There are currently 128 active clinical trials seeking participants for Dementia research studies. The states with the highest number of trials for Autism participants are Florida, California, New York and Pennsylvania.
EPIC: An Intervention for Early-stage AD Dyads - Adapted for Virtual Delivery
NCT03144921
Recruiting
EPIC II (Early-Stage Partners in Care) is a research project designed to assist people with early-stage memory loss and their care partners by providing early-stage related education and skill-training sessions, held via Zoom, designed to reduce stress, enhance well-being, manage challenges, and plan for the future. Researchers will gather feedback from individuals about their experience to continue to improve programs for early-stage memory loss.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/01/2023
Locations: Nationwide Program Locations (Based at ASU Edson College of Nursing and Health Innovation), Phoenix, Arizona
Conditions: Dementia, Alzheimer Disease, Memory Loss
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Pilot Mobile for Dementia and Frailty
NCT05827094
Recruiting
In this project, we propose to build on our Stage I formative work (according to the NIH Stage Model for Behavioral Intervention Development), where we developed fully functional prototypes of a mobile intervention aimed at improving adherence to Mediterranean Diet (MedD) for older adults with frailty and early dementia to complete the Stage II exploratory work, where the intervention will undergo further feasibility, acceptability, and preliminary efficacy tests. The intervention includes a pat... Read More
Gender:
All
Ages:
65 years and above
Trial Updated:
04/12/2023
Locations: Univeristy of Washington, Seattle, Washington
Conditions: Dementia, Frailty
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Non-invasive Brain Stimulation for Cognitive and Motor Dysfunction in Dementia
NCT05661084
Recruiting
This project aims to examine the efficacy of remote, caregiver-led tES/brain stimulation intervention targeted to improve memory, mobility, and executive functioning among older adults with mild cognitive impairment or mild dementia.
Gender:
All
Ages:
55 years and above
Trial Updated:
04/02/2023
Locations: Hinda and Arthur Marcus Institute for Aging Research, Boston, Massachusetts
Conditions: Dementia, Memory Loss, Alzheimer Disease, Executive Dysfunction, Mobility Limitation
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Reducing Risk of Dementia Through Deprescribing
NCT04270474
Recruiting
A cluster-randomized controlled trial (RCT) called "Reducing Risk of Dementia through Deprescribing" (R2D2) to evaluate the impact of a deprescribing intervention on important cognitive and safety outcomes.
Gender:
All
Ages:
65 years and above
Trial Updated:
03/22/2023
Locations: Eskenazi Health, Indianapolis, Indiana +2 locations
Conditions: Dementia, Alzheimer Disease, Late Onset
Register for Updates
Changing Talk Online Training (CHATO) National Trial
NCT04610944
Recruiting
The National Plan to Address Alzheimer's disease has identified education of dementia care providers as a top priority to address the need for quality care for the population of persons with dementia that will triple in the next 30 years. This study will test new online interactive training for nursing home staff that improves staff communication and also reduces behavioral symptoms of persons with dementia that they care for. Innovative approaches to reach care providers are essential to achiev... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
03/14/2023
Locations: University of Kansas School of Nursing, Kansas City, Kansas
Conditions: Dementia, Alzheimer Disease, Communication
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Effects of THC-Free CBD Oil on Agitation in Patients With Alzheimer's Disease
NCT04436081
Recruiting
This is a randomized, double-blinded, placebo-controlled, crossover trial that aims to 1) determine the efficacy of THC-free cannabidiol (CBD oil) in reducing the severity of agitation among participants and 2) determine whether THC-free CBD oil can reduce the burden on caregivers and increase the participants' quality of life.
