Remote Balance Training for Individuals With Dementia
NCT05558215
Recruiting
Individuals with dementia (IwDs) fall more and are more seriously injured in falls than their age-matched, cognitively intact peers. An accessible and sustainable fall prevention program would be of great value. Using remote technology has become commonplace during the COVID-19 pandemic, and Marymount University's new Center for Optimal Aging plans to use this technology to bring a web-based version of a well-established and accepted evidence-based fall prevention intervention, the Otago Exercis... Read More
Gender:
All
Ages:
60 years and above
Trial Updated:
10/19/2023
Locations: Marymount University, Arlington, Virginia
Conditions: Dementia
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Persons With Dementia and Their Extended Family Caregivers
NCT04863859
Recruiting
Immediate family members shoulder the majority of care responsibilities for persons living with dementia. However, due to various societal changes, elder care responsibilities have expanded to extended family members, including grandchildren, siblings, nieces/nephews, siblings, and step-kin. The main objective of this study is to understand the caregiving journeys of various extended family members involved in dementia care. We aim to learn about caregivers' care management strategies; their us... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/23/2023
Locations: Virginia Polytechnic Institute and State University, Blacksburg, Virginia
Conditions: Dementia, Dementia Alzheimers, Neuro-Degenerative Disease, Dementia of Alzheimer Type, Dementia Severe
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Effects of THC-Free CBD Oil on Agitation in Patients With Alzheimer's Disease
NCT04436081
Recruiting
This is a randomized, double-blinded, placebo-controlled, crossover trial that aims to 1) determine the efficacy of THC-free cannabidiol (CBD oil) in reducing the severity of agitation among participants and 2) determine whether THC-free CBD oil can reduce the burden on caregivers and increase the participants' quality of life.
Gender:
All
Ages:
Between 50 years and 90 years
Trial Updated:
02/15/2023
Locations: Eastern Virginia Medical School, Norfolk, Virginia
Conditions: Alzheimer Disease, Dementia, Major Neurocognitive Disorder With Aggressive Behavior
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TRC-PAD Program: In-Clinic Trial-Ready Cohort
NCT04004767
Recruiting
The purpose of the TRC-PAD study is to develop a large, well-characterized, biomarker-confirmed, trial-ready cohort to facilitate rapid enrollment into AD prevention trials utilizing the APT Webstudy and subsequent referral to in-clinic evaluation and biomarker confirmation. Participants with known biomarker status may have direct referral to the Trial-Ready Cohort. If you are interested in being selected for the TRC-PAD study, you should first enroll in the APT Webstudy (https://www.aptwebstud... Read More
Gender:
All
Ages:
Between 50 years and 85 years
Trial Updated:
11/30/2023
Locations: University of Alabama, Birmingham, Alabama +50 locations
Conditions: Preclinical Alzheimer's Disease, Prodromal Alzheimer's Disease, Alzheimer Disease, Dementia
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Alzheimer's Disease Neuroimaging Initiative 4
NCT05617014
Recruiting
Since its launch in 2004, the overarching aim of the Alzheimer's Disease Neuroimaging Initiative (ADNI) Study has been to validate biomarkers for Alzheimer's disease (AD) clinical trials. ADNI4 continues the previously funded ADNI1, ADNI-GO, ADNI2, and ADNI3 studies that have combined public/private collaborations between academia and industry to determine the relationships between the clinical, cognitive, imaging, genetic and biochemical biomarker characteristics of the entire spectrum of AD.
Gender:
All
Ages:
Between 55 years and 90 years
Trial Updated:
11/30/2023
Locations: Banner Alzheimer's Institute, Phoenix, Arizona +17 locations
Conditions: Mild Cognitive Impairment, Alzheimer Disease, Dementia
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Assessment of DeMentia Nutrition Intervention Needs Among Care Recipients and carEgivers
NCT05536830
Recruiting
Nutrition is critical for disease prevention and brain health. Malnutrition and weight loss often affect persons with Alzheimer's dementia (PWD), worsening overall health and dementia. Informal caregivers (usually family members) perform many nutrition-related tasks as part of daily care such as food preparation and feeding. Limited research, however, suggests informal caregivers experience high rates of caregiver burden, malnutrition and low health literacy. More research is needed to uncover t... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
11/27/2023
Locations: University of Kansas Medical Center, Kansas City, Kansas
Conditions: Dementia
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A Music-Based Mobile App for People Living With Alzheimer's Disease and Related Dementias (ADRD)
NCT06140342
Recruiting
The purpose of this pilot is to develop a mobile application that detects physiological measures of individuals with Alzheimer's disease and related dementias and triggers auto-play of personalized songs in a wearable device. The investigators will test the feasibility and acceptability of the app. This app may be an important tool to include in daily caregiving in a home setting by extending established benefits of music therapy for people with Alzheimer's disease and related dementias.
