There are currently 126 active clinical trials seeking participants for Dementia research studies. The states with the highest number of trials for Dementia participants are Florida, California, New York and Pennsylvania.
Stories in the Moment: Dance Program for People Living With Dementia
NCT06221202
Recruiting
This study is designed to evaluate the impact on the quality of life and wellbeing of a person-centered online dance program on people living with dementia or MCI and care partners. The duration of the study will be 1 year. Each participant in the study will be followed for approximately 4 months. The study includes joining a weekly 1-hour dance program online on Zoom for 12 weeks. Prior and after the dance program, participants will meet with the research coordinator to answer some questionnai... Read More
Gender:
All
Ages:
50 years and above
Trial Updated:
01/14/2024
Locations: Online, New York, New York
Conditions: Dementia, Mild Cognitive Impairment, Alzheimer Disease, Lewy Body Disease, Frontotemporal Dementia, Vascular Dementia
Register for Updates
Remote Game-based Exercise Program for Cognitive and Motor Function Improvement
NCT05235113
Recruiting
As our population ages, more older adults face motor-cognitive declines, increasing their risk of falls and fear of falling. Exercise is an effective way to maintain cognitive function, as supported by recent studies. However, those with poor motor and cognitive abilities often struggle to visit rehabilitation centers, leading to high dropout rates and low adherence to unsupervised programs. A remote exercise program tailored for individuals with cognitive impairments is urgently needed to prese... Read More
Gender:
All
Ages:
50 years and above
Trial Updated:
01/10/2024
Locations: Baylor College of Medicine, Houston, Texas
Conditions: Mild Cognitive Impairment, Dementia, Cognitive Impairment, Memory Loss
Register for Updates
A Technology-Driven Intervention to Improve Early Detection and Management of Cognitive Impairment
NCT05723523
Recruiting
Most experts advocate for early detection of cognitive impairment (CI) so that patients and caregivers can be prepared for making difficult decisions and to improve quality of life, but studies show that screening alone isn't sufficient to change clinician actions related to early detection. Using predictive modelling developed with machine learning methods and sophisticated clinical decision support (CDS) tools, it is possible to identify patients at elevated risk for CI and make it much easier... Read More
Gender:
All
Ages:
65 years and above
Trial Updated:
01/05/2024
Locations: HealthPartners, Bloomington, Minnesota +1 locations
Conditions: Dementia, Cognitive Impairment
Register for Updates
Financial Incentives and Recruitment to the APT Webstudy
NCT06033066
Recruiting
This single-blind, three-arm, randomized, controlled trial will assess the impact of messages and financial incentives on the enrollment of demographically diverse individuals to the Alzheimer Prevention Trials (APT) Webstudy. The APT Webstudy is a novel, online registry that employs quarterly cognitive testing using validated platforms. The APT Webstudy implements fully remote assessments, coordinated by the Alzheimer's Therapeutic Research Institute (ATRI) under USC IRB #HS-17-00746. The purpo... Read More
Gender:
All
Ages:
50 years and above
Trial Updated:
12/19/2023
Locations: Contra Costa Health Plan, Martinez, California
Conditions: Alzheimer Disease, Dementia, Preclinical Alzheimer's Disease, Prodromal Alzheimer's Disease
Register for Updates
Quality Improvement and Clinical Utility PrecivityAD2(TM) Clinician Survey
NCT06025877
Recruiting
There is a major unmet need for timely, non-invasive, and low-burden evaluation of patients presenting with mild cognitive impairment (MCI) and dementia. MCI impacts 12-18% of people in the United States over age 60 years (Alzheimer's Association. Mild Cognitive Impairment (MCI) available at https://www.alz.org/alzheimers-dementia/what-is-dementia/related_conditions/mild-cognitive-impairment. Accessed August 16, 2022). MCI does not substantially interfere with daily activities, although complex... Read More
Gender:
All
Ages:
55 years and above
Trial Updated:
12/13/2023
Locations: UCSF Memory and Aging Center, San Francisco, California +6 locations
Conditions: Alzheimer Disease, Mild Cognitive Impairment, Dementia, Cognitive Decline, Cognitive Impairment, Memory Impairment
Register for Updates
Treatment of Stress and Anxiety in MCI/Mild ADRD
NCT05748613
Recruiting
The goal of this clinical trial is to test the effectiveness of a computerized anxiety sensitivity treatment (CAST) compared to a health education control (HEC) in older adults with mild cognitive impairment (MCI) or mild Alzheimer's Disease and related dementias (ADRD) and their care partners. The main questions it aims to answer are: Efficacy of CAST in reducing anxiety and related symptoms among those with MCI/mild ADRD Efficacy of CAST in reducing care partner burden among care partners of... Read More
Gender:
All
Ages:
60 years and above
Trial Updated:
12/13/2023
Locations: Anxiety and Behavioral Health Clinic, Tallahassee, Florida +2 locations
Conditions: Anxiety, Mild Cognitive Impairment, Alzheimer Disease, Dementia
Register for Updates
Genetic Studies in Familial Dementia
NCT04680013
Recruiting
The purpose of this study is to identify genetic factors that contribute to or cause dementia (loss of memory) and related disorders across all ages and ethnic groups. This includes a number of neurological diseases such as early and late-onset Alzheimer disease, mild cognitive impairment, and other dementias.
