There are currently 279 active clinical trials seeking participants for Cancer research studies. The states with the highest number of trials for Cancer participants are California, Texas, New York and Florida.
Association Between Exercise, Patient-Reported Outcomes, and Clinical Events in Adult Cancer Survivors
NCT07030686
Recruiting
This protocol is a retrospective study using observational data to conduct a target trial emulation to examine the association of exercise on cancer specific endpoints and other clinical outcomes in cancer survivors.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/02/2025
Locations: Memorial Sloan Kettering Cancer Center (All Protocol Activities), New York, New York
Conditions: Survivorship, Recurrent, Recurrence, Cancer, Remission
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An Internet-based Program to Help Cancer Survivors Manage Pain
NCT04462302
Recruiting
To determine whether an Internet-based pain coping skills program plus enhanced usual care, compared to enhanced usual care alone, yields significant improvements in the co-primary outcomes of pain severity (as measured by the Brief Pain Inventory (BPI)) and pain interference (also measured by the BPI) from baseline to the post-intervention assessment for cancer survivors with persistent pain.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/01/2025
Locations: Mercy Hospital Fort Smith, Fort Smith, Arkansas +149 locations
Conditions: Cancer
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Symptom Management for Rural-Urban Cancer Survivors and Caregivers
NCT05360498
Recruiting
As the population of cancer survivors increases substantially, meeting the health care and psychosocial needs of this population has become a national priority. After treatment ends, cancer survivors still experience a range of physical and psychological symptoms that require management. The post-treatment period can present new challenges for many survivors as they encounter communication gaps in the transition from oncology to primary care, leaving unmet needs for information and management of... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/30/2025
Locations: KRMC WL Nugent Cancer Center, Kingman, Arizona +1 locations
Conditions: Cancer, Cancer Survivors, Informal Caregivers, Psychological Distress
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Testing Gene PilotLX With Latinx Cancer Patients
NCT06476938
Recruiting
This is a randomized controlled trial designed to evaluate the efficacy of an electronic health decision support tool called Gene PilotLX to increase informed decision making regarding hereditary risk information from tumor genomic profiling (TGP) test among Latinx cancer patients recruited at four cancer centers.
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
06/30/2025
Locations: MD Anderson Cancer Center at Cooper, Camden, New Jersey +3 locations
Conditions: Cancer
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Solid Tumor Analysis for HLA Loss of Heterozygosity (LOH) and Apheresis for CAR T- Cell Manufacturing
NCT04981119
Recruiting
Objective: To collect information on how often a solid tumor cancer might lose the Human Leukocyte Antigen (HLA) by next generation sequencing and perform apheresis to collect and store an eligible participant's own T cells for future use to make CAR T-Cell therapy for their disease treatment. Design: This is a non-interventional, observational study to evaluate participants with solid tumors with a high risk of relapse for incurable disease. No interventional therapy will be administered on... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/30/2025
Locations: Banner Health, Gilbert, Arizona +13 locations
Conditions: Solid Tumor, Adult, Colorectal Cancer, Non Small Cell Lung Cancer, Pancreatic Cancer, CRC, NSCLC, Pancreas Cancer, Mesothelioma, Ovarian Cancer, Ovarian Neoplasms, Ovarian Carcinoma, Mesothelioma, Malignant, Mesothelioma; Lung, Cancer, Triple Negative Breast Cancer (TNBC), Renal Cell Carcinoma (Kidney Cancer), Head and Neck Squamous Cell Carcinoma HNSCC
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A Randomized Trial of a Mobile Health Exercise Intervention for Older Adults With Myeloid Neoplasms
NCT04981821
Recruiting
This is a phase 2 randomized controlled trial (RCT) to assess the preliminary efficacy of the a mobile health exercise intervention (GO-EXCAP) versus a chemotherapy education control in 100 older patients with MN receiving outpatient chemotherapy on physical function and patient-reported outcomes (fatigue, mood, and quality of life). We will also explore the effect of the intervention on TNFα and related cytokine gene promoter methylation and their gene and protein expression.
