There are currently 283 active clinical trials seeking participants for Cancer research studies. The states with the highest number of trials for Cancer participants are California, Texas, New York and Florida.
Study of RP1 Monotherapy and RP1 in Combination With Nivolumab
NCT03767348
Recruiting
RPL-001-16 is a Phase 1/2, open label, dose escalation and expansion clinical study of RP1 alone and in combination with nivolumab in adult subjects with advanced and/or refractory solid tumors, to determine the maximum tolerated dose (MTD) and recommended Phase 2 dose (RP2D), as well as to evaluate preliminary efficacy.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/22/2025
Locations: University of Birmingham Alabama, Birmingham, Alabama +52 locations
Conditions: Cancer, Melanoma (Skin), Mismatch Repair Deficiency, Microsatellite Instability, Non-melanoma Skin Cancer, Cutaneous Melanoma, NSCLC
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Decision Support Training for Advanced Cancer Family Caregivers: the CASCADE Factorial Trial
NCT04803604
Recruiting
Using a highly innovative methodology, the Multiphase Optimization Strategy (MOST), the purpose of this randomized factorial trial is to identify components of a intervention (CASCADE) to enhance the decision support skills of family caregivers of persons with newly-diagnosed advanced cancer. Using a 2x2x2x2 full factorial design, 256 family caregivers of persons with newly-diagnosed advanced cancer will be randomized to receive one or more nurse coach-delivered decision partnering training comp... Read More
Gender:
ALL
Ages:
21 years and above
Trial Updated:
01/22/2025
Locations: University of Alabama at Birmingham, Birmingham, Alabama +1 locations
Conditions: Family Members, Cancer
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Fatigue and Molecular Mechanisms in Cancer Patients Receiving CCRT
NCT06633224
Recruiting
Cancer-related fatigue (CRF) is a significant problem for cancer patients. This prospective, basic science, observational study will evaluate for changes in CRF associated with molecular characteristics prior to, during, and at the completion of non-investigational, standard-of-care, combined chemotherapy and radiation therapy (CCRT) and to develop and assess predictive models for CRF severity.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/22/2025
Locations: University of California, San Francisco, San Francisco, California
Conditions: Cancer, Thoracic Cancer, Gynecologic Cancer, Head and Neck Cancer, Gastrointestinal Cancer
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Clinical Validation of the Role of microRNA Binding Site Mutations in Cancer Risk, Prevention and Treatment
NCT02253251
Recruiting
The investigators will recruit and enroll individuals that may have the KRAS-variant or other microRNA binding site mutations to join registry studies. The investigators will allow individuals to obtain their results through a physician at the completion of the studies. The investigators current focus is cancer and autoimmunity.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/21/2025
Locations: MiraKind, Los Angeles, California
Conditions: Cancer
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Testicular Tissue Cryopreservation in Children
NCT02872532
Recruiting
This protocol is being designed to offer testicular tissue cryopreservation to male pediatric patients (0-17 years of age) with fertility threatening medical diagnoses or facing surgery, chemotherapy or radiation therapy that may cause loss of reproductive potential.
