There are currently 125 active clinical trials seeking participants for Dementia research studies. The states with the highest number of trials for Dementia participants are Florida, California, New York and Pennsylvania.
Clinical Applications of Advanced Ophthalmic Imaging
NCT03135327
Recruiting
The purpose of this study is to determine the clinical application of advanced ophthalmic imaging devices such as optical coherence tomography (OCT), retinal function imager (RFI), slit-lamp biomicroscopy (SLB), PERG in diseased eyes and normal controls. There are two phases in this study. The first phase is an observational phase which studies the eye in various conditions. The second phase is an interventional phase which studies the changes in the eyes after taking an over-the-counter medica... Read More
Gender:
All
Ages:
Between 18 years and 99 years
Trial Updated:
09/12/2023
Locations: Bascom Palmer Eye Institute, Miami, Florida
Conditions: Multiple Sclerosis, Dry Eye Syndromes, Diabetic Retinopathy, Presbyopia, Myopia, Dementia
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Cultural Adaptation of a Behavioral Intervention for Latino Caregivers
NCT04633408
Recruiting
The overall objectives of the proposed research are to: (i) develop a prototype of a smartphone application (app) that can deliver culturally adapted STAR-C training to Latino caregivers, and (ii) understand the extent to which a STAR-C app is acceptable and potentially effective among Latino caregivers. Achieving these objectives will lay the groundwork for a future full-scale trial to test the STAR-C app with Latino caregivers. This study aims to: Adapt the STAR-C training to increase cultura... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
08/15/2023
Locations: Alzheimer's Association, Washington State Chapter, Lynnwood, Washington +1 locations
Conditions: Alzheimer Disease, Dementia
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Alzheimer Prevention Trials (APT) Webstudy
NCT03638583
Recruiting
The goal of the Alzheimer Prevention Trials (APT) Webstudy is to accelerate enrollment for Alzheimer's disease (AD) clinical trials by identifying and tracking individuals who may be at higher risk for developing AD dementia.
Gender:
All
Ages:
Between 50 years and 85 years
Trial Updated:
08/09/2023
Locations: Https://Www.Aptwebstudy.Org, San Diego, California
Conditions: Alzheimer Disease, Dementia
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Cognitive Outcomes of Brain Stimulation As a Later-in-Life Treatment
NCT05564715
Recruiting
This is a pilot study being done to attempt to improve episodic memory problems in persons with mild cognitive impairment (MCI) or dementia. The pre-supplemental motor area (preSMA) and dorsal anterior cingulate cortex (dACC) have been shown to play a role in episodic memory and language retrieval. Prior studies have suggested that neurostimulation targeting this region can improve episodic memory and word recall. The purpose of this study is to examine the efficacy of high-definition transcrani... Read More
Gender:
All
Ages:
55 years and above
Trial Updated:
08/07/2023
Locations: University of Texas Southwestern Medical Center, Dallas, Texas
Conditions: Mild Cognitive Impairment, Dementia, Amnestic Mild Cognitive Impairment - aMCI
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Alzheimer's Prevention Registry: A Program to Accelerate Enrollment Into Studies
NCT02022943
Recruiting
The Alzheimer's Prevention Registry (www.endALZnow.org) will collect contact and demographic information on individuals. The objective is to provide information the latest news and advances in Alzheimer's prevention research, and to inform enrollees about research studies in their community. Enrolled individuals will receive regular email communications. As research studies become available, individuals will be notified via email with information as to how proceed should they be interested. Regi... Read More
Gender:
All
Ages:
Between 18 years and 110 years
Trial Updated:
08/02/2023
Locations: Banner Alzheimer's Institute, Phoenix, Arizona
Conditions: Alzheimer's Disease, Dementia
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Home-based Neuromodulation to Target Depression And Memory Symptoms in Older Adults
NCT05976659
Recruiting
This project aims to explore the feasibility and effects of a symptom-specific, brain-circuit-based, home-based neuromodulation therapy for addressing mood and memory symptoms in older adults with major depressive disorder (MDD) in the context of dementia.
