There are currently 128 active clinical trials seeking participants for Dementia research studies. The states with the highest number of trials for Autism participants are Florida, California, New York and Pennsylvania.
Early Cognitive Intervention in Delirium
NCT04740567
Recruiting
This is a randomized control trial to determine if early cognitive training and rehabilitation improve 4-month cognition in hospitalized older (>=65 years old) delirious patients with and without Alzheimer's disease and related dementias. Enrolled patients will be randomized to receive cognitive intervention versus usual care at a 1:2 allocation ratio. Patients assigned to the cognitive intervention group will receive cognitive training daily during hospitalization and cognitive rehabilitation w... Read More
Gender:
All
Ages:
65 years and above
Trial Updated:
12/12/2023
Locations: Tennessee Valley Healthcare System - Nashville Veteran Affairs Hospital, Nashville, Tennessee +1 locations
Conditions: Delirium, Cognitive Decline, Dementia
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Genetic Studies in Familial Dementia
NCT04680013
Recruiting
The purpose of this study is to identify genetic factors that contribute to or cause dementia (loss of memory) and related disorders across all ages and ethnic groups. This includes a number of neurological diseases such as early and late-onset Alzheimer disease, mild cognitive impairment, and other dementias.
Gender:
All
Ages:
18 years and above
Trial Updated:
12/02/2023
Locations: University of Miami, Miami, Florida
Conditions: Dementia of Alzheimer Type, Alzheimer Disease, Late Onset, Alzheimer Disease, Early Onset, Mild Cognitive Impairment, Dementia
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The Active Mind Trial: An Adaptive Randomized Trial to Improve Function and Delay Dementia
NCT04171323
Recruiting
Older adults at risk for dementia show a variety of cognitive deficits, which can be ameliorated by different cognitive training (CT) exercises. The best combination of CT exercises is unknown. The aim is to discover the most efficacious combination of CT exercises as compared to cognitive stimulation (which will serve as a stringent, active control) to modify the functional trajectories of older adults' with MCI, who are at high risk for dementia. The primary objective of the U01 phase was to d... Read More
Gender:
All
Ages:
Between 55 years and 89 years
Trial Updated:
11/28/2023
Locations: University of California San Francisco, San Francisco, California +4 locations
Conditions: Age-related Cognitive Decline, Mild Cognitive Impairment, Dementia
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Assessment of DeMentia Nutrition Intervention Needs Among Care Recipients and carEgivers
NCT05536830
Recruiting
Nutrition is critical for disease prevention and brain health. Malnutrition and weight loss often affect persons with Alzheimer's dementia (PWD), worsening overall health and dementia. Informal caregivers (usually family members) perform many nutrition-related tasks as part of daily care such as food preparation and feeding. Limited research, however, suggests informal caregivers experience high rates of caregiver burden, malnutrition and low health literacy. More research is needed to uncover t... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
11/27/2023
Locations: University of Kansas Medical Center, Kansas City, Kansas
Conditions: Dementia
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A Music-Based Mobile App for People Living With Alzheimer's Disease and Related Dementias (ADRD)
NCT06140342
Recruiting
The purpose of this pilot is to develop a mobile application that detects physiological measures of individuals with Alzheimer's disease and related dementias and triggers auto-play of personalized songs in a wearable device. The investigators will test the feasibility and acceptability of the app. This app may be an important tool to include in daily caregiving in a home setting by extending established benefits of music therapy for people with Alzheimer's disease and related dementias.
Gender:
All
Ages:
All
Trial Updated:
11/21/2023
Locations: Autotune Me, LLC, Brooklyn, New York
Conditions: Dementia, Agitation, Depressive Symptoms
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In-Home Technology for Caregivers of People With Dementia and Mild Cognitive Impairment: Rural Homes
NCT05159583
Recruiting
This study aims to develop, evaluate, and commercialize an in-home supportive technology that is designed to alleviate anxiety, burden, and loneliness in spousal and familial caregivers of individuals with Alzheimer's disease, other dementias, or mild cognitive impairment in rural homes.
