There are currently 128 active clinical trials seeking participants for Dementia research studies. The states with the highest number of trials for Autism participants are Florida, California, New York and Pennsylvania.
Safety and Modulation of ABCC9 Pathways by Nicorandil for the Treatment of Hippocampal Sclerosis of Aging
NCT04120766
Recruiting
Widespread recognition of the current and projected impact of the dementia epidemic has spurred research into novel drug discovery efforts. It is well recognized by most that Alzheimer's disease is not the only form of dementia and that beginning to turn attention to other disease states is critically important in order to alleviate this burden on the elderly population today This proposal seeks to further progress in this area through the repurposing an existing drug therapy as a potential trea... Read More
Gender:
All
Ages:
75 years and above
Trial Updated:
01/30/2024
Locations: University of Kentucky, Lexington, Kentucky
Conditions: Dementia, Mild Cognitive Impairment
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Testing the Pain Clinical Practice Guideline
NCT05858996
Recruiting
There are evidence based processes for assessment and management of pain using pharmacologic and nonpharmacological approaches. These were reviewed and included within the Pain Management Clinical Practice Guideline (Pain Management CPG) recently developed by AMDA: The Society for Post-Acute and Long-Term Care Medicine. There are, however, many challenges to translating the use of Clinical Practice Guidelines into clinical settings. To overcome these challenges we developed and previously tested... Read More
Gender:
All
Ages:
65 years and above
Trial Updated:
01/21/2024
Locations: Charles E Smilth Life Community, Rockville, Maryland
Conditions: Pain, Dementia
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Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults
NCT04262206
Recruiting
PREVENTABLE is a multi-center, randomized, parallel group, placebo-controlled superiority study. Participants will be randomized 1:1 to atorvastatin 40 mg or placebo. This large study conducted in community-dwelling older adults without cardiovascular disease (CVD) or dementia will demonstrate the benefit of statins for reducing the primary composite of death, dementia, and persistent disability and secondary composites including mild cognitive impairment (MCI) and cardiovascular events.
Gender:
All
Ages:
75 years and above
Trial Updated:
01/17/2024
Locations: University of Alabama at Birmingham, Birmingham, Alabama +102 locations
Conditions: Cognitive Impairment, Mild, Dementia, Cardiovascular Diseases
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User-Led Meaningful Activity and Early-Stage Dementia
NCT05159869
Recruiting
Neuropsychiatric symptoms are the most difficult, distressing, and burdensome aspects of dementia care and a catalyst for long-term care placement. Intervention studies have largely focused on helping caregivers manage these symptoms. However, little has been done with regard to persons at the earliest stages of dementia, nor have persons with dementia played a direct and active, central role in helping to design intervention studies. This study focuses on building, pilot testing, and evaluating... Read More
Gender:
All
Ages:
60 years and above
Trial Updated:
01/16/2024
Locations: Johns Hopkins School of Nursing, Baltimore, Maryland
Conditions: Dementia
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Evaluating the Efficacy of the Pain Identification and Communication Toolkit
NCT06168604
Recruiting
This study will evaluate the Pain Identification and Communication Toolkit (PICT), a multicomponent intervention for caregivers of people with Alzheimer's disease and related dementias (ADRD). PICT provides training in observational pain assessment and coaching in effective pain communication techniques. It will recruit participants from programs of all-inclusive care for the elderly (PACE). The investigators hypothesize that PICT will help caregivers to recognize and communicate about pain in t... Read More
Gender:
All
Ages:
21 years and above
Trial Updated:
01/16/2024
Locations: Weill Cornell Medicine, New York, New York
Conditions: Caregiver Burden, Cognitive Impairment, Dementia, Alzheimer Disease, Pain, Chronic
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Stories in the Moment: Dance Program for People Living With Dementia
NCT06221202
Recruiting
This study is designed to evaluate the impact on the quality of life and wellbeing of a person-centered online dance program on people living with dementia or MCI and care partners. The duration of the study will be 1 year. Each participant in the study will be followed for approximately 4 months. The study includes joining a weekly 1-hour dance program online on Zoom for 12 weeks. Prior and after the dance program, participants will meet with the research coordinator to answer some questionnai... Read More
Gender:
All
Ages:
50 years and above
Trial Updated:
01/14/2024
Locations: Online, New York, New York
