There are currently 112 active clinical trials seeking participants for Dementia research studies. The states with the highest number of trials for Dementia participants are Florida, California, New York and Ontario.
Testing the Pain Clinical Practice Guideline
NCT05858996
Recruiting
There are evidence based processes for assessment and management of pain using pharmacologic and nonpharmacological approaches. These were reviewed and included within the Pain Management Clinical Practice Guideline (Pain Management CPG) recently developed by AMDA: The Society for Post-Acute and Long-Term Care Medicine. There are, however, many challenges to translating the use of Clinical Practice Guidelines into clinical settings. To overcome these challenges we developed and previously tested... Read More
Gender:
ALL
Ages:
60 years and above
Trial Updated:
12/11/2024
Locations: Future Care Coldspring, Baltimore, Maryland +4 locations
Conditions: Pain, Dementia
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HEARS-SLP: Providing SLP-Delivered Hearing Health Care to Individuals With Cognitive Impairment
NCT06008782
Recruiting
Building upon the HEARS audiologist-community health worker (CHW) model, this study intervention will be delivered by a speech-language pathologist (SLP). The primary objective of the study is to develop and test an affordable and accessible hearing rehabilitative intervention that will be delivered by a SLP to individuals with cognitive impairment.
Gender:
ALL
Ages:
Between 60 years and 100 years
Trial Updated:
12/05/2024
Locations: Johns Hopkins Medicine, Baltimore, Maryland
Conditions: Hearing Loss, Dementia, Cognitive Impairment
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The Active Mind Trial: An Adaptive Randomized Trial to Improve Function and Delay Dementia
NCT04171323
Recruiting
Older adults at risk for dementia show a variety of cognitive deficits, which can be ameliorated by different cognitive training (CT) exercises. The best combination of CT exercises is unknown. The aim is to discover the most efficacious combination of CT exercises as compared to cognitive stimulation (which will serve as a stringent, active control) to modify the functional trajectories of older adults' with MCI, who are at high risk for dementia. The primary objective of the U01 phase was to d... Read More
Gender:
ALL
Ages:
Between 55 years and 89 years
Trial Updated:
12/05/2024
Locations: University of California San Francisco, San Francisco, California +3 locations
Conditions: Age-related Cognitive Decline, Mild Cognitive Impairment, Dementia
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A Spanish-language Caregiver-Enabled Care Program
NCT06631144
Recruiting
The purpose of the study is to develop and test the feasibility of a nonmedical digital health intervention, the Spanish-language Caregiver-Enabled Care Program (CECP), with Spanish-speaking caregivers of persons with dementia (PWD). CECP is a nonmedical digital population health intervention that provides personalized education, proactive 1:1 human coaching, and remote monitoring, all delivered via a dedicated tablet shipped to the caregiver's home at no cost to the caregiver or PWD. For this s... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/03/2024
Locations: Ceresti Health, Carlsbad, California
Conditions: Dementia, Dementia Alzheimers, Alzheimer Disease, Caregiver, Caregiver Burden
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Assessing Cognitive Decline at Home
NCT06704971
Recruiting
Neuropsychiatric symptoms (NPS) refer to a range of mental and emotional issues that can be observed through how patients move, perform daily tasks, and express feelings on their faces. In this study, the investigators want to find ways to accurately and unobtrusively track these symptoms in people's homes over time. Our goals are to note when these symptoms happen, predict potential problems, and gather clear data to help doctors make accurate diagnoses. To do this, the investigators will firs... Read More
Gender:
ALL
Ages:
65 years and above
Trial Updated:
11/25/2024
Locations: Clinical Excellence Research Center, Palo Alto, California
Conditions: Mild Cognitive Impairment, Mild Dementia, Dementia Alzheimers, Dementia, Memory Impairment, NPS
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ADRC Clinical Cohort (Alzheimer's Disease)
NCT06703541
Recruiting
The purpose of the study is to establish a clinical cohort for the Duke/UNC Alzheimer's Disease Research Center (ADRC). The cohort will be composed of subjects ages 25 to 44 at enrollment with normal cognition and subjects ages 45 to 80 at enrollment with normal cognition, mild cognitive impairment, or a dementia diagnosis. Initial data including demographics, medical and family history, physical exam, and neuropsychological testing will be obtained. Participants will be asked to contribute a bl... Read More