Gender:
All
Ages:
18 years and above
Trial Updated:
11/17/2023
Locations: University of California, Berkeley, Berkeley, California
Conditions: Dementia, Mild Cognitive Impairment, Alzheimer Disease
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In-Home Technology for Caregivers of People With Dementia and Mild Cognitive Impairment: Wearables
NCT05159557
Recruiting
This study aims to develop, evaluate, and commercialize an in-home supportive technology that is designed to alleviate anxiety, burden, and loneliness in spousal and familial caregivers of individuals with Alzheimer's disease, other dementias, or mild cognitive impairment by integrating wearable devices (e.g., Apple Watches).
Gender:
All
Ages:
18 years and above
Trial Updated:
11/17/2023
Locations: University of California, Berkeley, Berkeley, California
Conditions: Dementia, Mild Cognitive Impairment, Alzheimer Disease
Register for Updates
The Care Ecosystem Consortium Effectiveness Study
NCT05669365
Recruiting
The Care Ecosystem is an accessible, remotely delivered team-based dementia care model, designed to add value for patients, providers and payers in complex organizational and reimbursement structures. Care is delivered via the phone and web by unlicensed Care Team Navigators, who are trained and supervised by a team of dementia specialists with nursing, social work, and pharmacy expertise. The evidence base to date suggests that the Care Ecosystem improves outcomes important to people with demen... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
11/15/2023
Locations: University of California, San Francisco, San Francisco, California +5 locations
Conditions: Dementia, Dementia, Vascular, Dementia With Lewy Bodies, Dementia Alzheimers, Frontotemporal Dementia
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ToolBox Detect: Low Cost Detection of Cognitive Decline in Primary Care Settings
NCT04852601
Recruiting
Our study objective is to widely implement and evaluate a user-centered, scalable, electronic health record (EHR)-linked strategy for the routine detection of cognitive decline among diverse primary care settings. This strategy, called ToolboxDetect, will provide an efficient and sensitive cognitive screen that can be easily implemented in everyday clinical settings, and is responsive to patient, family, and caregiver concerns for potential symptoms of cognitive decline (CD) and cognitive impair... Read More
Gender:
All
Ages:
65 years and above
Trial Updated:
11/14/2023
Locations: Northwestern University, Chicago, Illinois
Conditions: Cognitive Dysfunction, Dementia
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Paradoxical Lucidity in Severe End-Stage Dementia
NCT05234866
Recruiting
Cognitive decline in dementia is considered irreversible, however episodes of paradoxical lucidity (PL) in severe dementia suggest other mechanisms may be in play. Beyond anecdotal reports of transient PL events occurring in patients predominantly in late-stage dementia and typically lasting anywhere from a few minutes to several hours, little is known about PL. The study team proposes to develop and conduct a mixed methods prospective study of PL during end stage advanced dementia, creating a d... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
11/13/2023
Locations: NYU Langone Health, New York, New York
Conditions: Dementia
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Self-Care for Dementia Caregivers
NCT05309577
Recruiting
The Self-care for Dementia Caregivers Study is a behavioral health intervention that uses digital monitoring tools and motivational health coaching to help caregivers of persons with dementia engage in a regular routine of self-care. Participants wear an apple watch for the objective collection of sleep-wake rhythms. They receive personalized feedback on their sleep-wake rhythms via a new app. Health coaches call participants weekly, for 6 weeks to help participants meet their health/sleep goals... Read More
Gender:
All
Ages:
Between 50 years and 99 years
Trial Updated:
11/06/2023
Locations: University of Pittsburgh, Pittsburgh, Pennsylvania
Conditions: Aging, Mental Disorder, Eating, Healthy, Physical Inactivity, Prodromal Symptoms, Sleep, Alzheimer Disease, Dementia, Circadian Rhythm Disorders
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Feasibility of a Systems Approach for Alzheimer's Services Among Latinos Attending Primary Care Practices
NCT04418232
Recruiting
The research team will train primary care practitioners from Kansas City clinics to enhance skills in cultural competence, dementia detection, treatment and referral to a Health Navigator among Latinos 65 and older with dementia. The Health Navigator will provide patient/caregiver dyads referred by Alianza Latina providers with care management, psychosocial support and links to relevant community resources. Outcomes include feasibility and acceptability of 1) PCP training and 2) patient and care... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
10/30/2023
Locations: University of Kansas Medical Center, Kansas City, Kansas
Conditions: Dementia
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