There are currently 104 active clinical trials seeking participants for Asthma research studies. The states with the highest number of trials for Asthma participants are California, Texas, Florida and Ontario.
Lung Function Outcomes Following Removal of Airway Mucus Plugs in Patients With Asthma (FOCUS)
NCT05748912
Recruiting
This is a single-center study that will evaluate the safety and tolerability of removal of mucus plugs by bronchoscopy in patients with asthma. This protocol will also plan for the analysis of the features of the mucus plugs removed.
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
02/17/2023
Locations: UCSF Airway Clinical Research Center, San Francisco, California
Conditions: Asthma
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Blood Lymphocytes in Asthmatics Treated With Therapeutic Proteins
NCT04514926
Recruiting
This is an observational, clinic-based, single center study of 120 subjects. Participants will be comprised of patients seen in the outpatient faculty practice in ambulatory care at the UCSF Parnassus campus. Study investigators will enroll 20 healthy participants with no history of lung disease, 50 asthmatics who are newly prescribed therapeutic proteins for their asthma, and 50 asthmatics already being treated with therapeutic proteins for their asthma. Participants will be seen at 1 to 3 visi... Read More
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
02/09/2023
Locations: University of California, San Francisco, San Francisco, California
Conditions: Asthma, Therapeutic Proteins
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The Effect of NAC on Lung Function and CT Mucus Score
NCT03822637
Recruiting
This study evaluates 20% n-acetylcysteine (NAC) in the treatment of moderate-to-severe asthma that is complicated by mucus in the airway, as determined by CT imaging. The study is a crossover design, which means that half the study participants will get 20% NAC in the first 14-day treatment period and placebo in the next 14-day treatment period; and the other half will get placebo in the first 14-day treatment period and 20% NAC in the next 14-day treatment period.
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
02/08/2023
Locations: UCSF Airway Clinical Research Center, San Francisco, California
Conditions: Asthma
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Tissue Immune Interaction in Nasal Polyposis
NCT04628442
Recruiting
This is a cross-sectional study of up to 100 subjects who are undergoing clinically indicated sinus procedures to treat chronic rhinosinusitis. Participants will be asked to donate leftover sino-nasal secretions, sino-nasal tissue and blood as well as undergo partial characterization. As optional extensions of the main study, participants may also undergo a biopsy of extra sino-nasal tissue for additional tissue analysis and/or a more detailed characterization visit performed in the UCSF Airway... Read More
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
02/08/2023
Locations: UCSF Airway Clinical Research Center, San Francisco, California
Conditions: Chronic Rhinosinusitis (Diagnosis), Chronic Rhinosinusitis With Nasal Polyps, Asthma
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Obesity, Metabolic Dysregulation and the Airway Epithelium in Asthmatics
NCT03215836
Recruiting
The objective of this pilot study is to determine whether obesity and metabolic syndrome are in fact synergistic in relation to airway nitric oxide (NO) biology. To do so, the investigators want to determine how obesity and the metabolic syndrome relate to metabolism in bronchial airway epithelial cells and the nasal epithelium.
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
02/01/2023
Locations: University of Colorado, Aurora, Colorado
Conditions: Asthma, Obesity, Metabolic Syndrome
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Remote Monitoring of High-Risk Patients With Chronic Cardiopulmonary Diseases
NCT04825067
Recruiting
In this project, Institute of Bioengineering & Bioimaging (IBB), A*STAR would like to collaborate with Massachusetts General Hospital to aggregate patient data and to further develop its software algorithm using machine learning and statistical models for predicting exacerbations and deterioration on 60 patients with cardiopulmonary diseases.
Gender:
All
Ages:
18 years and above
Trial Updated:
09/27/2022
Locations: Integrated Care Management Program, Boston, Massachusetts
Conditions: Congestive Heart Failure, Asthma, Chronic Obstructive Pulmonary Disease, Cystic Fibrosis
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Home Air Quality Impact for Adults With Asthma
NCT05224076
Recruiting
The purposes of this study are to determine the practicality of using home indoor air quality monitoring and a smartphone app to identify home air quality changes and how these changes affect adults with asthma.
Gender:
All
Ages:
18 years and above
Trial Updated:
07/08/2022
Locations: Barbara J Polivka, Kansas City, Kansas
Conditions: Asthma, Environmental Exposure, Home Environment Related Disease
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Measuring Omalizumab Responses Using Real-world Evidence (MORRE) Study
NCT04724278
Recruiting
Develop new real-world evidence indicators of worsening and improving asthma. Scientists will measure (1) steps per day, (2) duration and intensity of exercise per day, (3) sleep duration and the number of awakenings per night using Fitbit activity trackers. Scientists will measure asthma symptoms using a once-monthly custom survey delivered to participant smartphones via Twilio. Scientists may measure rescue medication use and adherence to maintenance medications using digital inhaler devices.... Read More
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
06/21/2021
Locations: National Jewish Health, Denver, Colorado
Conditions: Asthma
Register for Updates