There are currently 277 active clinical trials seeking participants for Cancer research studies. The states with the highest number of trials for Cancer participants are California, Texas, New York and Florida.
Preoperative Immunotherapy in Patients with Squamous Cell Carcinoma of the Head and Neck
NCT03708224
Recruiting
To determine the effect of neoadjuvant atezolizumab alone or in combination with other immune modulating agents on T-cell infiltration in advanced SCCHN. To determine the impact of neo-adjuvant immunotherapy on surgical outcomes.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/24/2025
Locations: University of San Francisco, California, San Francisco, California
Conditions: Cancer, Carcinoma, Squamous Cell Carcinoma, Head and Neck Cancer
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Study of the CDK4/6 Inhibitor Abemaciclib in Solid Tumors Harboring Genetic Alterations in Genes Encoding D-type Cyclins or Amplification of CDK4 or CDK6
NCT03310879
Recruiting
This research study is studying a targeted therapy as a possible treatment for cancer abnormality in one of the following genes: CCND1, CCND2, CCND3, CDK4, or CDK6. The drug involved in this study is: -Abemaciclib
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/23/2025
Locations: Dana Farber Cancer Institute, Boston, Massachusetts
Conditions: Cancer
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Long-Term Follow-Up of Recipient of Gene Transfer Research
NCT01492036
Recruiting
The goal of this clinical research study is to collect information about the long-term safety of gene transfer therapy. This study is also designed to create a database of medical information about patients who have received gene transfer therapy, in order for researchers to track and review the long-term safety and any effects (good or bad) of gene transfer therapy.
Gender:
ALL
Ages:
All
Trial Updated:
01/22/2025
Locations: University of Texas MD Anderson Cancer Center, Houston, Texas
Conditions: Retroviridae Infections, Cancer
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Decision Support Training for Advanced Cancer Family Caregivers: the CASCADE Factorial Trial
NCT04803604
Recruiting
Using a highly innovative methodology, the Multiphase Optimization Strategy (MOST), the purpose of this randomized factorial trial is to identify components of a intervention (CASCADE) to enhance the decision support skills of family caregivers of persons with newly-diagnosed advanced cancer. Using a 2x2x2x2 full factorial design, 256 family caregivers of persons with newly-diagnosed advanced cancer will be randomized to receive one or more nurse coach-delivered decision partnering training comp... Read More
Gender:
ALL
Ages:
21 years and above
Trial Updated:
01/22/2025
Locations: University of Alabama at Birmingham, Birmingham, Alabama +1 locations
Conditions: Family Members, Cancer
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Fatigue and Molecular Mechanisms in Cancer Patients Receiving CCRT
NCT06633224
Recruiting
Cancer-related fatigue (CRF) is a significant problem for cancer patients. This prospective, basic science, observational study will evaluate for changes in CRF associated with molecular characteristics prior to, during, and at the completion of non-investigational, standard-of-care, combined chemotherapy and radiation therapy (CCRT) and to develop and assess predictive models for CRF severity.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/22/2025
Locations: University of California, San Francisco, San Francisco, California
Conditions: Cancer, Thoracic Cancer, Gynecologic Cancer, Head and Neck Cancer, Gastrointestinal Cancer
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Developing a Culturally Relevant Supportive Care Program for Black Patients Dealing with Advanced Cancer
NCT05763797
Recruiting
To determine the feasibility of implementing a culturally adapted mind-body intervention (Meditation-Based Support-Adapted; MBS-A) as a supportive care strategy in Black patients diagnosed with a stage III-IV solid malignancy. To target the specific needs of Black advanced cancer patients, we will first conduct formative research that includes quantitative surveys and in-depth interviews of patients and their primary caregivers. The purpose of this formative research is to determine the interven... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/22/2025
Locations: M D Anderson Cancer Center, Houston, Texas
Conditions: Cancer
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Study of RP1 Monotherapy and RP1 in Combination With Nivolumab
NCT03767348
Recruiting
RPL-001-16 is a Phase 1/2, open label, dose escalation and expansion clinical study of RP1 alone and in combination with nivolumab in adult subjects with advanced and/or refractory solid tumors, to determine the maximum tolerated dose (MTD) and recommended Phase 2 dose (RP2D), as well as to evaluate preliminary efficacy.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/22/2025
Locations: University of Birmingham Alabama, Birmingham, Alabama +52 locations
Conditions: Cancer, Melanoma (Skin), Mismatch Repair Deficiency, Microsatellite Instability, Non-melanoma Skin Cancer, Cutaneous Melanoma, NSCLC
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Clinical Validation of the Role of microRNA Binding Site Mutations in Cancer Risk, Prevention and Treatment
NCT02253251
Recruiting
The investigators will recruit and enroll individuals that may have the KRAS-variant or other microRNA binding site mutations to join registry studies. The investigators will allow individuals to obtain their results through a physician at the completion of the studies. The investigators current focus is cancer and autoimmunity.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/21/2025
Locations: MiraKind, Los Angeles, California
Conditions: Cancer
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Testicular Tissue Cryopreservation in Children
NCT02872532
Recruiting
This protocol is being designed to offer testicular tissue cryopreservation to male pediatric patients (0-17 years of age) with fertility threatening medical diagnoses or facing surgery, chemotherapy or radiation therapy that may cause loss of reproductive potential.
Gender:
MALE
Ages:
Between 0 years and 17 years
Trial Updated:
01/19/2025
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Cancer, Cancer-Related Condition, Infertility
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Optimal Perioperative Pain Control in Minimally Invasive Abdominal Cancer Surgery
NCT06731998
Recruiting
This is a research study to evaluate the effectiveness of 3 different types of routine pain management regimens used during clinically indicated, minimally invasive oncologic (cancer) surgery. This project is considered "Research" and participation is voluntary. Upon enrollment in this study, the research team will collect data from the patient's medical records. The patient will undergo all of the normal testing and procedures required pre-operatively (standard of care). The study team will the... Read More
Gender:
ALL
Ages:
Between 18 years and 89 years
Trial Updated:
01/15/2025
Locations: AHN West Penn Hospital, Pittsburgh, Pennsylvania
Conditions: Oncologic Surgery, Cancer, Cancer Surgery, Hepatic Cancer, Gastric (cardia, Body) Cancer, Biliary Tract Cancer, Pancreatic Cancer Resectable, Gynecologic Cancers, Gastrointestinal Cancers, Colorectal Cancer, Minimally Invasive Surgical Procedures
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IGNITE Firefighters' Health
NCT06567561
Recruiting
Investigators hope to learn about potential dietary intervention strategies (specifically a whole-food, plant-based diet) that may help lower cancer markers in firefighters.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/15/2025
Locations: Stanford University, Palo Alto, California
Conditions: Cancer, Inflammation, Microbiome, Immune Function
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My Wellbeing Guide: a Novel Tool for Managing Stress and Improving Quality of Life
NCT05369429
Recruiting
The purpose of this study is to examine the implementation and effectiveness of the psychosocial eHealth intervention, My Wellbeing Guide, on the proposed primary outcome, depressive symptoms, in patients diagnosed with cancer who receive care at Northwestern Medicine and the University of Miami Health System. Eligible patients will be directly contacted by the study team for recruitment. The intervention includes cognitive behavioral therapy management strategies for health-related stress in t... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/14/2025
Locations: Northwestern University, Chicago, Illinois
Conditions: Cancer, Anxiety, Depressive Symptoms
Register for Updates