Outcomes of Low-Impact Exercise Program for People With Ankle, Knee, and/or Hip Pain
Recruiting
The primary objective of this study is to study how low-impact group exercise classes affect pain scores in patients with knee, hip, and ankle pain when paired with concurrent standard of care dietitian and behavioral health consults.
Gender:
All
Ages:
18 years and above
Trial Updated:
11/28/2023
Locations: Missouri Orthopaedic Institute, Columbia, Missouri
Conditions: Osteoarthritis, Osteoarthritis, Knee, Osteoarthritis, Hip, Osteoarthritis Ankle
Temporary Peripheral Nerve Stimulation System for Osteoarthritis of the Knee
Recruiting
The purpose of this study is to demonstrate the treatment outcomes of patients with chronic knee pain secondary to osteoarthritis that have received a temporary peripheral nerve stimulation system.
Gender:
All
Ages:
Between 21 years and 90 years
Trial Updated:
11/21/2023
Locations: Aurora Health Center, Fond Du Lac, Wisconsin +1 locations
Conditions: Osteoarthritis, Knee, Osteoarthritis
Cemented vs Cementless Persona Keel RCT
Recruiting
The main objective of this study is to evaluate the safety, performance, and clinical benefits of the Persona Keel cementless and cemented knee.
Gender:
All
Ages:
18 years and above
Trial Updated:
11/17/2023
Locations: Centura Health, Westminster, Colorado +4 locations
Conditions: Knee Pain Chronic, Rheumatoid Arthritis, Osteoarthritis, Traumatic Arthritis, Polyarthritis, Avascular Necrosis, Varus Deformity, Valgus Deformity, Flexion Deformity of Knee
Postoperative Hip Precautions After Total Hip Arthroplasty Via the Posterior Approach: A Prospective Randomized Trial
Recruiting
The purpose of this study is to determine if hip precautions, which are instructions that limit functional use of a hip replacement after surgery, affect the rate of dislocation in the first six weeks after primary total hip replacement surgery. The impact of hip precautions on a patient's return to activities of daily living and overall patient satisfaction will also be investigated. The overall cost effectiveness of hip precautions will be determined.
Gender:
All
Ages:
18 years and above
Trial Updated:
11/14/2023
Locations: Rush University Medical Center, Chicago, Illinois
Conditions: Osteoarthritis, Degenerative Joint Disease
The KinematX Midcarpal Total Wrist Arthroplasty Registry
Recruiting
The goal of this observational study is to learn about functional and patient reported outcomes in patient undergoing total wrist replacement with the KinematX total wrist replacement study. The main questions it aims to answer are: What is the range of motion (flexion, extension, radial, ulnar, grip and pinch strength) at 3-, 6-, and 12-months after surgery and yearly up to 10 years among patients having total wrist replacement with the KinematX implant. What are the patient reported outcomes... Read More
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
11/13/2023
Locations: Loma Linda University, Loma Linda, California +3 locations
Conditions: Scapholunate Advanced Collapse (SLAC), Scapholunate Crystalline Advanced Collapse (SCAC), Scaphoid, Trapezium, and Trapezoid Advanced Collapse (STTAC), Carpal Tunnel Syndrome (CTS), Kienbock's Disease of Adults, Radial Malunion, Ulnar Translocation, Post Traumatic Arthritis, Inflammatory Arthritis, Osteoarthritis, Scaphoid Non-union Advanced Collapse (SNAC)
A Global Clinical Study Investigating the Safety and Effectiveness of Smith and Nephew's Porous Knee System in Patients Who Need a Total Knee Replacement Due to Degenerative Arthritis, Post-traumatic Arthritis or Inflammatory Arthritis
Recruiting
A clinical trial investigating the safety and effectiveness of Smith and Nephew's FDA-approved Porous Total Knee System, which is used to replace worn away and diseased knee joints. The aim of this study is to show that most patients who receive the Porous Total Knee System have reduced pain, greater mobility and a long-lasting implant post-surgery.
