary complications. The goal of this randomized clinical trial is to evaluate the effectiveness of high flow heated humidified oxygen at preventing postoperative pulmonary complications after major head and neck surgery, when compared to conventional oxygen therapy (aerosol cool mist).
Gender:
All
Ages:
Between 18 years and 100 years
Trial Updated:
05/03/2024
Locations: University of Florida, Jacksonville, Florida
Conditions: Pulmonary Disease, COPD
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Tissue Repository Providing Annotated Biospecimens for Approved Investigator-directed Biomedical Research Initiatives
NCT05635266
Recruiting
To collect, preserve, and/or distribute annotated biospecimens and associated medical data to institutionally approved, investigator-directed biomedical research to discover and develop new treatments, diagnostics, and preventative methods for specific and complex conditions.
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
05/03/2024
Locations: Sanguine Biosciences, Waltham, Massachusetts
Conditions: Age-Related Macular Degeneration, Allergies, Alpha-Gal Syndrome, Alzheimer Disease, Amyloidosis, Ankylosing Spondylitis, Arthritis, Alopecia Areata, Asthma, Atopic Dermatitis, Autism, Autoimmune Hepatitis, Behcet's Disease, Beta-Thalassemia, Cancer, Celiac Disease, Kidney Diseases, COPD, Crohn Disease, Cystic Fibrosis, Diabetes, Dravet Syndrome, DMD, Fibromyalgia, Graves Disease, Thyroid Diseases, Hepatitis, Hidradenitis Suppurativa, ITP, Leukemia, ALS, Lupus or SLE, Lymphoma, Multiple Sclerosis, Myasthenia Gravis, Heart Diseases, Parkinson Disease, Pemphigus Vulgaris, Cirrhosis, Psoriasis, Schizophrenia, Scleroderma, Sickle Cell Disease, Stroke, Ulcerative Colitis, Vasculitis, Vitiligo
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Accessing Mobility Using Wearable Sensors
NCT04306588
Recruiting
This study will examine whether wearable sensors can be used to track changes in cognitive-motor performance in response to a disease or an intervention. The investigators specific aims are twofold, first aim to explore whether and how a clinical condition such as Chronic obstructive pulmonary disease (COPD) or Congestive Heart Failure (CHF) may impact motor-cognitive performance measurable using validated wearable devices (e.g., LEGSys, BalanSENS, and Frailty Meter). Second, the investigators... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
04/19/2024
Locations: Michael E. DeBakey Veterans Affairs Medical Center, Houston, Texas
Conditions: COPD, Pulmonary Disease, Pulmonary Restrictive Disease, Congestive Heart Failure, Cardiovascular Diseases
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Effect of Switching From Cigarette Smoking to THS on Disease Progression in Mild to Moderate COPD Subjects With Chronic Bronchitis Symptoms.
NCT05569005
Recruiting
The purpose of this study is to demonstrate the slowing of the disease progression including the improvement of Chronic Obstructive Pulmonary Disease (COPD) symptoms in smoking subjects with mild to moderate COPD and a history of chronic bronchitis symptoms (sputum and cough) who switch to the Tobacco Heating System (THS) as compared to those who continue to smoke cigarettes.
Gender:
All
Ages:
Between 35 years and 65 years
Trial Updated:
04/19/2024
Locations: US49; Clinical Research of Brandon LLC, Brandon, Florida +169 locations
Conditions: COPD, Smoking, Tobacco Use
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A Study Comparing Efficacy, Safety and Tolerability of the Fixed Dose Triple Combination CHF 5993 With the Fixed Dose Dual Combination CHF 1535 in Subjects With COPD
NCT04320342
Recruiting
The purpose of this study is to compare CHF 5993 with CHF 1535 in improving lung function, reducing moderate and severe COPD exacerbations, and other clinical efficacy and safety outcomes in the target subject population.
Gender:
All
Ages:
40 years and above
Trial Updated:
04/17/2024
Locations: Chiesi Clinical Trial Site 840350, Birmingham, Alabama +396 locations
Conditions: COPD, COPD Exacerbation
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Responses to Live Attenuated Influenza Virus (LAIV) in Chronic Obstructive Pulmonary Disease (COPD)
NCT04901455
Recruiting
This study will determine the functional status of the nasal immune environment with LAIV exposure in COPD persons with frequent exacerbations (defined as individuals with two or more episodes of worsening in COPD symptoms requiring treatment with antibiotics and/or steroids in the prior 12 months) and COPD persons without frequent exacerbations to determine acute exacerbation of COPD (AECOPD)-associated dysfunction in a) cytokines and immune effector cells of the nasal mucosa and b) viral repli... Read More
Gender:
All
Ages:
40 years and above
Trial Updated:
04/11/2024
Locations: Eastowne Medical Office Building, Chapel Hill, North Carolina
Conditions: COPD
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Effect of Ensifentrine on Sputum Markers of Inflammation in COPD
NCT05270525
Recruiting
This is a randomized, double-blind, placebo-controlled, two-period cross-over study of nebulized ensifentrine (3 mg) or placebo administered BID for two 8-week Treatment Periods. All participants with receive both ensifentrine and placebo during participation. There are 7 in-clinic visits over a total duration of up to 24 weeks participation.
Gender:
All
Ages:
Between 40 years and 80 years
Trial Updated:
04/05/2024
Locations: University of Alabama at Birmingham, Birmingham, Alabama +1 locations
Conditions: COPD
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Impairments That Affect Correct Inhaler Use in COPD
NCT06135324
Recruiting
INHALE is a one-year, multi-site observational research study funded by Viatris, with two aims: Determine the prevalence of both cognitive impairment and impaired manual dexterity in stable out-patients with chronic obstructive pulmonary disease (COPD). Assess the relationship of cognitive impairment and impaired manual dexterity with patient errors using current pMDIs, SMIs and/or DPIs.
Gender:
All
Ages:
Between 60 years and 90 years
Trial Updated:
03/21/2024
Locations: University of Alabama at Birmingham - Lung Health Center, Birmingham, Alabama +3 locations
Conditions: COPD
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