Gender:
All
Ages:
All
Trial Updated:
11/21/2023
Locations: Autotune Me, LLC, Brooklyn, New York
Conditions: Dementia, Agitation, Depressive Symptoms
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In-Home Technology for Caregivers of People With Dementia and Mild Cognitive Impairment: Rural Homes
NCT05159583
Recruiting
This study aims to develop, evaluate, and commercialize an in-home supportive technology that is designed to alleviate anxiety, burden, and loneliness in spousal and familial caregivers of individuals with Alzheimer's disease, other dementias, or mild cognitive impairment in rural homes.
Gender:
All
Ages:
18 years and above
Trial Updated:
11/17/2023
Locations: University of California, Berkeley, Berkeley, California
Conditions: Dementia, Mild Cognitive Impairment, Alzheimer Disease
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In-Home Technology for Caregivers of People With Dementia and Mild Cognitive Impairment: Wearables
NCT05159557
Recruiting
This study aims to develop, evaluate, and commercialize an in-home supportive technology that is designed to alleviate anxiety, burden, and loneliness in spousal and familial caregivers of individuals with Alzheimer's disease, other dementias, or mild cognitive impairment by integrating wearable devices (e.g., Apple Watches).
Gender:
All
Ages:
18 years and above
Trial Updated:
11/17/2023
Locations: University of California, Berkeley, Berkeley, California
Conditions: Dementia, Mild Cognitive Impairment, Alzheimer Disease
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PET Imaging of Neuroinflammation in Neurodegenerative Diseases Via a Novel TSPO Radioligand
NCT03958630
Recruiting
Background: Aging-related progressive neurological disorders include frontotemporal dementia, Lou Gehrig s disease, and Alzheimer s disease. Little is known about what causes these disorders. Brain inflammation may be involved. Researchers want to see if scans using radioactive drugs can show brain inflammation. Objective: To see if the drug [11C]ER176 can show inflammation in the brain in people with certain progressive neurological disorders compared to healthy adults. Also to find genes th... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
11/16/2023
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Dementia
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Adapting the Shed-MEDS Deprescribing Intervention to Dementia Care in Assisted Living
NCT05956665
Recruiting
This single-arm pilot study will evaluate the effects of an intervention to reduce exposure to unnecessary or potentially harmful medications among residents with dementia living in an assisted living facility. The goal of the intervention is to safely deprescribe medications (defined by dose reductions and stopped medications), based on a combination of clinical criteria and resident/surrogate preferences. The investigators will evaluate the effects of the intervention on the total number of me... Read More
Gender:
All
Ages:
65 years and above
Trial Updated:
11/16/2023
Locations: Abe's Garden Community, Nashville, Tennessee
Conditions: Polypharmacy, Dementia, Quality of Life
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The Care Ecosystem Consortium Effectiveness Study
NCT05669365
Recruiting
The Care Ecosystem is an accessible, remotely delivered team-based dementia care model, designed to add value for patients, providers and payers in complex organizational and reimbursement structures. Care is delivered via the phone and web by unlicensed Care Team Navigators, who are trained and supervised by a team of dementia specialists with nursing, social work, and pharmacy expertise. The evidence base to date suggests that the Care Ecosystem improves outcomes important to people with demen... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
11/15/2023
Locations: University of California, San Francisco, San Francisco, California +5 locations
Conditions: Dementia, Dementia, Vascular, Dementia With Lewy Bodies, Dementia Alzheimers, Frontotemporal Dementia
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