There are currently 298 active clinical trials seeking participants for Cancer research studies. The states with the highest number of trials for Cancer participants are California, Texas, New York and Florida.
Larotrectinib to Enhance RAI Avidity in Differentiated Thyroid Cancer
NCT05783323
Recruiting
Papillary thyroid cancer (PTC) is the most common form of differentiated thyroid cancer (DTC). The traditional first line treatment for patients with advanced DTC after surgical resection is radioactive iodine (RAI) therapy. However, less than a quarter of patients with lung metastases will achieve a complete response to RAI therapy, and this therapy carries the risk of pulmonary fibrosis and an increasingly recognized risk of secondary malignancies.
Gender:
All
Ages:
Between 2 years and 99 years
Trial Updated:
05/15/2024
Locations: Children's Hospital of Philadelphia, Philadelphia, Pennsylvania
Conditions: Differentiated Thyroid Cancer, Pediatric Cancer, Cancer, Cancer, Thyroid
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Virtual Reality to Promote Relaxation Prior to Simulation
NCT06318338
Recruiting
The purpose of this study is to assess the feasibility of a pre-simulation virtual reality (VR) platform designed to promote relaxation for cancer patients planned for radiation therapy (RT).
Gender:
All
Ages:
18 years and above
Trial Updated:
05/14/2024
Locations: Perelman Center for Advanced Medicine, Philadelphia, Pennsylvania
Conditions: Cancer
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DISCO: A Patient Intervention to Reduce the Financial Burden of Cancer
NCT04766190
Recruiting
The DISCO App is designed to improve, during the interaction, patient active participation and patient-initiated oncologist treatment cost discussions, and, in the short term, patient's treatment cost knowledge, self-efficacy for managing both cost and physician interactions, referrals, perceived financial toxicity (i.e., distress and material hardship); in turn, these will affect longer-term outcomes of financial toxicity and adherence.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/14/2024
Locations: Barbara Ann Karmanos Cancer Institute, Detroit, Michigan
Conditions: Financial Toxicity, Cancer, Question Prompt List, Breast Cancer, Prostate Cancer
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Cultural Tailoring and Pilot Testing of an Inpatient Yoga Therapy Program for Cancer Patients Undergoing Hematopoietic Stem Cell Transplantation in India, Tanzania, and the United States
NCT05681026
Recruiting
To develop and measure the effects of a culturally sensitive yoga program for inpatients
Gender:
All
Ages:
18 years and above
Trial Updated:
05/13/2024
Locations: M D Anderson Cancer Center, Houston, Texas
Conditions: Hematopoietic Stem Cell Transplantation, Cancer
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A Dyadic Intervention for Young Adult Patients With Cancer and Their Partner Caregivers
NCT06172907
Recruiting
The purpose of this pilot study is to examine the feasibility and acceptability of a brief psychotherapy intervention to improve psychosocial coping and maintain couple relationships among young adults (aged 25-39) with cancer and their caregiving partners.
Gender:
All
Ages:
Between 25 years and 39 years
Trial Updated:
05/13/2024
Locations: Massachusetts General Hospital Cancer Center, Boston, Massachusetts +3 locations
Conditions: Cancer, Survivorship, Caregiver Burden, Psychological Distress, Coping Skills, Couples
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Evaluating Personalized Therapeutics Clinic (PTC) on Drug-Drug Interactions and Drug-Gene Interactions
NCT05166694
Recruiting
The purpose of this study is to determine whether a consultation with a Personalized Therapeutics Clinic, or PTC, will help participants lower the risk for side effects (drug-drug interactions and drug-gene interactions) when taking many medications and help providers improve prescribing decisions for participants. A PTC is a clinical that will test your genes to gather information about your health that may help guide prescribing advice and offer you new information about your prescriptions. Do... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/10/2024
Locations: University of Chicago Medicine, Chicago, Illinois
Conditions: Cancer, Advanced Cancer, Advanced Solid Tumor, Mental Health Issue, Behavior Disorders
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Correlates of CRCI and Gut Microbiome Dysbiosis; a Pilot Study
NCT06098404
Recruiting
The aim of this study is to characterize the microbiome and assess fatigue and cognition of patients with cancer undergoing standard of care treatment.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/07/2024
Locations: The University of Texas Medical Branch, Galveston, Texas
Conditions: Cancer
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A Study of AdAPT-001 in Subjects With Sarcoma and Refractory Solid Tumors
NCT04673942
Recruiting
AdAPT-001 is an oncolytic virus that is injected directly into the tumor or via intraarterial administration. The purpose of this study is to find out if AdAPT-001 is safe and tolerable. The next step is to find out if AdAPT-001 if efficacious with or without a checkpoint inhibitor.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/07/2024
Locations: City of Hope, Duarte, California +5 locations
Conditions: Solid Tumor, Adult, Cancer, Neoplasms, Sarcoma, Sarcoma,Soft Tissue, Chondrosarcoma
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Short Term Genetic Effects of Chemotherapy on Male Germ Cells
NCT02975245
Recruiting
This study will determine the short-term effects of chemotherapy on sperm DNA.The study involves the collection of semen sample through ejaculation prior to initiation of chemotherapy and up to three time points after initiation of chemotherapy.
Gender:
Male
Ages:
Between 18 years and 50 years
Trial Updated:
05/07/2024
Locations: Magee-Womens Hospital, Pittsburgh, Pennsylvania
Conditions: Cancer
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Ovarian Tissue Cryopreservation for Fertility Preservation
NCT05875155
Recruiting
The goal of this observational study is to learn about fertility preservation for pre-pubertal, peri-pubertal, and adult participants that are unable to pursue clinical standard of care fertility preservation such as egg (oocyte) and embryo cryopreservation. In addition, this study will provide research tissue for the following Specific Aims: To optimize techniques for cryopreservation of ovarian tissues from patients at significant risk for infertility. To investigate factors affecting succes... Read More
Gender:
Female
Ages:
39 years and below
Trial Updated:
05/07/2024
Locations: Magee-Womens Hospital, Pittsburgh, Pennsylvania
Conditions: Cancer, Autoimmune Diseases
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A Study Assessing KB707 for the Treatment of Locally Advanced or Metastatic Solid Tumors
NCT05970497
Recruiting
KB707-01 is a Phase 1, open-label, multicenter, dose escalation and expansion study to evaluate the safety and tolerability of KB707 in adults with locally advanced or metastatic solid tumors who have progressed on standard of care therapy, cannot tolerate standard of care therapy, refused standard of care therapy, or for whom there is no standard of care therapy. In this study, patients will receive KB707 via direct intratumoral (IT) injection into solid tumors to assess the safety and tolerabi... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/07/2024
Locations: Stanford Cancer Center, Palo Alto, California +10 locations
Conditions: Cancer, Melanoma Stage III, Melanoma Stage IV, Cutaneous Melanoma, Osteosarcoma, Carcinoma, Squamous Cell, Carcinoma, Basal Cell
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Psycho-Spiritual Management for Patients With Advanced Cancer and Their Family Caregivers
NCT06409065
Recruiting
The goal of this behavioral research study is to learn about the effects of two different supportive care programs on patients' and their family caregivers' psychological wellbeing and overall quality of life.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/07/2024
Locations: MD Anderson, Houston, Texas
Conditions: Cancer
Register for Updates