There are currently 126 active clinical trials seeking participants for Dementia research studies. The states with the highest number of trials for Dementia participants are Florida, California, New York and Maryland.
Persons With Dementia and Their Extended Family Caregivers
NCT04863859
Recruiting
Immediate family members shoulder the majority of care responsibilities for persons living with dementia. However, due to various societal changes, elder care responsibilities have expanded to extended family members, including grandchildren, siblings, nieces/nephews, siblings, and step-kin. The main objective of this study is to understand the caregiving journeys of various extended family members involved in dementia care. We aim to learn about caregivers' care management strategies; their us... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/23/2023
Locations: Virginia Polytechnic Institute and State University, Blacksburg, Virginia
Conditions: Dementia, Dementia Alzheimers, Neuro-Degenerative Disease, Dementia of Alzheimer Type, Dementia Severe
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Effects of THC-Free CBD Oil on Agitation in Patients With Alzheimer's Disease
NCT04436081
Recruiting
This is a randomized, double-blinded, placebo-controlled, crossover trial that aims to 1) determine the efficacy of THC-free cannabidiol (CBD oil) in reducing the severity of agitation among participants and 2) determine whether THC-free CBD oil can reduce the burden on caregivers and increase the participants' quality of life.
Gender:
All
Ages:
Between 50 years and 90 years
Trial Updated:
02/15/2023
Locations: Eastern Virginia Medical School, Norfolk, Virginia
Conditions: Alzheimer Disease, Dementia, Major Neurocognitive Disorder With Aggressive Behavior
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PET Imaging of Cyclooxygenases in Neurodegenerative Brain Disease
NCT04396873
Recruiting
Background: About 5 million adults in the U.S. have Alzheimer s disease or another adult-onset neurodegenerative disorder. Many studies have found that inflammation in the brain contributes to these diseases. Researchers want to find a better way to measure this inflammation. Objective: To learn whether COX-1 and/or COX-2 is elevated in the brains of individuals with neurodegenerative brain disease compared to healthy volunteers. Eligibility: Adults age 18 years and older in good general he... Read More
Gender:
All
Ages:
Between 18 years and 99 years
Trial Updated:
06/21/2024
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Dementia, Alzheimer's Disease, ALS, Parkinson's Disease
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Alzheimer's Disease Neuroimaging Initiative 4
NCT05617014
Recruiting
Since its launch in 2004, the overarching aim of the Alzheimer's Disease Neuroimaging Initiative (ADNI) Study has been to validate biomarkers for Alzheimer's disease (AD) clinical trials. ADNI4 continues the previously funded ADNI1, ADNI-GO, ADNI2, and ADNI3 studies that have combined public/private collaborations between academia and industry to determine the relationships between the clinical, cognitive, imaging, genetic and biochemical biomarker characteristics of the entire spectrum of AD.
Gender:
All
Ages:
Between 55 years and 90 years
Trial Updated:
06/19/2024
Locations: University of Alabama at Birmingham, Birmingham, Alabama +43 locations
Conditions: Mild Cognitive Impairment, Alzheimer Disease, Dementia
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Interventions for Patients With Alzheimer's Disease and Dysphagia
NCT03682081
Recruiting
The overall purpose of this project is to develop effective dysphagia rehabilitative interventions for patients with Alzheimer's Disease and related dementias at risk for pneumonia development.
