There are currently 126 active clinical trials seeking participants for Dementia research studies. The states with the highest number of trials for Dementia participants are Florida, California, New York and Pennsylvania.
Combating Alzheimer's Through Sleep and Exercise
NCT04855630
Recruiting
The purpose of this research is to see how sleep and exercise affects dementia risk over time.
Gender:
All
Ages:
Between 45 years and 80 years
Trial Updated:
02/29/2024
Locations: University of Miami Hospitals, Miami, Florida
Conditions: Alzheimer Disease, Dementia
Register for Updates
Trial to Reduce Antimicrobial Use in Nursing Home Residents With Alzheimer's Disease and Other Dementias 2.0
NCT05950607
Recruiting
The goal of this pragmatic cluster randomized clinical trial is to compare management of suspected infection in nursing home residents with dementia The main questions it aims to answer whether residents with dementia in nursing homes randomized to use a multicomponent intervention to optimize suspected infection management ( versus usual care) use less antibiotics and fewer burdensome interventions.
Gender:
All
Ages:
Between 60 years and 106 years
Trial Updated:
02/27/2024
Locations: Hebrew SeniorLife, Boston, Massachusetts
Conditions: Dementia, Alzheimer Disease, Infections
Register for Updates
Biomarkers for Vascular Contributions to Cognitive Impairment and Dementia Consortium
NCT06284213
Recruiting
Biomarkers for Vascular Contributions to Cognitive Impairment and Dementia (MarkVCID) is an NIH-funded consortium dedicated to finding biomarkers involved in age-related thinking and memory problems. Alzheimer's disease and other dementias leave signatures on brain scans or in the blood called biomarkers. The MarkVCID study will measure a panel of candidate biomarkers in 1800 participants and watch them closely to see what they tell us about changes in brain function and risk of memory loss. Ag... Read More
Gender:
All
Ages:
Between 60 years and 90 years
Trial Updated:
02/27/2024
Locations: University of Southern California, Los Angeles, California +16 locations
Conditions: Cognitive Impairment, Dementia
Register for Updates
Dominantly Inherited Alzheimer Network Trial: An Opportunity to Prevent Dementia. A Study of Potential Disease Modifying Treatments in Individuals With a Type of Early Onset Alzheimer's Disease Caused by a Genetic Mutation (DIAN-TU)
NCT05269394
Recruiting
To assess the safety, tolerability, biomarker, cognitive, and clinical efficacy of investigational products in participants with an Alzheimer's disease-causing mutation by determining if treatment with the study drug improves disease-related biomarkers and slows the rate of progression of cognitive or clinical impairment.
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
02/20/2024
Locations: University of Alabama in Birmingham, Birmingham, Alabama +37 locations
Conditions: Alzheimers Disease, Dementia, Alzheimers Disease, Familial
Register for Updates
Home Alone: An Intervention for People With Cognitive Impairment Who Live Alone
NCT05746390
Recruiting
The goal of this clinical trial is to evaluate a program for adults who live alone and have some cognitive impairment (CI) to see if it is useful and acceptable. This program aims to help older adults with cognitive impairment who live alone to be engaged and active, as well as safe at home. The investigators want to see how useful this program is and how it can be improved. The specific aims are: Specific Aim 1: Develop and Adapt Home Alone to Prepare for Pilot Testing. Specific Aim 2: Pilot... Read More
Gender:
All
Ages:
55 years and above
Trial Updated:
02/16/2024
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Cognitive Impairment, Dementia, Memory Loss
Register for Updates
Web-based Cognitive Behavioral Treatment for Insomnia in Dementia Caregivers
NCT04632628
Recruiting
Over the next 30 years, more than 10 million persons living with dementia in the United States will receive care at home from an unpaid and untrained family caregiver. At home care is preferred by caregivers and persons with dementia alike, but increases the caregiver's risk of insomnia and related negative health outcomes, including depression, anxiety, cognitive disturbances and poor quality of life. Cognitive behavioral therapy for insomnia (CBT-I) is a highly effective and established eviden... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
02/15/2024
Locations: University of Missouri, Columbia, Missouri
Conditions: Insomnia Chronic, Dementia
Register for Updates
Patient-Centered Dementia Care Practice Coaching Intervention
NCT06249204
Recruiting
The goal of this clinical trial is to compare staff outcomes in long-term care communities who participate in the intervention versus those who do not. The main questions it aims to answer are: 1. Is employee satisfaction impacted by the intervention and 2. Is dementia care confidence impacted by the intervention. Participants will include monthly coaching visits for the intervention group and completion of surveys pre, immediately post and three-months post. Researchers will compare the interve... Read More
Gender:
All
Ages:
Between 18 years and 100 years
Trial Updated:
02/12/2024
Locations: Alzheimer's Association, Chicago, Illinois
Conditions: Dementia, Alzheimer Disease
Register for Updates
OCT Angiography and NRAI in Dementia
NCT03761381
Recruiting
The primary goals of this study are to use optical coherence tomography (OCT) angiography (blood vessel mapping) to: Detect retinal blood vessel and blood flow changes in participants with dementia. Detect amyloid protein deposits in the retinas of participants with dementia.
