New Jersey is currently home to 1665 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including New Brunswick, Hackensack, Newark and Morristown. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Fabry Disease Registry & Pregnancy Sub-registry
NCT00196742
Recruiting
The Fabry Registry is an ongoing, international multi-center, strictly observational program that tracks the routine clinical outcomes for patients with Fabry disease, irrespective of treatment status. No experimental intervention is involved; patients in the Registry undergo clinical assessments and receive care as determined by the patient's treating physician. The primary objectives of the Registry are: * To enhance the understanding of the variability, progression, and natural history of F... Read More
Gender:
ALL
Ages:
All
Trial Updated:
11/19/2024
Locations: Cooper Health Center- Site Number : 840098, Camden, New Jersey
Conditions: Fabry Disease
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Mucopolysaccharidosis I (MPS I) Registry
NCT00144794
Recruiting
The Mucopolysaccharidosis I (MPS I) Registry is an ongoing, observational database that tracks the outcomes of patients with MPS I. The data collected by the MPS I Registry will provide information to better characterize the natural history and progression of MPS I as well as the clinical responses of patients receiving enzyme replacement therapy, such as Aldurazyme (Recombinant Human Alpha-L-Iduronidase), or other treatment modalities. The objectives of the Registry are: * To evaluate the lon... Read More
Gender:
ALL
Ages:
All
Trial Updated:
11/19/2024
Locations: Joseph M. Sanzari Children's Hospital- Site Number : 840101, Hackensack, New Jersey
Conditions: Mucopolysaccharidosis I (MPS I)
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The Effect of Articulatory Gestures on Early Literacy Skills in 4-year Olds
NCT06504264
Recruiting
This study will use an experimental design to explore if articulatory gestures (with letters and phonemic awareness training) enhance early literacy skills more than general mouth awareness training (with letters and phonemic awareness training) or letter/phonemic awareness training alone.
Gender:
ALL
Ages:
Between 48 months and 59 months
Trial Updated:
11/18/2024
Locations: Montclair State University, Montclair, New Jersey
Conditions: Early Literacy, Articulatory Gestures, Phonemic Awareness
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Student Exercise and Sleep Timing Study - Part 2
NCT06336590
Recruiting
The purpose of this study is to examine the effects of a morning exercise intervention on sleep (quality and duration), mood (positive affect, anxiety, depression, anger), stress and productivity among undergraduate students (18-23 years) evening-exercisers with poor self-reported sleep quality. Aim 1. Compared to the control condition, evening-exercisers prescribed morning exercise will exhibit improved sleep quality (increased efficiency, decreased fragmentation) and increased sleep duration.... Read More
Gender:
ALL
Ages:
Between 18 years and 23 years
Trial Updated:
11/18/2024
Locations: College Avenue Gym, New Brunswick, New Jersey
Conditions: Sleep, Mood, Stress
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Transfusion Requirements in Younger Patients Undergoing Cardiac Surgery
NCT04754022
Recruiting
TRICS-IV is an international, multi-centre, open-label randomized controlled trial of two commonly used transfusion strategies in moderate to high risk patients who are 65 years of age or younger undergoing cardiac surgery on cardiopulmonary bypass, using a superiority trial design.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
11/18/2024
Locations: The Cooper Health System, Camden, New Jersey
Conditions: Disorder, Heart, Postoperative, Cardiac Surgery
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Identify the Optimal TMS Pulse Protocol to Modulate Reward Activity
NCT06695884
Recruiting
Our primary goal will be to identify the optimal pulse protocol by systematically measuring the efficacy of various theta burst stimulation and repetitive rTMS protocols to increase and decrease the reward positivity in dependent smokers. Our secondary objective will be to measure the protocols' effectiveness to increase decision-making capacity using the probabilistic selection task (PST). Our third objective will be to specifically assess whether the TMS targets has a differential impact on st... Read More
Gender:
ALL
Ages:
Between 18 years and 55 years
Trial Updated:
11/15/2024
Locations: Rutgers University - Newark, Newark, New Jersey
Conditions: Nicotine Use Disorder
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Pedal Pump and Leg Lymphedema
NCT06235463
Recruiting