Gender:
All
Ages:
Between 50 years and 99 years
Trial Updated:
06/18/2024
Locations: University of Wisconsin-Madison, Madison, Wisconsin
Conditions: Dementia, Dysphagia, Alzheimer Disease
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Stress Management Toolkit for People Living With Dementia and Their Care Partners
NCT05465551
Recruiting
The purpose of this study is to develop a prototype of a home-based, dyadic tangible toolkit comprised of simple tools to help people living with dementia (PLWD) and their care partners manage stress at home. A human-centered design approach will be used to develop and user-test a prototype of a dyadic, tangible stress-management toolkit with and for PLWD and their care partners; and to explore the feasibility of collecting several stress-related outcomes. A total of 4 focus groups (n=3-4 dyads... Read More
Gender:
All
Ages:
21 years and above
Trial Updated:
06/18/2024
Locations: Caregiver and dementia community support organizations, Durham, North Carolina
Conditions: Dementia, Stress, Caregiver Burden
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Ferritin and Iron Burden in SAH sIRB
NCT03754725
Recruiting
Ruptured cerebral aneurysms lead to subarachnoid hemorrhage (SAH),that has a high morbidity and mortality rate, the severity of which is predicted by the "Hunt-Hess grade" (HHG). SAH leads to iron (Fe) and hemoglobin (Hb) accumulation in the brain, which is toxic for neurons. Ferritin (iron reported in the brian) and iron overload leads to brain atrophy, specifically in the mesial temporal lobe (hippocampus, impairing patients' cognition. It is estimated that 50% of survivors have cognitive def... Read More
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
06/18/2024
Locations: Univesity of Iowa Hospital and Clinics, Iowa City, Iowa +1 locations
Conditions: SAH, Dementia
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Reducing Risk of Dementia Through Deprescribing
NCT04270474
Recruiting
A cluster-randomized controlled trial (RCT) called "Reducing Risk of Dementia through Deprescribing" (R2D2) to evaluate the impact of a deprescribing intervention on important cognitive and safety outcomes.
Gender:
All
Ages:
65 years and above
Trial Updated:
06/18/2024
Locations: Eskenazi Health, Indianapolis, Indiana +2 locations
Conditions: Dementia, Alzheimer Disease, Late Onset
Register for Updates
Family Caregiver Online Survey (Dementia and Swallowing Difficulties)
NCT06471660
Recruiting
The Family Caregiver Survey is a one-time, 30-minute, online survey for people living with and caring for a family member with dementia. The goal of this research is to explore the needs of family caregivers, specifically when it comes to managing swallowing difficulties (dysphagia).
Gender:
All
Ages:
18 years and above
Trial Updated:
06/17/2024
Locations: Remote study offered by the University of Oregon, Eugene, Oregon
Conditions: Dementia, Dysphagia, Dementia Alzheimers, Dementia, Vascular, Dementia, Mixed, Dementia With Lewy Bodies, Dementia Frontal, Dementia, Mild, Dementia Moderate, Dementia Severe, Parkinson Disease Dementia, Dementia Frontotemporal
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Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults
NCT04262206
Recruiting
PREVENTABLE is a multi-center, randomized, parallel group, placebo-controlled superiority study. Participants will be randomized 1:1 to atorvastatin 40 mg or placebo. This large study conducted in community-dwelling older adults without cardiovascular disease (CVD) or dementia will demonstrate the benefit of statins for reducing the primary composite of death, dementia, and persistent disability and secondary composites including mild cognitive impairment (MCI) and cardiovascular events.
Gender:
All
Ages:
75 years and above
Trial Updated:
06/14/2024
Locations: University of Alabama at Birmingham, Birmingham, Alabama +102 locations
Conditions: Cognitive Impairment, Mild, Dementia, Cardiovascular Diseases
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Minnesota Inclusive LTSS for LGBTQ Seniors
NCT05530590
Recruiting
This study is designed to help improve the care of sexual and gender minority (SGM) with Alzheimer's Disease and Alzheimer's Disease Related Dementia (AD/ADRD) in long-term services and supports (LTSS) by training the state's LTSS workforce in SGM culturally responsive care. The randomized controlled trial will rigorously test the effects of an in person versus an online training program on improving SGM culturally responsive care with a waitlist control.
Gender:
All
Ages:
18 years and above
Trial Updated:
06/13/2024
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Alzheimer Disease, Dementia
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Patient Priorities Care Among Persons Living With Mild Cognitive Impairment and Dementia
NCT06001775
Recruiting
The goal of this pragmatic, embedded clinical trial is to analyze the implementation of Patient Priorities Care in primary care and geriatrics clinics with patients living with dementia or mild cognitive impairment. This study aims are: demonstrate the feasibility of using the electronic health record to identify a diverse cohort of eligible patient and patient-care partner dyads who will engage in a Patient Priorities Care conversation with a trained facilitator. demonstrate feasibility of pra... Read More
Gender:
All
Ages:
40 years and above
Trial Updated:
06/12/2024
Locations: Regenstrief Institute, Inc., Indianapolis, Indiana
Conditions: Dementia, Mild Cognitive Impairment
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