New Jersey is currently home to 1712 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including New Brunswick, Hackensack, Newark and Morristown. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
CGX1321 in Subjects With Advanced Solid Tumors and CGX1321 With Pembrolizumab or Encorafenib + Cetuximab in Subjects With Advanced GI Tumors (Keynote 596)
NCT02675946
Recruiting
This is a multicenter, open-label study conducted in two phases: Phase 1 consisting of a CGX1321 Single Agent Dose Escalation Phase in solid tumors, CGX1321 Single Agent Dose Expansion Phase in GI tumors and Roll-over Cohort of CGX1321 and pembrolizumab in subjects who have progressed on single agent CGX1321 and Phase 1b consisting of CGX1321 in combination with pembrolizumab in colorectal tumors and CGX1321 in combination with encorafenib + cetuximab in BRAFV600E mutated colorectal tumors. Both... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
01/11/2022
Locations: Summit Medical Group, Florham Park, New Jersey
Conditions: Solid Tumors, GI Cancer
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Early Feasibility Study of the Cardiac Implants Percutaneous Ring Annuloplasty System
NCT04890821
Recruiting
An early feasibility study to evaluate the safety and performance of 1) the transcatheter delivery and implantation of the Cardiac Implants (CI) annuloplasty ring and 2) the adjustment of the ring approximately 90 days following implantation in patients suffering from ≥ moderate functional tricuspid regurgitation (FTR).
Gender:
All
Ages:
18 years and above
Trial Updated:
11/18/2021
Locations: Hackensack University Medical Center, Hackensack, New Jersey
Conditions: Tricuspid Regurgitation Functional
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Comparison of Two Web-Based Education/Support Programs for Partner Caregivers of People With Spinal Cord Injury
NCT04827095
Recruiting
The purpose of this research study is to compare the effect of two different types of education and support programs for partner caregivers of people with spinal cord injury (SCI).
Gender:
All
Ages:
18 years and above
Trial Updated:
11/11/2021
Locations: Kessler Foundation, West Orange, New Jersey
Conditions: Spinal Cord Injuries, Spinal Cord Diseases
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Variability in Transcranial Doppler Technique in Neuro-Critical Care Patients
NCT04583163
Recruiting
This study aims to determine the inter- and intra-variability of Transcranial Doppler (TCD) ultrasound in neuro-critical care patients who are planned for consecutive daily TCD evaluations.
Gender:
All
Ages:
18 years and above
Trial Updated:
11/08/2021
Locations: Hackensack University Medical Center, Hackensack, New Jersey
Conditions: Cerebral Aneurysm, Stroke, Vasospasm, Cerebral, Subarachnoid Hemorrhage, Aneurysmal, Aneurysmal Subarachnoid Hemorrhage, Cerebral Ischemia
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Longitudinal Performance of Epi proColon
NCT03218423
Recruiting
This study will evaluate longitudinal performance of Epi proColon with respect to test positivity, longitudinal adherence to Epi proColon screening, adherence to follow-up colonoscopy and diagnostic yield, as well as assay failure rates.
Gender:
All
Ages:
Between 50 years and 74 years
Trial Updated:
10/29/2021
Locations: Rutgers University Hospital, New Brunswick, New Jersey
Conditions: Colorectal Cancer, Colorectal Neoplasms
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The Impact of Two Different Physical Therapy Programs in the Rehabilitation of Patients Undergoing Anterior Approach Hip Replacement Surgery
NCT04492462
Recruiting
This study will look to determine two different types of physical therapy regimens in patients who undergo anterior total hip replacement. We will compare the results of two groups. The first group, the "Formal Physical Therapy" group, will undergo standard physical therapy following their surgery. They will see a physical therapist in a physical therapy office after their surgery. Here, the therapist will work with the patient to strengthen muscles and improve their walking. The second group, t... Read More
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
09/14/2021
Locations: University Orthopaedic Associates, Somerset, New Jersey
Conditions: Hip Arthritis, Total Hip Arthroplasty
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Myeloma-Developing Regimens Using Genomics (MyDRUG)
NCT03732703
Recruiting
The MyDRUG study is a type of Precision Medicine trial to treat patients with drugs targeted to affect specific genes that are mutated as part of the disease. Mutations in genes can lead to uncontrolled cell growth and cancer. Patients with a greater than 25% mutation to any of the following genes; CDKN2C, FGFR3, KRAS, NRAS, BRAF V600E, IDH2 or T(11;14) can be enrolled to one of the treatment arms. These arms have treatments specifically directed to the mutated genes. Patients that do not have a... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
09/09/2021
Locations: Hackensack University Medical Center, Hackensack, New Jersey
Conditions: Relapsed Refractory Multiple Myeloma
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Comparison Studies Comparing Hemodynamic Parameters Provided by the Caretaker Against Respective Gold Standard References
NCT05035719
Recruiting
Comparison studies comparing hemodynamic parameters provided by the Caretaker against respective Gold Standard references.
