There are currently 298 active clinical trials seeking participants for Cancer research studies. The states with the highest number of trials for Cancer participants are California, Texas, New York and Florida.
Avera Cancer Sequencing and Analytics Protocol (ASAP)
NCT05142033
Recruiting
The purpose of this study is to understand the breadth of molecular characteristics present in participants cared for in a large integrated, community-based health care system. Using comprehensive genomic profiling and proteomics, the investigators seek to identify the underlying genomic drivers of premalignant or malignant conditions in participants across different stages of disease development and cancer types. Comprehensive molecular profiling will consist of somatic tumor testing (tissue a... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
02/23/2024
Locations: Avera Cancer Institute - Aberdeen, Aberdeen, South Dakota +1 locations
Conditions: Cancer, Cancer Diagnosis, Early Detection of Cancer, Breast Cancer, Lung Cancer, Colon Cancer, GI Cancer, Gynecologic Cancer, Ovarian Cancer, Endometrial Cancer, CNS Cancer, Hematologic Cancer
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Sirolimus in Combination With Metronomic Chemotherapy in Children With Recurrent and/or Refractory Solid and CNS Tumors
NCT02574728
Recruiting
This study aims to determine the efficacy of daily sirolimus and celecoxib, with low dose etoposide alternating with cyclophosphamide for pediatric participants with relapsed or refractory tumors.
Gender:
All
Ages:
Between 12 months and 30 years
Trial Updated:
02/21/2024
Locations: Phoenix Children's Hospital, Phoenix, Arizona +5 locations
Conditions: Cancer
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GOLD: Brief Intervention to Reduce Anxiety and Promote Resilience in Families of Youth With Cancer
NCT05415007
Recruiting
The purpose of this study is to examine a psychotherapeutic and psycho-educational intervention offered in virtual settings to caregivers of youth with cancer. Human subjects must be used because they are the object of the intervention.
Gender:
All
Ages:
Between 8 years and 18 years
Trial Updated:
02/21/2024
Locations: Stanford Cancer Institute, San Francisco, California
Conditions: Cancer
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DASH INtervention to INvestigate the Gut
NCT04538482
Recruiting
The study investigators will recruit a generally healthy sample of 112 black and white adults from Birmingham, AL to participate in a 28-day randomized, controlled feeding study. Participants will be randomized to receive either the DASH diet or a standard American diet. All meals will be provided by the study. Fecal samples will be collected at multiple time points before, during, and after the dietary intervention and will be analyzed using PCR to amplify the V4 region of the 16S rRNA gene and... Read More
Gender:
All
Ages:
Between 19 years and 65 years
Trial Updated:
02/19/2024
Locations: Moffitt Cancer Center, Tampa, Florida
Conditions: Microbiota, Cancer
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Construal Level as a Novel Pathway for Affect Regulation and Cancer Control
NCT04620915
Recruiting
The objective of the proposed research is to conduct a longitudinal experiment on the neurocognitive pathways and individual differences in high-level construal for affect regulation and smoking cessation. The population is adult smokers aged 25-55 who have tried and failed to quit and who are experiencing poverty. The primary endpoints are (a) the similarity in neural representation of high-level construal to one of two candidate pathways, (b) the presence of meaningful individual differences i... Read More
Gender:
All
Ages:
Between 25 years and 55 years
Trial Updated:
02/14/2024
Locations: University of Oregon, Lewis Integrative Sciences Building, Eugene, Oregon +1 locations
Conditions: Smoking Cessation, Smoking Reduction, Cancer
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My Wellbeing Guide: A Novel Tool for Managing Stress and Improving Quality of Life
NCT05369429
Recruiting
The purpose of this study is to examine the implementation and effectiveness of the psychosocial eHealth intervention, My Wellbeing Guide, on the proposed primary outcome, depressive symptoms, in patients diagnosed with cancer who receive care at Northwestern Medicine and the University of Miami Health System. The intervention includes cognitive behavioral therapy management strategies for health-related stress in the form of animated videos, interactive activities, and written content. The int... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
