There are currently 118 active clinical trials seeking participants for Dementia research studies. The states with the highest number of trials for Dementia participants are Florida, California, New York and Ontario.
Effects of THC-Free CBD Oil on Agitation in Patients With Alzheimer's Disease
NCT04436081
Recruiting
This is a randomized, double-blinded, placebo-controlled, crossover trial that aims to 1) determine the efficacy of THC-free cannabidiol (CBD oil) in reducing the severity of agitation among participants and 2) determine whether THC-free CBD oil can reduce the burden on caregivers and increase the participants' quality of life.
Gender:
All
Ages:
Between 50 years and 90 years
Trial Updated:
02/15/2023
Locations: Eastern Virginia Medical School, Norfolk, Virginia
Conditions: Alzheimer Disease, Dementia, Major Neurocognitive Disorder With Aggressive Behavior
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The Influence of the Otago Exercise Program on Executive Function Among People Living With Mild to Moderate Dementia
NCT05488951
Recruiting
The primary aim of this study is to conduct a pilot 6-month assessor-blinded randomized controlled trial to determine if the Otago Exercise Program plus usual care improves executive function in people living with mild to moderate dementia compared to usual care among those living in a nursing home or assisted living facility. The exploratory aims are to determine if the Otago Exercise Program plus usual care improves inflammatory blood biomarkers, kynurenine metabolites, epigenetics, mobility,... Read More
Gender:
All
Ages:
55 years and above
Trial Updated:
01/30/2023
Locations: Augusta University, Augusta, Georgia
Conditions: Dementia
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Comparison of Two Group Wellness Interventions for Individuals With Neurologic Conditions and Their Support Persons
NCT05048966
Recruiting
Approximately 5.3 million people live with a long-term disability resulting from a traumatic brain injury (TBI) and between 5-8% of those older than 60 suffer from Alzheimer's disease or other forms of dementia (ADRD). Consequences of these conditions can result in dramatic and persistent changes in functioning, impacting not only the patients, but also loved ones who become informal support persons. Many existing services help the family in the moment, but do not address long-term wellness. Thu... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
12/14/2022
Locations: Kessler Foundation, East Hanover, New Jersey
Conditions: Traumatic Brain Injury, Mild Traumatic Brain Injury, Alzheimer's Disease, Brain Injury Traumatic Moderate, Brain Injury Traumatic Severe, Dementia
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Phase I Human Analytics (HALO) Study
NCT05423860
Recruiting
Discover, optimize, standardize, and validate clinical-trial measures and biomarkers used to diagnose and differentiate cardiovascular, oncologic, neurologic, and other diseases and disorders. Specifically, our research study endeavors to improve disease and disorder diagnosis to the earliest clinical states, in preclinical states, and to develop ensemble multivariate biomarker risk scores leading to cardiovascular, oncologic, neurologic, and other diseases and disorders. Additionally, the stud... Read More
Gender:
Male
Ages:
Between 45 years and 90 years
Trial Updated:
10/12/2022
Locations: Desert Medical Imaging, Indian Wells, California
Conditions: Cardiovascular Diseases, Cancer, Dementia, Traumatic Brain Injury
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The A-LIST WMM Insights Series
NCT04466722
Recruiting
The main purpose of the Study is to develop an understanding over time and through multiple research projects, including surveys, interviews, online focus groups, and other primary research methodologies (A-LIST Research Projects) on what matters most to individuals concerned about brain health and those with and/or affected by Alzheimer's disease and other dementias, including caregivers.
Gender:
All
Ages:
Between 18 years and 100 years
Trial Updated:
06/13/2022
Locations: UsAgainstAlzheimer's, Washington, District of Columbia
Conditions: Alzheimer Disease, Dementia, Mild Cognitive Impairment
Register for Updates
Creating Physical Objects With 3D Printers to Stimulate Reminiscing for Memory Loss [2 R44 AG049548-02A1]
NCT03625973
Recruiting
In 2013 an estimated 5 million people age 65 and older had Alzheimer's disease. Longer life spans and aging baby boomers will cause this number to grow rapidly. More than 50% of residents in assisted living and nursing homes have some form of dementia or cognitive impairment and the number is increasing every day. As a form of person-centered, non-pharmacological dementia care, Reminiscence Therapy (RT) holds considerable promise. Improvements in mood, quality of life, social interaction, cogni... Read More
Gender:
All
Ages:
All
Trial Updated:
04/18/2022
Locations: Saint Louis University, Saint Louis, Missouri +1 locations
Conditions: Dementia
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LEAD IT! An App to Enable Persons With Early Stage Dementia to Lead Group Activities for Their Peers
NCT04899973
Recruiting
The proposed Phase 2 project will involve the further development and evaluation of LEAD IT!, which is a tablet-based app designed to enable persons with dementia to lead activities for their peers (i.e., other persons with dementia). The study will examine the clinical outcomes of long-term use of the app by both Resident Leaders (RLs) and Resident Players (RPs). The Specific Aims of the proposed Phase 2 project are to: Develop improved Beta 1 and Beta 2 Versions of LEAD IT! with sufficient c... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
11/30/2021
Locations: Hearthstone Alzheimer Care, Winchester, Massachusetts
Conditions: Dementia, Alzheimer Disease
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The Interactive Physical and Cognitive Exercise System (v3) for Mild Cognitive Impairment (MCI)
NCT05009524
Recruiting
The primary purpose of this study is to attempt to replicate and extend promising pilot findings regarding the cognitive benefits of in-home neuro-exergaming with iPACES (interactive Physical and Cognitive Exercise System v3) for persons with mild cognitive impairment (MCI). Participants will include persons with MCI and their co-residing partner who both exercise at home 3-5 times per week for at least 6 months and are followed through one year. All participation is "remote" (completed at home)... Read More
Gender:
All
Ages:
50 years and above
Trial Updated:
11/18/2021
Locations: remote trial conducted via video-conference/mail in-home all locations in the continental USA, Clifton Park, New York
Conditions: MCI, Mild Cognitive Impairment, Alzheimer Disease, Dementia
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On Site Sensors Monitoring Impacts of Cognitive Decline on ADLs
NCT04871698
Recruiting
The purpose of this research is to compare the effectiveness of a continuous monitoring system to assess Activities of Daily Living (ADLs) over time compared to the traditional assessments used by medical professionals as Alzheimer's Disease and Alzheimer's Disease Related Dementias (AD/ADRD) progresses.
Gender:
All
Ages:
65 years and above
Trial Updated:
04/29/2021
Locations: Birkeland Current, Waco, Texas
Conditions: Dementia, Dementia Alzheimers
Register for Updates
DC Longitudinal Study on Aging and Specimen Bank
NCT03702907
Recruiting
The Georgetown University Memory Disorders Program, part of the Department of Neurology, is conducting pilot studies of the feasibility of various diagnostic tests for Alzheimer's disease, mild cognitive impairment and other neurodegenerative diseases. Further, this study is assessing longitudinal changes in biological, lifestyle, and cognitive assessment collection. The primary goal of this study is to examine the feasibility of biochemical assays, genetic testing, and cognitive and lifestyle... Read More
Gender:
All
Ages:
45 years and above
Trial Updated:
10/23/2019
Locations: Georgetown University Memory Disorders Program, Washington, District of Columbia
Conditions: Alzheimer Disease, Dementia, Mild Cognitive Impairment, Aging, Aging Disorder
Register for Updates