Gender:
MALE
Ages:
Between 0 years and 17 years
Trial Updated:
01/19/2025
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Cancer, Cancer-Related Condition, Infertility
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IGNITE Firefighters' Health
NCT06567561
Recruiting
Investigators hope to learn about potential dietary intervention strategies (specifically a whole-food, plant-based diet) that may help lower cancer markers in firefighters.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/15/2025
Locations: Stanford University, Palo Alto, California
Conditions: Cancer, Inflammation, Microbiome, Immune Function
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Optimal Perioperative Pain Control in Minimally Invasive Abdominal Cancer Surgery
NCT06731998
Recruiting
This is a research study to evaluate the effectiveness of 3 different types of routine pain management regimens used during clinically indicated, minimally invasive oncologic (cancer) surgery. This project is considered "Research" and participation is voluntary. Upon enrollment in this study, the research team will collect data from the patient's medical records. The patient will undergo all of the normal testing and procedures required pre-operatively (standard of care). The study team will the... Read More
Gender:
ALL
Ages:
Between 18 years and 89 years
Trial Updated:
01/15/2025
Locations: AHN West Penn Hospital, Pittsburgh, Pennsylvania
Conditions: Oncologic Surgery, Cancer, Cancer Surgery, Hepatic Cancer, Gastric (cardia, Body) Cancer, Biliary Tract Cancer, Pancreatic Cancer Resectable, Gynecologic Cancers, Gastrointestinal Cancers, Colorectal Cancer, Minimally Invasive Surgical Procedures
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My Wellbeing Guide: a Novel Tool for Managing Stress and Improving Quality of Life
NCT05369429
Recruiting
The purpose of this study is to examine the implementation and effectiveness of the psychosocial eHealth intervention, My Wellbeing Guide, on the proposed primary outcome, depressive symptoms, in patients diagnosed with cancer who receive care at Northwestern Medicine and the University of Miami Health System. Eligible patients will be directly contacted by the study team for recruitment. The intervention includes cognitive behavioral therapy management strategies for health-related stress in t... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/14/2025
Locations: Northwestern University, Chicago, Illinois
Conditions: Cancer, Anxiety, Depressive Symptoms
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Transdiagnostic Intervention to Reduce Internalized Health-Related Stigma
NCT05561595
Recruiting
Stigma due to health conditions increases disease burden and adversely impacts health. The internalization of health-related stigma is associated with impaired mental health and quality of life. The current project will test the effects of a novel, transdiagnostic, group counseling intervention, and peer support, to determine the optimal method for helping patients cope with health-related stigma, reducing its internalization, and enhancing patient quality of life.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/14/2025
Locations: University of Florida, Gainesville, Florida
Conditions: Obesity, Skin Disease, Cancer, HIV, Diabetes, Chronic Pain
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Lymphedema Sensor Technology Development Study
NCT06778837
Recruiting
The goal of this clinical trial in adult patients diagnosed with upper extremity lymphedema is to test the safety and effectiveness of small, wearable sensors that may be able to measure lymphedema. The main questions this study aims to answer are: * Do these sensors detect lymphedema? * If so, how accurate are these wearable sensors? Participants will complete one in-person measurement session and one phone call with study staff 14 days after the measurement session to check-in on the partici... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/14/2025
Locations: Northwestern University, Chicago, Illinois
Conditions: Lymphedema Arm, Lymphedema, Cancer
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Evaluation of a Telehealth Oncofertility Care Intervention in Adolescent and Young Adult Cancer Patients
NCT05443737
Recruiting
The purpose of this study is to evaluate the effectiveness of a multi-component intervention to improve young cancer survivors' engagement in goal-concordant oncofertility care, concurrently with observing and gathering information on how the intervention is implemented. The investigators hypothesize that implementation of the intervention will result in increased young cancer survivors' engagement in goal-concordant oncofertility care.
Gender:
ALL
Ages:
Between 0 months and 50 years
Trial Updated:
01/08/2025
Locations: City of Hope, Duarte, California +3 locations
Conditions: Cancer, Fertility Preservation
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Intervening on Women's Health for Rural Young Cancer Survivors
NCT06664034
Recruiting
The purpose of this pilot study is to evaluate the feasibility of a multi-component intervention to improve young female cancer survivors' engagement in goal-concordant reproductive health care. The investigators hypothesize that implementation of the intervention will result in increased young cancer survivors' engagement in goal-concordant reproductive health care.
Gender:
FEMALE
Ages:
Between 15 years and 50 years
Trial Updated:
01/08/2025
Locations: San Diego State University - Imperial Valley/ School of Nursing, Brawley, California +3 locations
Conditions: Cancer, Fertility Issues, Contraception
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