There are currently 104 active clinical trials seeking participants for Dementia research studies. The states with the highest number of trials for Dementia participants are Florida, California, New York and Ontario.
Persons With Dementia and Their Extended Family Caregivers
NCT04863859
Recruiting
Immediate family members shoulder the majority of care responsibilities for persons living with dementia. However, due to various societal changes, elder care responsibilities have expanded to extended family members, including grandchildren, siblings, nieces/nephews, siblings, and step-kin. The main objective of this study is to understand the caregiving journeys of various extended family members involved in dementia care. We aim to learn about caregivers' care management strategies; their us... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/12/2024
Locations: Virginia Polytechnic Institute and State University, Blacksburg, Virginia
Conditions: Dementia, Dementia Alzheimers, Neuro-Degenerative Disease, Dementia of Alzheimer Type, Dementia Severe
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TabCAT Brain Health Assessment in Primary Care
NCT06090578
Recruiting
Efficient and user-friendly paradigms to detect cognitive impairment, including dementia are needed in primary care. The TabCAT Brain Health Assessment accurately detects cognitive impairment via an appealing tablet interface with automated scoring and EMR integration. This study will evaluate the effectiveness of the paradigm on detection rates and other brain health outcomes via a pragmatic cluster randomized trial in 26 Kaiser Southern California primary care clinics.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/27/2024
Locations: Kaiser Permanente Southern California Department of Research & Evaluation, Pasadena, California
Conditions: Mild Cognitive Impairment, Dementia
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Non-invasive Brain Stimulation for Cognitive and Motor Dysfunction in Dementia
NCT05661084
Recruiting
This project aims to examine the efficacy of remote, caregiver-led tES/brain stimulation intervention targeted to improve memory, mobility, and executive functioning among older adults with mild cognitive impairment or mild dementia.
Gender:
ALL
Ages:
55 years and above
Trial Updated:
06/26/2024
Locations: Hinda and Arthur Marcus Institute for Aging Research, Boston, Massachusetts
Conditions: Dementia, Memory Loss, Alzheimer Disease, Executive Dysfunction, Mobility Limitation
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Care Coordination System for People With Dementia
NCT04308512
Recruiting
Dementia, a chronic disease of aging, is characterized by progressive cognitive decline that interferes with independent functioning. The medical, psychological, social and functional sequelae of dementia cause great stress to patients, their caregivers, and their family. The investigator proposes to examine effectivness of a home-based care coordination and management device, called Care4AD to help caregivers effectively coordinate, manage, and improve dementia care.
Gender:
ALL
Ages:
65 years and above
Trial Updated:
06/21/2024
Locations: Baylor College of Medicine, Houston, Texas +1 locations
Conditions: Alzheimer Disease, Dementia, Dementia Alzheimers
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Apolipoprotein E (APOE) Genotype Effects on Triglycerides and Blood Flow in the Human Brain
NCT04692441
Recruiting
High fat feeding (HFF) increases the risk of Alzheimer's disease (AD) but individuals who carry the AD risk gene E4 paradoxically improve after acute HFF. The investigators propose to further study this phenomenon with a clinical study to assess cerebral blood flow which can be measured by a technique called arterial spin labeling (ASL) on an MRI and is tightly related to brain metabolism.
Gender:
ALL
Ages:
55 years and above
Trial Updated:
05/22/2024
Locations: University of Washington Medical Center, Seattle, Washington
Conditions: Alzheimer Disease, Dementia
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New IDEAS: Imaging Dementia-Evidence for Amyloid Scanning Study
NCT04426539
Recruiting
New IDEAS is an observational, open-label, longitudinal cohort study designed to address the requirements of the CED provisions of the NCD on beta-amyloid PET. Building on the initial Imaging Dementia-Evidence for Amyloid Scanning (IDEAS) study, New IDEAS will evaluate the association between amyloid PET and patient-centered outcomes in an expanded and more ethnoracially and clinically diverse group of Medicare participants presenting with cognitive impairment.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/15/2024
Locations: Full list of Active Sites and Imaging Facilities, Philadelphia, Pennsylvania
Conditions: Alzheimer's Disease, Dementia, Mild Cognitive Impairment
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Enhancing Sleep Quality for Nursing Home Residents With Dementia - R33 Phase
NCT05820919
Recruiting
This study seeks to improve clinical outcomes for an important, growing, and vulnerable population-nursing home residents with Alzheimer's disease or related dementias-by testing an evidence-based intervention to improve these residents' sleep. It will also examine the implementation and sustainment of this intervention.
