There are currently 28 active clinical trials seeking participants for Osteoarthritis research studies. The states with the highest number of trials for Osteoarthritis participants are Florida, California, Texas and Pennsylvania.
Multi-Vendor Multi-Site Novel Accelerated MRI Relaxometry
NCT04536103
Recruiting
Currently the diagnosis of OA is based on radiographs and clinical findings, which is limited to detecting late-stage disease. There is a pressing, unmet clinical need for robust assessment of early changes in cartilage health. Towards this goal, extensive efforts are ongoing to develop quantitative MRI for cartilage matrix analysis. MR T1ρ and T2 relaxation times have shown to be promising imaging biomarkers for early cartilage degeneration and prediction of disease progression. However, many c... Read More
Gender:
All
Ages:
Between 18 years and 50 years
Trial Updated:
03/06/2024
Locations: Cleveland Clinic Foundation, Cleveland, Ohio
Conditions: Bone Diseases, Infectious, Musculoskeletal Diseases, Joint Diseases, Osteoarthritis, ACL Tear, Cartilage Degeneration
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SakuraBead Used As Resorbable Embolic for Genicular Artery Embolization
NCT06550024
Recruiting
An open label, prospective, two-arm, multicenter, randomized controlled trial comparing SakuraBead genicular artery embolization (GAE) with a control (corticosteroid injection).
Gender:
ALL
Ages:
Between 40 years and 79 years
Trial Updated:
03/21/2025
Locations: IR Centers, Raleigh, North Carolina +2 locations
Conditions: Osteo Arthritis Knee, Joint Diseases, Musculoskeletal Diseases, Rheumatic Diseases, Arthritis, Osteoarthritis
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Cemented Vs Cementless Persona Keel RCT
NCT05630053
Recruiting
The main objective of this study is to evaluate the safety, performance, and clinical benefits of the Persona Keel cementless and cemented knee.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/21/2025
Locations: Centura Health, Westminster, Colorado +7 locations
Conditions: Knee Pain Chronic, Rheumatoid Arthritis, Osteoarthritis, Traumatic Arthritis, Polyarthritis, Avascular Necrosis, Varus Deformity, Valgus Deformity, Flexion Deformity of Knee
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An Study to Evaluate Safety and Tolerability of OA-SYS in Subjects with Moderate to Severe Osteoarthritis of the Knee Joint
NCT06485843
Recruiting
This study is being conducted to evaluate the safety and tolerability of OA-SYS in patients with moderate to severe OA of the knee joint.
Gender:
ALL
Ages:
Between 35 years and 75 years
Trial Updated:
02/28/2025
Locations: Orthopedic & Sports Medicine Institute of Las Vegas, Las Vegas, Nevada
Conditions: Osteoarthritis, Osteo Arthritis Knee
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Postoperative Hip Precautions After Total Hip Arthroplasty Via the Posterior Approach: a Prospective Randomized Trial
NCT02686528
Recruiting
The purpose of this study is to determine if hip precautions, which are instructions that limit functional use of a hip replacement after surgery, affect the rate of dislocation in the first six weeks after primary total hip replacement surgery. The impact of hip precautions on a patient's return to activities of daily living and overall patient satisfaction will also be investigated. The overall cost effectiveness of hip precautions will be determined.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/25/2025
Locations: Rush University Medical Center, Chicago, Illinois
Conditions: Osteoarthritis, Degenerative Joint Disease
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Sustained Acoustic Medicine for Osteoarthritis Pain
NCT05254574
Recruiting
The purpose of this study is to compare Sustained Acoustic Medicine treatment to topical pain relief gel for the symptomatic management of osteoarthritis. The study will measure pain and function scores for patients undergoing treatment.
Gender:
ALL
Ages:
Between 35 years and 85 years
Trial Updated:
02/24/2025
Locations: James A Haley Veterans Hospital, Tampa, Florida
Conditions: Osteoarthritis
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A Prospective, Clinical Investigation of the Vanguard 360 Revision Knee
NCT01542580
Recruiting
The purpose of this study is to evaluate performance of the Vanguard 360 revision knee system utilizing offset on either the tibial component, femoral component, or both in terms of the restoration of mechanical alignment, clinical outcomes and survivorship.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/20/2025
Locations: Illinois Bone and Joint, Morton Grove, Illinois +11 locations
Conditions: Osteoarthritis, Rheumatoid Arthritis, Traumatic Arthritis, Post Traumatic Deformity, Complications; Arthroplasty, Deformity of Limb
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Low Level Laser Therapy (LLLT) for the Treatment of Hand Osteoarthritis.
NCT04692597
Recruiting
This study is a randomized, control trial of Active Duty and DoD Beneficiaries, age 18 years or older, with complaints of hand osteoarthritis. Subjects will be randomized into one of two groups receiving either LLLT or sham LLLT. Subjects will receive LLLT or sham LLLT weekly over a period of six weeks. At each visit, patients will rate their pain using the Defense and Veterans Pain Rating Scale (DVPRS) and assess their functionality using the Disabilities of the Arm, Shoulder, and Hand (DASH) q... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/06/2025
Locations: Mike O'Callaghan Military Medical Center, Nellis Air Force Base, Nevada
Conditions: Low Level Laser Therapy, Osteoarthritis, Family Medicine, Pain Management, Integrative Medicine
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Outcomes of Low-Impact Exercise Program for People with Ankle, Knee, And/or Hip Pain
NCT03711773
Recruiting
The primary objective of this study is to study how low-impact group exercise classes affect pain scores in patients with knee, hip, and ankle pain when paired with concurrent standard of care dietitian and behavioral health consults.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/06/2024
Locations: Missouri Orthopaedic Institute, Columbia, Missouri
Conditions: Osteoarthritis, Osteoarthritis, Knee, Osteoarthritis, Hip, Osteoarthritis Ankle
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ARVIS TKA vs Conventional TKA
NCT06663384
Recruiting
This study is a pilot analysis of a novel augmented reality guidance platform, the augmented reality visualization and information system (ARVIS, Insight Medical), with aims to demonstrate accuracy of bone resection and implant alignment during kinematic alignment total knee arthroplasty.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/04/2024
Locations: Florida Orthopaedic Institute, Tampa, Florida
Conditions: Osteoarthritis
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Temporary Peripheral Nerve Stimulation System for Osteoarthritis of the Knee
NCT06152029
Recruiting
The purpose of this study is to demonstrate the treatment outcomes of patients with chronic knee pain secondary to osteoarthritis that have received a temporary peripheral nerve stimulation system.
Gender:
ALL
Ages:
21 years and above
Trial Updated:
11/27/2024
Locations: Aurora Health Center, Fond Du Lac, Wisconsin +1 locations
Conditions: Osteoarthritis, Knee, Osteoarthritis
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A Prospective Total Joint Surgery Registry to Monitor Short- and Long-Term Clinical Outcomes
NCT06687109
Recruiting
The investigators propose a prospective longitudinal registry study to collect and compare preoperative and postoperative information from patients who undergo total joint arthroplasty (TJA). Outcomes will be assessed with common, routinely available patient-reported outcomes measures (PROM's) such as the HOOS Jr., Oxford score, Knee Society Score, Harris Hip Score, and other patient satisfaction and function assessments in use in Orthopedics.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/11/2024
Locations: Spokane Joint Replacement Center, Spokane, Washington
Conditions: Osteoarthritis
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