Gender:
ALL
Ages:
60 years and above
Trial Updated:
06/30/2025
Locations: University of Rochester Medical Center/Wilmot Cancer Institute, Rochester, New York
Conditions: Cancer, Myeloid Neoplasm
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A Single Arm Pilot Trial of a Social Network Intervention
NCT05745038
Recruiting
The purpose of this study is to see if a social network support program (SOcial Networks to Activate Trust \& Adherence or SONATA) is helpful for older individuals receiving cancer treatment. The SONATA program will last for about 4 months. There are a total of 6 coaching sessions. The first 5 sessions will be held approximately every 1 to 2 weeks. Session 6 or the final session will be held approximately 1 to 2 months after session 5. Each session will last for about 1 to 2 hours.
Gender:
ALL
Ages:
60 years and above
Trial Updated:
06/30/2025
Locations: University of Rochester, Rochester, New York
Conditions: Cancer
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A Nutrition & Exercise Prehabilitation Intervention on Inflammatory Biomarkers in AI Cancer Patients
NCT06644560
Recruiting
The purpose of this study is to assess the feasibility of a prehab intervention among American Indian (AI) patients diagnosed with obesity-related cancer and measure inflammatory biomarkers to evaluate the preliminary impact of the trial intervention. The central hypothesis is that this community-informed prehab intervention will demonstrate feasibility, patient acceptability, and modulation of host and tumor-microenvironment inflammatory biomarkers. Aim 1: Implement the prehab translational cl... Read More
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
06/30/2025
Locations: University of Arizona Cancer Center, Tucson, Arizona
Conditions: Cancer, Obesity
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Working Through Outreach, Navigation and Digital Enabled Referral and Recruitment Strategies (ACT WONDER²S)
NCT06560398
Recruiting
The purpose of the study is to refine, finalize, implement, and evaluate a multi-level intervention aimed at increasing enrollment of Black and Hispanic patients to National Cancer Institute (NCI)-sponsored therapeutic clinic trials at Moffitt Cancer Center.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/30/2025
Locations: Moffitt Cancer Center, Tampa, Florida
Conditions: Cancer
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Evaluation of Late Effects and Natural History of Disease in Patients Treated With Radiotherapy
NCT00026650
Recruiting
BACKGROUND * This protocol acknowledges that it is in the interest of the NIH and ROB, as well as our participants, to continue to follow those who have been treated with radiotherapy at ROB and are not otherwise eligible for current active research protocols. * It also provides a mechanism for the correlation and interpretation of disparate data for research into the long term side effects and outcomes for a variety of disease entities and treatments, such as combined modality treatment, MoAb,... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/28/2025
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Cancer
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Tumor Related Epilepsy
NCT02639325
Recruiting
Background: Some people with brain tumors have seizures related to the tumor. This is called tumor-related epilepsy. Usually brain tumors are treated by removing as much of the brain tumor as possible without causing problems. Researchers think this may improve the outcome for people with brain tumors. It may completely relieve or greatly reduce the number of seizures they have. Objectives: To evaluate people with brain tumors that are associated with seizures and to offer surgical treatment.... Read More
Gender:
ALL
Ages:
Between 8 years and 99 years
Trial Updated:
06/28/2025
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Epilepsy, Cancer, Brain Neoplasm
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Dose Escalation Study Evaluating Safety of TheraSphere Prostate Cancer (PCa) Device
NCT06192758
Recruiting
The VOYAGER Study is an interventional, non-randomized, single-arm, dose escalation trial with the goal of determining the safety of TheraSphere PCa device in patients with clinically localized prostate cancer across US-based centers.
Gender:
MALE
Ages:
50 years and above
Trial Updated:
06/26/2025
Locations: Ronald Reagan UCLA Medical Center (UCLA Health, Los Angeles), Los Angeles, California +4 locations
Conditions: Prostate, Cancer
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