There are currently 126 active clinical trials seeking participants for Dementia research studies. The states with the highest number of trials for Dementia participants are Florida, California, New York and Maryland.
Priorities Aligned Deprescribing for Persons Living With Dementia and Their Caregiver
NCT05970315
Recruiting
The purpose of this study is to compare patient priorities care (PPC) and usual care (UC) patients to identify differences in post-encounter medication changes, treatment burden (TBQ), and shared decision making in Older Patient Assessment of Chronic Illness Care (OPACIC), to understand PPC participant's sense-making and communication approaches related to deprescribing decisions in relation to the identified health priorities and to identify and categorize adverse drug withdrawal events (ADWEs)
Gender:
All
Ages:
55 years and above
Trial Updated:
07/24/2023
Locations: The University of Texas Health Science Center at Houston, Houston, Texas
Conditions: Dementia
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Tennessee Alzheimer's Project
NCT05372172
Recruiting
The primary objective of the Vanderbilt Alzheimer's Disease Research Center (VADRC) is to provide local and national researchers with access to a well-characterized and diverse clinical cohort, including participant referrals, biosamples, clinical data, and neuroimaging data. The VADRC Clinical Core will create an infrastructure to support research efforts of both local and national investigator studies to develop early detection, prevention, and treatment strategies for Alzheimer's disease. The... Read More
Gender:
All
Ages:
60 years and above
Trial Updated:
06/30/2023
Locations: Vanderbilt University Medical Center, Nashville, Tennessee
Conditions: Aging, Alzheimer Disease, Biomarker, Cognitive Dysfunction, Mild Cognitive Impairment, Dementia, Cognition
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Cognitive Reserve and Response to Speech-Language Intervention in Bilingual Speakers With Primary Progressive Aphasia
NCT05741853
Recruiting
Difficulties with speech and language are the first and most notable symptoms of primary progressive aphasia (PPA). While there is evidence that demonstrates positive effects of speech-language treatment for individuals with PPA who only speak one language (monolinguals), there is a significant need for investigating the effects of treatment that is optimized for bilingual speakers with PPA. This stage 2 efficacy clinical trial seeks to establish the effects of culturally and linguistically tail... Read More
Gender:
All
Ages:
40 years and above
Trial Updated:
06/28/2023
Locations: University of Texas at Austin, Austin, Texas +2 locations
Conditions: Primary Progressive Aphasia, Dementia, Dementia, Frontotemporal, Alzheimer Disease, Neurodegenerative Diseases, Frontotemporal Lobar Degeneration, Apraxia, Motor, Dysarthria, Communication Disorders, Language Disorders, Speech Disorders, Neurocognitive Disorders, Aphasia, Bilingual Aphasia
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BioFINDER-Brown: Examination of Alzheimer's Disease Biomarkers
NCT05457998
Recruiting
This research study aims to examine biomarkers of Alzheimer's disease as early as possible which could potentially be a screening tool for the general population. This observational study will take place at the Memory and Aging Program at Butler Hospital. The study will enroll up to 200 cognitively healthy subjects aged 50 to 80 years with ongoing recruitment and enrollment for 2 years, and subject participation lasting approximately 4 years. Disclosure of AD risk assessments will be an optional... Read More
Gender:
All
Ages:
Between 50 years and 80 years
Trial Updated:
06/26/2023
Locations: Butler Hospital Memory and Aging Program, Providence, Rhode Island
Conditions: Alzheimer Disease, Mild Cognitive Impairment, Dementia
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MEMORI Corps: Activity-based Companion Care for Dementia
NCT03896711
Recruiting
This is a single blind, intention-to-treat, randomized controlled trial design to evaluate the feasibility and efficacy of a 12-week, evidence-based, individualized MEMORI Corps program delivered by trained older volunteers (n=80) to community-living PWD/CG dyads (n=240). Eligible PWD/CG dyads will be randomized to receive 12-weeks intervention group (n=120), or 12-week augmented waitlist control group (n=120) followed by 12-weeks of intervention. Eligible volunteers will be randomized to 12 mon... Read More
Gender:
All
Ages:
Between 18 years and 115 years
Trial Updated:
06/23/2023
Locations: Johns Hopkins University, Baltimore, Maryland
Conditions: Alzheimer Disease, Dementia
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3D Team Care for Cognitively Vulnerable Older Adults
NCT02945085
Recruiting
This study addresses how to achieve better outcomes for cognitively vulnerable community-dwelling older adults and their families. Cognitive vulnerability means living with dementia, depression, and/or a recent episode of delirium (the 3Ds). The investigators will test the effectiveness of a team care model focused on the 3Ds (Home Based Care Team) guided by nurse practitioners with expertise in geriatrics and geriatric psychiatry. Specific aims are to determine Home Based Care Team effects on h... Read More
