There are currently 278 active clinical trials seeking participants for Cancer research studies. The states with the highest number of trials for Cancer participants are California, Texas, New York and Florida.
COBRA: Cancer, Older Adults, Balance and Resistance Activities
NCT07011862
Recruiting
The purpose of this study is to find out whether an 8-week digital health promotion program called COBRA is a safe and practical (feasible) option for older adults with cancer/OAC.
Gender:
ALL
Ages:
65 years and above
Trial Updated:
06/02/2025
Locations: Memorial Sloan Kettering Monmouth (Consent only), Middletown, New Jersey +5 locations
Conditions: Primary Cancer, Metastatic Cancer, Cancer
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A Phase 2 Clinical Trial Evaluating the Efficacy and Safety of Dual Immune Checkpoint Inhibition With Anti-PD-L1 (Atezolizumab) and Anti-TIGIT (Tiragolumab) in Cancer of Unknown Primary
NCT06754501
Recruiting
The goal of this clinical research study is to learn if the combination of atezolizumab and tiragolumab can help to control cancers of unknown primary. The safety and effects of this drug combination will also be studied
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/01/2025
Locations: The University of Texas M. D. Anderson Cancer Center, Houston, Texas
Conditions: Cancer
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Ultralow Dose PET Imaging of 18F-FDG Uptake
NCT06956391
Recruiting
The goal of this clinical trial is to evaluate an investigational ultralow dose PET imaging technique for cancer detection and monitoring. The main question it aims to answer is: Can the investigators optimize the timing, scan duration, and image reconstruction to reduce the radiation dose 10-100 fold of the current clinical standard? Participants will be injected with a radioactive tracer called 18F-FDG and be imaged on a new type of high-sensitivity PET scanner for up to 3 hours.
Gender:
ALL
Ages:
Between 18 years and 120 years
Trial Updated:
06/01/2025
Locations: Nuclear Imaging Institute, Englewood, New Jersey
Conditions: Healthy Volunteer, Cancer
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Falcon Real World Evidence Registry
NCT06589310
Recruiting
This is a multi-site registry of patients receiving the Exact Sciences Multicancer Early Detection (MCED) test.
Gender:
ALL
Ages:
Between 50 years and 80 years
Trial Updated:
05/30/2025
Locations: Endeavor Health, Evanston, Illinois +1 locations
Conditions: Cancer
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A Study to Learn About Study Medicine ALTA2618 in Adults With AKT1 E17K-Mutant Solid Tumors
NCT06533059
Recruiting
The purpose of this study is to characterize the safety and tolerability of ALTA2618 in adults with AKT1 E17K-mutant advanced solid tumors.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/29/2025
Locations: Research Site, La Jolla, California +39 locations
Conditions: Cancer, Breast Cancer, Endometrial Cancer, Metastatic Cancer, Advanced Solid Tumor
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Sildenafil to Prevent and Reduce Cancer Related Cognitive Impairment
NCT06800092
Recruiting
This study is examining the effects of standard of care cancer treatment as well as a medication called Sildenafil, on the cancer associated fatigue, cognition and the gut microbiome.
Gender:
FEMALE
Ages:
Between 30 years and 50 years
Trial Updated:
05/27/2025
Locations: The University of Texas Medical Branch, Galveston, Texas
Conditions: Cancer
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Evaluating Microarray Pharmacogenetic Testing in Cancer Patients
NCT06489041
Recruiting
The purpose of this research is to evaluate the impact of a microarray PGx test on prescribing/dosing of drugs and cancer treatments in patients with cancer who are currently eligible for single-gene DPYD testing.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/27/2025
Locations: Atrium Health Levine Cancer, Charlotte, North Carolina
Conditions: Cancer, Gastrointestinal Cancer
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The Gut Microbiome and Immunotherapy Response in Solid Cancers
NCT06050733
Recruiting
The aim of this study is characterize the gastrointestinal microbiomes of patient with solid cancer undergoing standard of care treatment with programmed cell death protein 1 (PD-1) /programmed cell death ligand (PD-L1) blockade.
Gender:
ALL
Ages:
Between 35 years and 75 years
Trial Updated:
05/27/2025
Locations: University of Texas Medical Branch, Galveston, Texas
Conditions: Cancer
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Digital Art Therapy for Young Cancer Survivors
NCT06789666
Recruiting
This is a single-site, single-arm, interventional study assessing the feasibility of the ARTCan Therapy Application (App) and whether it is an acceptable means of administering art therapy to young adult cancer survivors. The ARTCan Therapy App guides participants through a 6-week digital art therapy program. Subjects will participate in weekly art therapy prompts guided by the app and will complete weekly mental health quality of life (MHQoL) surveys during the intervention. In addition, baseli... Read More
Gender:
ALL
Ages:
Between 18 years and 25 years
Trial Updated:
05/22/2025
Locations: Lineberger Comprehensive Cancer Center, Chapel Hill, North Carolina
Conditions: Cancer, Pediatric Cancer, Pediatric Malignancies, Pediatric Sarcoma of Soft Tissue, Adolescent and Young Adult With Brain Cancer
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Preserving Physical Function in Older Adults With Cancer: Impact of an Optimizing Nutrition Intervention Applied Before and After Surgery
NCT05912257
Recruiting
In this pragmatic clinical trial, the investigators will study older Veterans approaching surgery for gastrointestinal or genitourinary cancer who are at high risk for a marked decline in their physical function. The investigators will test a multi-targeted nutrition regimen high in protein and other key nutrients and including resistance exercise, administered 8 weeks prior to surgery and for 24 weeks after discharge from surgery, with the goal of protecting physical function and improving phys... Read More
Gender:
ALL
Ages:
60 years and above
Trial Updated:
05/21/2025
Locations: Durham VA Medical Center, Durham, NC, Durham, North Carolina
Conditions: Cancer
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DISCO: A Patient Intervention to Reduce the Financial Burden of Cancer
NCT04766190
Recruiting
The DISCO App is designed to improve, during the interaction, patient active participation and patient-initiated oncologist treatment cost discussions, and, in the short term, patient's treatment cost knowledge, self-efficacy for managing both cost and physician interactions, referrals, perceived financial toxicity (i.e., distress and material hardship); in turn, these will affect longer-term outcomes of financial toxicity and adherence.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/21/2025
Locations: Barbara Ann Karmanos Cancer Institute, Detroit, Michigan
Conditions: Financial Toxicity, Cancer, Question Prompt List, Breast Cancer, Prostate Cancer
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Communicating Uncertainties Associated With the Benefits and Risks of New Cancer Drugs
NCT06997185
Recruiting
This nationally representative randomized survey of US adults will evaluate the effect of using brief statements to communicate different sources of uncertainty about the benefits and harms of new cancer drugs on participants' decisions and understanding.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/21/2025
Locations: Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, Massachusetts
Conditions: Cancer
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