Gender:
All
Ages:
Between 50 years and 90 years
Trial Updated:
02/15/2023
Locations: Eastern Virginia Medical School, Norfolk, Virginia
Conditions: Alzheimer Disease, Dementia, Major Neurocognitive Disorder With Aggressive Behavior
Register for Updates
Alzheimer's Disease Treatment With Combination of 40Hz Light and Cognitive Therapy
NCT03657745
Recruiting
Electrical activity in the brain known as "gamma" brainwaves help connect and process information throughout the brain. These gamma waves are diminished in Alzheimer's disease. New research in Alzheimer's disease mouse models shows that exposure to light flickering at the rate of 40 flashes per second or 40Hz increased gamma brainwaves and led to clearing of beta amyloid plaques in the brain, a key abnormality in Alzheimer's disease. This project will test the ability of a novel iPad App (AlzLif... Read More
Gender:
All
Ages:
50 years and above
Trial Updated:
01/31/2023
Locations: Andrey Vyshedskiy, Miami, Florida
Conditions: Alzheimer Disease, Mild Cognitive Impairment, Dementia, Cognition Disorders in Old Age, Cognitive Decline, Cognitive Deterioration
Register for Updates
The Influence of the Otago Exercise Program on Executive Function Among People Living With Mild to Moderate Dementia
NCT05488951
Recruiting
The primary aim of this study is to conduct a pilot 6-month assessor-blinded randomized controlled trial to determine if the Otago Exercise Program plus usual care improves executive function in people living with mild to moderate dementia compared to usual care among those living in a nursing home or assisted living facility. The exploratory aims are to determine if the Otago Exercise Program plus usual care improves inflammatory blood biomarkers, kynurenine metabolites, epigenetics, mobility,... Read More
Gender:
All
Ages:
55 years and above
Trial Updated:
01/30/2023
Locations: Augusta University, Augusta, Georgia
Conditions: Dementia
Register for Updates
Comparison of Two Group Wellness Interventions for Individuals With Neurologic Conditions and Their Support Persons
NCT05048966
Recruiting
Approximately 5.3 million people live with a long-term disability resulting from a traumatic brain injury (TBI) and between 5-8% of those older than 60 suffer from Alzheimer's disease or other forms of dementia (ADRD). Consequences of these conditions can result in dramatic and persistent changes in functioning, impacting not only the patients, but also loved ones who become informal support persons. Many existing services help the family in the moment, but do not address long-term wellness. Thu... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
12/14/2022
Locations: Kessler Foundation, East Hanover, New Jersey
Conditions: Traumatic Brain Injury, Mild Traumatic Brain Injury, Alzheimer's Disease, Brain Injury Traumatic Moderate, Brain Injury Traumatic Severe, Dementia
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Apolipoprotein E (APOE) Genotype Effects on Triglycerides and Blood Flow in the Human Brain
NCT04692441
Recruiting
High fat feeding (HFF) increases the risk of Alzheimer's disease (AD) but individuals who carry the AD risk gene E4 paradoxically improve after acute HFF. The investigators propose to further study this phenomenon with a clinical study to assess cerebral blood flow which can be measured by a technique called arterial spin labeling (ASL) on an MRI and is tightly related to brain metabolism.
Gender:
All
Ages:
55 years and above
Trial Updated:
11/10/2022
Locations: University of Washington Medical Center, Seattle, Washington
Conditions: Alzheimer Disease, Dementia
Register for Updates
Phase I Human Analytics (HALO) Study
NCT05423860
Recruiting
Discover, optimize, standardize, and validate clinical-trial measures and biomarkers used to diagnose and differentiate cardiovascular, oncologic, neurologic, and other diseases and disorders. Specifically, our research study endeavors to improve disease and disorder diagnosis to the earliest clinical states, in preclinical states, and to develop ensemble multivariate biomarker risk scores leading to cardiovascular, oncologic, neurologic, and other diseases and disorders. Additionally, the stud... Read More
Gender:
Male
Ages:
Between 45 years and 90 years
Trial Updated:
10/12/2022
Locations: Desert Medical Imaging, Indian Wells, California
Conditions: Cardiovascular Diseases, Cancer, Dementia, Traumatic Brain Injury
Register for Updates
GamePlan4Care: Online Support for Family Caregivers
NCT04540198
Recruiting
As the population of older adults grows, almost doubling in size from 2012 to 2040, so too will the need for family caregiving. Caregiving can lead to negative psychosocial outcomes such as depression, anxiety, and burden; social isolation and family conflict: financial strain due to costs of care; and some caregivers also experience negative health consequences. This project will test the value of GamePlan4Care (GP4C) an evidence-based, internet-enabled system capable of providing immediate, ta... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
08/15/2022
Locations: Alzheimer's Texas, Austin, Texas
Conditions: Dementia
Register for Updates