There are currently 128 active clinical trials seeking participants for Dementia research studies. The states with the highest number of trials for Autism participants are Florida, California, New York and Pennsylvania.
Aging Brain Care Virtual Program
NCT06245499
Recruiting
The program involves a virtual intervention to be delivered by RN or SW care coordinators over one year. Every care partner will receive monthly virtual visits during the first 3 months and then quarterly or more depending on assessed need. The intervention relies on a tailored approach in which patient and caregiver needs are identified during visits using validated assessment tools and addressed with standardized protocols. Protocols include management of behavioral/psychological symptoms of d... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
04/16/2024
Locations: Regenstrief Institute, Inc., Indianapolis, Indiana
Conditions: Dementia, Alzheimer Disease
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Patient Priorities Care Among Persons Living With Mild Cognitive Impairment and Dementia
NCT06001775
Recruiting
The goal of this pragmatic, embedded clinical trial is to analyze the implementation of Patient Priorities Care in primary care and geriatrics clinics with patients living with dementia or mild cognitive impairment. This study aims are: demonstrate the feasibility of using the electronic health record to identify a diverse cohort of eligible patient and patient-care partner dyads who will engage in a Patient Priorities Care conversation with a trained facilitator. demonstrate feasibility of pra... Read More
Gender:
All
Ages:
40 years and above
Trial Updated:
04/16/2024
Locations: Regenstrief Institute, Inc., Indianapolis, Indiana
Conditions: Dementia, Mild Cognitive Impairment
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Coaching Dementia Caregivers to Master Care-Resistant Behavior
NCT05098652
Recruiting
266 family caregivers will be randomly assigned to either immediate intervention or delayed intervention groups. All caregivers will complete baseline surveys and 3 weeks of daily diaries. The immediate intervention group will receive 12 weeks of CuRB-IT. They will complete 3 rounds of 3-week daily diaries followed by an intermittent survey at 12 week intervals for the next 33 weeks. The delayed intervention group will receive 12 weeks of attention, complete 1 round of 3-week daily diaries follo... Read More
Gender:
All
Ages:
Between 18 years and 95 years
Trial Updated:
04/15/2024
Locations: University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Care-resistant Behavior, Dementia
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PET Imaging of Cyclooxygenases in Neurodegenerative Brain Disease
NCT04396873
Recruiting
Background: About 5 million adults in the U.S. have Alzheimer s disease or another adult-onset neurodegenerative disorder. Many studies have found that inflammation in the brain contributes to these diseases. Researchers want to find a better way to measure this inflammation. Objective: To learn whether COX-1 and/or COX-2 is elevated in the brains of individuals with neurodegenerative brain disease compared to healthy volunteers. Eligibility: Adults age 18 years and older in good general he... Read More
Gender:
All
Ages:
Between 18 years and 99 years
Trial Updated:
04/13/2024
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Dementia, Alzheimer's Disease, ALS, Parkinson's Disease
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Neurologic Stem Cell Treatment Study
NCT02795052
Recruiting
This is a human clinical study involving the isolation of autologous bone marrow derived stem cells (BMSC) and transfer to the vascular system and inferior 1/3 of the nasal passages in order to determine if such a treatment will provide improvement in neurologic function for patients with certain neurologic conditions. http://mdstemcells.com/nest/
Gender:
All
Ages:
18 years and above
Trial Updated:
04/12/2024
Locations: MD Stem Cells, Westport, Connecticut +2 locations
Conditions: Neurologic Disorders, Nervous System Diseases, Neurodegenerative Diseases, Neurological Disorders, Stroke, Traumatic Brain Injury, Cadasil, Chronic Traumatic Encephalopathy, Cerebral Infarction, Cerebral Ischemia, Cerebral Stroke, Cerebral Hemorrhage, Parkinson, Multi-System Degeneration, MSA - Multiple System Atrophy, Progressive Supranuclear Palsy, ALS, Amyotrophic Lateral Sclerosis, Neuropathy, Diabetic Neuropathies, Alzheimer Disease, Dementia, Frontotemporal Dementia, Lewy Body Disease, Cognitive Impairment, Lewy Body Variant of Alzheimer Disease
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Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) Diet in Stroke Patients Patients
NCT04337255
Recruiting
To test the effects of a 2- to 3-year intervention of the MIND diet versus usual post-stroke care on cognitive decline, the characteristic feature of dementia, and on brain biomarkers of Alzheimer's Disease (AD) and vascular disease in a Phase Ill randomized controlled trial of 500 patients hospitalized for acute ischemic stroke, aged 55 years or older, and without dementia who are discharged home following hospitalization.