Conditions: Dementia, Mild Cognitive Impairment, Alzheimer Disease, Lewy Body Disease, Frontotemporal Dementia, Vascular Dementia
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Remote Game-based Exercise Program for Cognitive and Motor Function Improvement
NCT05235113
Recruiting
As our population ages, more older adults face motor-cognitive declines, increasing their risk of falls and fear of falling. Exercise is an effective way to maintain cognitive function, as supported by recent studies. However, those with poor motor and cognitive abilities often struggle to visit rehabilitation centers, leading to high dropout rates and low adherence to unsupervised programs. A remote exercise program tailored for individuals with cognitive impairments is urgently needed to prese... Read More
Gender:
All
Ages:
50 years and above
Trial Updated:
01/10/2024
Locations: Baylor College of Medicine, Houston, Texas
Conditions: Mild Cognitive Impairment, Dementia, Cognitive Impairment, Memory Loss
Register for Updates
A Technology-Driven Intervention to Improve Early Detection and Management of Cognitive Impairment
NCT05723523
Recruiting
Most experts advocate for early detection of cognitive impairment (CI) so that patients and caregivers can be prepared for making difficult decisions and to improve quality of life, but studies show that screening alone isn't sufficient to change clinician actions related to early detection. Using predictive modelling developed with machine learning methods and sophisticated clinical decision support (CDS) tools, it is possible to identify patients at elevated risk for CI and make it much easier... Read More
Gender:
All
Ages:
65 years and above
Trial Updated:
01/05/2024
Locations: HealthPartners, Bloomington, Minnesota +1 locations
Conditions: Dementia, Cognitive Impairment
Register for Updates
HEARS-SLP: Providing SLP-Delivered Hearing Health Care to Individuals With Cognitive Impairment
NCT06008782
Recruiting
Building upon the HEARS audiologist-community health worker (CHW) model, this study intervention will be delivered by a speech-language pathologist (SLP). The primary objective of the study is to develop and test an affordable and accessible hearing rehabilitative intervention that will be delivered by a SLP to individuals with cognitive impairment.
Gender:
All
Ages:
Between 60 years and 100 years
Trial Updated:
01/04/2024
Locations: Johns Hopkins Medicine, Baltimore, Maryland
Conditions: Hearing Loss, Dementia, Cognitive Impairment
Register for Updates
Financial Incentives and Recruitment to the APT Webstudy
NCT06033066
Recruiting
This single-blind, three-arm, randomized, controlled trial will assess the impact of messages and financial incentives on the enrollment of demographically diverse individuals to the Alzheimer Prevention Trials (APT) Webstudy. The APT Webstudy is a novel, online registry that employs quarterly cognitive testing using validated platforms. The APT Webstudy implements fully remote assessments, coordinated by the Alzheimer's Therapeutic Research Institute (ATRI) under USC IRB #HS-17-00746. The purpo... Read More
Gender:
All
Ages:
50 years and above
Trial Updated:
12/19/2023
Locations: Contra Costa Health Plan, Martinez, California
Conditions: Alzheimer Disease, Dementia, Preclinical Alzheimer's Disease, Prodromal Alzheimer's Disease
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Treatment of Stress and Anxiety in MCI/Mild ADRD
NCT05748613
Recruiting
The goal of this clinical trial is to test the effectiveness of a computerized anxiety sensitivity treatment (CAST) compared to a health education control (HEC) in older adults with mild cognitive impairment (MCI) or mild Alzheimer's Disease and related dementias (ADRD) and their care partners. The main questions it aims to answer are: Efficacy of CAST in reducing anxiety and related symptoms among those with MCI/mild ADRD Efficacy of CAST in reducing care partner burden among care partners of... Read More
Gender:
All
Ages:
60 years and above
Trial Updated:
12/13/2023
Locations: Anxiety and Behavioral Health Clinic, Tallahassee, Florida +2 locations
Conditions: Anxiety, Mild Cognitive Impairment, Alzheimer Disease, Dementia
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Quality Improvement and Clinical Utility PrecivityAD2(TM) Clinician Survey
NCT06025877
Recruiting
There is a major unmet need for timely, non-invasive, and low-burden evaluation of patients presenting with mild cognitive impairment (MCI) and dementia. MCI impacts 12-18% of people in the United States over age 60 years (Alzheimer's Association. Mild Cognitive Impairment (MCI) available at https://www.alz.org/alzheimers-dementia/what-is-dementia/related_conditions/mild-cognitive-impairment. Accessed August 16, 2022). MCI does not substantially interfere with daily activities, although complex... Read More
Gender:
All
Ages:
55 years and above
Trial Updated:
12/13/2023
Locations: UCSF Memory and Aging Center, San Francisco, California +6 locations
Conditions: Alzheimer Disease, Mild Cognitive Impairment, Dementia, Cognitive Decline, Cognitive Impairment, Memory Impairment
Register for Updates