There are currently 283 active clinical trials seeking participants for Cancer research studies. The states with the highest number of trials for Cancer participants are California, Texas, New York and Florida.
Re-Engaging AYA Survivors in Cancer-Related Healthcare
NCT07138040
Recruiting
The goal of this clinical trial is to test the efficacy (how well they work) of different digital interventions that deliver information to adolescent and young adult (AYA) survivors of childhood cancer to promote re-engagement in cancer-related long-term follow-up care (LTFU). The main aims are: * To test the efficacy of adaptive interventions (AIs) that begin with low touch intervention (LTI) as compared to written information (WI) on attending an appointment, and self-reported self-managemen... Read More
Gender:
ALL
Ages:
Between 15 years and 29 years
Trial Updated:
08/15/2025
Locations: Nationwide Children's Hospital, Columbus, Ohio +2 locations
Conditions: Cancer
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Precision Cancer Medicine for Advanced Cancer Through High-throughput Sequencing
NCT02090530
Recruiting
Precision Cancer Medicine for Advanced Cancer Through High-throughput Sequencing
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/04/2025
Locations: Ohio State University Wexner Medical Center, Columbus, Ohio
Conditions: Cancer
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Online Tai Chi Intervention to Promote Smoking Cessation Among Cancer Survivors
NCT05941858
Recruiting
This clinical trial evaluates an online Tai Chi intervention to promote smoking cessation among cancer survivors. Tai chi is a practice that involves a series of slow gentle movements and physical postures, a meditative state of mind, and controlled breathing. It is a gentle form of exercise that can be done while sitting or standing and does not involve any medications or medical procedures. Tai chi originated as an ancient martial art in China. Over the years, it has become more focused on hea... Read More
Gender:
ALL
Ages:
21 years and above
Trial Updated:
03/24/2025
Locations: Ohio State University Comprehensive Cancer Center, Columbus, Ohio
Conditions: Cancer
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Promoting Access, Resources and Treatment Through Novel and Equitable Solutions for Cancer Care
NCT06481774
Recruiting
The purpose of this research is to evaluate a novel, integrated approach to providing navigation services to improve cancer outcomes and quality of life.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/24/2024
Locations: Case Comprehensive Cancer Center, Cleveland, Ohio
Conditions: Cancer
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Lattice Radiotherapy for Dose-Escalated Palliation of Bulky Tumors
NCT06416007
Recruiting
The purpose of this research study is to determine if lattice radiation therapy (LRT) will provide better treatment for bulky (large) tumors than current standard of care radiotherapy.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/20/2024
Locations: University of Cincinnati Medical Center, Cincinnati, Ohio
Conditions: Cancer, Metastatic Cancer, Locally Advanced, Locally Advanced Solid Tumor, Locally Advanced Carcinoma
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Evaluation of Late Effects and Natural History of Disease in Patients Treated With Radiotherapy
NCT00026650
Recruiting
BACKGROUND * This protocol acknowledges that it is in the interest of the NIH and ROB, as well as our participants, to continue to follow those who have been treated with radiotherapy at ROB and are not otherwise eligible for current active research protocols. * It also provides a mechanism for the correlation and interpretation of disparate data for research into the long term side effects and outcomes for a variety of disease entities and treatments, such as combined modality treatment, MoAb,... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/22/2025
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Cancer
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A Phase I/II Study of Zotiraciclib for Recurrent Malignant Gliomas With Isocitrate Dehydrogenase 1 or 2 (IDH1 or IDH2) Mutations
NCT05588141
Recruiting
Background: Diffuse gliomas are tumors that affect the brain and spinal cord. Gliomas that develop in people with certain gene mutations (IDH1 or IDH2) are especially aggressive. Better treatments are needed. Objective: To see if a study drug (zotiraciclib) is effective in people with recurrent diffuse gliomas who have IDH1 or IDH2 mutations. Eligibility: People aged 15 years and older with diffuse gliomas that returned after treatment. They must also have mutations in the IDH1 or IDH2 gene... Read More
Gender:
ALL
Ages:
15 years and above
Trial Updated:
08/22/2025
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Brain Tumor, Cancer
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DASH INtervention to INvestigate the Gut
NCT04538482
Recruiting
The study investigators will recruit a generally healthy sample of 112 black and white adults from Birmingham, AL to participate in a 28-day randomized, controlled feeding study. Participants will be randomized to receive either the DASH diet or a standard American diet. All meals will be provided by the study. Fecal samples will be collected at multiple time points before, during, and after the dietary intervention and will be analyzed using PCR to amplify the V4 region of the 16S rRNA gene and... Read More
Gender:
ALL
Ages:
Between 19 years and 65 years
Trial Updated:
08/20/2025
Locations: Moffitt Cancer Center, Tampa, Florida
Conditions: Microbiota, Cancer
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A Multilevel Approach to Connecting Underrepresented Populations to Clinical Trials
NCT05655494
Recruiting
The purpose of this study is to pilot test and evaluate an existing tailored ALEX (Agent Leveraging Empathy for eXams) Research Portal to navigate Black and Hispanic adult cancer patients and their family members through referral to cancer clinical trials.
Gender:
ALL
Ages:
Between 18 years and 100 years
Trial Updated:
08/19/2025
Locations: University of Florida, Gainesville, Florida +2 locations
Conditions: Cancer
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Prospective Study to Assess a Diagnostic Aid for Cancer
NCT07046260
Recruiting
The primary objective of this study is to evaluate the performance of a blood-based diagnostic aid test for cancer detection in individuals presenting with symptoms, signs, or findings that raise clinical suspicion for cancer.
Gender:
ALL
Ages:
45 years and above
Trial Updated:
08/18/2025
Locations: Palomar Health, Poway, California +24 locations
Conditions: Cancer
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A Study to Learn About Study Medicine ALTA2618 in Adults With AKT1 E17K-Mutant Solid Tumors
NCT06533059
Recruiting
The purpose of this study is to characterize the safety and tolerability of ALTA2618 in adults with AKT1 E17K-mutant advanced solid tumors.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/15/2025
Locations: Research Site, La Jolla, California +45 locations
Conditions: Cancer, Breast Cancer, Endometrial Cancer, Metastatic Cancer, Advanced Solid Tumor
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Optimizing Care for Cancer Survivors With Depression: Project 3
NCT06930729
Recruiting
The purpose of this research study is to evaluate different depression treatment approaches among cancer survivors. A cancer survivor is defined as anyone who is living and has been diagnosed with cancer. Participants will be randomly assigned to either receive a mobile app for depression treatment, called "Moodivate", or to receive telehealth depression treatment sessions. Approximately 2/3 of participants enrolled will receive the mobile app and the remaining 1/3 will receive depression treat... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/15/2025
Locations: Medical University of South Carolina, Charleston, South Carolina
Conditions: Cancer, Depression
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