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
11/10/2023
Locations: Orthopaedic Specialists of Connecticut, Brookfield, Connecticut +23 locations
Conditions: Osteoarthritis, Post-traumatic Arthritis, Rheumatoid Arthritis
Actis Total Hip System 2 Year Follow-up
Recruiting
Two-year (2 year) information regarding the performance of the commercially available Actis™ Total Hip System in order to obtain and evaluate the clinical outcomes on a series of cementless primary total hip arthroplasty (THA) and hemi-hip arthroplasty procedures using clinical, radiographic and device and procedure related adverse event assessments.
Gender:
All
Ages:
21 years and above
Trial Updated:
10/10/2023
Locations: Not set, Louisville, Kentucky +9 locations
Conditions: Osteoarthritis, Traumatic Arthritis, Rheumatoid Arthritis, Congenital Hip Dysplasia, Avascular Necrosis of the Femoral Head, Acute Traumatic Fracture of the Femoral Head or Neck, Certain Cases of Ankylosis, Non-union of Femoral Neck Fractures, Certain High Sub-Capital & Femoral Neck Fractures in Elderly
Geniculate Artery Embolization for Treatment of Osteoarthritis
Recruiting
Single-arm, single-center, no sham or placebo, prospective pilot trial designed to evaluate the feasibility and safety of transcatheter arterial embolization in patients with mild to moderate radiographic knee OA. Eligible participants will receive geniculate artery embolization using Embozene™ Color-Advanced Microspheres. Patients will be followed up for a total of 12 months.
Gender:
All
Ages:
Between 30 years and 80 years
Trial Updated:
10/02/2023
Locations: NYU Langone Health, New York, New York
Conditions: Osteoarthritis
Colchicine for the Treatment of Osteoarthritis of the Knee
Recruiting
This prospective, double-blinded, placebo-controlled, randomized trial will enroll 120 SKOA subjects at the NYU Center for Musculoskeletal Care. Patients meeting entry criteria will be randomized 1:1 to treatment with colchicine or placebo daily for 3 months. Subjects will have detailed evaluation of standardized clinical pain outcomes, candidate peripheral blood biomarkers, baseline knee radiographs as well as MSK-US, and a subset will undergo evaluation of their synovial fluid.
Gender:
All
Ages:
Between 18 years and 99 years
Trial Updated:
09/26/2023
Locations: NYU Langone Health, New York, New York
Conditions: Osteoarthritis, Osteo Arthritis Knee
Open-label Trial to Check the Safety and Tolerability of RTX-GRT7039 Injections for Pain Associated With Osteoarthritis of the Knee
Recruiting
An open-label, single-arm clinical trial to confirm the safety of monoarticular injections or bi-lateral intra-articular injections of RTX-GRT7039 in patients who have pain associated with osteoarthritis of the knee despite standard of care.
Gender:
All
Ages:
18 years and above
Trial Updated:
09/25/2023
Locations: Arizona Arthritis and Rheumatology Associates (AARA) P.C, Glendale, Arizona +80 locations
Conditions: Osteoarthritis
Comparison of a Single RTX-GRT7039 and Placebo Intra-articular Injection for Pain Associated With Osteoarthritis of the Knee
Recruiting
A double-blind, randomized, placebo-controlled, parallel-group, multi-site, clinical trial to confirm the efficacy and safety of single injection of RTX-GRT7039 versus placebo in patients who have pain associated with osteoarthritis of the knee despite standard of care.
Gender:
All
Ages:
18 years and above
Trial Updated:
09/25/2023
Locations: Achieve Clinical Research, LLC, Birmingham, Alabama +69 locations
Conditions: Osteoarthritis
Post Market Clinical Follow-up (PMCF) Study of the A.L.P.S. Proximal Humerus Plating System
Recruiting
This study is a multicenter, prospective, non-randomized, non-controlled post-market clinical follow-up study. The primary objective of this study is to confirm the safety and performance of the A.L.P.S. Proximal Humerus Plating System applied in proximal humerus fracture treatment.
Gender:
All
Ages:
18 years and above
Trial Updated:
09/22/2023
Locations: Foundation for Orthopaedic Research & Education, Tampa, Florida +1 locations
Conditions: Osteoarthritis, Rheumatoid Arthritis, Post-Traumatic Arthritis, Psoriatic Arthritis, Proximal Humeral Fracture