New Jersey is currently home to 1696 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including New Brunswick, Hackensack, Newark and Morristown. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Internet Assisted Career-Oriented Soft-skills Training for Transition Age Youth with Mental Health Conditions
NCT05766280
Recruiting
The purpose of this study is to evaluate the effectiveness of an internet- assisted Career-Oriented Work-Related Soft-skills Training (iCareer) intervention, infused with cognitive behavioral therapy, targeting individuals ages 16-24 with mental health conditions, to improve employment outcomes. The overall objective is to help transition-age youth (TAY) with psychiatric disabilities achieve optimal employment outcomes as part of successful transition to adulthood. Findings will have implication... Read More
Gender:
ALL
Ages:
Between 16 years and 24 years
Trial Updated:
11/12/2024
Locations: Rutgers Univeristy, Newark- Office of Disability Services, Newark, New Jersey
Conditions: Mental Health Wellness 1, Mental Health Wellness 2, Occupational Problems
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Identify the Optimal TMS Target to Modulate Reward Activity
NCT05766254
Recruiting
Our primary goal will be to identify the optimal prefrontal-cingulate target by systematically measuring the efficacy of various image-based targeting techniques to increase the reward positivity using the 10-Hz TMS protocol in dependent smokers. Our secondary objective will be to measure the targets' effectiveness to increase decision-making capacity using the probabilistic selection task (PST). Our third objective will be to specifically assess whether the TMS targets has a differential impact... Read More
Gender:
ALL
Ages:
Between 18 years and 55 years
Trial Updated:
11/12/2024
Locations: Rutgers University - Newark, Newark, New Jersey
Conditions: Nicotine Use Disorder
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Characterization of the Temporo-masseteric Nerve Block (TMNB) in Healthy Subjects
NCT05507164
Recruiting
The proposed pilot study is aimed at preliminary characterization of the TMNB injection in 20 healthy volunteers. Assessment of bite-force distribution and surface electromyographic activity of the temporalis and the masseter muscles, at rest and clench, before and after unilateral TMNB injection, will be the primary outcome measures. Post-injection assessments will be performed at 30 minutes, 2 hours, and 2 weeks after the injection. Participants will be surveyed regarding their experience rece... Read More
Gender:
ALL
Ages:
Between 18 years and 64 years
Trial Updated:
11/12/2024
Locations: Rutgers School of Dental Medicine, Newark, New Jersey
Conditions: Occlusion
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Microbiome Derived Metabolism and Pharmacokinetics
NCT05065671
Recruiting
The investigators will perform single-dose pharmacokinetic (PK) studies in humans following administration of drugs with known microbiome derived metabolism (MDM) in parallel with preclinical studies. By directly comparing laboratory measurements to clinical results, the investigators will be able to confirm the relevance of MDM in vivo, create microbiome-dependent PK profiles of the MDM positive drugs, and establish methodology to capture the contribution of MDM to inter-individual variability... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
11/12/2024
Locations: Robert Wood Johnson University Hospital Somerset, Somerville, New Jersey
Conditions: Microbial Colonization
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Immunoglobulin G Therapy Dose Optimization
NCT04818177
Recruiting
The overall goal of this proposal is to investigate effects of obesity on pharmacokinetics of immunoglobulin G (IgG) and to develop strategies for optimization of dosing of IgG in obese patients. There is an ongoing debate regarding the most appropriate dosing of IgG formulations in obese patients. Obesity poses significant health risks; and evidence supporting dosing strategies of IgG in obese patients is inadequate. Some of the adverse reactions have been attributed to a relative overdosing in... Read More
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
11/12/2024
Locations: Robert Wood Johnson University Hospital Somerset, Somerville, New Jersey
Conditions: Obesity, Immune Deficiency
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A Study of Sotorasib in People with Non-Small Cell Lung Cancer
NCT06582771
Recruiting
The researchers are doing this study to see if sotorasib is a safe and effective treatment for people with advanced non-small cell lung cancer (NSCLC) with a KRAS G12C mutation who have not received treatment for their cancer since it became advanced. (Participants have not received a "first-line therapy" since their cancer became advanced.)