Gender:
All
Ages:
55 years and above
Trial Updated:
02/08/2024
Locations: Oregon Health & Science University, Portland, Oregon
Conditions: Alzheimer Disease, Dementia, Mild Cognitive Impairment
Register for Updates
Reducing Inappropriate Medication Use for BPSD
NCT06040502
Recruiting
Investigators previously developed a low-cost, practical, patient- and care partner-centric, evidence-informed systematic approach (the "DICE Approach" or DICE), to assess and manage behavioral and psychological symptoms of dementia (BPSD). The goals of this proposal are to refine and test the application of DICE in primary care clinics by: (a) using existing clinic staff to deliver DICE; and (b) using the electronic medical record to identify and recruit PLWD (persons living with dementia) and... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
02/07/2024
Locations: University of California, Davis, Sacramento, California
Conditions: Dementia
Register for Updates
Primary Care Detection of Cognitive Impairment Leveraging Health & Consumer Technologies in Underserved Communities: The MyCog Trial
NCT05607732
Recruiting
Our study intends to offer 'real world' evidence of a viable, sustainable means to mobilize primary care via a comprehensive strategy for detecting cognitive impairment and dementias, advancing next steps for referral, and participating in the care planning and management of affected patients and caregivers. We will conduct a clinic-randomized, pragmatic trial testing the effectiveness and fidelity of our NIH Toolbox-derived paradigm to improve early detection and management of cognitive impairm... Read More
Gender:
All
Ages:
45 years and above
Trial Updated:
02/06/2024
Locations: Oak Street Health, Chicago, Illinois
Conditions: Dementia, Cognitive Impairment, Cognitive Decline, Alzheimer Disease
Register for Updates
Safety and Modulation of ABCC9 Pathways by Nicorandil for the Treatment of Hippocampal Sclerosis of Aging
NCT04120766
Recruiting
Widespread recognition of the current and projected impact of the dementia epidemic has spurred research into novel drug discovery efforts. It is well recognized by most that Alzheimer's disease is not the only form of dementia and that beginning to turn attention to other disease states is critically important in order to alleviate this burden on the elderly population today This proposal seeks to further progress in this area through the repurposing an existing drug therapy as a potential trea... Read More
Gender:
All
Ages:
75 years and above
Trial Updated:
01/30/2024
Locations: University of Kentucky, Lexington, Kentucky
Conditions: Dementia, Mild Cognitive Impairment
Register for Updates
Evaluating the Efficacy of the Pain Identification and Communication Toolkit
NCT06168604
Recruiting
This study will evaluate the Pain Identification and Communication Toolkit (PICT), a multicomponent intervention for caregivers of people with Alzheimer's disease and related dementias (ADRD). PICT provides training in observational pain assessment and coaching in effective pain communication techniques. It will recruit participants from programs of all-inclusive care for the elderly (PACE). The investigators hypothesize that PICT will help caregivers to recognize and communicate about pain in t... Read More
Gender:
All
Ages:
21 years and above
Trial Updated:
01/16/2024
Locations: Weill Cornell Medicine, New York, New York
Conditions: Caregiver Burden, Cognitive Impairment, Dementia, Alzheimer Disease, Pain, Chronic
Register for Updates