Gender:
All
Ages:
18 years and above
Trial Updated:
12/02/2023
Locations: University of Miami, Miami, Florida
Conditions: Dementia of Alzheimer Type, Alzheimer Disease, Late Onset, Alzheimer Disease, Early Onset, Mild Cognitive Impairment, Dementia
Register for Updates
A Music-Based Mobile App for People Living With Alzheimer's Disease and Related Dementias (ADRD)
NCT06140342
Recruiting
The purpose of this pilot is to develop a mobile application that detects physiological measures of individuals with Alzheimer's disease and related dementias and triggers auto-play of personalized songs in a wearable device. The investigators will test the feasibility and acceptability of the app. This app may be an important tool to include in daily caregiving in a home setting by extending established benefits of music therapy for people with Alzheimer's disease and related dementias.
Gender:
All
Ages:
All
Trial Updated:
11/21/2023
Locations: Autotune Me, LLC, Brooklyn, New York
Conditions: Dementia, Agitation, Depressive Symptoms
Register for Updates
ToolBox Detect: Low Cost Detection of Cognitive Decline in Primary Care Settings
NCT04852601
Recruiting
Our study objective is to widely implement and evaluate a user-centered, scalable, electronic health record (EHR)-linked strategy for the routine detection of cognitive decline among diverse primary care settings. This strategy, called ToolboxDetect, will provide an efficient and sensitive cognitive screen that can be easily implemented in everyday clinical settings, and is responsive to patient, family, and caregiver concerns for potential symptoms of cognitive decline (CD) and cognitive impair... Read More
Gender:
All
Ages:
65 years and above
Trial Updated:
11/14/2023
Locations: Northwestern University, Chicago, Illinois
Conditions: Cognitive Dysfunction, Dementia
Register for Updates
Paradoxical Lucidity in Severe End-Stage Dementia
NCT05234866
Recruiting
Cognitive decline in dementia is considered irreversible, however episodes of paradoxical lucidity (PL) in severe dementia suggest other mechanisms may be in play. Beyond anecdotal reports of transient PL events occurring in patients predominantly in late-stage dementia and typically lasting anywhere from a few minutes to several hours, little is known about PL. The study team proposes to develop and conduct a mixed methods prospective study of PL during end stage advanced dementia, creating a d... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
11/13/2023
Locations: NYU Langone Health, New York, New York
Conditions: Dementia
Register for Updates
Feasibility of a Systems Approach for Alzheimer's Services Among Latinos Attending Primary Care Practices
NCT04418232
Recruiting
The research team will train primary care practitioners from Kansas City clinics to enhance skills in cultural competence, dementia detection, treatment and referral to a Health Navigator among Latinos 65 and older with dementia. The Health Navigator will provide patient/caregiver dyads referred by Alianza Latina providers with care management, psychosocial support and links to relevant community resources. Outcomes include feasibility and acceptability of 1) PCP training and 2) patient and care... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
10/30/2023
Locations: University of Kansas Medical Center, Kansas City, Kansas
Conditions: Dementia
Register for Updates
Sleep and Circadian Rhythm Biomarkers of Postoperative Delirium
NCT06052397
Recruiting
The goal of this prospective cohort study is to assess potential differences in sleep biomarkers in older adult patients undergoing major orthopedic surgery. The main questions it aims to answer are: To define sleep/circadian biomarkers of delirium (sleep duration, regularity, stability and timing of rhythm) in a prospective observational study. To determine if plasma Alzheimer's disease (AD) pathology/inflammatory burden interacts with or moderates the relationship between a sleep/circadian bi... Read More
Gender:
All
Ages:
70 years and above
Trial Updated:
10/20/2023
Locations: Massachusetts General Hospital, Boston, Massachusetts
Conditions: Delirium, Postoperative, Cognitive Decline, Dementia
Register for Updates