02/14/2024
Locations: Northwestern University, Chicago, Illinois
Conditions: Cancer, Anxiety, Depressive Symptoms
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Decreasing Polypharmacy in Older Adults With Curable Cancers Trial
NCT05046171
Recruiting
This is a single-site cluster-randomized trial to assess efficacy and implementation outcomes of deprescribing interventions in 72 older adults with polypharmacy (PP) and curable cancers initiating chemotherapy. Oncologists (as the cluster) will enroll 6 patients each and will be randomized to either a pharmacist-led deprescribing intervention or patient education intervention. Initial focus groups with oncologists, nurses, pharmacists, primary care physicians, and patients will provide data for... Read More
Gender:
All
Ages:
65 years and above
Trial Updated:
02/13/2024
Locations: University of Rochester, Rochester, New York
Conditions: Cancer
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Autoimmunity After Checkpoint Blockade
NCT04119713
Recruiting
The purpose of this study is to better understand how the treatment of cancer with immune checkpoint inhibitors (ICI) leads to the development of autoimmunity. Specifically, we wish to understand the genetics and immune system features that cause a subset of cancer patients treated with checkpoint inhibitor therapy to develop an immune-related adverse event (irAE).
Gender:
All
Ages:
18 years and above
Trial Updated:
02/13/2024
Locations: University of Pennsylvania - Abramson Cancer Center, Philadelphia, Pennsylvania
Conditions: Autoimmunity, Cancer, Immunotoxicity, Oncology
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Enhancing Cancer Survivorship With Pickleball
NCT06048822
Recruiting
The purpose of the study is to evaluate the feasibility and acceptability of a pickleball program for cancer survivors and their family members or friends. The program is designed to increase physical activity, improve wellness, and allow individuals to work together to learn and practice the sport.
Gender:
All
Ages:
18 years and above
Trial Updated:
02/12/2024
Locations: Moffitt Cancer Center, Tampa, Florida
Conditions: Cancer
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Evaluating Safety and Biomarkers Using DK210 (EGFR) for Locally Advanced or Metastatic EGFR+ Tumors
NCT05704985
Recruiting
This study will evaluate safety, pharmacodynamics and biomarkers of subcutaneous (SC) DK210(EGFR) given as monotherapy and in combination with immunotherapy, chemotherapy or radiation.
Gender:
All
Ages:
18 years and above
Trial Updated:
02/09/2024
Locations: City of Hope, Duarte, California +6 locations
Conditions: Cancer, Solid Tumor, Colorectal Cancer, Pancreas Cancer, Non Small Cell Lung Cancer, Head and Neck Cancer, Gynecologic Cancer, Skin Cancer, Kidney Cancer
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PTSD Mobile App for Cancer Survivors
NCT04058795
Recruiting
The purpose of this study is to use a stepped-care approach in treating symptoms of posttraumatic stress disorder (PTSD). The information learned by doing this study may help us to develop some target treatments for PTSD symptoms in survivors of stem cell transplant. Participants in this study will be randomized to a mobile app or usual care. An assessment will be made after 4 weeks and a determination made of adding more intensive treatment. Participants will be asked to complete a questionnai... Read More
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
02/09/2024
Locations: Memorial Sloan Kettering, New York, New York +2 locations
Conditions: Posttraumatic Stress Disorder, Cancer
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Genetic Testing in Young Adults With Cancer Study
NCT04533555
Recruiting
The overarching goal of our research is to define an evidence-based, sustainable approach to identifying and managing genetic risk among young adults with cancer and their relatives. Conventional practice leaves referral and testing decisions to mostly non-expert clinicians implementing complex guidelines at the point of care, leading to substantial under-utilization. The investigators hypothesize that panel-based universal screening coupled with electronic medical record- (EMR-) based algorithm... Read More
Gender:
All
Ages:
Between 18 years and 40 years
Trial Updated:
02/07/2024
Locations: University of Pennsylvania, Philadelphia, Pennsylvania
Conditions: Cancer
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