Gender:
All
Ages:
18 years and above
Trial Updated:
09/01/2021
Locations: Cooper University Hospital, Camden, New Jersey
Conditions: Cardiac Output, Low
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Early Mobilization Following Volar Locking Plate Fixation of Distal Radius Fractures
NCT05033938
Recruiting
The overall purpose of this study is to establish the utility of early mobilization in improving patient satisfaction following plate and screw fixation of wrist fractures. Subjects will have objective range of motion data collected and subjective survey data collected at 2 weeks, 6 weeks, 3 months, and 1 year after being randomized either to an early mobilization group that receives a removable wrist splint or a late mobilization group that is placed in a splint for 2 weeks post-operatively. Th... Read More
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
08/27/2021
Locations: University Orthopedics Associates, Somerset, New Jersey
Conditions: Distal Radius Fracture
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The EndRAD Trial: Eliminating Total Body Irradiation (TBI) for NGS-MRD Negative Children, Adolescents, and Young Adults With B-ALL
NCT03509961
Recruiting
This study will evaluate the use of non- TBI (total body irradiation) conditioning for B-ALL patients with low risk of relapse as defined by absence of NGS-MRD (next generation sequencing minimal residual disease) before receiving a hematopoietic cell transplant (HCT). Patients diagnosed with B-ALL who are candidates for HCT will be screened by NGS-MRD on a test of bone marrow done before the HCT. Subjects who are pre-HCT NGS-MRD negative will be eligible to receive a non-TBI conditioning regime... Read More
Gender:
All
Ages:
Between 1 year and 25 years
Trial Updated:
08/20/2021
Locations: Hackensack University Medical Center, Hackensack, New Jersey
Conditions: B-cell Acute Lymphoblastic Leukemia
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Multi-Center Study to Evaluate the Efficacy and Safety of Sildenafil Cream (3.6%) in Premenopausal Patients With Female Sexual Arousal Disorder
NCT04948151
Recruiting
This study is looking to minimize side effects, while maintaining and potentially improving the therapeutic benefit to patients suffering from Female Sexual Arousal Disorder by providing a topical preparation of Sildenafil locally to the vulvar-vaginal tissue.
Gender:
Female
Ages:
21 years and above
Trial Updated:
06/24/2021
Locations: Women's Health Research Center, Lawrenceville, New Jersey
Conditions: Female Sexual Arousal Disorder
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Evaluation of a Novel Female Hygiene Device for Postcoital Discomfort
NCT04885556
Recruiting
Previous research has shown that semen deposition in the vagina after intercourse leads to dripping, discomfort, and vaginal odor. This study is evaluating a hygiene device designed to be inserted into the vagina after intercourse to absorb semen deposited into the vaginal canal to determine if there is a reduction in dripping and odor, and to determine the amount of fluids absorbed.
Gender:
Female
Ages:
Between 25 years and 50 years
Trial Updated:
05/08/2021
Locations: The Center for Specialized Women's Health, division of Garden State Urology, Denville, New Jersey
Conditions: Vaginal Discharge, Dyspareunia, Female Sexual Dysfunction, Vaginitis, Bacterial Vaginoses
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