Gender:
All
Ages:
55 years and above
Trial Updated:
04/10/2024
Locations: Rush University Medical Center, Chicago, Illinois
Conditions: Cognitive Decline, Dementia, Vascular, Alzheimer Disease, Dementia, Stroke
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Music Therapy and Social Work Telehealth for Older Adult Well-Being
NCT06219148
Recruiting
This study investigates the benefits of using telehealth services, specifically a combination of music therapy and social work support, to improve the well-being of older adults. Investigators are focusing on outcomes such as reduced loneliness, improved cognition, and how well older adults with and without dementia perceive the quality of the services received. This research is crucial because as the population ages and conditions like Alzheimer's become more prevalent, effective psychosocial i... Read More
Gender:
All
Ages:
65 years and above
Trial Updated:
04/08/2024
Locations: University of Kentucky, Lexington, Kentucky +1 locations
Conditions: Aging Well, Dementia, Telemedicine
Register for Updates
Artificial Intelligence + Care Coach Intervention
NCT05352399
Recruiting
The purpose of this research study is to develop and test an artificial intelligence intervention for emergency department (ED) discharge care transitions experienced by caregivers of older adults with cognitive impairment.
Gender:
All
Ages:
65 years and above
Trial Updated:
04/03/2024
Locations: Yale New Haven Hospital, New Haven, Connecticut
Conditions: Dementia, Caregiver, Emergency Department, Artificial Intelligence, Care Transition
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Community-based Brain Health Program to Address Dementia Risk
NCT05529706
Recruiting
This is a validation study to evaluate the acceptability, feasibility and preliminary efficacy of the Brain Health Program, a multimodal curriculum covering dementia risk factors and evidence-based change interventions. The goal of this study is to evaluate the Brain Health Program in individuals with identified risk factors for the onset of dementia and to prepare for a large-scale efficacy trial in this population.
Gender:
All
Ages:
65 years and above
Trial Updated:
04/03/2024
Locations: YMCA of San Francisco, San Francisco, California
Conditions: Dementia, Alzheimer Disease
Register for Updates
PainChek® US Validation Nursing Home Study
NCT06049732
Recruiting
Pain is common amongst people living with dementia. However, as people's dementia worsens their ability to self-report pain diminishes because of limitations in their cognition and communication abilities. As a result pain in people with moderate to severe dementia often goes under-recognised and undertreated. PainChek® is a technology-enabled, observational pain assessment tool, in the form of a mobile application designed specifically to assist healthcare professionals and professional caregi... Read More
Gender:
All
Ages:
All
Trial Updated:
04/03/2024
Locations: NewAldaya Lifescapes, Cedar Falls, Iowa +4 locations
Conditions: Dementia, Pain
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Adapting the Shed-MEDS Deprescribing Intervention to Dementia Care in Assisted Living
NCT05956665
Recruiting
This single-arm pilot study will evaluate the effects of an intervention to reduce exposure to unnecessary or potentially harmful medications among residents with dementia living in an assisted living facility. The goal of the intervention is to safely deprescribe medications (defined by dose reductions and stopped medications), based on a combination of clinical criteria and resident/surrogate preferences. The investigators will evaluate the effects of the intervention on the total number of me... Read More
Gender:
All
Ages:
65 years and above
Trial Updated:
03/31/2024
Locations: Abe's Garden Community, Nashville, Tennessee
Conditions: Polypharmacy, Dementia, Quality of Life
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NeurostImulation for Cognitive Enhancement in Alzheimer's Disease
NCT04404153
Recruiting
The prevalence of Alzheimer's Disease (AD) is rising, but existing medications provide only modest control of cognitive decline and associated symptoms, and novel therapies are urgently needed. This randomized sham-controlled trial will determine if an innovative low-risk remotely-supervised transcranial Direct Current Stimulation (tDCS) applied over the area of the dorsolateral prefrontal cortex for 30 minutes at the intensity of 2 mA five times per week for 6 months at home can improve cogniti... Read More
Gender:
All
Ages:
60 years and above
Trial Updated:
03/27/2024
Locations: Albert Einstein College of Medicine, Bronx, New York
Conditions: Alzheimer Disease, Dementia
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