There are currently 126 active clinical trials seeking participants for Dementia research studies. The states with the highest number of trials for Dementia participants are Florida, California, New York and Pennsylvania.
Patient Priorities Care Among Persons Living With Mild Cognitive Impairment and Dementia
Recruiting
The goal of this pragmatic, embedded clinical trial is to analyze the implementation of Patient Priorities Care in primary care and geriatrics clinics with patients living with dementia or mild cognitive impairment. This study aims are: demonstrate the feasibility of using the electronic health record to identify a diverse cohort of eligible patient and patient-care partner dyads who will engage in a Patient Priorities Care conversation with a trained facilitator. demonstrate feasibility of pra... Read More
Gender:
All
Ages:
40 years and above
Trial Updated:
06/12/2024
Locations: Regenstrief Institute, Inc., Indianapolis, Indiana
Conditions: Dementia, Mild Cognitive Impairment
Improving the Quality of Dementia Care Through Innovative Redesign of the Memory Care Environment
Recruiting
Research study is being done to demonstrate novel opportunities to transform the way the dementia community is cared for.
Gender:
All
Ages:
Between 65 years and 100 years
Trial Updated:
06/12/2024
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Dementia
Community-based Brain Health Program to Address Dementia Risk
Recruiting
This is a validation study to evaluate the acceptability, feasibility and preliminary efficacy of the Brain Health Program, a multimodal curriculum covering dementia risk factors and evidence-based change interventions. The goal of this study is to evaluate the Brain Health Program in individuals with identified risk factors for the onset of dementia and to prepare for a large-scale efficacy trial in this population.
Gender:
All
Ages:
65 years and above
Trial Updated:
06/10/2024
Locations: YMCA of San Francisco, San Francisco, California
Conditions: Dementia, Alzheimer Disease
Providing Evidence-Based Approaches for Caregiver Stress Study
Recruiting
The purpose of this preliminary study is to examine the effects of adult day service use on subjective and physiological measures of stress in 50 Black informal caregivers for individuals with dementia (IWD). The PI of the proposed study has substantial training in primary data collection and complex-survey secondary data analysis, she also has the fundamental knowledge to investigate how sociocultural and behavioral factors can influence psychosocial stress. The proposed study will enroll parti... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
06/05/2024
Locations: Johns Hopkins University, Baltimore, Maryland
Conditions: Caregiving Stress, Dementia
User-Led Meaningful Activity and Early-Stage Dementia
Recruiting
Neuropsychiatric symptoms are the most difficult, distressing, and burdensome aspects of dementia care and a catalyst for long-term care placement. Intervention studies have largely focused on helping caregivers manage these symptoms. However, little has been done with regard to persons at the earliest stages of dementia, nor have persons with dementia played a direct and active, central role in helping to design intervention studies. This study focuses on building, pilot testing, and evaluating... Read More
Gender:
All
Ages:
60 years and above
Trial Updated:
06/04/2024
Locations: Johns Hopkins School of Nursing, Baltimore, Maryland
Conditions: Dementia
Testing the Pain Clinical Practice Guideline
Recruiting
There are evidence based processes for assessment and management of pain using pharmacologic and nonpharmacological approaches. These were reviewed and included within the Pain Management Clinical Practice Guideline (Pain Management CPG) recently developed by AMDA: The Society for Post-Acute and Long-Term Care Medicine. There are, however, many challenges to translating the use of Clinical Practice Guidelines into clinical settings. To overcome these challenges we developed and previously tested... Read More
Gender:
All
Ages:
65 years and above
Trial Updated:
06/01/2024
Locations: Communicare Ellicott City, Ellicott City, Maryland +2 locations
Conditions: Pain, Dementia
A Study of Different Donanemab (LY3002813) Dosing Regimens in Adults With Early Alzheimer's Disease (TRAILBLAZER-ALZ 6)
Recruiting
This study will investigate different donanemab dosing regimens and their effect on the frequency and severity of ARIA-E in adults with early symptomatic Alzheimer's disease (AD) and explore participant characteristics that might predict risk of ARIA.
Gender:
All
Ages:
Between 60 years and 85 years
Trial Updated:
05/24/2024
Locations: MD First Research - Chandler, Chandler, Arizona +48 locations
Conditions: Alzheimer's Disease, Dementia, Brain Diseases, Central Nervous System Diseases, Nervous System Diseases, Neurodegenerative Diseases, Neurocognitive Disorders, Mental Disorders
Family Involvement Hospital Ethnography
Recruiting
The goal of this observational study is to learn about the role of family members in caring for hospitalized older adults with cognitive impairment. The main questions it aims to answer are: What features of the healthcare system facilitate or hinder family involvement in care from the perspective of patients, families, and healthcare workers? How do hospital leaders understand the facilitators and barriers to family involvement? Data collection will occur via semi-structure interviews, direct... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/23/2024
Locations: Duke Regional Hospital, Durham, North Carolina
Conditions: Dementia
Sleep Enhancement for Older Adults Living With Memory Loss And Their Care Partners
Recruiting
The purpose of this study is to determine if a 6-week videoconference intervention to teach skills to improve sleep is practical, acceptable, and helpful to persons living with memory loss, cognitive impairment, and/or dementia and care partners, individually or together.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/23/2024
Locations: Emory Healthcare System, Atlanta, Georgia
Conditions: Sleep Disturbance, Dementia
Apolipoprotein E (APOE) Genotype Effects on Triglycerides and Blood Flow in the Human Brain
Recruiting
High fat feeding (HFF) increases the risk of Alzheimer's disease (AD) but individuals who carry the AD risk gene E4 paradoxically improve after acute HFF. The investigators propose to further study this phenomenon with a clinical study to assess cerebral blood flow which can be measured by a technique called arterial spin labeling (ASL) on an MRI and is tightly related to brain metabolism.
Gender:
All
Ages:
55 years and above
Trial Updated:
05/22/2024
Locations: University of Washington Medical Center, Seattle, Washington
Conditions: Alzheimer Disease, Dementia
Evaluating a National Person-Centered Training Program to Strengthen the Dementia Care Workforce
Recruiting
This project will compare two training models of an evidence-based online dementia care training program for direct care staff in assisted living to a waitlist control: 1) essentiALZ training and 2) essentiALZ training + Project ECHO. It will examine the extent to which each model is implemented and achieves its intended outcomes to improve staff knowledge and attitudes, change care practices, and improve the wellbeing of staff, residents, and residents' family members. Results will inform next... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/22/2024
Locations: University of North Carolina at Chapel Hill, Chapel Hill, North Carolina
Conditions: Aging, Knowledge, Attitudes, Practice, Long-Term Care, Dementia
Genetic Characterization of Movement Disorders and Dementias
Recruiting
Background: There are two basic types of movement disorders. Some cause excessive movement, some cause slowness or lack of movement. Some of these are caused by mutations in genes. On the other hand, dementia is a condition of declining mental abilities, especially memory. Dementia can occur at any age but becomes more frequent with age. Researchers want to study the genes of families with a history of movement disorders or dementia. They hope to find a genetic cause of these disorders. This ca... Read More
Gender:
All
Ages:
Between 18 years and 120 years
Trial Updated:
05/17/2024
Locations: National Institute of Aging, Clinical Research Unit, Baltimore, Maryland
Conditions: Dementia, Movement Disorder