Gender:
All
Ages:
65 years and above
Trial Updated:
06/22/2023
Locations: UConn Center on Aging, Farmington, Connecticut
Conditions: Dementia, Depression, Delirium
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Using Technology to Support Care Partners for Persons With Alzheimer's Disease: Tele-STELLA
NCT04627662
Recruiting
The purpose of this study is to test a revised psychoeducational intervention to help Care Partners for family members with dementia understand and reduce the distressing behaviors that come with progressive dementia. Tele-STELLA (Support via TEchnology: Living and Learning with Advancing Alzheimer's disease and related dementias) is a multicomponent videoconference-based intervention designed to facilitate effective management of behavioral and psychological symptoms common to the later stages... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
06/22/2023
Locations: Oregon Health and Science University, Layton Aging and Alzheimer's Disease Center, Portland, Oregon
Conditions: Dementia, Alzheimer Disease, Caregiver Burnout, Family Members
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The Brain Health Study: A Pragmatic, Patient-Centered Trial
NCT05905796
Recruiting
The eRADAR Brain Health Study seeks to refine and test a novel, low-cost strategy for increasing dementia detection within primary care.
Gender:
All
Ages:
65 years and above
Trial Updated:
06/06/2023
Locations: UCSF Primary Care at China Basin, San Francisco, California +2 locations
Conditions: Dementia, Alzheimer Disease
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DECIDE: Dyads and Families
NCT05139290
Recruiting
The purpose of this study is to design and test a decision-making program that is tailored to support adult daughters making healthcare decisions for their parents who are living with memory loss to improve the quality of life of African American families. There are two phases of this research study. The first phase will collect information by surveys and/or interviews. The surveys and interviews will ask questions about demographics (e.g., age, race/ethnicity), culture, health, family dynamics... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
06/02/2023
Locations: Zeta Phi Beta Sorority, Inc., Washington, District of Columbia +3 locations
Conditions: Dementia, Alzheimer Disease, Caregiver Burden
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Persons With Dementia and Their Extended Family Caregivers
NCT04863859
Recruiting
Immediate family members shoulder the majority of care responsibilities for persons living with dementia. However, due to various societal changes, elder care responsibilities have expanded to extended family members, including grandchildren, siblings, nieces/nephews, siblings, and step-kin. The main objective of this study is to understand the caregiving journeys of various extended family members involved in dementia care. We aim to learn about caregivers' care management strategies; their us... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/23/2023
Locations: Virginia Polytechnic Institute and State University, Blacksburg, Virginia
Conditions: Dementia, Dementia Alzheimers, Neuro-Degenerative Disease, Dementia of Alzheimer Type, Dementia Severe
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Physical Activity, Alzheimer's Disease and Cognition Relative to APOE Genotype
NCT03876314
Recruiting
Physical activity and Alzheimer's disease (PAAD-2) is a randomized control trial that will assess the effects of exercise on middle-aged (40-65 years) cognitively normal adults who have a heightened risk of Alzheimer's disease (AD) due to family history (FH+). The investigators will also assess the extent to which this effect is moderated by apolipoprotein epsilon-4 (APOE4) carrier status, and will gather critical new experimental evidence on the use of physical activity to improve cognitive per... Read More
Gender:
All
Ages:
Between 40 years and 65 years
Trial Updated:
05/12/2023
Locations: University of North Carolina-Greensboro, Greensboro, North Carolina
Conditions: Healthy, Dementia, Alzheimer Disease, Physical Activity
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Dementia and Diabetes Prevention Program
NCT04141878
Recruiting
This is a multicenter, randomized 2-arm clinical trial of two lifestyle interventions varying in intensity and format, in 400 older African American and non-Hispanic whites at increased risk of cognitive decline and dementia in the East San Francisco Bay Area. The trial will include two lifestyle interventions that differ in intensity and format: Aerobic Exercise (AEx) Intervention that involves aerobic activities with in-class walking workouts and tutorials and carried out at the East Oakland... Read More
Gender:
All
Ages:
60 years and above
Trial Updated:
05/10/2023
Locations: University of California, Davis Alzheimer's Disease Center, Walnut Creek, California
Conditions: Diabetes, Dementia
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