Gender:
All
Ages:
55 years and above
Trial Updated:
07/27/2023
Locations: Hinda and Arthur Marcus Institute for Aging Research, Boston, Massachusetts
Conditions: Major Depressive Disorder, Alzheimer Disease, Dementia, Nervous System Diseases, Memory Disorders, Depressive Disorder
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Priorities Aligned Deprescribing for Persons Living With Dementia and Their Caregiver
NCT05970315
Recruiting
The purpose of this study is to compare patient priorities care (PPC) and usual care (UC) patients to identify differences in post-encounter medication changes, treatment burden (TBQ), and shared decision making in Older Patient Assessment of Chronic Illness Care (OPACIC), to understand PPC participant's sense-making and communication approaches related to deprescribing decisions in relation to the identified health priorities and to identify and categorize adverse drug withdrawal events (ADWEs)
Gender:
All
Ages:
55 years and above
Trial Updated:
07/24/2023
Locations: The University of Texas Health Science Center at Houston, Houston, Texas
Conditions: Dementia
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New IDEAS: Imaging Dementia-Evidence for Amyloid Scanning Study
NCT04426539
Recruiting
New IDEAS is an observational, open-label, longitudinal cohort study designed to address the requirements of the CED provisions of the NCD on beta-amyloid PET. Building on the initial Imaging Dementia-Evidence for Amyloid Scanning (IDEAS) study, New IDEAS will evaluate the association between amyloid PET and patient-centered outcomes in an expanded and more ethnoracially and clinically diverse group of Medicare participants presenting with cognitive impairment.
Gender:
All
Ages:
18 years and above
Trial Updated:
07/18/2023
Locations: Full list of Active Sites and Imaging Facilities, Philadelphia, Pennsylvania
Conditions: Alzheimer's Disease, Dementia, Mild Cognitive Impairment
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Tennessee Alzheimer's Project
NCT05372172
Recruiting
The primary objective of the Vanderbilt Alzheimer's Disease Research Center (VADRC) is to provide local and national researchers with access to a well-characterized and diverse clinical cohort, including participant referrals, biosamples, clinical data, and neuroimaging data. The VADRC Clinical Core will create an infrastructure to support research efforts of both local and national investigator studies to develop early detection, prevention, and treatment strategies for Alzheimer's disease. The... Read More
Gender:
All
Ages:
60 years and above
Trial Updated:
06/30/2023
Locations: Vanderbilt University Medical Center, Nashville, Tennessee
Conditions: Aging, Alzheimer Disease, Biomarker, Cognitive Dysfunction, Mild Cognitive Impairment, Dementia, Cognition
Register for Updates
Cognitive Reserve and Response to Speech-Language Intervention in Bilingual Speakers With Primary Progressive Aphasia
NCT05741853
Recruiting
Difficulties with speech and language are the first and most notable symptoms of primary progressive aphasia (PPA). While there is evidence that demonstrates positive effects of speech-language treatment for individuals with PPA who only speak one language (monolinguals), there is a significant need for investigating the effects of treatment that is optimized for bilingual speakers with PPA. This stage 2 efficacy clinical trial seeks to establish the effects of culturally and linguistically tail... Read More
Gender:
All
Ages:
40 years and above
Trial Updated:
06/28/2023
Locations: University of Texas at Austin, Austin, Texas +2 locations
Conditions: Primary Progressive Aphasia, Dementia, Dementia, Frontotemporal, Alzheimer Disease, Neurodegenerative Diseases, Frontotemporal Lobar Degeneration, Apraxia, Motor, Dysarthria, Communication Disorders, Language Disorders, Speech Disorders, Neurocognitive Disorders, Aphasia, Bilingual Aphasia
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BioFINDER-Brown: Examination of Alzheimer's Disease Biomarkers
NCT05457998
Recruiting
This research study aims to examine biomarkers of Alzheimer's disease as early as possible which could potentially be a screening tool for the general population. This observational study will take place at the Memory and Aging Program at Butler Hospital. The study will enroll up to 200 cognitively healthy subjects aged 50 to 80 years with ongoing recruitment and enrollment for 2 years, and subject participation lasting approximately 4 years. Disclosure of AD risk assessments will be an optional... Read More
Gender:
All
Ages:
Between 50 years and 80 years
Trial Updated:
06/26/2023
Locations: Butler Hospital Memory and Aging Program, Providence, Rhode Island
Conditions: Alzheimer Disease, Mild Cognitive Impairment, Dementia
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MEMORI Corps: Activity-based Companion Care for Dementia
NCT03896711
Recruiting
This is a single blind, intention-to-treat, randomized controlled trial design to evaluate the feasibility and efficacy of a 12-week, evidence-based, individualized MEMORI Corps program delivered by trained older volunteers (n=80) to community-living PWD/CG dyads (n=240). Eligible PWD/CG dyads will be randomized to receive 12-weeks intervention group (n=120), or 12-week augmented waitlist control group (n=120) followed by 12-weeks of intervention. Eligible volunteers will be randomized to 12 mon... Read More
Gender:
All
Ages:
Between 18 years and 115 years
Trial Updated:
06/23/2023
Locations: Johns Hopkins University, Baltimore, Maryland
Conditions: Alzheimer Disease, Dementia
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