There are currently 279 active clinical trials seeking participants for Cancer research studies. The states with the highest number of trials for Cancer participants are California, Texas, New York and Florida.
A Study of Shengbai Oral Formula to Assess Safety and Alleviation of Adverse Effects in Cancer Patients Undergoing Chemotherapy
NCT06706752
Recruiting
The goal of this clinical trial is to assess whether Shengbai Oral Formula is a viable option for treatment of fatigue, pain, and neutropenia in patients undergoing their third cycle of chemotherapy.
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
05/13/2025
Locations: Sutter Health, Oakland, California
Conditions: Cancer
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A New Psychotherapy Intervention for Older Cancer Patients
NCT04452825
Recruiting
This study is being done to see if a new psychotherapy intervention called Cancer and Aging: Reflections for Elders (CARE) can effectively treat depression and distress in older cancer patients. CARE is a 5-session intervention that takes place over the phone. This study will compare CARE with the Social Work and Supportive Counseling (SWSC) intervention, which also takes place over the phone. SWSC is a standard psychotherapeutic intervention that has been shown to be a supportive and effective... Read More
Gender:
ALL
Ages:
70 years and above
Trial Updated:
05/13/2025
Locations: Memorial Sloan Kettering Cancer Center, New York, New York
Conditions: Cancer
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Investigation of Profile-related Evidence Determining Individualized Cancer Therapy for Patients With Aggressive Malignancies and Poor Prognoses
NCT05674825
Recruiting
This is a prospective, open-label navigational investigation designed to evaluate the feasibility of using molecular profile-based evidence to determine individualized cancer therapy for patients with aggressive malignancies. This is a non-randomized, histology-agnostic trial. Although there will be a case mix of histologies, the investigators now know that individual histologies are composed of a heterogeneous mix of molecular alterations. It is not clear whether one case mix is better or worse... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/12/2025
Locations: Froedtert Hospital & the Medical College of Wisconsin, Milwaukee, Wisconsin
Conditions: Cancer
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Decreasing Polypharmacy in Older Adults With Curable Cancers Trial
NCT05046171
Recruiting
This is a single-site cluster-randomized trial to assess efficacy and implementation outcomes of deprescribing interventions in 72 older adults with polypharmacy (PP) and curable cancers initiating chemotherapy. Oncologists (as the cluster) will enroll 6 patients each and will be randomized to either a pharmacist-led deprescribing intervention or patient education intervention. Initial focus groups with oncologists, nurses, pharmacists, primary care physicians, and patients will provide data for... Read More
Gender:
ALL
Ages:
65 years and above
Trial Updated:
05/12/2025
Locations: University of Rochester, Rochester, New York
Conditions: Cancer
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Isa-Rd for Frail and/or Much Older Patients With Newly Diagnosed Multiple Myeloma
NCT05145400
Recruiting
This research study is investigating the safety and effectiveness of using combination of isatuximab, lenalidomide and dexamethasone for the treatment of newly diagnosed multiple myeloma (MM). The study team will use lower doses than is currently standard for these drugs. Lower doses will be used to avoid or possibly reduce any unwanted side effects commonly associated with these drugs. Using lower doses of the combination isatuximab, lenalidomide and dexamethasone, has not been approved by the... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/09/2025
Locations: University of North Carolina at Chapel Hill, Lineberger Comprehensive Cancer Center, Chapel Hill, North Carolina +4 locations
Conditions: Multiple Myeloma, Cancer
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Dietary Interventions in Cancer Patients Treated With Immune Checkpoint Inhibitors
NCT06475807
Recruiting
This pilot trial will study the potential impact of two distinct dietary interventions with sequential use of high-fermented foods and high-fiber supplements on the gut microbiome and antitumor immunity in patients with melanoma and non-small cell lung cancer (NSCLC) treated with immune checkpoint inhibitors. The trial aims to understand how dietary changes affect the composition and function of the gut microbiome, together with immunological and metabolomic markers in serum in patients with mel... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/08/2025
Locations: UPMC Hillman Cancer Center, Pittsburgh, Pennsylvania
Conditions: Cancer
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Study of INKmune in Patients With mCRPC (CaRe Prostate)
NCT06056791
Recruiting
This is an open-label, phase I/IIa dose escalation and expansion study of INKmune in men with mCRPC. INKmune is administered to patients intravenously over three doses, at least one-week apart. The study will consist of two stages.
Gender:
MALE
Ages:
18 years and above
Trial Updated:
05/08/2025
Locations: VA Greater Los Angeles Healthcare System, Los Angeles, California +7 locations
Conditions: Cancer, Metastatic Castration-resistant Prostate Cancer, mCRPC
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UNC Childhood, Adolescent, and Young Adult Cancer Cohort
NCT05096923
Recruiting
Purpose: This study aims to create a registry of childhood, adolescent, and young adult patients with cancer (\<40 years-old at cancer diagnosis), entitled the 'UNC Childhood, Adolescent, and Young Adult Cancer Cohort' (UNC-CAYACC). This resource will serve to support cancer outcomes research among pediatric and young adult cancer patients with a primary focus on enrolling patients treated as adolescents or young adults (AYAs, 15-39 years). Procedures: As appropriate for age, participants will... Read More
Gender:
ALL
Ages:
Between 1 year and 39 years
Trial Updated:
05/07/2025
Locations: University of North Carolina at Chapel Hill, Chapel Hill, North Carolina
Conditions: Pediatric Cancer, Cancer, Cancer Metastatic, Survivorship
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Patient-Reported Outcome Version of the Common Criteria for Adverse Events
NCT04050072
Recruiting
Childhood cancer survivors are vulnerable to treatment-related late effects, including physical and psychosocial morbidities, subsequent malignancies, and premature death. Symptom assessment provides a unique insight into survivorship care since symptoms not only indicate the manifestation for the occurrence of chronic health conditions, but also impact quality of life and survival. The National Cancer Institute (NCI) has developed a Patient-Reported Outcomes version of the Common Terminology Cr... Read More
Gender:
ALL
Ages:
16 years and above
Trial Updated:
05/06/2025
Locations: St. Jude Children's Research Hospital, Memphis, Tennessee
Conditions: Survivorship, Cancer
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TEMPUS ARIES: A Biobank Registry Platform Study in Oncology
NCT06207032
Recruiting
This study is a non-interventional, multicenter, multicohort evaluation of participants with cancer who will undergo longitudinal plasma ctDNA biomarker profiling at specific time points in addition to standard of care therapy.
Gender:
ALL
Ages:
Between 18 years and 99 years
Trial Updated:
05/05/2025
Locations: Alabama Oncology, Birmingham, Alabama +27 locations
Conditions: Cancer
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Improving Cancer Prevention and Control Through Academic-local Public Health Department Partnerships
NCT06605196
Recruiting
The purpose of this study is to understand how to leverage structures and processes of academic health department (AHD) partnerships to facilitate implementation of cancer related evidence-based programs and policies (EBPPs).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/02/2025
Locations: Prevention Research Center at Washington University in St. Louis, Saint Louis, Missouri
Conditions: Cancer
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Implement and Test Visual Consent Template and Process
NCT06804837
Recruiting
The investigators plan to conduct a stepped wedge randomized control trial to implement and test the consent template and process in three studies. Randomization will occur at the research coordinator/research team level. Each participating research team member will begin in the standard consent arm of the study. Subsequently, they will be randomized to the visual key information page arm at staggered time points to undergo training and begin using the visual key information page with patients w... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/02/2025
Locations: Washington University School of Medicine, Saint Louis, Missouri +2 locations
Conditions: Cancer, Alzheimer Disease
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