Gender:
ALL
Ages:
Between 25 years and 80 years
Trial Updated:
11/21/2024
Locations: Duke University, Durham, North Carolina
Conditions: Alzheimer Disease, Mild Cognitive Impairment, Dementia
Register for Updates
Caregiving While Black: LIVE
NCT06605391
Recruiting
This study will test the psychoeducation course, Caregiving while Black - Learning In Vital Engagement (LIVE), among Black caregivers providing care to persons with dementia. This course aims to enhance Black caregivers' capacity to cope effectively with their caregiving role of navigating care and the world of healthcare in ways that take into consideration the social and cultural context of their unique life experiences.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/19/2024
Locations: Emory University, Nell Hodgson Woodruff School of Nursing, Atlanta, Georgia
Conditions: Dementia
Register for Updates
Evaluating the Efficacy of the Pain Identification and Communication Toolkit
NCT06168604
Recruiting
This study will evaluate the Pain Identification and Communication Toolkit (PICT), a multicomponent intervention for caregivers of people with Alzheimer's disease and related dementias (ADRD). PICT provides training in observational pain assessment and coaching in effective pain communication techniques. It will recruit participants from programs of all-inclusive care for the elderly (PACE) and partnering health care clinics. The investigators hypothesize that PICT will help caregivers to recogn... Read More
Gender:
ALL
Ages:
21 years and above
Trial Updated:
11/18/2024
Locations: Weill Cornell Medicine, New York, New York
Conditions: Caregiver Burden, Cognitive Impairment, Dementia, Alzheimer Disease, Pain, Chronic
Register for Updates
Dementia and Diabetes Prevention Program
NCT04141878
Recruiting
This is a multicenter, randomized 2-arm clinical trial of two lifestyle interventions varying in intensity and format, in 400 older African American and non-Hispanic whites at increased risk of cognitive decline and dementia in the East San Francisco Bay Area. The trial will include two lifestyle interventions that differ in intensity and format: 1. Aerobic Exercise (AEx) Intervention that involves aerobic activities with in-class walking workouts and tutorials and carried out at the East Oakla... Read More
Gender:
ALL
Ages:
60 years and above
Trial Updated:
11/05/2024
Locations: University of California, Davis Alzheimer's Disease Center, Walnut Creek, California
Conditions: Diabetes, Dementia
Register for Updates
Sleep and Circadian Rhythm Biomarkers of Postoperative Delirium
NCT06052397
Recruiting
The goal of this prospective cohort study is to assess potential differences in sleep biomarkers in older adult patients undergoing major orthopedic surgery. The main questions it aims to answer are: 1. To define sleep/circadian biomarkers of delirium (sleep duration, regularity, stability and timing of rhythm) in a prospective observational study. 2. To determine if plasma Alzheimer's disease (AD) pathology/inflammatory burden interacts with or moderates the relationship between a sleep/circad... Read More
Gender:
ALL
Ages:
70 years and above
Trial Updated:
11/04/2024
Locations: Massachusetts General Hospital, Boston, Massachusetts
Conditions: Delirium, Postoperative, Cognitive Decline, Dementia
Register for Updates
Aging Brain Care Virtual Program
NCT06245499
Recruiting
The program involves a virtual intervention to be delivered by RN or SW care coordinators over one year. Every care partner will receive monthly virtual visits during the first 3 months and then quarterly or more depending on assessed need. The intervention relies on a tailored approach in which patient and caregiver needs are identified during visits using validated assessment tools and addressed with standardized protocols. Protocols include management of behavioral/psychological symptoms of d... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/15/2024
Locations: Regenstrief Institute, Inc., Indianapolis, Indiana
Conditions: Dementia, Alzheimer Disease
Register for Updates
Paradoxical Lucidity in Severe End-Stage Dementia
NCT05234866
Recruiting
Cognitive decline in dementia is considered irreversible, however episodes of paradoxical lucidity (PL) in severe dementia suggest other mechanisms may be in play. Beyond anecdotal reports of transient PL events occurring in patients predominantly in late-stage dementia and typically lasting anywhere from a few minutes to several hours, little is known about PL. The study team proposes to develop and conduct a mixed methods prospective study of PL during end stage advanced dementia, creating a d... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/30/2024
Locations: NYU Langone Health, New York, New York
Conditions: Dementia
Register for Updates