Gender:
ALL
Ages:
50 years and above
Trial Updated:
03/11/2024
Locations: Vivage/Beecan Corporation, Lakewood, Colorado +2 locations
Conditions: Alzheimer Disease, Dementia, Sleep Disorder, Sleep Disturbance
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Alzheimer's Disease Genetics Study
NCT00064870
Recruiting
The purpose of the Alzheimer's Disease Genetics Study is to identify the genes that are responsible for causing Alzheimer's Disease (AD). One of the ways in which the risk factor genes for late onset AD can be investigated is by identifying and collecting genetic material from families with multiple members diagnosed with AD or dementia.
Gender:
ALL
Ages:
All
Trial Updated:
03/07/2024
Locations: Participants are being recruited from all over the United States, Multiple Locations, Indiana
Conditions: Alzheimer Disease, Late Onset Alzheimer Disease, Dementia
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Trial to Reduce Antimicrobial Use in Nursing Home Residents With Alzheimer's Disease and Other Dementias 2.0
NCT05950607
Recruiting
The goal of this pragmatic cluster randomized clinical trial is to compare management of suspected infection in nursing home residents with dementia The main questions it aims to answer whether residents with dementia in nursing homes randomized to use a multicomponent intervention to optimize suspected infection management ( versus usual care) use less antibiotics and fewer burdensome interventions.
Gender:
ALL
Ages:
Between 60 years and 106 years
Trial Updated:
02/27/2024
Locations: Hebrew SeniorLife, Boston, Massachusetts
Conditions: Dementia, Alzheimer Disease, Infections
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OCT Angiography and NRAI in Dementia
NCT03761381
Recruiting
The primary goals of this study are to use optical coherence tomography (OCT) angiography (blood vessel mapping) to: 1. Detect retinal blood vessel and blood flow changes in participants with dementia. 2. Detect amyloid protein deposits in the retinas of participants with dementia.
Gender:
ALL
Ages:
55 years and above
Trial Updated:
02/08/2024
Locations: Oregon Health & Science University, Portland, Oregon
Conditions: Alzheimer Disease, Dementia, Mild Cognitive Impairment
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Stories in the Moment: Dance Program for People Living With Dementia
NCT06221202
Recruiting
This study is designed to evaluate the impact on the quality of life and wellbeing of a person-centered online dance program on people living with dementia or MCI and care partners. The duration of the study will be 1 year. Each participant in the study will be followed for approximately 4 months. The study includes joining a weekly 1-hour dance program online on Zoom for 12 weeks. Prior and after the dance program, participants will meet with the research coordinator to answer some questionnai... Read More
Gender:
ALL
Ages:
50 years and above
Trial Updated:
01/14/2024
Locations: Online, New York, New York
Conditions: Dementia, Mild Cognitive Impairment, Alzheimer Disease, Lewy Body Disease, Frontotemporal Dementia, Vascular Dementia
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A Music-Based Mobile App for People Living With Alzheimer's Disease and Related Dementias (ADRD)
NCT06140342
Recruiting
The purpose of this pilot is to develop a mobile application that detects physiological measures of individuals with Alzheimer's disease and related dementias and triggers auto-play of personalized songs in a wearable device. The investigators will test the feasibility and acceptability of the app. This app may be an important tool to include in daily caregiving in a home setting by extending established benefits of music therapy for people with Alzheimer's disease and related dementias.
Gender:
ALL
Ages:
All
Trial Updated:
11/21/2023
Locations: Autotune Me, LLC, Brooklyn, New York
Conditions: Dementia, Agitation, Depressive Symptoms
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