There are currently 277 active clinical trials seeking participants for Cancer research studies. The states with the highest number of trials for Cancer participants are California, Texas, New York and Florida.
Development of Radiation Free Whole Body Magnetic Resonance (MR) Imaging Technique for Staging Children With Cancer
NCT01542879
Recruiting
A research study on the diagnosis of spread of disease for children who have been diagnosed with solid tumors using a new whole body imaging technique and a new MR contrast agent (ferumoxytol). Standard tests that are used to determine the extent and possible spread of a child's disease include magnetic resonance (MR) imaging, computed tomography (CT), Positron Emission Tomography (PET) as well as bone scanning, and metaiodobenzylguanidine (MIBG) scanning. The purpose of this study is to determi... Read More
Gender:
ALL
Ages:
Between 6 years and 40 years
Trial Updated:
11/20/2024
Locations: Stanford University Cancer Institute, Stanford, California
Conditions: Cancer
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Abatacept in Immune Checkpoint Inhibitor Myocarditis
NCT05335928
Recruiting
The primary aim is to test whether abatacept, as compared to placebo, is associated with a reduction in major adverse cardiac events (MACE) among participants hospitalized with myocarditis secondary to an immune checkpoint inhibitor (ICI). The primary outcome, MACE, is a composite of first occurrence of cardiovascular death, non-fatal sudden cardiac arrest, cardiogenic shock, significant ventricular arrythmias, significant bradyarrythmias, or incident heart failure.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/19/2024
Locations: Cedars-Sinai Medical Center, Los Angeles, California +30 locations
Conditions: Myocarditis Acute, Cancer
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Cryopreservation of Ovarian Tissue
NCT01558544
Recruiting
The study hopes to contribute to the development of technologies of ovarian tissue freezing-thawing and in vitro maturation of immature eggs such that a person at risk for premature ovarian failure might be able to conceive a genetically related child.
Gender:
FEMALE
Ages:
45 years and below
Trial Updated:
11/15/2024
Locations: Ronald O. Perelman and Claudia Cohen Center for Reproductive Medicine, New York, New York
Conditions: Cancer, Risk of Premature Ovarian Failure, Fertility Preservation
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Correlation Vitamin D Level to Endocrine Autoimmune Toxicity Due to Immune Checkpoint Inhibitors
NCT04615988
Recruiting
The purpose of this research study is to see if the amount of vitamin D in ones blood makes it more or less likely to develop thyroid gland toxicity when being treated with immunotherapy that blocks the activity of proteins called programed death-1(PD-1) or programmed death ligand-1 (PD-L1). Immunotherapy is treatment that makes changes to the immune system to try to fight cancer. Immunotherapy treatments that block the activity of important parts of the immune system called PD-1 and PD-L1 are u... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/14/2024
Locations: Mount Sinai Hospital /Tisch Cancer Cancer/Ruttenberg Treatment Center, New York, New York
Conditions: Thyroid, PD-1, Cancer
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Immune Profiling for Cancer Immunotherapy Response
NCT06116032
Recruiting
In patients clinically treated with FDA-approved immunotherapy the investigators will assess the predictive value of pre- and on-treatment 1) immune-methylation profiling across cancer types, and 2) immune-methylation profiling and cytokine profiling within cancer types.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/13/2024
Locations: Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire
Conditions: Cancer, Tumor, Solid, Hematologic Malignancy, Blood Cancer
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Phase 1a and Phase 2 Study for Safety, Preliminary Efficacy, PK and PD of ST-067
NCT04787042
Recruiting
This is a multiphase, multicenter study, which includes a Phase 1a open-label, dose escalation monotherapy study of ST-067 given as an SC injection with or without obinutuzumab \[Gazyva®\] pre-treatment, by IV infusion, and in combination with pembrolizumab. A Phase 2 monotherapy arm is also planned; the exact design of the Phase 2 study elements with respect to formulation and pre-treatment will be determined after completion of the Phase 1 study portion of the trial.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/13/2024
Locations: HonorHealth Research Institute, Scottsdale, Arizona +5 locations
Conditions: Cancer, Solid Tumor, Melanoma, Renal Cell Carcinoma, Triple-negative Breast Cancer, Non Small Cell Lung Cancer, Squamous Cell Carcinoma of the Head and Neck, Carcinoma, MSI-High
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Occupational Exposures Among Firefighters
NCT06173843
Recruiting
This study aims to understand the effect of occupational exposures, including PFAS exposures, among firefighters.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/12/2024
Locations: Vincere Cancer Center, Scottsdale, Arizona
Conditions: Cancer
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Decreasing Chemotherapy Induced Distress Using Immersive Virtual Reality in Patients With Cancer
NCT06446115
Recruiting
The goal of this clinical trial is to learn if the use of virtual reality during chemotherapy treatment helps participants achieve an improvement in distress, which may include unpleasant experience, anxiety, depression and/or pain. Participants will: * Be randomly assigned to one of two available groups (virtual reality or standard of care) * Participations will only be during one chemotherapy session. * Those assigned to virtual reality: * The research team will provide a virtual reality... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/11/2024
Locations: Cleveland Clinic Florida, Maroone Cancer Center, Weston, Florida
Conditions: Malignant Neoplasm, Cancer
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Selpercatinib Pre-RAI in Patients With RET Fusion Thyroid Cancer (RAISE)
NCT06458036
Recruiting
Papillary thyroid cancer (PTC) is the most common form of differentiated thyroid cancer (DTC). The traditional first line treatment for patients with advanced DTC after surgical resection is radioactive iodine (RAI) therapy. However, less than a quarter of patients with lung metastases will achieve a complete response to RAI therapy, and this therapy carries the risk of pulmonary fibrosis and an increasingly recognized risk of secondary malignancies.
Gender:
ALL
Ages:
Between 2 years and 21 years
Trial Updated:
11/11/2024
Locations: Children's Hospital of Philadelphia, Philadelphia, Pennsylvania
Conditions: Differentiated Thyroid Cancer, Pediatric Cancer, Cancer, Cancer, Thyroid
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A Dyadic Intervention for Young Adult Patients with Cancer and Their Partner Caregivers
NCT06172907
Recruiting
The purpose of this pilot study is to examine the feasibility and acceptability of a brief psychotherapy intervention to improve psychosocial coping and maintain couple relationships among young adults (aged 25-39) with cancer and their caregiving partners.
Gender:
ALL
Ages:
Between 25 years and 39 years
Trial Updated:
11/08/2024
Locations: Massachusetts General Hospital Cancer Center, Boston, Massachusetts +3 locations
Conditions: Cancer, Survivorship, Caregiver Burden, Psychological Distress, Coping Skills, Couples
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CAncer TReatment INformed by the Molecular Tumor Board At Dartmouth
NCT05405413
Recruiting
This is a single-arm Phase II study to measure the impact of Molecular Tumor Board treatment recommendations on treatment decision-making in clinical practice at the Dartmouth Cancer Center. Following tumor genetic profiling, subjects will be screened for eligibility. Eligible subjects' cases will be evaluated by the Dartmouth Cancer Center Molecular Tumor Board, and treatment recommendations will be entered into the medical record as per standard procedure. The primary endpoint is a survey res... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/06/2024
Locations: Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire
Conditions: Cancer
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Chinese American Cancer Survivors Writing Study
NCT05456100
Recruiting
The Chinese American Cancer Survivors Writing Study is a Randomized Controlled Trial (RCT) testing the feasibility and efficacy of the Expressive Helping (EH) intervention among Chinese American cancer survivors.
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
10/31/2024
Locations: New York University, New York, New York
Conditions: Cancer
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