There are currently 282 active clinical trials seeking participants for Cancer research studies. The states with the highest number of trials for Cancer participants are California, Texas, New York and Florida.
Spermatogonial Stem Cell (SSC) Transplant and Testicular Tissue Grafting
NCT04452305
Recruiting
Spermatogonial stem cell transplantation through ultrasound guided rete testis injection and testicular tissue grafting will be performed for participants who have frozen testicular tissue prior to gonadotoxic therapy. The purpose of this study is to test the safety and feasibility of these transplant technologies and restore fertility for these participants.
Gender:
MALE
Ages:
All
Trial Updated:
01/31/2025
Locations: Magee-Womens Hospital, Pittsburgh, Pennsylvania
Conditions: Infertility, Male, Cancer, Autoimmune Disorder
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Pilot Study of Management of Facial Paralysis in the Oncologic Patient: Nerve Transfer Techniques to Improve Facial Function and Quality of Life
NCT06667427
Recruiting
The goal of this research study is to measure changes in patients' quality of life after surgeries that affect the facial nerve, including nerve transfer as treatment for facial paralysis.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/31/2025
Locations: The University of Texas M. D. Anderson Cancer Center, Houston, Texas
Conditions: Cancer, Head and Neck Cancer
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Prevent Cancer- Greenville
NCT04947098
Recruiting
Prevent Cancer-Greenville was created to provide individuals with the opportunity to have their risk of developing cancer studied. Some individuals may be at a higher risk due to their personal lifestyle, family history and/or exposures. If subjects are found to be at high risk for developing a disease, they will be sent to a healthcare provider for further care.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/30/2025
Locations: Prisma Health-Upstate, Greenville, South Carolina
Conditions: Cancer, High-Risk Cancer
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A Study Assessing KB707 for the Treatment of Locally Advanced or Metastatic Solid Tumors
NCT05970497
Recruiting
KB707-01 is a Phase 1/2, open-label, multicenter, dose escalation and expansion study. The study will evaluate the safety and tolerability of KB707 in adults with locally advanced or metastatic solid tumors who have progressed on standard of care therapy, cannot tolerate standard of care therapy, refused standard of care therapy, or for whom there is no standard of care therapy as well as the safety, tolerability, preliminary efficacy, and immunologic effect of KB707 administered in combination... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/30/2025
Locations: UCLA Health, Los Angeles, California +13 locations
Conditions: Cancer, Melanoma Stage III, Melanoma Stage IV, Cutaneous Melanoma
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Behavioral Activation-Led Activity Engagement for Cancer Empowerment
NCT06796608
Recruiting
The goal of this study is to learn if behavioral activation can improve daily quality of life for patients with advanced cancer. The main questions it aims to answer are: * Can behavioral activation be adapted to help patients living with advanced cancer optimize their daily quality of life? * Can behavioral activation be delivered primarily via smartphone? Participants will: * Complete a demographic questionnaire at the beginning of the study and quality-of-life and activity questionnaires a... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/30/2025
Locations: UPMC Hillman Cancer Center, Pittsburgh, Pennsylvania
Conditions: Advanced Cancer, Cancer
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The Care Tracker Study: Using Patient-Reported Data to Address Racial Disparity in Cancer Treatment
NCT06096623
Recruiting
This study assesses the feasibility and acceptability of a brief electronic patient-reported outcome (ePRO) tool that allows patients to self-identify impending delays. The risk of treatment delays according to tumor type and race will be measured by both ePRO and electronic health record (EHR) tools. Data from this study and the association of social determinants of health could be useful to flag patients at risk of delay and due timely intervention for modifiable treatment barriers. The predic... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/29/2025
Locations: University of North Carolina, Chapel Hill, North Carolina
Conditions: Cancer, Breast Cancer, Colorectal Cancer
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Use of a Screening Tool to Describe HIV-Related Cancer Burden and Patient Characteristics in the AMC
NCT05510908
Recruiting
This study is being done to understand how many people with HIV (PWH) present for cancer care across the AIDS Malignancy Consortium in the United States and if there are reasons that some PWH choose to participate, or not in cancer clinical trials. Optional quality of life surveys will be used to learn more about how HIV and cancer and HIV and cancer treatment affect people.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/27/2025
Locations: Moores UCSD Cancer Center, La Jolla, California +14 locations
Conditions: HIV-Associated Malignant Neoplasm, HIV Infections, Cancer, AIDS Related Lymphoma, AIDS-related Kaposi Sarcoma, AIDS-Related Malignancy, Anal Cancer, HPV-Related Malignancy
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A Study of Shengbai Oral Formula to Assess Safety and Alleviation of Adverse Effects in Cancer Patients Undergoing Chemotherapy
NCT06706752
Recruiting
The goal of this clinical trial is to assess whether Shengbai Oral Formula is a viable option for treatment of fatigue, pain, and neutropenia in patients undergoing their third cycle of chemotherapy.
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
01/27/2025
Locations: Sutter Health, Oakland, California
Conditions: Cancer
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Preoperative Immunotherapy in Patients with Squamous Cell Carcinoma of the Head and Neck
NCT03708224
Recruiting
To determine the effect of neoadjuvant atezolizumab alone or in combination with other immune modulating agents on T-cell infiltration in advanced SCCHN. To determine the impact of neo-adjuvant immunotherapy on surgical outcomes.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/24/2025
Locations: University of San Francisco, California, San Francisco, California
Conditions: Cancer, Carcinoma, Squamous Cell Carcinoma, Head and Neck Cancer
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Bladder and Bone Effects of Pelvic Radiation Therapy in Childhood Cancer Survivors
NCT05818462
Recruiting
The aim of this study is to measure and evaluate the effects of pelvic external beam radiation therapy (EBRT) on lower urinary tract (LUT) function and bone mineralization.
Gender:
ALL
Ages:
Between 2 years and 40 years
Trial Updated:
01/24/2025
Locations: Colorado Research Center, Aurora, Colorado
Conditions: Cancer, Childhood Cancer
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A Randomized Controlled Trial of Inhaled Tranexamic Acid for the Treatment of Pulmonary Hemorrhage in Cancer Patients
NCT05053867
Recruiting
This is a drug study that will examine if inhaled tranexamic acid can improve mortality in patients with cancer-related pulmonary hemorrhage and respiratory failure as compared to usual care.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/24/2025
Locations: M D Anderson Cancer Center, Houston, Texas
Conditions: Pulmonary Hemorrhage, Cancer
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Study of the CDK4/6 Inhibitor Abemaciclib in Solid Tumors Harboring Genetic Alterations in Genes Encoding D-type Cyclins or Amplification of CDK4 or CDK6
NCT03310879
Recruiting
This research study is studying a targeted therapy as a possible treatment for cancer abnormality in one of the following genes: CCND1, CCND2, CCND3, CDK4, or CDK6. The drug involved in this study is: -Abemaciclib
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/23/2025
Locations: Dana Farber Cancer Institute, Boston, Massachusetts
Conditions: Cancer
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