Chronic lymphedema in the lower extremities is a common problem found in older adults that can result in cellulitis, poor wound healing, venous stasis ulcers, and other comorbidities. Compressive therapies are the present gold standard for the manual treatment of lymphedema in the lower extremities. However, the benefits of these compressive therapies are modest, and they are not well tolerated by older adults. An alternative manual treatment is the osteopathic pedal pump, an osteopathic manipul... Read More
Gender:
ALL
Ages:
Between 55 years and 100 years
Trial Updated:
11/14/2024
Locations: Rowan University School of Osteopathic Medicine, Stratford, New Jersey
Conditions: Lymphedema
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Pivotal-Safety and Therapeutic Measures of tDCS in Patients With Refractory Focal Epilepsy
NCT04770337
Recruiting
This is a multiple site, randomized, double blinded parallel-group controlled study. The purpose of this study is to evaluate efficacy, safety, and tolerability of repeated, daily sessions with the STARSTIM device, which delivers transcranial cathodal direct current stimulation (tDCS). Subjects will be treated with STARTSTIM or sham device for 10 sessions over a 2-week period. The subjects will be followed for an additional 10 weeks post treatment. Quality of Life questionnaires and adverse even... Read More
Gender:
ALL
Ages:
9 years and above
Trial Updated:
11/14/2024
Locations: Robert Wood Johnson Medical School (Rutgers), New Brunswick, New Jersey
Conditions: Refractory Epilepsy, Focal Seizure, Seizures, Focal, Seizures, Epilepsy in Children, Epilepsy, Epilepsy, Tonic-Clonic
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Pharmacokinetics, Pharmacodynamics and Safety of Epeleuton in Patients with Sickle Cell Disease
NCT05861453
Recruiting
To assess the pharmacokinetics, pharmacodynamics and safety of Epeleuton capsules in adult SCD patients who are aged ≥18 years.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/13/2024
Locations: Robert Wood Johnson Medical School Rutgers, New Brunswick, New Jersey
Conditions: Sickle Cell Disease
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Internet Assisted Career-Oriented Soft-skills Training for Transition Age Youth with Mental Health Conditions
NCT05766280
Recruiting
The purpose of this study is to evaluate the effectiveness of an internet- assisted Career-Oriented Work-Related Soft-skills Training (iCareer) intervention, infused with cognitive behavioral therapy, targeting individuals ages 16-24 with mental health conditions, to improve employment outcomes. The overall objective is to help transition-age youth (TAY) with psychiatric disabilities achieve optimal employment outcomes as part of successful transition to adulthood. Findings will have implication... Read More
Gender:
ALL
Ages:
Between 16 years and 24 years
Trial Updated:
11/12/2024
Locations: Rutgers Univeristy, Newark- Office of Disability Services, Newark, New Jersey
Conditions: Mental Health Wellness 1, Mental Health Wellness 2, Occupational Problems
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Identify the Optimal TMS Target to Modulate Reward Activity
NCT05766254
Recruiting
Our primary goal will be to identify the optimal prefrontal-cingulate target by systematically measuring the efficacy of various image-based targeting techniques to increase the reward positivity using the 10-Hz TMS protocol in dependent smokers. Our secondary objective will be to measure the targets' effectiveness to increase decision-making capacity using the probabilistic selection task (PST). Our third objective will be to specifically assess whether the TMS targets has a differential impact... Read More
Gender:
ALL
Ages:
Between 18 years and 55 years
Trial Updated:
11/12/2024
Locations: Rutgers University - Newark, Newark, New Jersey
Conditions: Nicotine Use Disorder
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Characterization of the Temporo-masseteric Nerve Block (TMNB) in Healthy Subjects
NCT05507164
Recruiting
The proposed pilot study is aimed at preliminary characterization of the TMNB injection in 20 healthy volunteers. Assessment of bite-force distribution and surface electromyographic activity of the temporalis and the masseter muscles, at rest and clench, before and after unilateral TMNB injection, will be the primary outcome measures. Post-injection assessments will be performed at 30 minutes, 2 hours, and 2 weeks after the injection. Participants will be surveyed regarding their experience rece... Read More
Gender:
ALL
Ages:
Between 18 years and 64 years
Trial Updated:
11/12/2024
Locations: Rutgers School of Dental Medicine, Newark, New Jersey
Conditions: Occlusion
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