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/11/2024
Locations: Memorial Sloan Kettering Basking Ridge (Limited Protocol Activities), Basking Ridge, New Jersey
Conditions: Non Small Lung Cancer
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Tamibarotene Plus Azacitidine in Participants With Newly Diagnosed RARA-positive Higher-Risk Myelodysplastic Syndrome
NCT04797780
Recruiting
This study compares the efficacy of Tamibarotene in combination with azacitidine to azacitidine in combination with placebo in participants who are Retinoic Acid Receptor Alpha (RARA) positive, and newly diagnosed with higher-risk myelodysplastic syndrome (HR-MDS), and who have not received treatment for this diagnosis. The primary goal of the study is to compare the complete remission rate between the two treatment arms.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/08/2024
Locations: Morristown Medical Center- Atlantic Hematology Oncology, Morristown, New Jersey
Conditions: Myelodysplastic Syndromes
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ONC-392 Plus Lutetium Lu 177 Vipivotide Tetraxetan in Patients With mCRPC
NCT05682443
Recruiting
In this Phase 2 study, mCRPC patients with PSMA positive scans who progressed on prior ARTA and up to 2 lines of taxanes, and are naïve to lutetium Lu 177 vipivotide tetraxetan, will be enrolled. The study is open-label, randomized with active control, multi-center study.
Gender:
MALE
Ages:
18 years and above
Trial Updated:
11/01/2024
Locations: Rutgers Cancer Institute of New Jersey - 1614, New Brunswick, New Jersey
Conditions: Metastatic Castration-resistant Prostate Cancer
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REvascularization CHoices Among Under-Represented Groups Evaluation: The RECHARGE Trial - Minorities
NCT06399705
Recruiting
This is a research study in minorities to compare the outcomes of two procedures that restore blood flow to the arteries of the heart. In one procedure the blockages are ballooned and then stented with a small wire mesh tube through a small incision in the wrist or the groin. The other procedure is an open-heart operation in which healthy blood vessels from inside the chest, leg, and/or forearm are used to "bypass" the blockages (like a detour). Outcomes will be measured by comparing survival an... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/30/2024
Locations: Englewood Hospital, Englewood, New Jersey
Conditions: Coronary Artery Disease
Register for Updates
REvascularization CHoices Among Under-Represented Groups Evaluation: The RECHARGE Trial - Women
NCT06399692
Recruiting
This is a research study in women to compare the outcomes of two procedures that restore blood flow to the arteries of the heart. In one procedure the blockages are ballooned and then stented with a small wire mesh tube through a small incision in the wrist or the groin. The other procedure is an open-heart operation in which healthy blood vessels from inside the chest, leg, and/or forearm are used to "bypass" the blockages (like a detour). Outcomes will be measured by comparing survival and imp... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/30/2024
Locations: Englewood Hospital, Englewood, New Jersey
Conditions: Coronary Artery Disease
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Pulsed Electromagnetic Field Treatment In Patients With Alzheimer's Disease
NCT05295615
Recruiting
An open label pilot study in mild to moderate AD patients to assess the effects of treatment with ECHS AD pulsed electromagnetic treatment device on disease progression. Enrolled patients will receive active devices. They will treat themselves at home three times a day for 15 minutes over 120 days. Primary end points are the The Alzheimer's Disease Assessment Scale-Cognitive Subscale and the Mini-Mental State Exam. Participants will be followed-up for 9 months post-treatment.
Gender:
ALL
Ages:
Between 50 years and 100 years
Trial Updated:
10/30/2024
Locations: Hackensack Medical Center, Hackensack, New Jersey
Conditions: Alzheimer Disease
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Melatonin for Prevention of Kidney Injury
NCT05084196
Recruiting
This study will evaluate the safety and effectiveness of melatonin for the prevention of antibiotic associated acute kidney injury in hospitalized patients.
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
10/30/2024
Locations: Robert Wood Johnson University Hospital, New Brunswick, New Jersey
Conditions: Acute Kidney Injury, Adverse Drug Event
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